Human physiology in an electric universe

Keyhole

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This information is taken from a lecture by Dr James Oschman at the "Electric Universe- The Human Story" conference. It presents a framework for understanding human physiology's relation to the electric universe. I have provided a summary containing images of some slides and bullet-pointed information for quick reading. The full video can be found at the bottom of the page.

How the cosmic matrix intersects with the living matrix

-This concept recognizes that our bodies are a continuum, as is the universe. All things are connected. The cell contains a matrix called the cytoskeleton, which contains another (nuclear) matrix, and is surrounded another one called the connective tissue matrix.

-Connective tissue is the largest organ, and one which touches all other structures. This is essentially an electronic circuit.

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-The interface between space within us is continuous with the space everywhere – plasma.

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-Old cell model as a bag of fluid: Outdated and wrong

-New model views the cell as an interconnected matrix within a matrix within a matrix.

- Integrin proteins penetrate through the plasma membrane and connect the intracellular matrix with the extracellular matrix to coordinate activity and transfer information. It is hardwired to the nuclear matrix and cytoskeleton. The links are both mechanical and energetic.

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-The living system – each cell is connected to every single other cell via the connective tissue, a continuous and holistic network. There is no place in the body that is not connected to this network.

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- Made of a remarkable material. A hydrated liquid crystal: Collagen – a triple helix of tropocollagen surrounded by hydration shell of water.
Collagen is a semiconductor, is piezoelectric, pyroelectric, thermoelectric, and is an electret.

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- Acupuncture system: Meridians are primary channels through the collagen matrix which facilitates high speed communication.

- This electronic network may be the energy and information system within the body. Communicates much faster than the nervous system.

- Grounding: Before modern times we were connected to the ground via bare foot connection to the earth. Slept on animal hide (which is semi-conducting collagen), or wore animal hide shoes.

- Electrons flow from the sun via solar wind to the ionosphere, are passed to the earth via lightning etc and are absorbed by earth.

- Electrostatics: Two conductive objects with different electrical potential touch each other, there is an instantaneous transfer of charge so that both objects equilibrate to the same electrical potential. In this context: the human body and the earth.

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- The ball of the foot at “Kidney point 1” connects the entire collagen connective tissue/meridian network in the body to the earth. This allows for continuous flows of electrons into the electronic circuit.

-This practice:
• improves sleep,
• decreases pain,
• decreases inflammation (electrons are nature’s antioxidants),
• Increases relaxation (via autonomic nervous system activation)
• Accelerates injury healing
• Increased heart rate variability
• Reduced blood viscosity

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-Mitochondria are connected to the living matrix. Electrons are needed to produce ATP (needed for cellular processes) and can be acquired via this flow. All biochemical reactions are redox reactions, which means to transfer for electrons.

-Free radicals/oxidative stress can be attributed to all disease generation and aging. This can be likened to an “electron deficiency”. Connecting to the ground may be one of the most powerful tools to counteract oxidative strsss.

How does the cosmic matrix interact with the living matrix?

-The human body is an organic liquid crystal. Collagen is the building block of the body, a highly structured triple helical structure.

-Albert Szent-Gyorgi quote: “The proteins are the stage upon which the drama of life unfolds. The actors can be none other than small and highly mobile units such as electrons and protons”

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-Alternative and Complementary medicine: possibly the practitioners ability to influence the flow of electrons/protons in the semiconducting system, and can transfer this information to the patient.

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-Quantum physist Vladimir B. Ginzburg theorizes that the “fabric of space has a spiral grain”

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The cornea of the eye is composed of layers of collagen which are slightly offset and possibly causes light to enter the eye in a spiral manner unobstructed.

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Video Lecture:

https://youtu.be/tGylGdNrG4o

Note: Next post to follow on will include biophoton theory lecture
 
Supporting paper for the previous lecture by Dr Mae-Wan Ho discussing the fascia network and acupuncture meridian system. It fits in nicely with the electric universe and information theory.

A medical physicist in the United States, Cho Zang-Hee, who pioneered the proton emission tomography (pet) scanner, had his curiosity aroused 6 years ago, when he injured his back and found almost instant relief with acupuncture treatment. So he started carrying out experiments with functional magnetic resonance imaging (fmri) on the usual human guinea-pigs - volunteer medical students. He flashed a light in front of them and, as expected, the visual cortex of the brain lit up on the fmri. Then, Cho had an acupuncturist stick a needle into one of the acupoints at the side of the little toe, which are supposed to be connected with the eye. In one person after another, the visual cortex lit up, just as if they had been stimulated with a flash of light. Inserting the needle into a non-acupoint in the big toe had no effect (see Dold, 1998).

Cho also found that on repeated stimulation of the same acupoints, some subjects gave increasing response in the visual cortex, while others gave decreasing response. One of the acupuncturist said it was due to yin and yang, and without seeing the data, correctly identified which subjects had an increase (yang) and which had a decrease (yin) in 11 out of 12 cases.

The only explanation for acupuncture in the west is that the nerves underlying the muscles are stimulated by the needle, which then sends impulses to the limbic system of the brain, the mid-brain and the pituitary, leading to the release of endorphins and monamines, chemicals which block pain perception. This is the accepted basis for anaethesia induced by acupuncture. But it does not explain other effects. It certainly does not explain what connects the acupoints in the foot directly to the visual cortex of the brain.

The meridian theory of traditional Chinese medicine recognizes a vital energy, qi, circulating in nature and in our body. Within the body, qi is said to circulate through channels known as meridians. The meridians interconnecting the viscera and limbs, the deeper and superficial layer of the body in a branching network of increasingly fine mesh. The meridians and their acupoints have no known relationship with anatomical systems in western medicine, despite many attempts to search for correlations (see Ho and Knight, 1998).

Until quite recently, I have thought little about acupuncture. Instead, I have been involved, since 1985, in trying to understand living organisation from the perspective of contemporary physics, especially of non-equilibrium thermodynamics and quantum theory. At the same time, I was developing and using new experimental approaches to investigate organisms non-destructively, as they are living and developing. As a result, I have now come to an understanding of the organism that is beginning to connect with the meridian theory, and, I hope, in due course, with holistic health systems of all other cultures. I have outlined a tentative theory of the organism in the second edition of my book, The Rainbow and the Worm, the Physics of Organisms (Ho, 1998). Let me briefly describe it and then show how it may link up with the meridian theory.

Many physicists have puzzled over how organisms seem able to resist the second law of thermodynamics which says all systems tend to evolve towards thermodynamic equilibrium - a state of maximum disorder in which all useful energy has degraded into a random, useless form referred to as entropy. Instead, organisms can summon energy at will in a perfectly coordinated way, and to maintain and reproduce its exquisite organisation. Everyone knows that because the organism is an open system, it does not actually violate the second law, because the environment provides raw materials and useful energy and becomes more disordered as organisation is built up and maintained in the system, and entropy exported out of it. But how does the organism actually do it?

It turns out that the key to living organisation is not so much energy flow as energy storage under energy flow. Furthermore, the organism has somehow managed to close the loop of energy storage to become a self-maintaining, self-reproducing life-cycle.

