Survival genes: Scientists find DNA mutations that helped Russians during war

Keit · Jun 23, 2015

There is an article posted on SOTT today about unique DNA mutations found in Russian people that survived the Leningrad siege in WWII. Sorry for creating a new thread. I remember that there was a discussion about it somewhere on the forum, so please moderators move it there if needed.

In any case, those researchers have some very interesting things to say:

Many siege survivors who suffered the worst turned out to have a completely different structure of two genes related to PPAR (peroxisome proliferator-activated receptors) proteins, and one from the UCP (uncoupling proteins) gene family, which play major roles in development, metabolism and thermogenesis of higher organisms.

The inhabitants of the besieged city, now known as St. Petersburg, had these genes undergo a mutation that increased the efficiency of the cells' activities and reduced the loss of energy invested in keeping the body warm, according to an article, recently published in the journal Science.

The project started about 15 years ago, when professor Oleg Glotov from the Ott Research Institute of Obstetrics and Gynecology in St. Petersburg, along with his colleagues, decided to study the problems of aging and longevity.

They collected some 200 blood samples of the aged, noticed some intriguing differences and decided to narrow their research to focus on the toughest ones - those people, who survived the siege and whose diet was limited by the harsh conditions of wartime.

"Genetic predisposition alongside with other factors was that very sieve which those siege survivors had to pass and managed to survive in that demanding environment. Absolutely, those genes did not emerge by chance, in other words, those people already had them," Glotov told RT. "About 20 to 30 percent of the population has those markers."

"In harsh conditions they presented an advantage. In a stuffed environment, vice versa, they will be a disadvantage: in the case of overeating they will contribute to the accretion of energy in the form of fats, etc.," he added.

Notice what they say in the last paragraph. I remember that the C's said Laura something about Ark, that in the harsh conditions she will be able to give him her food (or something like that, sorry, don't remember exactly), because she won't need it. And there was also a discussion on the forum about people with specific genetic make up, that are built to survive better in extreme situations.

Very interesting...

Eboard10 · Jun 23, 2015

Just read the article on SOTT and the findings are quite fascinating. This actually reminds me of another article from a few years ago showing how the plagues in the Middle Ages made some individuals more resistant to certain viral infections as they carry a genetic mutation (CCR5-delta 32) that prevents a virus from getting into the immune system. I wonder if the different gene structure of these survivors is a mutation that goes back to the last Ice Age or even the more recent mini Ice Age, in the same way that some people have a genetic mutation that makes them more resilient to the plague.

http://www.sott.net/article/197427-Biologists-Discover-Why-10-Percent-Of-Europeans-Are-Safe-From-HIV-Infection

Biologists at the University of Liverpool have discovered how the plagues of the Middle Ages have made around 10% of Europeans resistant to HIV.

Scientists have known for some time that these individuals carry a genetic mutation (known as CCR5-delta 32) that prevents the virus from entering the cells of the immune system but have been unable to account for the high levels of the gene in Scandinavia and relatively low levels in areas bordering the Mediterranean.

They have also been puzzled by the fact that HIV emerged only recently and could not have played a role in raising the frequency of the mutation to the high levels found in some Europeans today.

Professor Christopher Duncan and Dr Susan Scott from the University's School of Biological Sciences, whose research is published in the March edition of Journal of Medical Genetics, attribute the frequency of the CCR5-delta 32 mutation to its protection from another deadly viral disease, acting over a sustained period in bygone historic times.

Some scientists have suggested this disease could have been smallpox or even bubonic plague but bubonic plague is a bacterial disease rather than a virus and is not blocked by the CCR5-delta 32 mutation.

Professor Duncan commented: "The fact that the CCR5-delta 32 mutation is restricted to Europe suggests that the plagues of the Middle Ages played a big part in raising the frequency of the mutation. These plagues were also confined to Europe, persisted for more than 300 years and had a 100% case mortality."

Around 1900, historians spread the idea that the plagues of Europe were not a directly infectious disease but were outbreaks of bubonic plague, overturning an accepted belief that had stood for 550 years. Professor Duncan and Dr Scott illustrated in their book, Return of the Black Death (2004, Wiley), that this idea was incorrect and the plagues of Europe (1347-1660) were in fact a continuing series of epidemics of a lethal, viral, haemorrhagic fever that used the CCR5 as an entry port into the immune system.

Using computer modeling, they demonstrated how this disease provided the selection pressure that forced up the frequency of the mutation from 1 in 20,000 at the time of the Black Death to values today of 1 in 10.

