Monolaurin/Lauricidin anti-viral, anti-bacterial, anti-fungal, anti-yeast

[RedFox]

_http://www.advancedhealing.com/antiviral-antibacterial-actions-of-monolaurin-and-lauric-acid/

Antiviral and Antibacterial Actions of Monolaurin and Lauric Acid

Lauric acid is a 12-carbon medium chain fatty acid (MCFA) found naturally in human breast milk (6.2% of total fat) and coconut oil (47.5% by weight). Lauric acid was originally discovered when microbiologists studied human breast milk to determine the protective (anti-viral and anti-bacterial) substances which protected infants from microbial infections. Other fatty acids were also found to have antimicrobial actions but lauric acid was found to be the most active.

The esterification of lauric acid, that naturally occurs in our body, yields an amazing compound known as monolaurin (glycerol monolaurate). Monolaurin is a non-ionic surfactant¹, which possesses an even greater anti-viral and anti-bacterial activity than its precursor, lauric acid. Monolaurin, when given orally, at therapeutic doses between 2,500 – 4,500 mg/day is generally well tolerated, with loose bowels as the only negative concern. Monolaurin has been studied at medical research centers, including the Center for Disease Control (CDC), because of its high antimicrobial (anti-viral, anti-bacterial, anti-fungal, anti-yeast and anti-protozoal) activity. These studies have provided information about the anti-viral and anti-bacterial mechanisms of monolaurin. Monolaurin was found to be effective against certain Lipid Coated Bacteria (LCBs) and Lipid Coated Viruses (LCVs) – enveloped DNA and RNA viruses.

¹Surfactant: Surfactants are compounds that lower the surface tension of a liquid, allowing easier spreading, and lowering of the interfacial tension between two liquids, or between a liquid and a solid. Surfactants may act as: detergents, wetting agents, emulsifiers, foaming agents, and dispersants.

HIV-1, Influenza virus, paramyxoviruses, rubeola virus, bronchitis virus, and the herpes family of viruses (Epstein-Barr, cytomegalo, zoster, vericella-zoster and herpes type I and II). Sadly, monolaurin had no effect on diseases caused by non-enveloped viruses such as polio virus, coxsackie virus, encephalomyocarditis virus, rhinovirus, and rotaviruses.

Helicobacter pylori (H. pylori), Staphylococcus aureus and Streptococcus agalactiae.

The anti-viral and anti-bacterial action attributed to monolaurin is that of solubilizing the lipids and phospholipids in the protective envelope of these particular infective agents causing the disintegration of the lipid envelope. Recent publications have shown that monolaurin and lauric acid inhibit the replication of viruses by interrupting the communication and binding of virus to host cells and thus preventing the uncoating of viruses necessary for replication and infection. Other studies have shown that monolaurin is able to remove all measurable infectivity by directly disintegrating the protective bacterial and viral lipid envelop. Binding of monolaurin to the viral envelop also makes the virus more susceptible to degradation by host defenses, heat, or ultraviolet light.

_http://onlinelibrary.wiley.com/doi/10.1111/j.1745-4565.1982.tb00429.x/abstract

IN VITRO EFFECTS OF MONOLAURIN COMPOUNDS ON ENVELOPED RNA AND DNA VIRUSES

Monolaurin alone and monolaurin with tert-butylhydroxyanisole (BHA), methylparaben, or sorbic acid were tested for in vitro virucidal activity against 14 human RNA and DNA enveloped viruses in cell culture. At concentrations of 1% additive in the reaction mixture for 1 h at 23°C, all viruses were reduced in infectivity by >99.9%. Monolaurin with BHA was the most effective virucidal agent in that it removed all measurable infectivity from all of the viruses tested. The compounds acted similarly on all the viruses and reduced infectivity by disintegrating the virus envelope.