The organism is thus a system in which energy is stored in a coherent form, the energy remaining coherent as it is mobilized throughout the system. Notice that I have substituted ‘coherent energy’ for the usual concept of ‘free energy’. Coherent energy, as I shall explain presently, is stored in a range of space-times in which it remains coherent, and is tied to the characteristic space-times of natural processes. I say ‘characteristic space-time’ instead of the usual ‘characteristic time’ because in the new physics since Einstein's relativity theory, space and time are no longer separable. (Indeed, organic space-time is very different from the linear, homogeneous, space and time of Newtonian physics (see Ho, 1998).) ‘Free energy’, on the other hand, has no relationship to space or time, and is a notoriously vague concept.

Coherent energy is energy that comes and goes together so it can do work, as opposed to incoherent energy which cancels itself out. Anyone ever hit by a wave on the seashore will know what coherent energy is as opposed to the random motion of say, molecules of air in this room. Coherent energy is mobilised within the organism with minimum dissipation, which means it generates minimum entropy. This depends on a symmetrical coupling of energy yielding and energy requiring processes within the living system. Symmetrical coupling involves a complete reciprocity, so that the effects of one process on the other are the same, and furthermore, they can reverse roles so the giver of energy becomes the receiver and vice versa. How is that achieved?

Practically all living processes are organised in cycles. The organism is thick with biological rhythms ranging from periods of split seconds for electrical activities of brain cells to seconds such as the heart-beat and respiration, to periods which are circadian and circannual. But no one has ever been able to explain why that should be. The answer is provided by thermodynamics. It turns out that symmetrically coupled cycles are the key to both the conservation of coherent energy and compensation (or cancelling out) of entropy within the system so that living organisation is maintained.
[..]
The way to think about it is that as one cycle of activity is running down, it is charging up a second cycle, so that the role can be reversed later. Similarly, as disorder is created in some part of the system, a kind of superorder appears in elsewhere, which can restore order to the first part.

Each cycle of activity has a characteristic space-time and together, they span all space-times from the very fast to the very slow, the global to the local. Each cycle is hence a domain in which coherent energy is stored, as said earlier. Of course, neither the conservation of coherent energy nor the compensation of entropy is perfect, otherwise, no one would ever need to eat, nor would ever age. But such a dynamic structure of the system is the key to maximising the storage of coherent energy and the speed and efficiency with which coherent energy can be mobilised (see Ho, 1995). Thermodynamically, then, the organism is a dynamically closed system of minimally dissipative coupled cycles feeding off the one-way energy flow, so that the unavoidable dissipation is exported to the environment

The special energy relationship in the organism, therefore, is what enables it to mobilize energy at will, whenever and wherever required and in a perfectly coordinated way. In the ideal, the organism can be conceived as a quantum superposition of coherent activities, with instantaneous (nonlocal) noiseless intercommunication throughout the system. The flow of qi in meridian theory corresponds rather well to the mobilisation of coherent energy. Coherent energy is vital energy, and it is arises because the organism is especially good at capturing energy, storing and mobilising it in a coherent form.

Let us look more closely at the mobilisation of coherent energy. Coherent energy is stored everywhere within the system over the entire range of space-times. Consequently any subtle influence arising anywhere within the system will propagate over the entire system and get amplified to global effects. In other words, the system, by virtue of being full of coherent energy everywhere, will be ultrasensitive to very weak signals. This may be the basis of all forms of subtle energy medicine.

Quantum coherence in living organisms was still firmly rejected by mainstream biologists when I proposed it in 1993 (Ho, 1993). I was in turn inspired by the idea that organisms may store energy as 'coherent excitations', which originated with solid-state physicist Herbert Fröhlich in the 1960s (see Frohlich, 1980). Later on, quantum physicist turned biophysicist, Fritz Popp, suggested that organisms are quantum coherent photon fields (see Popp et al, 1970; 1992). Today, mainstream scientists including physicist Roger Penrose (1995) have begun to invoke quantum coherence to account for the macroscopic, phase-correlated electrical activities observed by neurophysiologists in widely separated parts of the brain (see Freeman, 1995; Ho, 1997).

I must emphasise that the theory of the organism just presented is firmly based on empirical experimental findings from our own laboratory as well as from established laboratories around the world. Many of the findings are published in scientific journals, but there is little or no satisfactory explanation for them within conventional mainstream biology. I won't have time to describe all the experimental results which have built up a picture of coherence in the organism (see Ho, 1998). Perhaps the most suggestive evidence is our discovery in 1992 that all organisms are liquid crystalline.

What we actually discovered was a novel noninvasive optical imaging technique based on the polarised light microscopy (Ho and Lawrence, 1993; Newton et al, 1995; Ross et al, 1997). It is a technique that earth scientists and other have used for studying mineral crystals, and more recently liquid crystals; in other words, any material with molecular order. But crystals have static order, so how can living, mobile organisms be crystals? Indeed, the imaging technique demonstrates that organisms are so dynamically coherent at the molecular level that they appear to be crystalline (Ho and Saunders, 1994; Ho et al, 1996). That is because light vibrates at 1014Hz, much faster than the molecules can move coherently together, which is at most 1010 Hz. So long as the motions among the molecules in the cells and tissues are sufficiently coherent, they will appear to be statically ordered, or crystalline, to the light passing through. This is analogous to the ability of a very fast film to capture the image of a moving object as a sharply focussed ‘still’ picture. This imaging technique is telling us that the living organism is coherent beyond our wildest dreams, with dynamic order that extends from the molecular to the macroscopic.

There is a dynamic, liquid crystalline continuum of connective tissues and extracellular matrix linking directly into the equally liquid crystalline cytoplasm in the interior of every single cell in the body (see Ho, 1997; Ho, 1998; Ho and Knight, 1998, and references therein). Liquid crystallinity gives organisms their characteristic flexibility, exquisite sensitivity and responsiveness, thus optimizing the rapid, noiseless intercommunication that enables the organism to function as a coherent, coordinated whole. In addition, the liquid crystalline continuum provides subtle electrical interconnections which are sensitive to changes in pressure, pH and other physicochemical conditions; in other words, it is also able to register ‘tissue memory’. Thus, the liquid crystalline continuum possesses all the qualities of a ‘body consciousness’ that may indeed be sensitive to all forms of subtle energy medicines including acupuncture.

The connective tissues of our body include the skin, bones, tendons, ligaments, cartilege, various membranes covering major organs and linings of internal spaces. We tend to see them as serving purely mechanical functions to keep the body in shape, or to act as packing material. Actually, connective tissues may also be largely responsible for the rapid intercommunication that enables our body to function effectively as a coherent whole, and are therefore central to our health and well-being.

The clue to the intercommunication function of connective tissues lies in the properties of collagen, which makes up 70% or more of all the proteins of the connective tissues. Connective tissues, in turn form the bulk of the body of most multicellular animals. Collagen is therefore the most abundant protein in the animal kingdom.

