Could Schizophrenia Be Treated With Nicotine?

http://gizmodo.com/5835898/could-schizophrenia-be-treated-with-nicotine



Smoking is bad for you blah blah we know. But you couldn't really tell that to the 80% of American schizophrenic patients who smoke. The jury is still out on why that number's so high, but could some form of treatment come out of this?

That so many schizophrenics smoke was actually established in a study published in 2006, but the figure has held up since then, even in the face of stiffer tobacco regulations and society in general backing away from it. There are a number of hypotheses that try to explain the link—personality, socioeconomic situation, etc.—but Mark Stewart for the University of Michigan Risk Science Center writes that the patients may be smoking as a means of self-medication.

Schizophrenics often have auditory hallucinations, paranoia, delusions, and disorganized thinking. These symptoms are predominantly caused by the inability of the brains of schizophrenics to differentiate, sort, and focus on the multitude of stimuli that go on around us. Think of being in a busy restaurant. Imagine that instead of being able to block out all the noises, conversations, and movements around you, every single piece of sensory information is as important as the interesting things said by the attractive person sitting across from you. The effects of cigarette smoking and nicotine help schizophrenics through increased selective attention.

This is because, it's theorized, nicotine acts on the flow of dysfunctional flow of dopamine on a schizophrenic's brain. By correcting that, they may feel some relief from their symptoms. Unfortunately, all the adverse side-effects of smoking follow, resulting in higher rates of lung and heart disease.

But the relief a cigarette may provide, at least in the short term, could outweigh the effects of the many anti-psychotic drugs they take. Is there some kind of middle ground then? Nicotine is still a highly addictive substance, but is there a way to use it in treatment? [Risk Science Blog via BoingBoing]

Image Credit: Igor Normann/Shutterstock

Without googling or yet logging into the psych forum to verify... It seems that there is a type of shutting doors that one is attempting to do. Perhaps the science of how nicotine and such is known to dilate the blood vessels applies to what what some may potentially be psychologically needing to do in order to effectively heal. It just makes sense. It is also likened to sleep...

vaio said:

Smoking is bad for you blah blah we know.

[...] Unfortunately, all the adverse side-effects of smoking follow, resulting in higher rates of lung and heart disease.

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Have you read the research shared here about smoking, as well as the articles posted on SOTT about it? You can do a search for "smoking", "nicotine" and "tobacco", and you will find plenty of information. The anti-smoking campaign is basically based on pure lies, when you look at the studies. There isn't a higher rate of lung and heart disease amongst smokers. What IS making people's health go down, though, is all the poisons in the diet, air and water, for example.

So yeah, as far as I know, nicotine has proven to be highly beneficial in the treatment of schizophrenia, and there is no need for a "middle ground", as you put it, because there are no such horrible terrible fatal secondary effects that people have been brainwashed to believe exist (when smoking pure tobacco, that is!)

Ailén said:

Have you read the research shared here about smoking, as well as the articles posted on SOTT about it? You can do a search for "smoking", "nicotine" and "tobacco", and you will find plenty of information. The anti-smoking campaign is basically based on pure lies, when you look at the studies. There isn't a higher rate of lung and heart disease amongst smokers. What IS making people's health go down, though, is all the poisons in the diet, air and water, for example.

Click to expand...

Yup. And even Allan and Lutz, in Life Without Bread, who buy into the anti-smoking lies, quote a study where the smokers who adopted a high fat diet were PROTECTED against cancers to a greater degree than their non-smoking, low-fatters! So not only is the science a fraud, but a healthy diet can go some ways to protecting against imaginary statistics! ;)