The only psychopaths that can be defeated are the ones that the ruling psychopaths allow to be defeated, usually to keep the attention off of them. No institution, whether it is an elected government or its bureaucracy, nor a corporation, will allow the psychopathic ranks at the top to be removed. The very characteristics of their psychopathy are the very characteristics they need to maximize their objectives (be they profits, laws or enforcement). Since corporations have no conscience, they may as well be psychopaths and, therefore, cannot be counted upon to "do the right thing". For every example one can find of benevolent organizations (and there certainly are some), thousands of examples of the opposite can be provided.
We don't deal in opinions here, just evidence, and there is little to no evidence that the psychopaths who are the greatest threat to mankind can actually be beaten systematically.
Although open revolution might be a way, there's a good chance the leadership of such a movement would be successfully infiltrated by psychopaths with their own agenda and we'd end up with, meet the new boss, same as the old boss. So, we can't trust the institutions to clean house due to their own desire for self preservation, and we can barely trust each other to organize an effective revolution, considering how easily our fellow compatriots fall under the spell of psychopaths. We only need to look at the results of most elections to see democratically elected pathocrats.
If you haven't had a chance to read "Political Ponerology: A Science on the Nature of Evil Adjusted for Political Purposes" by Andrew M. Lobaczewski, you'd probably enjoy it, since you seem interested in the subject. Many of us read Hare and Cleckley before coming across Lobaczewski and were quite impressed with his more holistic view of the effects of psychopathy on society.