Autism

Parasitic behavior manipulation and questions about the nature of "free will" and the autonomy of living beings.

I remembered a documentary about permaculture or organic gardening that introduced a species of wasp that can keep the cabbage white butterfly in check, preventing it from being completely eaten away and leaving something to turn into hearty stews or sauerkraut in the fall.

But above all, I remembered this detail when I was reading the book "GAPS - Gut and Psychology Syndrome: How the Gut and Psyche Influence Each Other. Natural Healing for Autism, ADHD, Dyspraxia, Dyslexia, Depression, and Schizophrenia" by Dr. Natasha Campbell-McBride about the connections and effects of viruses and bacteria in our bodies.

I may not have highlighted this book well enough in the last series of posts here. The book is also available in English. Anyone who is interested in or affected by the diseases listed in the book's title might gain further insights from this book.
Here is a link to a publisher for the German version. The book is certainly also available on Amazon and other platforms.

Based on the connections described in this book and my memory of Parasitic Behavior Manipulation, I explored this topic further with the help of the AI "Gemini." I had the AI summarize the very detailed report again and I think that the following statements also provide a good overall impression.

I find it astonishing how many parallels can be drawn from the hyperdimensional level and fourth density to the bacterial and viral level within us.

Feel free to comment.


Start Content from Gemini ***

Nature is full of astonishing and sometimes disturbing interactions in which one organism manipulates the behavior of another to ensure its own survival and reproduction. This phenomenon, known as parasitic behavioral manipulation, is the field of neuroparasitology. It demonstrates how parasites—from viruses and bacteria to fungi and worms—can influence the nervous systems of their hosts, often with precise and evolutionarily adapted strategies.


1. The "Bodyguard" Caterpillar: A Masterpiece of Manipulation


An outstanding example is the parasitic wasp Cotesia glomerata and its host caterpillar, the small cabbage white butterfly (Pieris rapae). The female wasp lays her eggs inside the caterpillar. After hatching, the wasp larvae feed on the caterpillar from the inside, sparing vital organs to keep the host alive.

Shortly before the caterpillar pupates, the wasp larvae leave the host and spin cocoons outside the caterpillar's body. The fascinating thing is that the caterpillar remains alive, but its behavior is drastically manipulated. It is induced to actively protect the wasp cocoons by spinning a protective layer of silk over them and aggressively fending off attackers, for example by biting or headbutting. This "bodyguard" behavior, also known as the "usurpation hypothesis," significantly increases the survival rate of the wasp pupae. After a few days, the caterpillar eventually dies because its energy reserves are exhausted.



2. Further examples from nature: From "zombie ants" to "suicide crickets"


The variety of parasitic behavioral manipulation is enormous:

  • "Zombie ants" caused by Ophiocordyceps fungi: The fungus forces infected ants to leave their colony and climb to an elevated position, where they cling to it and die. This optimizes the spore spread of the fungus. The fungus infects the ant's muscles, forming complex networks there, while the brain remains intact. The fungus is thought to produce chemicals that trigger muscle contractions.
  • "Suicide crickets" by stringworms: Stringworms (Nematomorpha) manipulate their insect hosts, such as crickets, into jumping into water and drowning. This is crucial to the worm's life cycle, as the adult worms live and mate in the water. Proteomic studies suggest that the worms alter the host's phototaxis (response to light stimuli).
  • Toxoplasma gondii and rodents: This parasite causes rodents to be attracted to the smell of cat urine, which they normally avoid. This increases the likelihood that the rodent will be eaten by a cat, allowing the parasite to continue its life cycle. The parasite forms cysts in the brain and is thought to alter neurotransmitter levels, particularly dopamine.
  • Ladybug-Wasp Virus: A wasp injects an egg and a virus into a ladybug. After the wasp larva hatches, the ladybug remains on the cocoon and twitches rhythmically to protect the pupa from predators. This behavior is attributed to the virus, which replicates massively in the host's neural tissue.
These examples demonstrate that parasites can induce highly specific and adaptive behavioral changes that represent the parasite's "extended phenotype"—the parasite extends its genetic influence beyond its own body to the host.


