Caprylic Acid - treatment of intractable medical problems

Laura

Laura

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Caprylic acid in the effective treatment of intractable medical problems of frequent urination, incontinence, chronic upper respiratory infection, root canalled tooth infection, ALS, etc., caused by asbestos & mixed infections of Candida albicans, Helicobacter pylori & cytomegalovirus with or without other microorganisms & mercury.

Omura Y1, O'Young B, Jones M, Pallos A, Duvvi H, Shimotsuura Y.
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Abstract

There are many causes of frequent urination. Whenever water or fluids are consumed, the patient has to urinate within 10 or 20 min. Often urinary bladder examinations & blood tests show no significant abnormalities, & treatment by anti-bacterial or anti-viral agents does not improve the symptoms significantly. In intractable frequent urination with difficulty holding urine, as well as other intractable medical problems such as frequent coughing, white pus in gingiva, infection of the apex of a root canalled tooth, slow-healing wounds, & ALS, the authors often found coexisting mixed infections of Candida albicans (C.A.), Helicobacter pylori (H.P.), & Cytomegalovirus (CMV) with or without additional bacterial (Chlamydia trachomatis, etc.) or viral infections & increased Asbestos, with or without Hg deposits. We often found various degrees of mixed infections with C.A., H.P., & CMV in the external sphincters of the urethra & in the Trigone of the urinary bladder which consists of (1) a horizontal, band-like area between the 2 ureter openings & (2) the funnel shaped part of the Trigone at the lower half of the urinary bladder. In the coexistence of significant amounts of C.A., H.P. & CMV, the infection cannot be reduced by otherwise effective medicines for H.P. & CMV. However, one optimal dose of Diflucan, or Caprylic acid taken orally or externally applied, rapidly reduced the symptoms significantly. We found the best treatment is to give a combination of an optimal dose of Caprylic acid orally in the form of "CaprilyCare" or "Caprylic Acid," with a capsule of Omega-3 Fish Oil as an anti-viral agent, Amoxicillin, Substance Z & a Cilantro tablet. We found that an optimal dose of Caprylic acid increases normal cell telomere (NCT) to a desirable 750 ng BDORT units while Diflucan increases NCT by only 25 ng BDORT units, & with Omega-3 fish oil, leads to a mutual cancellation of both drugs. Thus, Caprylic acid is superior to & less expensive than Diflucan, & has potential application for anti-cancer, anti-aging, anti-Alzheimer's disease, anti-Autism, anti-infection, & general circulatory improvement.

http://www.ncbi.nlm.nih.gov/pubmed/21830350
 
Gleaned from around the web. Doesn't seem to be much about it.


Medium chain triglycerides (MCTs) are partially man-made fats. The name refers to the way the carbon atoms are arranged in their chemical structure. MCTs are generally made by processing coconut and palm kernel oils in the laboratory. Usual dietary fats, by comparison, are long-chain triglycerides. People use MCTs as medicine.

MCTs are used along with usual medications for treating food absorption disorders including diarrhea, steatorrhea (fat indigestion), celiac disease, liver disease, and digestion problems due to partial surgical removal of the stomach (gastrectomy) or the intestine (short bowel syndrome).

MCTs are also used for “milky urine” (chyluria) and a rare lung condition called chylothorax. Other uses include treatment of gallbladder disease, AIDS, cystic fibrosis, Alzheimer's disease, and seizures in children.

Athletes sometimes use MCTs for nutritional support during training, as well as for decreasing body fat and increasing lean muscle mass.

MCTs are sometimes used as a source of fat in total parenteral nutrition (TPN). In TPN, all food is delivered intravenously (by IV). This type of feeding is necessary in people whose gastrointestinal (GI) tract is no longer working.

Intravenous MCTs are also given to prevent muscle breakdown in critically ill patients.

How does it work?

MCTs are a fat source for patients who cannot tolerate other types of fats. Researchers also think that these fats produce chemicals in the body that might help fight Alzheimer's disease.



Caprylic acid is a fatty acid that is found naturally in coconut and breast milk. This saturated fatty acid, also known as octanoic acid, is also present in butter and palm oil. According to the Health Sciences Institute, caprylic acid is known to have numerous health benefits. One of the most well known health benefits associated with the ingestion of caprylic acid, is its ability to treat the overgrowth of yeast-like fungus that can live and grow in your intestines.

