White buffalo are American bison (American buffalo) that are considered to be sacred signs in several Native American religions, and thus have great spiritual importance in those cultures and are visited for prayer and other religious ceremonies. Buffalo are normally brown in color; white buffalo can result from one of several physical conditions:
They may be leucistic, with white fur but blue eyes, instead of the pink seen in albinos.
They may have a rare genetic condition which causes a buffalo to be born white, but to become brown within a year or two as it matures.
They may be albinos, in which case they will remain unpigmented throughout their lives, and may also have hearing and vision problems.
They may be beefalo, a bison-cattle crossbreed, and thus have inherited the white coloration from their cattle ancestry.
White buffalo are extremely rare; The National Bison Association has estimated that they only occur in approximately one out of every 10 million births.