3. Biological Mechanisms of Host Manipulation


Parasites utilize complex molecular and physiological mechanisms to control their hosts' behavior:

  • Psychoneuroimmunological mechanisms: Parasites disrupt communication between the host's immune and nervous systems. They can manipulate the release of immune factors such as cytokines, which can influence neuronal function and induce behavioral changes, often without directly penetrating the brain.
  • Neuropharmacological mechanisms: Parasites secrete substances that act directly on the host's nervous system. They co-opt the host's natural chemical compounds, such as hormones and neuromodulators, particularly biogenic amines such as dopamine, octopamine, and serotonin, which are crucial for a variety of behaviors.
  • Genomic and proteomic mechanisms: Parasites influence gene expression and protein production in the host. Intracellular pathogens can secrete compounds that alter second messenger systems, resulting in changes in gene expression and protein production that manipulate the host's immune response and behavior.
Identifying these specific chemical compounds is an active area of research. Understanding these mechanisms could lead to the discovery of new drugs or environmentally friendly pest control strategies.


4. Microorganisms and Human Behavior: Surprising Parallels


The manipulation mechanisms observed in the animal kingdom have parallels in the human body, where microorganisms can influence our behavior and mental health.

  • The gut-brain axis: The human gut microbiome, a complex ecosystem of trillions of microorganisms, communicates bidirectionally with the brain. This communication occurs via neural pathways (e.g., vagus nerve), neuroendocrine pathways (HPA axis), immune activation, altered permeability of the gut and blood-brain barrier, and microbial production of neurotransmitters (e.g., serotonin, dopamine, GABA).
  • Impact on mental health: Research, particularly using fecal microbiome transfer (FMT), shows strong links between gut microbiome composition and mental health disorders:

    • Depression and anxiety: Transferring microbiomes from depressed patients into rats resulted in anhedonic behavior and anxiety. Patients with generalized anxiety disorder exhibit a different and less diverse gut microbiota.
    • Schizophrenia: Patients with schizophrenia exhibit significant differences in their gut microbiome. with fewer anti-inflammatory and more pro-inflammatory bacteria. Transplantation of microbiota from schizophrenic patients into mice induced deviant behavior such as hyperactivity and impaired social interaction.
    • ADHD: The gut microbiome is increasingly discussed as an important factor in the pathophysiological mechanisms of ADHD in pediatric patients.
    • Bipolar disorder and autism spectrum disorder (ASD): Significant differences in the composition of the gut microbiome have also been observed in these disorders.
  • Direct pathogens and the human brain: Specific pathogens can directly affect or invade the human central nervous system, leading to significant behavioral and psychological changes:
    • Toxoplasma gondii: Infects up to 30% of the world's population. Latent infections are associated with an increased risk of schizophrenia, aggression, sexually aggressive behavior, and increased risk-taking, presumably by altering dopamine levels in the brain.
    • Trypanosoma brucei (African sleeping sickness): Can infect the CNS and cause neurological symptoms and profound behavioral changes.
    • Bartonella henselae (cat scratch disease): Can cause neuropsychiatric manifestations such as restlessness, irritability, panic attacks, treatment-resistant depression, and severe psychotic symptoms (hallucinations, delusions).
    • Plasmodium spp. (malaria): Is associated with psychotic episodes and cognitive impairment.

5. Reflections: Autonomy and the future of research


The ability of parasites to control a host's behavior so profoundly raises fundamental questions about the nature of "free will" and the autonomy of living beings. If even complex, seemingly intentional behaviors can be controlled by external biological influences, how autonomous are our own decisions? This suggests that autonomy may be a spectrum rather than an absolute state, and that our behaviors could be subtly or profoundly influenced by our internal microbial inhabitants or external pathogens.

The host-parasite relationship is a continuous evolutionary arms race, leading to escalating sophistication in biochemical, neurological, and behavioral adaptations on both sides. Understanding these mechanisms offers enormous potential for the discovery of new chemical compounds with therapeutic benefits, for example, as novel neuropharmaceuticals, antibiotics, or antiparasitics.1 Furthermore, more environmentally friendly pest control strategies based on behavioral manipulation could be developed.

The growing recognition that microorganisms can influence human behavior requires careful ethical consideration and a responsible approach in research and public communication. It can also change societal perceptions of infections and mental health, leading to a more integrated approach. Future research will focus on further deciphering the specific molecular mechanisms of these manipulations and identifying the diverse chemical compounds involved in them, aiming to find new solutions for health and the environment.

End of Gemini content ***



Here are a few more links to interviews with Dr. Natasha Campbell-McBride






- YouTube
 
Back
Top Bottom