There are many kinds of collagens - all sharing a general repeating sequence of the tripeptide, (X-Y-glycine), where X and Y are usually proline or hydroxyproline (reviewed in Ho and Knight, 1998; Haffegee, 1999; Zhou, 1999). They also share a molecular structure in which three polypeptide chains are wound around one another in a triple-helix (rather like an electric flex) with the compact amino acid glycine in the central axis of the helix, while the bulky amino-acids proline and hydroxyproline are near the surface. In the fibrous forms, the triple-helical molecules aggregate head to tail and side-by side into long fibrils, and bundles of fibrils in turn assemble into thicker fibres, and other more complex three-dimensional liquid crystalline structures. Some collagens assemble into sheets constructed from an open, liquid crystalline meshwork of molecules. All these structures are formed by self-assembly, in the sense that they need no specific 'instructions' other than certain conditions of pH, ionic strength, temperature and hydration (Zhou et al, 1996; Haffegee, 1999). The process is predominantly driven by hydrophilic interactions due to hydrogen-bonding between water molecules and charged amino-acid side-chains of the protein. Hydrogen bonds is a special kind of chemical bond in which a hydrogen atom is shared between atoms such as oxygen and nitrogen. It is the most important and ubiquitous chemical bond in living systems. If you don't know anything else, you must know the hydrogen bond. A water molecule is made of one oxygen atom and two hydrogen atoms and each of the two hydrogen atoms can make a hydrogen bond with another the oxygen belonging to another water molecule or a protein molecule. And the oxygen atom of the water molecule can accept two other hydrogen atoms in hydrogen-bonds.

But collagens are not just mechanical fibres and composites. Instead, they have dielectric and electrical conductive properties that make them very sensitive to mechanical pressures, pH, and ionic composition and to electromagnetic fields (reviewed in Ho, 1998; Ho and Knight, 1998; in particular, Zhou, 1999). The electrical properties depend, to a large extent, on the bound water molecules in and around the collagen triple-helix. X-ray diffraction studies reveal a cylinder of water surrounding the triple-helix which is hydrogen-bonded to the hydroxyproline side-chains. Nuclear magnetic resonance studies and Fourier Transform InfraRed (FTIR) spectroscopy have both provided evidence of three populations of water molecules associated with collagen. These are interstitial water, very tightly bound within the triple-helix of the collagen molecule, and strongly interacting with the peptide bonds of the polypeptide chains; bound water, corresponding to the more loosely structured water-cylinder on the surface of the triple helix; and so called free water filling the spaces between the fibrils and between fibres. Typically, there is a layer of water some 4 to 5 molecules deep separating neighbouring triple-helices. This biological water is integral to the liquid crystallinity of collagens (Zhou et al, 1999) and other composites such as the extracellular matrix, the cell membrane and the 'cytoplasm'.

The existence of the ordered network of water molecules, connected by hydrogen bonds, and interspersed within the protein fibrillar matrix of the collagens is especially signicant, as it is expected to support rapid jump conduction of protons, ie, hydrogen atoms without its electron, which constitute positive electric charges. This jump conduction is a kind of semi-conduction and is much faster than ordinary electrical conduction or conduction through nerve fibres. That is because it does not actually require any net movement of the charged particle itself. It is passed rapidly down a line of relatively static, hydrogen-bonded water molecules.

Jump conduction of protons in collagen has been confirmed by dielectric measurements. The conductivity of collagen increases strongly with the amount of water absorbed (from 0.1 to 0.3g/g collagen), in accordance with the power-law relation,

s(f) = XfY

where f is the water content, andX and Y are constants. The value of Y is found to be 5.1 to 5.4, and is a function of the collagen fibrillar structure. These results suggest that continuous chains of ordered water molecules join neighbouring ion-generating sites enabling proton jumps to occur. The high value of the exponential suggests that up to 5 or 6 neighbours may be involved in the jump conduction. Based on these findings, it is estimated that conductivity along the collagen fibres is at least one-hundred time that across the fibre.

A major factor contributing to the efficiency of intercommunication is the structured, oriented nature of collagen liquid crystalline fibres. Each connective tissue has its characteristic orientation of fibrous structures which are clearly related to the mechanical stresses and strains to which the tissue is subject. This same orientation may also be crucial for intercommunication.

Aligned collagen fibres in connective tissues provide oriented channels for electrical intercommunication, and are strongly reminiscent of acupuncture meridians in traditional Chinese medicine. As collagen fibres are expected to conduct (positive) electricity preferentially along the fibres due to the bound water, which are predominantly oriented along the fibre axis, it follows that these conduction paths may correspond to acupuncture meridians. By contrast, acupoints typically exhibit 10 to 100-fold lower electrical resistances compared with the surrounding skin, and may therefore correspond to singularities or gaps between collagen fibres, or, where collagen fibres are oriented at right angles to the dermal layer. The actual conducting channels may bear a more subtle relationship to the orientation of the collagen fibres, as conductivity depends predominantly on the layer(s) of bound water on the surface of the collagen molecules rather than the collagens themselves. So-called free water may also take part in proton conduction as the result of induced polarization, particularly as water molecules naturally form hydrogen-bonded networks. This would be consistent with the observed increase in conductivity of collagen as hydration increases to a level well beyond the bound water fraction, around 0.15g/g; and with the fact that the normal hydration level of tendon is about 65%.

The hydrogen-bonded water network of the connective tissues is actually linked to ordered hydrogen-bonded water in the ion-channels of the cell membrane that allow inorganic ions to pass in and out of the cell. There is thus a direct electrical link between distant signals and the intracellular matrix of every single cell in the body, leading to physiological changes inside the cells, including all nerve cells. This electrical channel of intercommunication is in addition to and coupled with the mechanical tensegrity interactionsbetween the connective tissues and the intracellular matrix of every single cell, a continuum that always changes as a whole. Any mechanical deformations of the protein-bound water network will automatically result in electrical disturbances and conversely, electrical disturbances will result in mechanical effects.

As mentioned earlier, proton jump-conduction is a form of semi-conduction in condensed matter and much faster than conduction of electrical signals by the nerves. Thus the ‘ground substance’ of the entire body may provide a much better intercommunication system than the nervous system. Indeed, it is possible that one of the functions of the nervous system is to slow down intercommunication through the ground substance. Lower animals which do not have a nervous system are nonetheless sensitive. At the other end of the evolutionary scale, note the alarming speed with which a hypersensitive response occurs in human beings, or how rapidly they can respond to an emergency. There is no doubt that a body consciousness exists prior to the ‘brain’ consciousness associated with the nervous system.

I have argued that a body consciousness possessing all the hallmarks of consciousness - sentience, intercommunication and memory - is distributed throughout the entire body. Brain consciousness associated with the nervous system is embedded in body consciousness and is coupled to it (Ho, 1997; 1998).

Under normal, healthy conditions, body and brain consciousness mutually inform and condition each other. The unity of our conscious experience and our state of health depends on the complete coherence of brain and body.

Traditional Chinese medicine based on the acupuncture meridian system places the emphasis of health on the coherence of body functions which harmonizes brain to body. This makes perfect sense if one recognizes the brain as part of the body. Western medicine, by contrast, has yet no concept of the whole, and is based, at the very outset, on a Cartesian divide between mind and brain, and brain and body. Because there is no concept of the organism as a whole, there is, in effect, no theory of health, only an infinite number of disease models, each based on the supposed defect of a single molecular species. There is an urgent need to develop a theory of health for proper delivery of healthcare in the next millenium.

Link: http://www.i-sis.org.uk/acupunc.php
 
Keyhole said:
Traditional Chinese medicine based on the acupuncture meridian system places the emphasis of health on the coherence of body functions which harmonizes brain to body.

