primechild
Jedi
Brief
"According to conventional wisdom, proteins must fold into rigid shapes to perform such tasks as binding to specific target molecules. But recent work suggests that one third of the types that exist in humans are partially or completely unstructured.
Although lack of folding was long considered a pathology, it need not hamper functionality—and it is in fact often crucial to a protein’s workings.
Unstructured proteins may have played important roles during evolution, and a better understanding of their true nature may also lead to the design of novel drugs."
_http://www.scientificamerican.com/article.cfm?id=the-orderly-chaos-of-proteins
Protein Video extras
under brownian motion
binding to a kinase enzyme
kinesin walking
_http://www.scientificamerican.com/article.cfm?id=flexible-proteins-web-extra
"According to conventional wisdom, proteins must fold into rigid shapes to perform such tasks as binding to specific target molecules. But recent work suggests that one third of the types that exist in humans are partially or completely unstructured.
Although lack of folding was long considered a pathology, it need not hamper functionality—and it is in fact often crucial to a protein’s workings.
Unstructured proteins may have played important roles during evolution, and a better understanding of their true nature may also lead to the design of novel drugs."
_http://www.scientificamerican.com/article.cfm?id=the-orderly-chaos-of-proteins
Protein Video extras
under brownian motion
binding to a kinase enzyme
kinesin walking
_http://www.scientificamerican.com/article.cfm?id=flexible-proteins-web-extra
