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The organized screening of the breast cancer saves lives, but the mammography is an examination to handle with more precautions than it is the case today. This is the main conclusion of the study in the review " international journal of Radiation Biology" that must be presented on october 21th in the French days of the Radiology.
According to this thesis, the exposure of the breast cellson on weak radiation (mamography) provokes damages on their DNA. Brought to light for the first time, such an effect drives to wonder the harmlessness
of the mamographic examination and in particular on th possibility it can lead to cancers.
Catherine Colin First author of this thesis warns in a general way, the epidemiologie doesn't show increase of cancer for exposure to divers types of radiations (for the women of 50 years) . But the question of harmlessness arises for the women at risk (the women who must be followed 50 years even 40 years.
With these results ,the Health High Autority (in french HSA) has to lead a reflexion for new recommendations for the radiological community.
To reach their conclusions, Catherine Colin and her co-authors used breast cells taken from thirty women, having or not having a family predisposition of the breast cancer.
Each of these cellular cultures was twice irradiated with a few minutes interval between two radiations ,the cellular cultures received 2 milligrays (mGy) the equivalent of a standard mamography.
The researchers then observed the nucleus of the irradiated cells and they were able to distinguish that even in small doses the DNA presented breaks. An important observation is that the effect of two successive irradiations of 2 mGy produces more breaks on the DNA than one irradiation of 4 mGy explains the c o-author Nicolas Foray
(researcher in the center of cancer research in Lyon).
Nicolas Foray goes on We noticed that these damages of the DNA were not quite repairedafter 24 hours and itwas even more marked in women's cells presenting a high family risk of breast cancer. We also observed at these subjects the existence of very damaged cells as if the system was carried away with an accumulation of breaks in the DNA . We were able to notice more than one hundred breaks by cell
This article is appeared in "Le monde" on Saturday , October 22rd 2011 may be is it interresting to comment ?
According to this thesis, the exposure of the breast cellson on weak radiation (mamography) provokes damages on their DNA. Brought to light for the first time, such an effect drives to wonder the harmlessness
of the mamographic examination and in particular on th possibility it can lead to cancers.
Catherine Colin First author of this thesis warns in a general way, the epidemiologie doesn't show increase of cancer for exposure to divers types of radiations (for the women of 50 years) . But the question of harmlessness arises for the women at risk (the women who must be followed 50 years even 40 years.
With these results ,the Health High Autority (in french HSA) has to lead a reflexion for new recommendations for the radiological community.
To reach their conclusions, Catherine Colin and her co-authors used breast cells taken from thirty women, having or not having a family predisposition of the breast cancer.
Each of these cellular cultures was twice irradiated with a few minutes interval between two radiations ,the cellular cultures received 2 milligrays (mGy) the equivalent of a standard mamography.
The researchers then observed the nucleus of the irradiated cells and they were able to distinguish that even in small doses the DNA presented breaks. An important observation is that the effect of two successive irradiations of 2 mGy produces more breaks on the DNA than one irradiation of 4 mGy explains the c o-author Nicolas Foray
(researcher in the center of cancer research in Lyon).
Nicolas Foray goes on We noticed that these damages of the DNA were not quite repairedafter 24 hours and itwas even more marked in women's cells presenting a high family risk of breast cancer. We also observed at these subjects the existence of very damaged cells as if the system was carried away with an accumulation of breaks in the DNA . We were able to notice more than one hundred breaks by cell
This article is appeared in "Le monde" on Saturday , October 22rd 2011 may be is it interresting to comment ?