Coherence is a very interesting concept and it is exciting to see that our entire body may (or may not) be coherent from a higher energy point of view. In this regard, I think that they will find very interesting things if they study Reiki. Other therapies like Rolfing massage, acupressure and Gua Sha might work on a similar way to acupuncture.

It also reminds me of the polyvagal theory. Although the nervous system might be "slower" to conduct energy than the "connective tissue system", stimulating your vagus nerve also increases coherence in the brain and the body. In any case, everything is connected. Still, it is very interesting to read what these researchers are finding in their labs!
 
Gaby said:
It also reminds me of the polyvagal theory. Although the nervous system might be "slower" to conduct energy than the "connective tissue system", stimulating your vagus nerve also increases coherence in the brain and the body. In any case, everything is connected. Still, it is very interesting to read what these researchers are finding in their labs!

Yes, very interesting indeed! As for everything being connected, here's another example. Not long ago my colleague told me about an epilepsy in dogs, and how there is a research paper about some dogs that stopped having seizures after changing owners.

Now, the etiology of epilepsy is unclear, but even mainstream science accepts that ketogenic diet helps in this regard. But what if there is another element that should be considered as well? Unfortunately, I don't know the name of the research, but intend to find out more about it. In any case, it is said that epileptic seizures are the result of excessive and abnormal nerve cell activity in the cortex of the brain. So what if it isn't only the accumulation of oxidative or other stresses (like an inflammation) in the body, but also a result of an external stress? But not the kind that could be apparent, like the dog being mistreated by their owners. In fact, apparently according to the research dogs weren't mistreated in any way.

But what if there was still a lack of coherence, or there was a "mismatch" of sort? Like what is described in this session? Or perhaps an "informational overload" that led to a seizure? It could explain, at least from the "information theory" point of view, why these dogs were "cured" after changing owners. Just some thoughts that were triggered by the topics presented in this thread. :)
 
As mentioned earlier, proton jump-conduction is a form of semi-conduction in condensed matter and much faster than conduction of electrical signals by the nerves. Thus the ‘ground substance’ of the entire body may provide a much better intercommunication system than the nervous system. Indeed, it is possible that one of the functions of the nervous system is to slow down intercommunication through the ground substance. Lower animals which do not have a nervous system are nonetheless sensitive. At the other end of the evolutionary scale, note the alarming speed with which a hypersensitive response occurs in human beings, or how rapidly they can respond to an emergency. There is no doubt that a body consciousness exists prior to the ‘brain’ consciousness associated with the nervous system.
it's very interesting that water seems to play this important role for faster communication within the body (if i understand it correctly), since water is related to space/ether, and space is basically what connects all/everthing.
 
Below is a detailed examination of the relationship between the protein structures and water. It is pretty technical, so it will take a few reads to take anything from it I think. It is basically proposing a unified theory for how water binds to macromolecular structures so that it can carry/transfer energy/information.

IMO, the main take home here is that the authors claims that the ability of a structure to successfully bind with water is partly controlled by the energy status of the cell. This is in line with Dr Kruse's ideas that the cellular redox potential determines whether the cell water can become structured cell water or not. It seems that ATP's effect on protein structure is not fully understood, but possibly contributes to its ability to bind with water. So it comes back to increasing energy in the system (via ATP and optimal redox chemistry).

The Importance of Cell Water

Prof. Martin Chaplin presents a new theory on the structure of water in the cell that switches between low-density and high-density clusters

Although we understand much of what goes on inside cells at a molecular level, we don't know how all the molecules can work together as a whole. Much useful biochemistry has been discovered using dilute preparations from homogenised dead cells, but living cells are very different, and contain more concentrated solutes and more organised proteins. Indeed, test tube experiments may mislead us, and it should come as no surprise to find that living cells possess characteristics that are very much more than the sum of their parts.

The study of the live cell is fraught with difficulty, as most procedures change it from its native state. The key to understanding the cell comes from acknowledging the one constituent that has often been ignored: water. The significance of water for the cell becomes clear when we seek to solve big puzzles, such as 'How are potassium ions able to maintain a high concentration inside cells whereas sodium ions are found mainly outside?' and 'How do cells remain functional even when large holes are made in their surface membranes?'

There are at least four views as to how the water inside the cell affects its function:
  • The water mostly acts as an uncomplicated environment for the cellular processes, which are determined by the structure of the macromolecules only. Although this view seems the one most promoted in current textbooks by default, it is rapidly losing favour due to its inability to explain natural processes.
  • The water forms polarised multi-layers over extended protein surfaces, as proposed for many years by Gilbert Ling [1]. There is much experimental support for the foundations of this theory but little experimental support for the required structural changes in the proteins or the involvement of extended protein surfaces, as proposed.
  • The water is involved in intracellular changes between 'sol' and 'gel' states as more recently promoted by Gerald Pollack [2]. This is an interesting and useful idea but without a clear molecular mechanism.
  • The water actively changes the density of its hydrogen bonded structuring to enable diverse intracellular processes, in a manner compatible with the basic ideas of both Gilbert Ling and Gerald Pollack.
The theory that I shall describe in this article (which I presented at the Gordon Research Conference on Interfacial Water and Cell Biology in June 2004) belongs to the fourth, new category. I propose that changes in the density and clustering of intracellular water are modulated by the mobility of key proteins, which in turn are controlled by the energy status and ionic content of the cell.

The nature of water

Water possesses many properties that seem strange, or anomalous [3]. Some of these, such as its high melting and boiling points can be simply explained as due to water's hydrogen bonded clustering. Over the last 10 years, a broad range of evidence has accumulated concerning a two-state structuring within liquid water, which can explain many of the remaining anomalies [4, 5]. This theory involves the presence in liquid water, of clusters with a lower density comparable with that of ice. The water molecules in such clusters flicker between partners as their hydrogen bonds are constantly making and breaking. Over a long time scale, they appear as favoured arrangements. These low-density water clusters do not consist of ice-like crystals, due to their lack of long-range order, but they do contain water molecules linked by hydrogen bonds in an expanded, 4-coordinated tetrahedral arrangement. At the smallest scale, the water may be thought of as an equilibrium between two water tetramers (see Fig. 1): structure A, held closely by non-bonded interactions, forming a more dense structure, and structure B, with molecules held further away and linked by hydrogen bonds to form a less dense structure There is little difference in energy between the structures A and B, so the equilibrium is easily affected by the presence of solutes and surfaces. An increase in temperature or pressure will shift the equilibrium to the left.

Figure 1. Equilibrium between two water tetramers.

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Although the natural structuring in water at ordinary temperatures tends towards the 'collapsed' structure A, the low density structure B can grow to form larger non-crystalline clusters based on dodecahedral (12-sided) water cluster cores, similar to those found in the crystalline 'clathrate hydrates'; as for example, the extensive icosahedral (H2O)280 aggregate built up from tetrahedrally hydrogen-bonded water molecules surrounding a dodecahedron made up of 20 water molecules, the basic clathrate cage (Fig. 2).

Figure 2. Extensive icosahedral (H2O)280 structure of water built up from tetrahedrally hydrogen-bonded water molecules.

