Essential Oils and dmso: dilution?

[ermete55]

Does anyone have experience in the use of essential oils with dmso ? I would try lavender and cypress oil with dmso( for better penetration) but I do not know how to dilute the solution. Take dmso diluited with purified water at 50% (one spoon dmso: one spoon purified water) and after add drops of essential oil ? How many drops? Thank you very much

 

[Lilou]

Re: Essential Oils and dmso: diluition

I have never used essential oil in combination with DMSO. Since the DMSO crosses the blood-brain barrier, it carries the essential oil across into the brain as well. For that reason, I am a bit cautious about what I mix with it.

If you do choose to give it a try, the essential oil itself should be diluted in a carrier oil, such as olive oil before mixed with DMSO. The essential oil should also be pharmaceutical grade. To decrease skin irritation, most people dilute the DMSO to 50 or 70% solution. It is important that the dilution of DMSO be done with distilled water so that all the salts are removed and does not contain impurities.

I did find a cancer study that used DMSO and tea tree oil against tumors in mice with good results. _http://www.ncbi.nlm.nih.gov/pubmed/22727730

I also found this site, _http://www.integratedhealthblog.com/tag/dmso/ , that sells a DMSO/essential oil mixture for pain relief.

There is also this article, http://health-matrix.net/2011/03/15/dmso-the-real-miracle-solution/ for a good overview of DMSO and a long thread here on the forum http://cassiopaea.org/forum/index.php/topic,17014.0.html

As always, it is best to read everything you can find for a good understanding before experimenting. :)

 

[Laura]

Like Lilou, I'm not sure that it is a good idea to carry essential oils into the body with DMSO. One would need expert knowledge of the constituents of the oils, the planned effect, and more to even contemplate such a process.

 

[ermete55]

in the market there are dmso plus essential oil product. So they are dangerous?

 

[Lilou]

in the market there are dmso plus essential oil product. So they are dangerous?

I wouldn't trust them myself. In the scientific study using DMSO and tea tree oil, the scientists said they are working on isolating the specific terpene responsible for the action against tumors. Other effects on the health of the mice were not discussed, but I suppose it is enough that they were "given cancer"!

An essential oil has several components and even the same kind of oil, if distilled at too high of heat, for example, will have destroyed some, if not all, of its healing properties. Everybody and their brother are distilling oils, but few are producing high quality.

Like Laura said, it would not be possible to know all the effects it may cause without expert knowledge.

 

[ermete55]

Hi lilou, thank you. I wanted to use the essential oil of cypress with dmso for chelation hemosiderin spots, I did not think that essential oils were dangerous with dmso

 

[Laura]

Hi lilou, thank you. I wanted to use the essential oil of cypress with dmso for chelation hemosiderin spots, I did not think that essential oils were dangerous with dmso

Do you have any disease that causes these spots?

 

[ermete55]

No, there are patch from old bruise. I'm looking for a way to chelation, dmso is the only way to reach the depth of this stain

 

[lainey]

I agree about not mixing the two. I have limited knowledge on the subject but it would be better to play it safe and do them separately. However, I did a search on mixing the 2 and came across a product that had the two mixed called "Warrior Mist".

Beyond its effectiveness against pain, what I like about Warrior Mist is that it contains all-natural ingredients. What does that mean? Most of its ingredients are herbal like peppermint oil, lavender oil, and organic coconut and olive oils.

Warrior Mist contains: DMSO (99.999% pure), peppermint oil (the source of menthol in the product), organic olive oil, distilled water, MSM, magnesium chloride, lemon oil, lavender oil, and organic coconut oil.

Warrior Mist contains no harsh chemicals or synthetic preservatives (like parabens, dimethicone, or phenoxyethanol). What else would you expect from a formulator like Dr. Hank Liers or a company like Health Products Distributors?

For anyone who cares about NOT putting toxic chemicals on their skin, Warrior Mist is a high-purity formula worthy of consideration. It is a pure, simple, and effective formula.

Warrior Mist comes in a spray bottle made of glass, not plastic. Shake it, then spray it. Gently massage the area of application to assist absorption. That’s all there is to it.

WARRIOR MIST APPLICATIONS FOR PAIN

Warrior Mist is effective for many applications, including pain relief for joints (wrists, elbows, knees, ankles), bruises and scratches, as well as insect bites and skin irritations. I occasionally I spray it directly into my mouth for throat relief, especially in winter or during allergy season (although technically it is not for internal use).

http://www.integratedhealthblog.com/tag/dmso/

Not really sure what to make of it though. I'll continue looking.

