This has been my own approach for 1 year now, and I have to say it's been great. I decided to start with this because of mainly two reasons:
1- Lack of time to go to the gym, and
2- Small and uncomfortable injuries such as tennis elbow and constant shoulder pain.
What I now have at home is one weighted vest and a pull-up bar (with a special band for assisted pull-ups). So, my training is very simple: weighted paused-rep push-ups (holding 2 seconds at the bottom), assisted pull-ups also using the paused-rep approach, and for legs, one day normal weighted squats with paused-reps as well, and the other day just doing horse stances. All exercises are done with full range of motion (ROM). I also have to say that I chose this because of my age (52 y.o.) and my tendency to get injured when I use heavy weights.
I've learnt some of these concepts from this guy called Kyle Boges; his YT channel is
K boges
Of everything I've heard in the fitness industry, what this guy says seems to be very feasible, at least for someone my age.