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Intracellular water contains lower density water with more potassium ions

The differences in intracellular and extracellular environments of cells is primarily due to the extensive surface area and high intracellular concentration of solutes that promote the low-density clustering of water and restricted diffusion inside cells. The extensive surface of cellular membranes (e.g., each liver cell contain ~100 000 mm2 membrane surface area) favours the formation of low-density water inside cells, as the membrane lipids contain hydrophilic head groups that encourage this organization of the associated interfacial water. Other surfaces attract the water, so stretching the hydrogen-bonded water contained by the confined spaces within the cells.

The difference in ionic concentrations is particularly evident in sodium (Na+; intracellular, 10 mM; extracellular, 150 mM) and potassium (K+; intracellular, 159 mM; extracellular, 4 mM). Na+ ions create more broken hydrogen bonding and prefer a high aqueous density, whereas K+ ions prefer a low-density aqueous environment, as proven by Philippa Wiggins [6]. The differences in intracellular and extracellular distributions of potassium and sodium are due to differences in the affinity of these ions for water. The interactions between water and Na+ are stronger than those between water molecules, which are in turn stronger than those between water and K+ ions, all due to the differences in surface charge density of the ions - that of the smaller Na+ ion being nearly twice that of K+ ions. Ca2+, with an intracellular concentration 0.1 mM and an extracellular concentration of 2.5 mM, has a surface charge density more than twice that of Na+, and has even stronger destructive effects on low-density hydrogen-bonding than Na+ ions.

Other studies confirm the preference of K+ ions for low-density water over Na+ ions. The ions partition according to their preferred aqueous environment; in particular, the K+ ions are preferred within the intracellular environment and naturally accumulate inside the cells at the expense of Na+ ions. This process occurs simply as a result of the water structuring without the help of putative ion-pumps in the cell membrane.

Besides, membrane ion-pumps cannot produce these large differences in ionic composition, simply because the (ATP) energy required far exceeds the energy available to the cell. Also, many studies, as for example, the extensive series carried out by Gilbert Ling, have shown that cells do not need an intact membrane or active energy (ATP) production to maintain the ionic concentration gradients.

The effect of intracellular protein on water structuring

The degree to which the density of cell water is lowered is determined by the solutes and the state of motion of protein. Water has conflicting effects in the mixed environments around proteins due to the variety of amino acids making up their surfaces. Weak interactions between the protein and surface water molecules allow greater protein flexibility. Strong interactions endow the protein with greater stability and solubility.

There is generally an ordered structure in the layer of water molecules immediately surrounding the protein, with both hydrophobic clathrate-like and hydrogen bonded water molecules each helping the other to optimize water's hydrogen bonding network. Protein carboxylate groups are generally surrounded by strongly hydrogen-bonded water whereas the water surrounding the basic groups arginine, histidine and lysine tends towards a more-open clathrate structuring. The formation of partial clathrate cages over hydrophobic areas maximizes non-bonded interactions between the water and the protein without loss of hydrogen bonds between the water molecules whereas carboxylate groups usually only fit a collapsed water structure (see below) creating a reactive fluid zone.

The rotation of the proteins will cause changes in the water structuring outside this closest hydration shell. At the breaking surface, hydrogen bonds are ruptured, creating a zone of higher density water. Protein rotation thus creates a surrounding high-density water zone with many broken hydrogen bonds.

The importance of protein carboxylate groups

Protein has two acidic amino acids, aspartate and glutamate, with carboxylate (-CO2-) side chains. Normally, aqueous hydrogen bonding to these carboxylate oxygen atoms both attracts water molecules causing a localised high density water clustering and reduces the acidity of the carboxylic acids. Otherwise, when the surrounding water molecules prefer to hydrogen bond to themselves as with the formation of a clathrate cage, the acidity of the carboxylate groups is increased. It is found that Na+ ions prefer binding to the weaker carboxylic acids whereas K+ ions prefer the stronger acids [1].

Na+ and K+ ions also behave differently when close to the carboxylate groups; K+ ions have a preference for forming ion pairs, where there is direct contact between the K+ and carboxylate ions, whereas Na+ ions form solvent separated pairings where water molecules lie between the Na+ and carboxylate ions, forming strengthened hydrogen bonds to the carboxylate groups [7]. This is due to the Na+ ions holding on to their water more strongly. The K+ ions prefer to be within a clathrate water cage and this preference both reinforces its direct ion pairing to the carboxylate group and discourages aqueous hydrogen bonding to the associated carboxylate groups.

The direct association of K+ ions with the aspartate and glutamate groups in proteins is the central theme of Ling's fixed charge hypothesis where evidence for the molecular mechanism for the association includes (1) the low intracellular electrical conductance, (2) the strongly reduced mobility of intracellular K+ ions, (3) the one to one stoichiometric absorption of K+ ions to the carboxylate groups and (4) identification of the K+ ion absorption sites as the aspartate and glutamate side chains of the intracellular proteins.

The importance of protein mobility

Actin is a highly conserved and widespread eukaryotic protein (42-43 kDa) responsible for many functions in cells. Non-muscle cells contain actin in amounts 5-10% of all protein, whereas muscle cells contain about 20%. Actin is converted between a freely rotating monomer molecule (G-actin; about 4 - 6 nm diameter) and a static right-handed double helical polymer protein filament (F-actin; up to several microns in length) by ATP; a process involving the conversion of an a-helix to a b-turn in one of its structural domains. Each molecule of the freely rotating G-actin can stir a large volume of water, whereas F-actin has a much more ordered structure so creating more order in its surrounding water. The protein fibres trap water, reducing its movement and compensated by greater hydrogen bonding. Also, capillary action stretches the confined water, so ensuring that it is of lower density and hence more highly structured than the bulk water.

All actin molecules contain a conserved negatively charged N-terminus, for example the N-acetyl-aspartyl-glutamyl-aspartyl-glutamyl sequence in rabbit muscle a-actin. When G-actin polymerises in the cell under the action of ATP to form F-actin, this highly carboxylated antenna is placed on the exposed outer edge of the helix, where it may be additionally used as a binding site for other proteins, such as myosin. Tubulin, another intracellular structural protein that forms immobile structures within cells, possesses an even more extensive negatively charged acidic C-terminal conserved antenna of about eight carboxylate groups that serves similar functions.

F-actin's multiply negatively charged N-terminus attracts positively charged cations. Under conditions when the carboxylic acids are weaker, both K+ and Na+ ions may form solvent separated species. This competition results in a preference for Na+ ions and high-density water. However, the natural rotation of the protein will tend to sweep such ions, and their associated water, away. If the protein is prevented from rotating, Na+ ions tend to destroy any low density structuring around carboxylate groups of the protein. However, the intracellular Na+ ion concentration is generally far lower than that of K+ ions, which allows K+ ions to compete successfully for these sites, forming ion pairs and encouraging clathrate formation.

Cooperative conversion of the water structuring

Binding of K+ ions by the carboxylate groups lowers the ionic strength of the intracellular solution. As this ionic strength decreases, the acidity of phosphate groups decreases, resulting in the conversion of the intracellular doubly charged HPO42- ions to the singly charged H2PO4- ions, more favourable to low density water clustering. All intracellular phosphate entities will behave similarly. The cooperative effects of the change between static filament formation and freely diffusional protein are summarized in Fig. 3.

