Scientists identify natural SARS-CoV-2 super immunity against 23 variants

[Skyfarmr]

Not sure if this belongs in the CV thread, it's a very busy thread and maybe this belongs there.
But starting a new thread so I could make a suggestion for SOTT article, I'm posting here. I've already posted a link in CV vaccine thread.
Scientists identify natural SARS-CoV-2 super immunity against 23 variants

A team of international scientists has recently identified ultrapotent anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies from convalescent donors.

The antibodies are capable of neutralizing a wide range of SARS-CoV-2 variants even at sub-nanomolar concentrations. In addition, the combinations of these antibodies reduce the risk of generating escape mutants in vitro. The study is published in the journal Science.

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The majority of therapeutic antibodies against SARS-CoV-2 have been designed based on the native spike protein sequence found in the original Wuhan strain of SARS-CoV-2. Thus, novel viral variants with multiple spike protein mutations may likely develop resistance against these antibodies. In this context, studies have shown that antibodies developed in response to currently available COVID-19 vaccines have less efficiency in neutralizing novel variants of concern (VOCs) of SARS-CoV, including B.1.1.7, B.1.351, P1, and B.1.617.2.

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The antibodies were isolated from four convalescent donors infected with the Washington-1 (WA-1) strain of SARS-CoV-2. The spike sequence in the WA-1 strain is similar to the spike sequence in the original Wuhan strain.

The B cells isolated from donor-derived blood samples were sorted for antibody identification. This led to the identification of four potent neutralizing antibodies targeting the spike RBD. These antibodies showed a high affinity for the SARS-CoV-2 spike even at nanomolar concentrations.

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All experimental antibodies exhibited significantly higher potency in neutralizing D614G mutation-containing variants than the WA-1 strain. Further analysis with lentiviral particles pseudotyped with spike variants indicated that the antibodies maintain high potency in neutralizing a diverse set of 10 spike variants.

Importantly, three out of four experimental antibodies showed high efficacy in neutralizing 13 circulating variants of concern/interest of SARS-CoV-2, including B.1.1.7, B.1.351, B.1.427, B.1.429, B.1.526, P.1, P.2, B.1.617.1 and B.1.617.2.

This article reviews the study of convalescent antibodies and basically states that naturally acquired immunity from covid infection IS effective against variants, as well as indicating that vaccine induced antibodies are NOT. It further indicates that the vaccine is creating the situation that is forcing mutations due to the antibodies being too specific for Wuhan strain, while at the same time not being very effective against variants.

so many suspicions confirmed in this article.