So I wanted to share my peptide experience here but I would like to preemptively say that I am not an expert by any means, and that everything I’ve done is of/to my own risk and don’t recommend anything without your own substantial research. I am not going to get too deep into what the peptides do at the molecular level because this will become an insanely long post and honestly a quick web search can break it down.
The reason I started “researching” on myself with peptides is because I have a mild form of MCAS where if I begin to exercise I start to develop gastro pressure resulting in gas that I burp and start to mildly break out in hives. This pressure in my abdomen also causes respiratory discomfort and causes me to cough. It only lasts as long as I exercise. I have had a moderate mycotoxin load and I also believe this was the result of a culmination of biotoxins, metals, terrible diet and stress when I was a child, resulting in chronic stress on the body enhanced by EMFs in my opinion.
Long story short, since finding this forum in 2019, I’ve been actively detoxifying my body first with diet then supplementing and eventually the removal of my amalgam fillings. I also exercise almost daily. I’m stating all of this because I believe this is what has caused such a positive effect on myself with the application of these peptides: I was laying a foundation.
So, I intrigued by with a blend of 4 peptides which are known as the KLOW blend which is derived of BPC-157, TB500, GHK-Cu, and KPV.
Here’s a quick Google summary:
“The KLOW peptide blend is a specialized, synergetic mixture of four peptides—
KPV,
Liver-Organ-Protecting-157 (BPC-157),
Thymosin Beta-4 (TB-500), and
GHK-Cu—designed to accelerate healing, reduce inflammation, repair tissues (muscle, gut, skin), and promote cellular rejuvenation. It is used for comprehensive recovery, often aiding with injury healing, gut health, and skin rejuvenation.
Key Functions of the KLOW Peptide Blend:
- Accelerated Tissue Repair & Recovery:Combines BPC-157 and TB-500 to accelerate healing of muscles, tendons, ligaments, and joints, making it highly effective for injury recovery.
- Potent Anti-inflammatory Action: Utilizes KPV to significantly reduce systemic inflammation and address inflammatory conditions.
- Skin, Hair, and Tissue Regeneration:Includes GHK-Cu, which stimulates collagen and elastin production, enhancing skin elasticity, firmness, and overall skin health.
- Gut Health Support: Known to support the restoration of gut mucosal integrity, aiding in the treatment of conditions like leaky gut.
- Metabolic & Energy Enhancement: Some formulations are targeted at enhancing mitochondrial function and regulating metabolism for improved energy and weight management.
The purpose of this was to enhance the repair process of my leaky gut, because despite the years of supplementation and diet, I was still having symptoms of it based off eating and fasting. It was also to experiment general healing. I wanted to seal the gut barrier to stop any further toxins from entering my bloodstream and also potentially calm down the sensitive mast cells with KPV and GHK-Cu, since both have anti-inflammatory and immune modulating properties.
I did this for two months on a 5 days on 2 days off cycle. Then stopped. What I noticed was that my body aches were starting to fade and I was recovering quicker from exercise. My shin splints which would result in stress fractures every time I would try to push myself running, completely stopped (beyond normal soreness) I was able to sprint and then do runs at aggressive paces without excruciating pain. My central spine pain also reduced about 90% and I am able to carry front loads for extended amounts of time again.
Ultimately with KLOW, I was able to reduce the hives and coughing by about 80% I would say. I am satisfied with that result. I am taking two months cycling off to prevent receptor desensitization and antibody buildup, and am debating starting a second cycle.
Moving on, I started to dabble with a brain peptide, and this one is actually one that personally speaking, changed my life and hopefully I continue to reap the benefits i gained from it.
This peptide is called P21. It is a fragment of a complex peptide called Cerebrolysin that is used to heal brain trauma and brain degenerative diseases. P21 intrigued me when I discovered that underground moms were giving this to their autistic children and showing signs of cognitive and social improvement.