As a yeast-fighting agent, it is theorized that the anti-fungal activity of caprylic acid dissolves the cell membrane of the candida yeast cells and causes them to die off. Available in pill, tablet or capsule form, because of the fat solubility, it is recommended that you take caprylic acid with either dietary fat like butter or salad oil or in conjunction with omega-3 fatty acids or flax seed oil. It is also recommended that you take the supplement with food to avoid any stomach discomfort.

According to the Physicians Desk Reference Guide to Nutritional Supplements, in addition to treating bacterial issues, caprylic acid may also have a beneficial effect on high blood pressure. Other benefits may include helpful relief from those who suffer from Chron's disease, an inflammatory intestinal condition. According to a study conducted by a Japanese team of researchers at the graduate school of medicine at Chiba University, caprylic acid inhibits and suppresses the secretion of IL-8, the gene present in the intestines of Chron's disease patients.

If you take caprylic acid, you will also need to take a good probiotic such as lactobacilli or acidophilus, to restore good bacteria in your body and to control the growth of candida, while staying away from certain foods that trigger yeast overgrowth such as yeast and fermented products. Avoid beer, wine, alcoholic beverages, cheese, pickled vegetables and treated meats, cheese, and mushrooms. Maintaining a diet low in sugar and refined carbohydrates also helps starve the candida albican yeast.

The recommended dosage of caprylic acid is 300 mg to 2000 mg per day and has to be taken orally with meals. Usually, doctors advise to start with a small dose and increase the dose gradually. In order to yield maximum benefits, you should avoid certain food substance that tend to promote growth of yeast in your body. It includes fermented products like beer, wine, alcoholic beverages, processed meat, mushrooms, pickled vegetables, etc. You should also follow a low sugar diet that will deprive candida albican from its food. There are no serious side effects of caprylic acid. However, some people experience diarrhea, nausea, vomiting, heartburn, etc. they will subside once the body get used to the supplement. During this time, one should drink plenty of water to prevent dehydration.

Caprylic acid may alter the effects of drugs that are highly bound to albumin. Patients taking any medications should check the package insert, and consult with a qualified healthcare professional, including a pharmacist.

Research
Caprylic acid infusion acts in the liver to decrease food intake in rats.
Physiol Behav. 2006.
Hepatic portal vein (HPV) infusion of the medium chain fatty acid caprylic acid for 90 min beginning at dark onset in 18-h food-deprived male rats reduced the size of the first nocturnal meal about 40% and reduced 24-h food intake by about 15%. Identical infusions into the vena cava affected neither initial meal size nor food intake. HPV caprylic acid infusion attenuated the postprandial decreases in plasma free fatty acids and beta-hydroxybutyrate. These data indicate that caprylic acid acts in the liver to produce a signal that inhibits feeding and that this inhibitory effect may be related to increases in hepatic fatty acid oxidation rather than be the result of aversion or toxicity.


Outlined below are a number of benefits of Caprylic acid.

Reduction of overgrown tissues

Caprylic acid has the capacity to ensure that any yeast like fungus within your body does not overgrow. Most of the time, yeasts like-fungus are found growing within your intestines. As such, the Caprylic acid will prevent it from overgrowing.

Fights Candida of the intestines

Candida, which is a condition that results from overgrown yeast fungus especially in the gut area, can be treated by use of Caprylic acid. It will dissolve all candida cell tissues making them to die. Therefore, your body becomes free of problems that result from candida. For instance, problems of having bowel that is irritable, bloating of the abdomen as well as long-lasting weariness.

Fighting skin infections

When the Caprylic acid is taken orally, it helps in reducing yeast infections on your body by dissolving cell walls of any bacteria, which may cause infections on your skin. In addition, mouth infections especially because of overgrown yeast can be treated using Caprylic acid. For years, Caprylic acid has been used to treat as well as in the soothing of a number of skin infection like ringworm, gastroenteritis and other related infections.

Act as an essential Fatty Acid

Caprylic acid just like omega 3 or even omega 6 is seen as a very significant fatty acid in the body. It is a very essential complement of most parts of the body. As such, it helps in regulating your vitality, growth as well as your mentality. This makes the Caprylic aid a must-have if off you want your body to remain healthy.

