I have read about a interesting potent antimicrobial/antifungus/antiviral that maybe can help to fight plague. I am not telling that is works for that because we don't know, but could be good having it in mind. What is fine about it is that is made from a natural fat. This is sell as an supplement, it is called Lauricidin and is a monoglycerid from cocunut oil (lauric acid esters). In order to get the benefices of the anti- microbial/fungus/virus of coconut oil you need to take big quantities because the body only transform a tiny part in the active component monolaurilglycerine.
_http://www.lauricidin.com/
The Million Dollar Question—Does coconut oil have antimicrobial properties?
Coconut oil is one of nature's highest sources of lauric acid. It's reported to contain up to 40-50%. Another natural source of lauric acid is found in mother's milk. So, if you eat coconut oil, are you getting the same immune-boosting effects that mother's milk has proven to give babies? All this discussion about coconut oil having antiviral and antibacterial properties started with the research of Dr. Jon J. Kabara.
The Answer
Unfortunately, these discussions has been started and continue on the Internet by scientists who have not done any original research in this area. Remember what Vladimir Lenin said “A lie told often enough becomes truth”. And so it is with the disinformation found on the Internet on this subject.
Dr. Kabara's research showed that in order to have antimicrobial and immune-boosting properties, the fat in coconut oil and mother's milk has to be broken down into free fatty acids and monoglycerides BEFORE you digest them.
THE FATS IN COCONUT OIL AND MOTHER’S MILK ARE PER SE NOT ANTIMICROBIAL
When babies get mother's milk, the milk contains an enzyme that breaks down the fat into free fatty acids and monoglycerides prior to infant digestion. Coconut oil does not contain this enzyme and therefore little if any monoglycerides are absorbed as such into the body.
Current data shows that if your body does convert virgin coconut oil (VCNO) into monolaurin, you might get less than 1% monolaurin.
Dr. Kabara believes that you need a minimum of 3-9 grams per day of the pure monolaurin (Lauricidin®) to have any health benefits. This is approximately equal to 300 to 900 grams of coconut oil per day. This is a gigantic amount and you'll probably get sick or diarrhea from this much coconut oil.
Using modest amounts of coconut oil to eat, cook or bake is healthy because of its low calories per gram, but the jury is still out on it's role as an effective antiviral when eaten.
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Antiviral Effects
Hierholzer and Kabara (1982) first reported the antiviral activity of the monoglyceride of lauric acid (monolaurin) on viruses that affect humans.. They showed virucidal effects of monolaurin on enveloped RNA and DNA viruses. This work was done at the Center for Disease Control of the U.S. Public Health Service. This study was carried out using selected virus prototypes or recognized representative strains of enveloped human viruses. All these viruses have a lipid membrane. The presence of a lipid membrane on viruses makes them especially vulnerable to lauric acid and its derivative monolaurin. These initial findings from the Center of Disease Control (CDC) have been confirmed by many other investigators.
Research has shown that enveloped viruses are inactivated by added fatty acids and monoglycerides in both human and bovine milk (Isaacs et al 199 1). Others (Isaacs et al 1986, 1990, 1991, 1992; Thormar et al 1987) have confirmed Kabara's original statements concerning the effectiveness of monolaurin.
Some of the viruses inactivated by these lipids are the measles virus, herpes simplex virus (HSV-1 and -2), herpes family members (HIV, hepatitis C, vesicular, stomatitis virus (VSV), visna virus, and cytomegalovirus (CMV). Many of the pathogenic organisms reported to be inactivated by these antimicrobial lipids are those know to be responsible for opportunistic infections in HIV -positive individuals. For example, concurrent infection with cytomegalovirus is recognized as a serious complication for HIV positive individuals (Macallan et al 1993).