RNA/DNA Enveloped Viruses
_http://en.wikipedia.org/wiki/Virus_classification

DNA
Herpesviridae - Herpes simplex virus, varicella-zoster virus, cytomegalovirus, Epstein–Barr virus
Hepadnaviridae - Hepatitis B virus

RNA viruses[edit]

For more details on this topic, see RNA virus.
Group III: viruses possess double-stranded RNA genomes, e.g. rotavirus. These genomes are always segmented.
Group IV: viruses possess positive-sense single-stranded RNA genomes. Many well known viruses are found in this group, including the picornaviruses (which is a family of viruses that includes well-known viruses like Hepatitis A virus, enteroviruses, rhinoviruses, poliovirus, and foot-and-mouth virus), SARS virus, hepatitis C virus, yellow fever virus, and rubella virus.
Group V: viruses possess negative-sense single-stranded RNA genomes. The deadly Ebola and Marburg viruses are well known members of this group, along with influenza virus, measles, mumps and rabies.

Togaviridae - Rubella virus, alphavirus
Arenaviridae - Lymphocytic choriomeningitis virus
Flaviviridae - Dengue virus, hepatitis C virus, yellow fever virus
Orthomyxoviridae - Influenzavirus A, influenzavirus B, influenzavirus C, isavirus, thogotovirus
Paramyxoviridae - Measles virus, mumps virus, respiratory syncytial virus, Rinderpest virus, canine distemper virus
Bunyaviridae - California encephalitis virus, hantavirus
Rhabdoviridae - Rabies virus
Filoviridae - Ebola virus, Marburg virus
Coronaviridae - Corona virus
Bornaviridae - Borna disease virus
Arteriviridae - Arterivirus, equine arteritis virus

 

[Mountain Crown]

Very interesting, thanks for this Redfox.

 

[Oxajil]

I have been taking monolaurin for some time, and thought I'd share my experiences with it so far. I've found it's probably one of the most effective supplements I've taken, the most interesting effect it has had so far is that it's increasing my energy levels. The first thing I had noticed is that it seems to make my skin more 'clear'. For those suffering from gut issues, fogginess, low energy, etc. this might be a helpful supplement to try out. It seems to have a similar effect as lactoferrin (based on my experiences), however it seems to be more powerful, and less expensive! It'd be interesting to see what it'll do long-term.

I should add that I'm quite sensitive to coconut, whether it's coconut milk or coconut oil. I even get a reaction if I put it on my skin! However monolaurin doesn't affect me at all, so for those who can't take coconut for its benefits, this could be a better option. I should also add that I might be experiencing this (to me) strong effect because I've been dealing with a viral infection for some time (though I'm not sure if it's currently active) and monolaurin could be doing something against it.

Some additional interesting info:

The second characteristic takes advantage of the virus-disabling effect of lauric acid, the 12-carbon fatty acid found in breast milk fat and in coconut oil. Thanks to the work of Mary Enig, readers of this journal are familiar with the anti-microbial benefits of lauric acid and other short- and medium-chain fatty acids found in coconut oil. During digestion, the body breaks triglycerides (three fatty acids joined to a glycerol molecule) into di-glycerides (two fatty acids joined to a glycerol molecule), monoglycerides (one fatty acid joined to a glycerol molecule) and free fatty acids. It is the monoglycerol of lauric acid, called monolaurin, that has the strongest anti-microbial effects.

For years, I counseled my herpes patients to eat as much coconut oil, as they could stomach. However, in the past year, I discovered a product called Lauricidin, which is a concentrate or pure form of monolaurin. One dose of Lauricidin is the equivalent of taking many tablespoons of coconut oil per day, a practice most people find intolerable. I have been consistently impressed with the ability of Lauricidin to suppress herpes outbreaks, not to mention yeast problems like candida (monolaurin is also a potent anti-fungal agent), and allow people to get off their antiviral drugs. It is a safe extract, which can be taken long term. The usual dose to suppress the herpes is about 1/2 to 1 scoop, one to three times per day. It should be swallowed, not chewed, and always taken with some food. The dose should be increased slowly as tolerated and as gauged by its effectiveness.