Lethal, viral haemorrhagic fevers were recorded in the Nile valley from 1500 BC and were followed by the plagues of Mesopotamia (700-450BC), the plague of Athens (430BC), the plague of Justinian (AD541-700) and the plagues of the early Islamic empire (AD627-744). These continuing epidemics slowly raised the frequency from the original single mutation to about 1 in 20,000 in the 14th century simply by conferring protection from an otherwise certain death.

Professor Duncan added: "Haemorrhagic plague did not disappear after the Great Plague of London in 1665-66 but continued in Sweden, Copenhagen, Russia, Poland and Hungary until 1800. This maintenance of haemorrhagic plague provided continuing selection pressure on the CCR5-delta 32 mutation and explains why it occurs today at its highest frequency in Scandinavia and Russia."

SeekinTruth · Jun 24, 2015

Fascinating. There may be other types of mutations that will become manifest in upcoming hard times too....

Nienna · Jun 24, 2015

Keit said:
Notice what they say in the last paragraph. I remember that the C's said Laura something about Ark, that in the harsh conditions she will be able to give him her food (or something like that, sorry, don't remember exactly), because she won't need it. And there was also a discussion on the forum about people with specific genetic make up, that are built to survive better in extreme situations.

Very interesting...

This mutation already being there in people and that once certain conditions are met, it sort of "activates" goes along with what Bryant M. Shiller said in his book Origins of Life: The 5th Option that mutations are not created by outside conditions, but that they are already in the genetic code and when certain conditions are met, they activate (I am really paraphrasing here).

Very interesting, Keit. Thanks for sharing.

Eboard10 · Jun 24, 2015

Nienna said:
Keit said:

Notice what they say in the last paragraph. I remember that the C's said Laura something about Ark, that in the harsh conditions she will be able to give him her food (or something like that, sorry, don't remember exactly), because she won't need it. And there was also a discussion on the forum about people with specific genetic make up, that are built to survive better in extreme situations.

Very interesting...

Click to expand...

This mutation already being there in people and that once certain conditions are met, it sort of "activates" goes along with what Bryant M. Shiller said in his book Origins of Life: The 5th Option that mutations are not created by outside conditions, but that they are already in the genetic code and when certain conditions are met, they activate (I am really paraphrasing here).

Very interesting, Keit. Thanks for sharing.

I am just speculating here but I wonder if there are two scenarios that can play out in general:

[list type=decimal]
[*]An already existing genetic code that has been dormant or inactive for a period of time is reactivated when certain outside conditions re-emerge

[*]A new genetic mutation is created following extreme external conditions that the generic code either hadn't been subjected to before, had limited exposure to in the past or didn't have the time to adapt to previously
[/list]

Chu · Jun 25, 2015

Very interesting! I hope that cold is not the only factor; because in spite of continuous trials, I don't think I'll ever be able to say that I'm cold adapted or mutated to survive it. It's more like "Freezing but cold-resigned" ;D

Eboard10 said:
[list type=decimal]
[*]An already existing genetic code that has been dormant or inactive for a period of time is reactivated when certain outside conditions re-emerge

[*]A new genetic mutation is created following extreme external conditions that the generic code either hadn't been subjected to before, had limited exposure to in the past or didn't have the time to adapt to previously
[/list]

Yeah, they both sound plausible to me, FWIW. There is so much that isn't known about genes, that you would think that there is a lot of "dormant" or "to be born" potential! Maybe the theory of information comes to play here as well, and depending on experiences, knowledge, lessons learned, etc, our genes act as "antennas" and we pick up more or less, change more or less depending on how much and in what quality our bodies are able to absorb. There would be physical conditions that trigger changes (new viruses, cold, hunger, etc.), but also the ability of each individual to "take in" that new information and mutate genes accordingly. I'm not sure this makes much sense, though. But the Cs once said that viruses were "thoughts made manifest", or something to that effect. So, our thoughts, knowledge and worldviews may open up doors that lead to adopting certain toxic "information" and dying, or learning to survive it.

RedFox · Jun 25, 2015

Very interesting!

Chu said:
Maybe the theory of information comes to play here as well, and depending on experiences, knowledge, lessons learned, etc, our genes act as "antennas" and we pick up more or less, change more or less depending on how much and in what quality our bodies are able to absorb. There would be physical conditions that trigger changes (new viruses, cold, hunger, etc.), but also the ability of each individual to "take in" that new information and mutate genes accordingly. I'm not sure this makes much sense, though. But the Cs once said that viruses were "thoughts made manifest", or something to that effect. So, our thoughts, knowledge and worldviews may open up doors that lead to adopting certain toxic "information" and dying, or learning to survive it.

