Re: Ketogenic Diet - Path To Transformation?
Yeah, It is also interesting that concentrations of plant microRNA can be found in samples of human tissues of Chinese men and women whose main diet was rice. In "Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA", they saw that plant microRNAs in food can regulate how certain human genes are expressed.
When genes code for proteins, they start with the DNA which serves as the template for printing out what is called as messenger RNA (mRNA) which will hold the instructions to make the protein. The microRNAs are tiny pieces of RNA which will attach to protein-making messenger RNA, stopping them from being read and therefore blocking the production of that protein. In short, microRNAs silence the genes they are associated with.
We eat a specific plant’s information. We eat information, we are what we eat. And we will do us a great favor to eat the right information.
It is really very important to give ourselves the chance to effect epigenetic changes through a diet in which humanity thrived for most of its history. We can “control” our genome through our food rather than being controlled by it.
As outstanding as the DNA blueprints stored in the nucleus of the cells are, they still don’t control us as we have seen. Our 50,000,000,000,000 or so cells are coated in fatty cell membranes –which happen to be the interface between the cell and the environment. As biologist Bruce Lipton, PhD explains, information from the environment is transferred to the cell via the cell membrane. The cell membrane (“mem-brain”) monitors the condition of the environment and then sends signals to the genes inside the cell so they can engage cellular mechanisms, which in turn, provide for its survival.
Another important aspect to consider is that our genes live inside the cells, and the nutrients that best protect them from undesirable effects are those who are able to cross the fatty cell membrane that encloses the cell, that is, fat soluble nutrients in animal foods.
The majority of the genome (98%) consists of DNA which was considered to be junk because it didn’t encoded protein. In fact, it is called non-coding DNA. But nowadays it is known that this “junk” DNA is very functional, it acts like genetic switches that regulate when and where genes are expressed.
We are told that a person’s DNA is about 99%-99.5% identical to any other person’s DNA and our differences relies on what is called copy number variants – places in the DNA where the number of copies of a gene can vary from one to many hundreds. Copy number variations took place over a million years ago, others a few thousand years ago. Another way in which we can differ to each other is what is called single nucleotide polymorphisms (SNPs) – a location on the DNA where one of the four nucleotides (whose pairing constitute the base pairs) has been replaced by another. Two people can differ for about 3 million SNPs, which is about 0.1% of their total DNA.
This teensy percentage may account for a lot of differences between each one of us, including the way we tolerate carbohydrates. But experiments which severely restrict carbs point to a consistent shift in our metabolism with little variability. That is, we are hardwired to respond to carbohydrate restriction in a reliable and healthy way. From a genetic point of view, our ability to thrive under a low carb diet is highly conserved as opposed to our ability to tolerate a high carb diet intake. Low carb eating seems to be the normal metabolic state associated with health, which is consistent with the view that throughout most of our human evolution, we thrived under a low carb diet.
obyvatel said:
Yeah, It is also interesting that concentrations of plant microRNA can be found in samples of human tissues of Chinese men and women whose main diet was rice. In "Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA", they saw that plant microRNAs in food can regulate how certain human genes are expressed.
When genes code for proteins, they start with the DNA which serves as the template for printing out what is called as messenger RNA (mRNA) which will hold the instructions to make the protein. The microRNAs are tiny pieces of RNA which will attach to protein-making messenger RNA, stopping them from being read and therefore blocking the production of that protein. In short, microRNAs silence the genes they are associated with.
We eat a specific plant’s information. We eat information, we are what we eat. And we will do us a great favor to eat the right information.
It is really very important to give ourselves the chance to effect epigenetic changes through a diet in which humanity thrived for most of its history. We can “control” our genome through our food rather than being controlled by it.
As outstanding as the DNA blueprints stored in the nucleus of the cells are, they still don’t control us as we have seen. Our 50,000,000,000,000 or so cells are coated in fatty cell membranes –which happen to be the interface between the cell and the environment. As biologist Bruce Lipton, PhD explains, information from the environment is transferred to the cell via the cell membrane. The cell membrane (“mem-brain”) monitors the condition of the environment and then sends signals to the genes inside the cell so they can engage cellular mechanisms, which in turn, provide for its survival.
Another important aspect to consider is that our genes live inside the cells, and the nutrients that best protect them from undesirable effects are those who are able to cross the fatty cell membrane that encloses the cell, that is, fat soluble nutrients in animal foods.
The majority of the genome (98%) consists of DNA which was considered to be junk because it didn’t encoded protein. In fact, it is called non-coding DNA. But nowadays it is known that this “junk” DNA is very functional, it acts like genetic switches that regulate when and where genes are expressed.
We are told that a person’s DNA is about 99%-99.5% identical to any other person’s DNA and our differences relies on what is called copy number variants – places in the DNA where the number of copies of a gene can vary from one to many hundreds. Copy number variations took place over a million years ago, others a few thousand years ago. Another way in which we can differ to each other is what is called single nucleotide polymorphisms (SNPs) – a location on the DNA where one of the four nucleotides (whose pairing constitute the base pairs) has been replaced by another. Two people can differ for about 3 million SNPs, which is about 0.1% of their total DNA.
This teensy percentage may account for a lot of differences between each one of us, including the way we tolerate carbohydrates. But experiments which severely restrict carbs point to a consistent shift in our metabolism with little variability. That is, we are hardwired to respond to carbohydrate restriction in a reliable and healthy way. From a genetic point of view, our ability to thrive under a low carb diet is highly conserved as opposed to our ability to tolerate a high carb diet intake. Low carb eating seems to be the normal metabolic state associated with health, which is consistent with the view that throughout most of our human evolution, we thrived under a low carb diet.
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