Figure 3. A summary of the cooperative effects when mobile proteins such as actin are polymerised,

CW3.jpg


Formation of K+-carboxylate ion pairs leads to the formation of a surrounding clathrate water structuring that further guides icosahedral water structuring (so ensuring maximal hydrogen-bond formation) and informing neighbouring carboxylate groups. This signalling cooperatively reinforces the tetrahedrality of the water structuring found between these groups. The clathrate cage allows rotational mobility (like a ball-and-socket joint), enabling the hydrogen bonding to search out cooperative partners (Fig. 4).

CW4.jpg


Figure 4. This diagram shows the clustering around two K+-carboxylate ion pairs (about 4 nm apart) as may be attached to part of two protein's structures. There are 7-8 shells of water around each surface as is typically found between intracellular proteins. The K+ ions are shown as violet and the water network is shown as linked (i.e. hydrogen bonded) oxygen atoms (shown red) without showing their associated hydrogen atoms. The hydrogen bonding initially forms clathrate cages around the ion pairs, followed by a more extensive icosahedral arrangement. This is then followed by extension of the hydrogen bonding along 'rays' connecting the neighbouring sites. Once these 'rays' link, the hydrogen bonding of each reinforces the other in a cooperative manner, so strengthening the linkage and reinforcing the overall low density aqueous environment. As the aqueous clathrate cage possesses a more negative charge on its interior and a more positive charge on the outside, there is a marked polarization in the water molecules that reinforces the hydrogen bonding interactions.

Although the clustering involves a major drop in aqueous mobility, the stronger 4-coordinated bonding compensates this. This theory offers a molecular explanation for Ling's association-induction polarized multilayer model (see "Strong medicine needed in cell biology", this issue). The initial icosahedral size (3 nm diameter), surrounding each ion pair, also equals the water domain size proposed by John Watterson. The tetrahedral structuring possesses five-fold symmetry, which prevents easy freezing in line with the pronounced supercooling found for intracellular water.

Extension of the clathrate network and its associated low density water enables K+ ion binding to all aspartic and glutamic acid groups, not just the key ones within the crucial N-terminal acidic centres. Thus, the sol-gel transition of Pollack (see "Biology of least action", SiS 18) may be interpreted as due to the formation of low density water clustering (the gel state) due to clathrate clustering around K+-carboxylate ion pairs.

In the presence of raised levels of Na+ and/or Ca2+ ions, as occasionally occurs during some cell functions, these ions will replace some of the bound K+ ions. These newly formed solvent separated Na+ and/or Ca2+ ion pairings destroy the low-density clathrate structures and initiate a cooperative conversion of the associated water towards a denser structuring. - [My note: This is in line with Dr Gerald Pollacks findings that Na+ destroys "Exclusion zone water". This also brings to mind EMF's effect on calcium-gated ion channels in the cell. In short, EMF causes a massive efflux of Ca2+(calcium), which, according to the author, also destroys low density water structuring]

Conclusion

In conclusion, the aqueous information transfer within the cell involves the following:

- Intracellular water favours K+ ions over Na+ ions.
- Freely rotating proteins create zones of higher density water, which tend towards a lower density clustering if the rotation is prevented.
- Static charge-dense intracellular macromolecular structures prefer K+ ion pairs to freely soluble K+ ions.
- Ion paired K+-carboxylate groupings prefer local clathrate water structuring.
- Clathrate water prefers local low density water structuring.
- Low density water structuring can reinforce the low-density character of neighbouring site water structuring.
- Na+ and Ca2+ ions can destroy the low density structuring in a cooperative manner.


link: http://www.i-sis.org.uk/TIOCW.php
 
Everyone knows that because the organism is an open system, it does not actually violate the second law, because the environment provides raw materials and useful energy and becomes more disordered as organisation is built up and maintained in the system, and entropy exported out of it.

This seems to describe the STS life form, that takes in energy to sustain itself at the cost of increased disorder for the world outside the life form. I wonder if the STO life form does not increase disorder for the outside world, thereby violating the second law of thermodynamics? I wonder if the second law of thermodynamics is an STS law and does not apply to STO?
 
Hi Keyhole,

Thanks for posting on one of my favourite subjects :)

Keyhole said:
Supporting paper for the previous lecture ... discussing the fascia network and acupuncture meridian system.

Further to the role of the fascia, have you come across Bowen Therapy?

'...gentle rolling motions along the muscles, tendons, and fascia. The therapy's distinctive features are the minimal nature of the physical intervention'

'Bowen had no formal medical training and described his approach as a "gift from God". He died as an unlicensed practitioner of manual therapy...several years before his death, a public inquiry (government of Victoria, Australia) reported that Bowen treated an estimated 13,000 patients per year, with an 80 percent success rate in symptoms that were associated with a wide range of conditions.'


Source- https://en.wikipedia.org/wiki/Bowen_technique

Keyhole said:
..It fits in nicely with the electric universe and information theory.

And regarding EUt, have you by chance read Michael Talbot's 'The Holographic Universe'?

https://www.amazon.com/Holographic-Universe-Revolutionary-Theory-Reality/dp/0062014102

http://www.crystalinks.com/holographic.html

http://www.electricuniverse.info/Electric_Universe_theory

They dovetail very nicely in my opinion.

mrtn said:
it's very interesting that water seems to play this important role for faster communication within the body (if i understand it correctly), since water is related to space/ether, and space is basically what connects all/everthing.

Dr. Masuru Emoto has also demonstrated some fascinating relationships between water and 'resonance'.

http://www.masaru-emoto.net/english/water-crystal.html

With a background in electrical power generation, I've experienced physical interaction with very high EMF zones (present in restricted areas :halo:) which has led me to contemplate the capacity of the, calcium rich, skeletal structure to also act as the basis of a tranceiving antennae?

gnosisxsophia said:
In the course of personal observation I'm starting to suspect a correlation between the pituitary, pineal & spinal cords own 'shepherds crook configuration' - and obviously taking into consideration Calcium's exceptional conductivity and frequency Tx / Rx abilities. This appears to me at least a plausible symbol (in physical terms) of the body's ability to not only receive 'waves' via interaction with the skeletal structure and then tranduce via the endocrine- but also to transmit in the opposite direction?

Something along the lines of a 'Quantum energy generator'?

Cheers
 
I've been enjoying Oschman's video presentation. What a great quote he uses for his first powerpoint slide!
 
gnosisxsophia said:
...
Further to the role of the fascia, have you come across Bowen Therapy?

I first learned of Bowen Therapy on Dr. Mercola's site years ago. This therapy is also know as NST, NeuroStructural integration technique, pointing to its focus on the body's structural components (i.e. Oschman's "connective tissue matrix", which includes the fascia, etc. ).

A client I sent to an NST practitioner had remarkable relief from years of chronic pain stemming from back surgeries and childhood sexual abuse. I then went for a session and had instant relief from chronic sinusitis.

Here's a comprehensive article I'd recommend:
_http://www.mercola.com/nst/neurostructural-integration-technique.htm
 
Interesting, zak.

Neuronal excitability seems to be one of the primary issues with the migraines. In fact, over excitability is characteristic of most pathology.

On the topic of "ion channels", it depends how you view an ion channel's function. If you go with the mainstream view, then the opening of ion channels allows an outflux of potassium from the cell which is accompanied by calcium ion (etc) signalling inside the cell to trigger excitation. From what I understand, the idea is that by targeting these ion channels, you can help to regulate the excitation. So from this perspective, I can see why you have pointed to potassium supplementation.