Receivership capacity? Speaking of DNA as antenna (this peaked my antenna!).

http://www.ncbi.nlm.nih.gov/pubmed/21457072

DNA is a fractal antenna in electromagnetic fields.
Blank M1, Goodman R.
Author information
Abstract
PURPOSE:

To review the responses of deoxyribonucleic acid (DNA) to electromagnetic fields (EMF) in different frequency ranges, and characterise the properties of DNA as an antenna.
MATERIALS AND METHODS:

We examined published reports of increased stress protein levels and DNA strand breaks due to EMF interactions, both of which are indicative of DNA damage. We also considered antenna properties such as electronic conduction within DNA and its compact structure in the nucleus.
RESULTS:

EMF interactions with DNA are similar over a range of non-ionising frequencies, i.e., extremely low frequency (ELF) and radio frequency (RF) ranges. There are similar effects in the ionising range, but the reactions are more complex.
CONCLUSIONS:

The wide frequency range of interaction with EMF is the functional characteristic of a fractal antenna, and DNA appears to possess the two structural characteristics of fractal antennas, electronic conduction and self symmetry. These properties contribute to greater reactivity of DNA with EMF in the environment, and the DNA damage could account for increases in cancer epidemiology, as well as variations in the rate of chemical evolution in early geologic history.

https://en.wikipedia.org/wiki/Fractal_antenna

A fractal antenna is an antenna that uses a fractal, self-similar design to maximize the length, or increase the perimeter (on inside sections or the outer structure), of material that can receive or transmit electromagnetic radiation within a given total surface area or volume.

Such fractal antennas are also referred to as multilevel and space filling curves, but the key aspect lies in their repetition of a motif over two or more scale sizes,[1] or "iterations". For this reason, fractal antennas are very compact, multiband or wideband {meaning information can be transmitted/received on many frequencies at once}, and have useful applications in cellular telephone and microwave communications.

Oh boy, this one looks like a doozy of a thread to pull on!

http://www.technologyreview.com/view/419590/quantum-entanglement-holds-dna-together-say-physicists/

Quantum Entanglement Holds DNA Together, Say Physicists

Now a group of physicists say that the weird laws of quantum mechanics may be more important for life than biologists could ever have imagined. Their new idea is that DNA is held together by quantum entanglement.

That’s worth picking apart in more detail. Entanglement is the weird quantum process in which a single wavefunction describes two separate objects. When this happens, these objects effectively share the same existence, no matter how far apart they might be.

Quantum entanglement (or 'spooky action at a distance') can be used to transmit information instantaneously (zero time) over great distance.

The following should probably be taken with a pinch of salt (other publications from this site include papers on cold fusion), but potentially fits with the above when considered along side information theory.

http://iopscience.iop.org/1742-6596/306/1/012007/pdf/1742-6596_306_1_012007.pdf

DNA waves and water

Abstract.
Some bacterial and viral DNA sequences have been found to induce low frequency
electromagnetic waves in high aqueous dilutions. This phenomenon appears to be triggered by
the ambient electromagnetic background of very low frequency. We discuss this phenomenon
in the framework of quantum field theory. A scheme able to account for the observations is
proposed. The reported phenomenon could allow to develop highly sensitive detection systems
for chronic bacterial and viral infections.

The summary of which is as follows:
_http://www.bibliotecapleyades.net/ciencia/ciencia_genoma39.htm

A Nobel prizewinner is reporting that DNA can be generated from its teleported "quantum imprint" [..]
So what have Montagnier and his team actually found?

Full details of the experiments are not yet available, but the basic set-up is as follows. Two adjacent but physically separate test tubes were placed within a copper coil and subjected to a very weak extremely low frequency electromagnetic field of 7 hertz. The apparatus was isolated from Earth's natural magnetic field to stop it interfering with the experiment.

One tube contained a fragment of DNA around 100 bases long; the second tube contained pure water.

After 16 to 18 hours, both samples were independently subjected to the polymerase chain reaction (PCR), a method routinely used to amplify traces of DNA by using enzymes to make many copies of the original material.

The gene fragment was apparently recovered from both tubes, even though one should have contained just water (see below diagram).

DNA was only recovered if the original solution of DNA - whose concentration has not been revealed - had been subjected to several dilution cycles before being placed in the magnetic field.

