Science > Diet and Health

Dr. Jack Kruse - Neurosurgeon

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Psyche:
I had the opportunity to read his posts on thermogenesis, the holy trinity, the quilt, the leptin Rx FAQ, and downloaded some of the papers and articles that he cites. What Odyssey synthesized sums what I read pretty well.  He babbles a lot, it seems he literally types as he thinks and does no editing. I think he is reviewing a ton of information in a very short time. He goes almost by instinct but also experience as he reviews the science that is available. What he is finding sounds fascinating to me, but it requires a lot of research background. I hope he writes a book soon, and I hope he has a very good editor!

It also strikes me that he points out that people who are interesting in long-term performance and longevity with a ketogenic version of the paleolithic diet (which is basically what we do) show incredible results and huge gains in their performance over 24-36 months of adaptation. He is been doing it for almost 6 years and also in his patients.

It makes me wonder what else the Ice Age will do to our bodies and brains, provided we are ready and survive it...

SeekinTruth:
Yes, I've been thinking about this whole cold adaptation/cold thermogenisis issue and the Ice Age. I listened to the Underground Wellness podcast dugdeep linked to. It was also pretty interesting. I agree that he doesn't edit his writing AT ALL.

The other thing that keeps niggling at me in the back of my mind is that he keeps referring to cold adapted mammals being our "ancestors" and never mentions (as far as I've run into) the long periods of Ice Age humans evolved through. One other thing that surprised me on that podcast was that he talked more about eating seasonally and the whole circadian biology, etc. He said that starting from around March 15 to April 15, he started increasing his carbs, and hits from 200 to 300 grams by summer!! Why would anybody do this and then go back to being keto adapted in the fall? Sounds like something I would NOT want to do. But then he said he's no longer going to do this/no longer is doing it, but I didn't understand the reason he gave. If anybody else listened to the podcast and remembers, did you understand why he said he gave up increasing carbs so much in spring and summer?

In any case, when I have some time, I've been planning on going through more of the material on his website and I might post some summaries again in this thread.

truth seeker:

--- Quote from: SeekinTruth on March 12, 2012, 05:35:28 PM ---He said that starting from around March 15 to April 15, he started increasing his carbs, and hits from 200 to 300 grams by summer!! Why would anybody do this and then go back to being keto adapted in the fall? Sounds like something I would NOT want to do. But then he said he's no longer going to do this/no longer is doing it, but I didn't understand the reason he gave. If anybody else listened to the podcast and remembers, did you understand why he said he gave up increasing carbs so much in spring and summer?

--- End quote ---
As I understood it, he said he's not doing it this summer because he's continuing his biohacks this summer:

https://en.wikipedia.org/wiki/Biohacking


--- Quote ---The second meaning of biohacking refers to the art of managing one's own biology using a combination of medical, nutritional, electronic, and Quantified Self techniques. The term is in common use by several public figures:

    Tim Ferriss wrote about biohacking in 4_Hour_Body#The_4-Hour_Body

    Dave Asprey of "The Bulletproof Executive" [1] about whom the Financial Times wrote "Indeed, why not give yourself an 'upgrade', says Dave Asprey, a 'bio-hacker' who takes self-quantification to the extreme of self-experimentation. He claims to have shaved 20 years off his biochemistry and increased his IQ by as much as 40 points through 'smart pills', diet and biology-enhancing gadgets."1

    Neurosurgeon Jack Kruse who writes "Our hypothalamus rewires to many stimuli and it appears that temperature is a major factor in the rewiring protocol of our brain...Our job as enquiring primal bio-hackers is to figure out why and how this might have happened.
--- End quote ---

Psyche:

--- Quote from: SeekinTruth on March 12, 2012, 05:35:28 PM ---
The other thing that keeps niggling at me in the back of my mind is that he keeps referring to cold adapted mammals being our "ancestors" and never mentions (as far as I've run into) the long periods of Ice Age humans evolved through. One other thing that surprised me on that podcast was that he talked more about eating seasonally and the whole circadian biology, etc. He said that starting from around March 15 to April 15, he started increasing his carbs, and hits from 200 to 300 grams by summer!! Why would anybody do this and then go back to being keto adapted in the fall? Sounds like something I would NOT want to do. But then he said he's no longer going to do this/no longer is doing it, but I didn't understand the reason he gave. If anybody else listened to the podcast and remembers, did you understand why he said he gave up increasing carbs so much in spring and summer?

--- End quote ---

I haven't heard his podcasts, I generally prefer to read. He explains the no safe starch thing on his Thermogenesis series, but probably it is elsewhere in his blog as well. He gives several explanations, but the one that stands out for me is that the cells age faster when they use carbs as energy source since there is more oxidation as a by product. He gives a link to one of his posts on the use of energy by cells, but we have also a synthesis on energy utilization in Life Without Bread showing how ketogenic energy sources are more effective.

In simple words, I would say that people are living in a "perpetual summer" and then we are no longer reading from the environment the correct signals to switch the "longevity" hormones in our bodies during winter because we have artificial means to keep warm and have light and carbs all through the year. Physiologically, we still have the capacity to switch this "longevity" hormones though.

SeekinTruth:
Ahh, thanks truth seeker, I wasn't able to make out "biohacks" in the podcast (the audio wasn't great).

Psyche, I did get the gist of what you wrote from browsing through his site. The thing I'm questioning is: is it good to go through the switch of metabolism -- fat burning to sugar burning and back every year? You have to get knocked out of ketosis if you go up to 200 to 300 grams of carbs, right. It's probably individual, but I'm thinking the upper level to stay in ketosis will be somewhere in the range of 50 to 70 grams of carbs.

Anyway, maybe I'm missing something important like when you've been doing it for a long enough time, it's not a big deal to switch metabolism back and forth in terms of how long it takes to adapt/adjust?

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