However, the above only applies if we have faith in the mainstream model of "cell membranes" being impermeable to solutes, which forms the requirement for these ion channels to 'pump' ions across so as the allow them to enter or exit the cell

To turn the whole thing upside down, we can enter into Gilbert Ling's territory: the 'association-induction hypothesis' shows that "potassium ion channels" play a minor role in ion distribution and cell excitation (perhaps more of a supportive role in the process.

It shows that cells that are low in ATP extrude potassium ions naturally and facilitate the entry of calcium/sodium ions... and no pumps or ion channels are required for this. When potassium has left the cell, the cell is in an excited state. Normally when the cell activity has been accomplished (in this case neuronal transmission) and ATP has been replenished, the cell can return to its "rested" and non-excited state, whereby it allows potassium to enter once more.

However, in the case of ATP depletion and lack of ability to produce proper amounts of ATP, the cell remains in a permanently excited state. In the end, the permanent excitatory activity eventually leads to cell death.

So what I am trying to say is, the way you view migraines depends on the framework that you work from. The majority will work from the mainstream (and I believe disproven) framework focusing on ion channels and impermeable membranes. Whereas if we go from Ling's somewhat well established hypothesis (that makes a lot more sense!), it places more emphasis on the energetic status of the cell. In other words, it emphasises that adequate levels of ATP in the cell are required for it to be in a rested and healthy state.

Hi Keyhole, for now i prefer to respond at your post in your thread here than the infrabed one.(Because in think in digging a little in this way, there 're some dots can be find to catch more "the infrabed".)
You brought an important point about Ling's Association-Induction Hypothesis (AIH) and the standart view point
membrane (pump) theory (MT).

I read Mae-Wan Ho and G.Pollack here and there, and i see that you are already on this way, and that you have some good threads (https://cassiopaea.org/forum/index.php/topic,44298.0.html and https://cassiopaea.org/forum/index.php/topic,44064.0.html...), so i was wondering, if you know the works of Vladimir Matveev, before to find that in the past he posted two times in the forum, i read one article of his works with L.Jaeken where as Ho and Pollack they keep on going with Ling'stuff and a little step more.

Some excerpts of the article of Jaeken and Matveev about "Coherent Behavior and the Bound State of Water and K+ Imply Another Model of Bioenergetics: Negative Entropy Instead of High-energy Bonds":

The group of Cosic [83, 84] further elaborated this idea in their ‘Resonance Recognition Model’. They used a calculation to transform an amino acid sequence into a frequency pattern. When this was done for proteins exerting similar functions, a typical common frequency was always found, indicative of that function, but also found in the frequency spectrum of their targets. It follows that it is characteristic of their reciprocal attraction and recognition by resonance. The frequency range for protein in-teractions is 1013 to 1015Hz (equivalent to the near-infrared, visible and near-UV spectra). Common frequen-cies were calculated and also measured, and the measurements were found to match the calculations. The authors concluded that the specificity of protein interactions is based on resonant electromagnetic energy transfer at a frequency specific for each kind of interaction or function.
The question to be addressed now is whether or not his energy model is complete? According to Ling it is.
However, in his AIH almost nothing is said about globular proteins, although he agrees that they occur in vivo.
Does their existence makes a difference for cell energetics? We think it does, although only in a secondary way. In our view
thermodynamics of globular proteins can be described by the green line in Fig. (1); and this line has to be added to the
view presented by Ling. Our view is based on Matveev’s recent ‘native aggregation hypothesis’ (NAH).

Schrödinger’s idea that ‘life feeds on negative entropy’ [17] could not find its place in MT because, according to MT, the media on both sides of the plasma membrane do not differ in entropy (ions and water are thought to be free on
both sides). MT has therefore been the greatest obstacle to the spread of physical ideas and methods in cell physiology.
As a result, there is a huge gap between cell physiology and both physics and chemistry (especially colloid chemistry). It
is clear that the living cell is a multiphase system with many interfaces including the surfaces of proteins, protein com-plexes, and different supra-molecular structures. For most biologists the term ‘colloid’ is associated with the early 20th
century. However, during the past two decades, colloid chemistry has developed a great deal. The knowledge obtained must now be used to solve problems of cell physiology. Biologists, who are working with colloidal systems (cells and cell models) but possibly not realizing it, may draw erroneous conclusions if they lack knowledge of physical and colloid chemistry. What seems to have been proven may be a serious mistake. It is necessary to combine the efforts of scientists from various specialties. Ling’s AIH is a good springboard for physicists who are interested in biology. But even more, everybody working in biosciences should have knowledge of Ling’s AIH, Pollack’s GSH and the coherent behavior of cells. An alternative view of such broad extent and importance including a different view of cellular energetic, expanded slightly by the present study,
should not be missing from general textbooks and basic university courses.
So i am wondering (again!) with the dots that you already have, , if YOU WANT (of course !!!) to connect all those works with in mind the infrabed thread.
 
I read Mae-Wan Ho and G.Pollack here and there, and i see that you are already on this way, and that you have some good threads (https://cassiopaea.org/forum/index.php/topic,44298.0.html and https://cassiopaea.org/forum/index.php/topic,44064.0.html...), so i was wondering, if you know the works of Vladimir Matveev, before to find that in the past he posted two times in the forum, i read one article of his works with L.Jaeken where as Ho and Pollack they keep on going with Ling'stuff and a little step more.

Wow! I missed Matveev's introduction! To answer your question - yes, I am a big fan of Matveevs work. A couple of his papers really helped me understand Ling's work and put some things in context. Similarly, Pollack and Ho were also a great introduction, because Ling's actual writing is very difficult to read for someone with no formal training in biology or biochemistry IMO.

The question to be addressed now is whether or not his energy model is complete? According to Ling it is.
However, in his AIH almost nothing is said about globular proteins, although he agrees that they occur in vivo.
Does their existence makes a difference for cell energetics? We think it does, although only in a secondary way. In our view
thermodynamics of globular proteins can be described by the green line in Fig. (1); and this line has to be added to the
view presented by Ling. Our view is based on Matveev’s recent ‘native aggregation hypothesis’ (NAH).

Yeah a lot of the water researchers are coming out with similar conclusions. Namely that Ling's hypothesis can act as a foundation, but is incomplete in many ways. This is to be expected though, since the subject has been entirely neglected by the scientific community for such a long time. Martin Chaplin has a good chapter on this topic called "Information Exchange within Intracellular Water" [chapter 5] in this book (free PDF link).

The group of Cosic [83, 84] further elaborated this idea in their ‘Resonance Recognition Model’. They used a calculation to transform an amino acid sequence into a frequency pattern. When this was done for proteins exerting similar functions, a typical common frequency was always found, indicative of that function, but also found in the frequency spectrum of their targets. It follows that it is characteristic of their reciprocal attraction and recognition by resonance. The frequency range for protein in-teractions is 1013 to 1015Hz (equivalent to the near-infrared, visible and near-UV spectra). Common frequen-cies were calculated and also measured, and the measurements were found to match the calculations. The authors concluded that the specificity of protein interactions is based on resonant electromagnetic energy transfer at a frequency specific for each kind of interaction or function.

A good book for a very brief overview is called "Energy Medicine" by James Oschman. There is also another you may be interested in, and its called "Light in Shaping Life" by Roeland Van Wijk. The latter focuses primarily on the electromagnetic emissions such as ultra-weak biophotons from cells as possible modes of communication.