Source of Energy

Caprylic acid is an important part of your body fitness journey. Since it is a fatty acid, not even that alone, it is a medium-chain triglyceride. It thus helps in boosting your body energy unlike most other saturated fats, which pass through a long process before they are fully digested.

From the foregoing, it is clear that Caprylic acid is an integral part of your body. Therefore, the next time you wish to acquire a healthy body, include Caprylic acid in your diet and you will be amazed by the results that you will get. You will not only get a healthy body but also gain enough energy for your daily activities.
 
This lexicon You may find useful:

_http://www.planktoleum.info/food/IUPAC-Lexicon-Of-Lipid-Nutrition.pdf

Unfortunately it is not giving value of coconut oil there. I see that a lot of sites are giving information that coconut oil has high content of caprylic acid but I have not found the source yet.

Maybe the easiest is to buy supplement then.
 
Caprylic acid is present in goat milk mostrly but in small amount in the coconut and palm oil too. It has pronounced antibacterial properties.

http://en.wikipedia.org/wiki/Caprylic_acid
http://udini.proquest.com/view/investigating-the-antimicrobial-pqid:2433204121/

quote

Fatty acids as antimicrobial agents Organic acids have been used for centuries by humans as food preservatives because of their antimicrobial activity. Most of these organic acids (lactic acid, tartaric acid, malic acid and proprionic acid) exist naturally in fruits and vegetables. Use of fatty acids as an timicrobials has been practiced by humans for centuries as a component of soaps and sa- nitizers, but extensive study of antimicrobial property of fatty acids has been carried out only recently (Traul et al., 2000). One of the reasons for this investigation is concern in the scientific community over antibiotic resistance of microorganisms. Medium chain fatty acids A number of medium chain fatty acids and their derivatives especially monoglycerides have been found to be very effective against many micro-organisms including gram positive bacteria, gram negative bacteria, Chlamydia, and enveloped viruses (Petschow et al., 1996; Bergsson et al., 1998; Thormar et al., 1987).

The mechanisms through which me dium chain fatty acids and their monoglycerides exert their antibacterial properties are incompletely understood. Kato and Shibasakii reported that antibacterial action of me dium chain fatty acids may involve disruption of the cell membrane permeability barrier (kato et al., 1976). Freese et al. reported that the cell membrane is the primary target for the antibacterial effect of fatty acids (Freese et al., 1973). It is proposed that these com pounds inhibit amino acid uptake by diffusing into the bacterial cell and lowering pH of the protoplasm (Shibasaki et al., 1978; Sun et al., 2002).

Lower pH of the protoplasm may also disrupt the normal function of intracellular enzymes (Viegas et al., 1997). Re searchers have reported that the expression of virulence factors in Staphylococcus aureus is inhibited by glycerol monolaurate (Projan et al., 1994; Ruzin et al., 1998). Medium chain fatty acids were also reported to be involved in decreasing bacterial colonization and invasion of Salmonella Enteritidis in the intestines of the chicken (Van Immerseel et al., 2004). Caprylic acid Caprylic acid is a medium chain fatty acid that contains 8 carbons in its structure. Capryl ic acid is naturally present in breast milk, bovine milk and coconut oil (Jensen et al., 2002). The chemical formula of caprylic acid is CgH160 with a formula weight of 144.22. It is a liquid at room temperature and is not soluble in water but soluble in organic sol- vents. Its melting point is 16 C. Even at high concentrations caprylic acid is a non toxic compound. A toxicity study conducted by Jenner et al. indicated that an oral lethal dose of caprylic acid in rats is 10.1 g/kg body weight (Jenner et al., 1964).