In each cycle it was diluted 10-fold, and "ghost" DNA was only recovered after between seven and 12 dilutions of the original. It was not found at the ultra-high dilutions used in homeopathy.

Physicists in Montagnier's team suggest that DNA emits low-frequency electromagnetic waves which imprint the structure of the molecule onto the water.

This structure, they claim, is preserved and amplified through quantum coherence effects, and because it mimics the shape of the original DNA, the enzymes in the PCR process mistake it for DNA itself, and somehow use it as a template to make DNA matching that which "sent" the signal (DNA Waves and Water).

So (and this is mostly speculation) - it's possible that 'mutations' could spontaneously appear in an organism instantaneously (via quantum entanglement - all DNA changing at once), and perhaps even 'tribes'.
There does at least appear to be some interesting characteristics to DNA that may explain (quantum) a connection to information theory. Incidentally, nerve cells (and especially the brain) have a whole heap of stuff going on at the quantum level.

Eboard10 · Jun 26, 2015

Hi Redfox,

The research you shared, especially the part on quantum entanglement and quantum imprint reminds me a lot of Rupert Sheldrake's theory of morphogenetic fields and I think ties up nicely with the this excerpt of the transcripts:

Session 11 October 2014

Q: (L) And there was something else I wanted to ask that you guys made me think of... I had something, and it slipped out of my brain. I'm having a senior moment... OH! Is this full tribal unit strength capacity kind of what you meant way back when when you talked about "broader receivership capability", that it's not simply restricted to an individual, but that it's like creating a net that is kind of like an array of antennas that...

(Perceval) The signal received is spread throughout the array...

A: Yes yes yes!

Q: (L) Okay.

(PoB) This full tribal unit strength that affects progress and changes DNA and so on, does it happen progressively, or is it like yes or no?

(L) You mean like on or off?

(PoB) Yes.

A: Critical mass much involved.

Q: (L) So you have to hit a critical mass before it switches.

(Andromeda) So it's more like on/off.

(L) I would say there are SOME individual cumulative things, but the big changes depend on critical mass.

A: Yes.

So taking the self symmetry characteristic of fractal antennas and applying it to DNA would indeed mean that a mutation which is activated in a person or a small group of people could spread to many more in a relatively short period of time "as if by accident". The tribal unit could be one such group through which structural changes of the genetic code would more easily spread. In a way, we are all connected through the morphic field, more closely with people of the same tribal unit and to a lesser degree to others, so the spreading of information would be easier within such group. Yet, when such extreme events occur like with an ice age or a global pandemic, the genetic mutations can easily spread to other groups through the information field. The same changes can also be passed on generationally if one of the parents has that mutation.

A possible analogy would be that we belong to a global fractal antenna array, with many smaller arrays within it, each representing say a tribal unit. When a new external condition is present, the genetic structure mutates in a few individuals in order to better adapt and survive. If this mutation makes the body resilient to this condition, it then spreads to other members of the unit since receivership capacity is more in resonance. The same change in the DNA structure can then spread to other groups if the conditions are extreme or go on for a prolonged time.

Not sure if this makes complete sense but I thought I'd share my thoughts FWIW.

RedFox said:
DNA is a fractal antenna in electromagnetic fields.
Blank M1, Goodman R.
Author information
Abstract
PURPOSE:

To review the responses of deoxyribonucleic acid (DNA) to electromagnetic fields (EMF) in different frequency ranges, and characterise the properties of DNA as an antenna.
MATERIALS AND METHODS:

We examined published reports of increased stress protein levels and DNA strand breaks due to EMF interactions, both of which are indicative of DNA damage. We also considered antenna properties such as electronic conduction within DNA and its compact structure in the nucleus.
RESULTS:

EMF interactions with DNA are similar over a range of non-ionising frequencies, i.e., extremely low frequency (ELF) and radio frequency (RF) ranges. There are similar effects in the ionising range, but the reactions are more complex.
CONCLUSIONS:

The wide frequency range of interaction with EMF is the functional characteristic of a fractal antenna, and DNA appears to possess the two structural characteristics of fractal antennas, electronic conduction and self symmetry. These properties contribute to greater reactivity of DNA with EMF in the environment, and the DNA damage could account for increases in cancer epidemiology, as well as variations in the rate of chemical evolution in early geologic history.

This is quite scary when viewed in light of all the EM pollution that we are surrounded with!

Survival genes: Scientists find DNA mutations that helped Russians during war

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