Here’s what a quick google search says about it: “P21 peptide, often referring to a synthetic derivative of Brain-Derived Neurotrophic Factor (BDNF) mimetics, is primarily investigated for neuroregeneration, treating Alzheimer’s disease (AD), and enhancing cognitive function. It promotes neurogenesis (nerve growth), reduces Tau protein buildup, and prevents cognitive decline. It is a research compound with no human safety trials to date”
If I could describe myself and how I have felt in my head, it is that I would get sensory overload very easily. If I could put it in technical terms it’s almost as if I was born with a low RAM processor with a crappy hard drive. I have COMT met/met genotype which means that I have a lot of trouble clearing excess dopamine and catecholamines. This would result in so much noise happening inside my head and outside as well. I would constantly feel overwhelmed and this caused me to be a very irritated person, for years. I hated myself for being like this because it’s not how I truly want to feel. It gave me social anxiety and anything that anyone asked of me would feel like a colossal task that took tremendous amount of willpower.
So I decided to try P21 at 50mcg (the typical minimum dose is 100mcg) every other day because my brain is very sensitive to anything and will become oversaturated.
I noticed after about a week that I was able to process multiple important tasks in a short period of time, and by important tasks I mean tending to my son’s needs of changing him, feeding him, playing with him, as well as being present with my wife and genuinely listening to what she was saying, which was crazy, it was always so hard to do, as well as providing for them and working my job.
Here’s where I kind “corrupt” my anecdotal experience however by adding a secondary variable which I genuinely believe enhanced the “positive intentions and emotions” that I had set for myself. I bought a Blushield cube for EMF protection around the 2nd week of P21 usage.
So I have to specify what I felt pre and post Blushield on P21. Pre, I was able to handle a higher load of being present with my family and working my job, but I still felt slight irritation and a building of “stress”. Just more capacity to handle this stress. POST Blushield, it feels like I upgraded my prefrontal cortex’ ram to 32gigs and I am in control of the driver’s seat, 90% of the time. (10% being like intrusive thoughts or something that you have to shoo away).
I feel 90% less self conscious. I literally felt the shift from sympathetic to parasympathetic in my whole body. Most importantly I feel so calm and a load off of my mind that I can “see” my son and wife. I don’t know how to explain this but it’s like time doesn’t matter as much anymore. I don’t need to rush the little guy, or anyone or myself. My resilience against my son’s emotional outbursts (as well as my pregnant wife’s) have become like trying to slap air (you can’t), I just brush it off most of the time now, because of how absurd what I am experiencing is happening right in front of me. I can listen and recall so much of what a person tells me. Most importantly of all, I feel like I can just keep going, I can hold all the bags, bike, kid, on me across a quarter mile and not feel any overwhelming resentment or “woe is me” towards my tired partner who is carrying my second child.
Nicotine’s effects also seem to have enhanced. The focus aspect of it seems to sometimes put me in a mild flow state.
I think one funny thing it has helped me do is become more aware of the garbage that goes on in my head but not be “blasted” by it. Journaling has also felt like it has a bit more “feedback” to it as well.
Overall, I think P21’s properties have enhanced my ability to feel my body, my thoughts and my actions as well as enhanced my observation of other people around me, which is exactly what I desired. It doesn’t turn you into like a god or something but I feel like this is what a normal human being should experience/feel, at least one with a desire to truly live.
Honorable mentions but not that spiritually/mentally impactful (in my opinion):
- Tirzepatide (GLP-2) or Retatrutide (GLP-3), 1.25mg once or twice a week totally helped with fat reduction, glucose control and intermittent fasting. Though Retatrutide didn’t seem to have much of a hunger suppressing effect. I have trained some family at the gym using these and correct diet with incredible non muscle wasting results.
-Tesamorelin and Ipamorelin helped me with strength and recovery as well as cardiovascular endurance in my experience/opinion
So that’s my experience with peptides so far. Again I will say that diet and lifestyle I’m sure plays a huge role in any long term meaningful improvements in health physically and mentally.
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