Caprylic acid was 10 designated GRAS (Generally Recognized as Safe) as a food additive by the Food and Drug Administration in 1994 (GRAS 184.1024). Caprylic acid is effective in killing the herpes simplex virus (HSV-1), respiratory syncytial virus (RSV), Haemophilus influenza and group B streptococci (Isaacs at al., 1995). Caprylic acid has been proven to be an effective bactericidal against E. coli 0157:H7. The bacterial population was undetectable within 1 minute of incubation in buffered rumen fluid at pH 5.6 and 6.8 with caprylic acid at a concentration of 50 mM. Caprylic acid was found to be more effective at a pH of 5.6 than at a pH of 6.8. This study also revealed that the inhibitory effect of caprylic acid at 35 mM is minimal, indi cating the usefulness of this compound as a dietary supplement to reduce the ruminal load of E.coli 0157:H7 (Annamalai et al., 2004). M.K.M. Nair and colleagues proved that ca prylic acid is effective against major mastitis pathogens (Nair et al., 2005). The count of Streptococcus agalactiae, Streptococcus dysagalectia, and Streptococcus uberis was re duced by 5 log cm/ml within 1 min. of incubation with 100 mM caprylic acid. A 100 mM concentration of caprylic acid reduced the Staphylococcus aureus population by 5 log cfu/ml in 6 hrs. A 100 mM concentration of caprylic acid in milk reduced the E.coli count by 5 log cfu/ml within 1 minute of incubation (Nair et al., 2004). Monocaprylin Monocaprylin has a chemical formula of C11H22 O4 and its formula weight is 218.3. Mo nocaprylin (1-capryloyl-rac-glycerol) is the monoglyceride ester of caprylic acid. This compound is soluble in organic solvents like ethanol. In a study conducted at the Univer sity of Connecticut, monocaprylin showed a strong antibacterial property against five ma jor mastitis pathogens: Streptococcus agalactiae, Streptococcus dysagalactiae. Strepto- 11 coccus uberis, Staphylococcus aureus, and Escherichia coli. At a 50 mM concentration of monocaprylin at 39 C, the population of Streptococcus agalactiae, Streptococcus dy- sagalactiae, and Streptococcus uberis was reduced by 6 log cfu/ml within 6 hrs of incu bation. Staphylococcus aureus and the Escherichia coli population were reduced by 5 log CFU/ml within 24 hrs of treatment with a 50 mM concentration of monocaprylin (Nair et al., 2005).

Monocaprylin was proven to be highly effective in killing E coli 0157:H7, a ma jor food borne pathogen. At a 5 mM concentration of monocaprylin in apple juice incu bated at 23 C, all E. coli 0157:H7 were killed within 3 days. When apple juice was in oculated with E. coli 0157:H7 and incubated at 4° C with a 5 mM concentration of mon- caprylin, no bacteria were detected in the apple juice by the 14th day (Nair et al., 2005).
 
Hi,
on page nutritiondata.com
_http://nutritiondata.self.com/facts/fats-and-oils/508/2
it looks like that coconut oil is really high on caprylic acid.
On 100g there is 7.5 g of this acid.
 
I remember reading about caprylic acid and candida, and wrote a post in the Candida thread about it. It is available as a supplement. Coconut oil (either by ingesting it directly or using it in food) also has lauric acid which can help with candida as well.
 
This is very interesting. I seem to recall reading something some months back about this and lauric acid, both of which are present in breast milk and coconuts. It was discussed how some of the byproducts of these two acids work by disruption of the lipid membrane of many organisms. I am on my kindle as my computer is broken, but there is some information about it here http://www.westonaprice.org/know-your-fats/new-look-at-coconut-oil which is similar to what had been said in the other replies.

On a personal note, I have used coconut oil myself with very noticeable results. I was quite certain some months ago that I was developing a tooth infection and after a few days of taking a few tablespoons of coconut oil throughout the day, all symptoms were gone with no recurrence. I also had an ulcer at one point which cleared up completely in only 24-36 hours by applying the oil directly to it a few times a day.
 
Cześć,
And here it is cool search tool on this website nutritiondata.com

http://nutritiondata.self.com/tools/nutrient-search

which allows You to find food based on highest content of selected nutrient.
Based on that site, coconut is the highest one on caprylic acid.
 
Arwenn said:
I remember reading about caprylic acid and candida, and wrote a post in the Candida thread about it. It is available as a supplement. Coconut oil (either by ingesting it directly or using it in food) also has lauric acid which can help with candida as well.
Click to expand...

It's very good for digestive issues and intestinal health.

Yep, you can find Now Foods brand on Amazon:
http://www.amazon.com/Foods-Caprylic-Acid-600mg-Softgels/dp/B001AWWC4O/ref=cm_cr_pr_product_top
 
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