Thus, it would appear imperative to investigate the practical aspects and the potential benefit of a nutritional supplement such as monolaurin (Lauricidin®) for microbial infected individuals. Until now few nutritionists in mainstream nutrition community seem to have recognized the added benefit of antimicrobial lipids in the support of infected patients. These antimicrobial fatty acids and their derivatives are essentially nontoxic to man. According to the published research, lauric acid is one of the best "inactivating" fatty acids, and its monoglyceride is even more effective than the fatty acid alone (Kabara 1978, Sands et al 1978, Fletcher et al 1985, Kabara 1985).
It should be emphasized that lauric acid cannot be taken orally because it is severally irritating. Lauricidin® on the other hand, a derivative of lauric acid chemically bonded to glycerin to form monolaurin, can be taken orally without any problem.
Antibacterial Effects
The potentially pathogenic bacteria inactivated by monolaurin include Listeria monocytogenes, Staphylococcus aureus, Streptococcus agalactiae, Groups A, streptococci-gram-positive organisms, and some gram-negative organisms (Vibrio parahaemolyticus and Helicobacter pylori).
Decreased growth of Staphylococcus aureus and decreased production of toxic shock syndrome toxin-l was shown with monolaurin (Holland et al 1994). Monolaurin was 5000 times more inhibitory against Listeria monocytogenes than ethanol (Oh & Marshall 1993). In vitro monolaurin rapidly inactivate Helicobacter pylori. Of greater significance there appears to be very little development of resistance of the organism to the bactericidal effects (Petschow et al 1996) of these natural antimicrobials.
A number of fungi, yeast, and protozoa are also inactivated or killed by monolaurin. The fungi include several species of ringworm (Isaacs et al 1991). The yeast reported to be affected is Candida albicans (Isaacs et al 1991). The protozoan parasite Giardia lamblia is killed by monoglycerides from hydrolyzed human milk (Hemell et al 1986, Reiner et al 1986, Crouch et al 1991, Isaacs et al 1991).
Chlamydia trachomatis is inactivated by monolaurin (Bergsson et al 1998). Hydrogels containing monocaprin/monolaurin are potent in vitro inactivators of sexually transmitted viruses such as HSV-2 and HIV-1 and bacteria such as Neisserian gonorrhea (Thormar 1999).
Monolaurin does not appear to have an adverse effect on desirable gut bacteria, but rather on only potentially pathogenic microorganisms. For example, Isaacs et al (1991) reported no inactivation of the common Esherichiacoli or Salmonella enteritidis by monolaurin, but major inactivation of Hemophilus influenza, Staphylococcus epidermis and Group B gram positive streptococcus.
Microorganisms Inactivated Under Laboratory Conditions
Viruses
HIV or HIV-1, -6
Visna virus
Herpes simplex virus-i (HSV-1 &2)
Vesicular stomatitis virus (VSV)
Measles virus
Rubella virus
Epstein-Barr virus (EBV)
Respiratory syncytial virus
Influenza virus
Dengue virus (Type 1-4)
Leukemia virus
Cytomegalovirus (CMV)
Semliki forest virus
Lymphocytic choriomeningitis
Human papilloma virus (HPV)
Pneumovirus
Bacteria
Gram-positive organisms
Gram-negative organisms
Bacillas anthracis (Anthrax)
Chlamydia pneumonia
Listeria monocytogenes
Neisseria gonorrhoeae
Staphylococcus aureus
Helicobacter pylorus
Groups A, B, F & G streptococci
Mycoplasma pneumonia
Streptococcus agalactiae
Vibrio parahaemolyticus
Mycobacteria
Clostridium perfringens
Yeasts. Fungi and Molds
Aspergillus Niger
Malassezia, species
Saccharomyces cerevisiae
Penicillium citrinum
Ringworm or tinea (Trichophyton)
Candida utilis
A number of protozoa like Giardia lamblia are also inactivated or killed by Lauricidin®
So if that plague virus has a lipidic membrane this could be helpful in addition to other measures as diet, tobacco, etc.