The concept of physiological coherence is really quite fascinating. Mae-wan Ho has spoken at length about the topic and how it may relate to disease.

The following article provides some information also:

Evidence for the existence of coherent excitations in biological systems came from the study of biophotons (see Popp et al, 1981; Popp, 1986). Practically all organisms emit light at a steady rate from a few photons per cell per day to several photons per organism per second. An increasing number of observations within the past 15 years from different laboratories all over the world suggest that biophotons are emitted from a coherent photon field within the living systems. Organisms are thus emitters and most probably, also receivers of coherent electromagnetic signals which may be essential for their functioning (see next Section).

The nature of the light emitted from living organisms is best studied after a brief exposure to weak illumination. It has been found, without exception that the the re-emitted light from living tissues follows, not an exponential decay curve as characteristic of non-coherent light, but a hyperbolic decay function which is exhibited only by coherent light (see Fig. 1). This unusual behaviour can be intuitively understood as follows. In a system consisting of non-interacting molecules emitting at random, the energy of the emitted photons are lost completely to the outside or converted into heat, which is the ultimate non-coherent energy. If the molecules are emitting coherently, however, the energy of the emitted photons are not completely lost to the outside. Instead, part of it is coherently reabsorbed by the system. The consequence is that the decay is very much delayed, and follows characteristically a hyperbolic curve with a long tail. This result can be derived rigorously from both classical and quantum mechanical considerations (Popp, 1986). A coherent system stabilizes its frequencies during decay whereas a noncoherent system always suffers a shift in frequencies. That, and the capability to reabsorb emitted energy account for the stability of coherent states.
[..]
A first experiment of this kind was performed by Schamhart and van Wijk (1987). They exposed suspensions of cultivated rat liver and rat hepatoma cell lines H35 and HTC for some seconds to white-light from a 150W tungsten lamp and registered the re-emitted light afterwards. The decay curves are, as usual, hyperbolic rather than exponential. On altering the number of cells in the suspension, the found that normal cells exhibit decreasing light re-emission with increasing cell density, whereas tumour cells show a highly nonlinear increase with increasing cell density (see Fig. 3). If there were no long-range interactions between the cells, the intensity of re-emitted photons would increase linearly with increasing number of cells, corrected by a term for self-absorption within the population. Neither the nonlinear increase of re-emission intensity from tumour cells nor the significant decrease of re-emission from normal cells could be explained unless there are long-range interactions between the cells, which are furthermore, correlated with their differing social behaviour, the tendency of tumour cells to disaggregation as opposed to the tendency of normal cells to aggregate.

These phenomena can be interpreted in terms of Dicke's (1954) theory of photon-emission from an ensemble of emitters. He showed that photon emission tends to bifurcate into the two branches of superradiance and subradiance as soon as the wavelength of the emitted light is large compared to the distances between the emitters which are also absorbers. Superradiance is the increase of emission intensity concomittant with a shortening of the relaxation time. The opposite branch describes the regime of subradiance where emission intensity decreases with a more and more prolonged decay time, corresponding to photon storage within the system.

In terms of Dicke's theory, normal cells have a greater capacity for subradiance the closer they are together, while the malignancy of tumour cells is associated with the opposite behaviour, that is, the loss of subradiance. This suggests that long-range interaction is based on the coherence of the subradiance regime, with the coherence volume extending over the entire cell population. By changing the degree of coherence the cells can control and regulate their social activities. According to this model, tumour cells, unlike normal cells, seem unable to communicate. This may account for the repulsive forces that are responsible for metastasis in the malignant cells as opposed to the attractive forces responsible for population formation in normal hepatocytes (for further details see Nagl and Popp, 1987).

There is also Guenter Albrecht-Buhler who has done extensive work on cell intelligence. Here is part of the introduction on his website:

My research for the past 30 years or so was devoted to examine whether cells have such signal integration and control center(s). The results suggest that mammalian cells, indeed, posess intelligence. The experimental basis for this conclusion is presented in the following web pages.
The most significant experimental results are:
1. The motile machinery of cells contains subdomains ('microplasts') that can be isolated from the cell and then are capable of autonomous movements. Yet, inside the cell they do not exercise their ability. The situation is comparable to a person's muscles that are capable of contraction outside a person's body, but do not contract at will once they are part of the person, suggesting that they are subject to a control center.
2. The cell as a whole is capable of immensely complex migration patterns for which their genome cannot contain a detailed program as they are responses to unforseeable encounters ( Cell movement is not random.. ).
3. Cells can 'see', i.e. they can map the directions of near-infrared light sources in their environment and direct their movements toward them. No such 'vision' is possible without a very sophisticated signal processing system ('cell brain') that is linked to the movement control of the cell. (The larger their light scattering, the larger the distance from which aggregating cells came together. )
In addition there is the supporting theoretical consideration that the hiterto completely unexplained complex structure of centrioles is predicted in every detail if one asks what structure a cellular 'eye' should have.

In relation to the "infrabed" stuff, it seems like the utilisation of different light frequencies acts on multiple levels. I tend toward thinking that the fundamental mode of action of the light is much 'deeper' than than simply acting on a tissue/cellular level to reduce inflammation. The reduction of inflammation and the increase in respiration seem to be outward manifestations of a more fundamental exchange of information which facilitates an increase in communication and an "ordering" effect to reduce entropy within the system of the cell.

Perhaps exogenous NIR light acts as a substitute for the natural NIR that cells usually generate for communication & coordination purposes, yet when they become sick they are unable to do so due to faulty mechanics somewhere down the line. So in this case, by supplementing with light you are perhaps "recharging" or whatever. I believe this actually is the case with UV light after reading Van Wijk and research referenced by Jack Kruse. Living organisms seem to need to top up on UV light to replace what is lost via photon emission. Aside from that, when you begin to understand the effect of UV light on hormones and amino acids (amongst other things), it is clear that UV light should probably be supplemented with as well.

Pollack has shown that water can act as an electron sink, while continually pump protons with ZERO energy supply other than infra-red and some UV frequencies of light. Further, Ho and colleagues also present evidence support the idea that structured/ "coherent domains" of water are capable of providing activation energy for molecular processes.

It is really easy to geek-out on this stuff and lose sight of the bigger picture for me though. Ultimately, not every average person needs to be aware of the research in these field to be healthy. It seems quite simple in many ways... get lots of sunlight, optimise mitochondrial function by identifying and correcting the imbalance/toxicity, eating the right kinds of foods, decrease miscommunication between cells by crappy lifestyle choices like artificial light exposure at night time. Then of course the emotional side of things, like Gabor Mate's work. Obviously, the above is nuanced in multiple ways, but those seem to be some pretty basic rules.

edit: spellings and a deleted paragraph
 
While it's not directly related to the Electric Universe, some work by Sungchul Ji (Sayer Ji's dad) on information and wave dynamics and their relationship to DNA and cell structure seems like it might still be relevant:

http://www.conformon.net

The site isn't the most user-friendly -- it looks like someone (maybe a grad student?) was asked to throw it together, and there are multiple links which lead to the same pages and some pages which are still blank. Nevertheless, there appears to be some interesting stuff there for anyone who might be interested in taking a look.
 
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