I take about 1 teaspoon of monolaurin pellets after each meal (three times in total). Here is the product I got:

US: _http://www.amazon.com/Lauricidin-227-gram-8oz-jar/dp/B004I8SMOQ/ref=sr_1_1?s=hpc&ie=UTF8&qid=1428482961&sr=1-1&keywords=lauricidin

EU: _http://www.amazon.de/Med-Chem-Labs-Lauricidin-Monolaurin-gramm/dp/B00HU0C8F8/ref=sr_1_1?ie=UTF8&qid=1432800370&sr=8-1&keywords=lauricidin

I know it's a bit expensive, but so far it's worth it! I remember that a doctor, during one of the Sott radio shows, mentioned coconut oil being helpful for diabetes patients as well, so monolaurin might be helpful for diabetics too:

"Diabetics are subject to increased risk and severity of infections. Ultra-Monolaurin is useful for these infections because of its anti bacterial and anti viral properties. Monolaurin controls pathogenic bacteria without compromising the normal flora in the gastrointestinal tract"

Many thanks to Laura for mentioning it, and RedFox thank you for starting this thread!

 

[Laura]

I'm taking it too and I swear that, along with the oak bark extract, it really helps with energy.

 

[Oxajil]

I'm taking it too and I swear that, along with the oak bark extract, it really helps with energy.

It really does help, and quite immediate too! I haven't tried out oak bark extract yet, but will be getting it soon!

 

[H-KQGE]

Just to say that if anyone is buying from the UK, be careful not to buy the one that costs... £74! If the other one is unavailable then best to wait (£29). Or enquire directly about availability. I see this "doublet" thing for quite a few products, dunno if they're trying to catch some people out. Sounds obvious but I thought I'd still mention it all the same. Thanks for the information Oxajil + Laura.

 

[Nienna]

I have been taking monolaurin for some time, and thought I'd share my experiences with it so far. I've found it's probably one of the most effective supplements I've taken, the most interesting effect it has had so far is that it's increasing my energy levels. The first thing I had noticed is that it seems to make my skin more 'clear'. For those suffering from gut issues, fogginess, low energy, etc. this might be a helpful supplement to try out. It seems to have a similar effect as lactoferrin (based on my experiences), however it seems to be more powerful, and less expensive! It'd be interesting to see what it'll do long-term.

Thank you for sharing this, Oxajil. I have the same problems with coconut oil as you (even with the skin), and, being allergic to dairy, I can't even tolerate the lactoferrin (nor anything with "lacto" in it it seems).

The oak wood extract, after taking it for 5 months, has started to work a bit on my histamine problem just a bit, but a bit is better than nothing so I'm going to continue taking it for another 3 months. I'm intrigued by this monolaurin as I'd like to get some of the benefits of coconut oil so I'm thinking of trying it out when I can afford it.

Again, thank you.

 

[dugdeep]

I'm taking it too and I swear that, along with the oak bark extract, it really helps with energy.

This would make sense, since lauric acid is a medium chain triglyceride (MCT), which more readily enter the mitochondria and are more easily converted to ketones. I'm going to look into how much lauric acid is found in MCT oil, which I take daily. Might be a less expensive way to reap the same antimicrobial benefits.

 

[Gaby]

Thank you for sharing! I want to experiment with it too.

I just got it from amazon. :)

 

[Oxajil]

Thanks Ascien for mentioning that, I noticed the same on amazon.de, sneaky!

They also sell it here:
_http://www.liferight.co.uk/shop/lauricidin/
_http://www.jgsupplements.com/products/lauricidin-pure-monolaurin-227g.html

This would make sense, since lauric acid is a medium chain triglyceride (MCT), which more readily enter the mitochondria and are more easily converted to ketones. I'm going to look into how much lauric acid is found in MCT oil, which I take daily. Might be a less expensive way to reap the same antimicrobial benefits.

Thanks dugdeep, that'd be interesting to know!

Thank you for sharing! I want to experiment with it too.

I just got it from amazon. :)

I have the same problems with coconut oil as you (even with the skin), and, being allergic to dairy, I can't even tolerate the lactoferrin (nor anything with "lacto" in it it seems).

The oak wood extract, after taking it for 5 months, has started to work a bit on my histamine problem just a bit, but a bit is better than nothing so I'm going to continue taking it for another 3 months. I'm intrigued by this monolaurin as I'd like to get some of the benefits of coconut oil so I'm thinking of trying it out when I can afford it.

Okay, hope it helps.