 

[Laura]

No, there are patch from old bruise. I'm looking for a way to chelation, dmso is the only way to reach the depth of this stain

What I've been using on bruises is a bit of pure comfrey salve with a few drops of dmso mixed in.

 

[ermete55]

No, there are patch from old bruise. I'm looking for a way to chelation, dmso is the only way to reach the depth of this stain

What I've been using on bruises is a bit of pure comfrey salve with a few drops of dmso mixed in.

even for hemosiderin stain?

 

[ermete55]

I agree about not mixing the two. I have limited knowledge on the subject but it would be better to play it safe and do them separately. However, I did a search on mixing the 2 and came across a product that had the two mixed called "Warrior Mist".

Beyond its effectiveness against pain, what I like about Warrior Mist is that it contains all-natural ingredients. What does that mean? Most of its ingredients are herbal like peppermint oil, lavender oil, and organic coconut and olive oils.

Warrior Mist contains: DMSO (99.999% pure), peppermint oil (the source of menthol in the product), organic olive oil, distilled water, MSM, magnesium chloride, lemon oil, lavender oil, and organic coconut oil.

Warrior Mist contains no harsh chemicals or synthetic preservatives (like parabens, dimethicone, or phenoxyethanol). What else would you expect from a formulator like Dr. Hank Liers or a company like Health Products Distributors?

For anyone who cares about NOT putting toxic chemicals on their skin, Warrior Mist is a high-purity formula worthy of consideration. It is a pure, simple, and effective formula.

Warrior Mist comes in a spray bottle made of glass, not plastic. Shake it, then spray it. Gently massage the area of application to assist absorption. That’s all there is to it.

WARRIOR MIST APPLICATIONS FOR PAIN

Warrior Mist is effective for many applications, including pain relief for joints (wrists, elbows, knees, ankles), bruises and scratches, as well as insect bites and skin irritations. I occasionally I spray it directly into my mouth for throat relief, especially in winter or during allergy season (although technically it is not for internal use).

http://www.integratedhealthblog.com/tag/dmso/

Not really sure what to make of it though. I'll continue looking.

thank you. I don't know if try or not.

 

[Laura]

No, there are patch from old bruise. I'm looking for a way to chelation, dmso is the only way to reach the depth of this stain

What I've been using on bruises is a bit of pure comfrey salve with a few drops of dmso mixed in.

even for hemosiderin stain?

One thing I notice that is used for "bleaching" the skin is niacinamide. Perhaps some capsules of that could be opened and sprinkled in the mix? While the studies I've read talk about it in relation to melanin, it is possible that it would work on other causes. Also doesn't hurt to take niacinamide regularly as suggested in the Iodine Protocol.

https://en.wikipedia.org/wiki/Skin_whitening

Also:

– Niacinamide is the active form of Vitamin B3. A safe, nonirritating cosmeceutical ingredient which research shows can offer a number of benefits in improving the appearance of aged and photodamaged skin and improve skin moisturization.

While its precise mechanism of action is not clear, clinical studies have shown topical niacinamide to be effective in improving skin texture and the appearance of hyperpigmented spots, with improvement in red blotchiness and the reduction of the severity of fine lines.

– It has been shown to stimulate collagen synthesis and production of ceramide, a lipid compound that contributes to the functional and structural integrity of the skin barrier. Theoretically, by improving barrier integrity, niacinamide may help the skin become more resistant to external irritants.

– Topical use of niacinamide has been shown in clinical studies to effectively reduce the rate of sebum excretion and its casual serum levels. http://thesizzlingmommy.com/2015/01/i-just-discovered-that-niacinamide-can-double-as-an-anti-ageing-and-lightening-ingredient.html

http://www.ncbi.nlm.nih.gov/pubmed/12100180

The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.
Hakozaki T1, Minwalla L, Zhuang J, Chhoa M, Matsubara A, Miyamoto K, Greatens A, Hillebrand GG, Bissett DL, Boissy RE.
Author information
Abstract
BACKGROUND:

Cutaneous hyperpigmentation occurs in multiple conditions. In addition, many Asian women desire a lighter skin colour. Thus, there is a need for the development of skin lightening agents. Niacinamide is a possible candidate.
OBJECTIVES:

To investigate the effects of niacinamide on melanogenesis in vitro and on facial hyperpigmentation and skin colour in vivo in Japanese women.
METHODS:

Melanin production was measured in a purified mushroom tyrosinase assay, cultured melanocytes, a keratinocyte/melanocyte coculture model, and a pigmented reconstructed epidermis (PREP) model. The clinical trials included 18 subjects with hyperpigmentation who used 5% niacinamide moisturizer and vehicle moisturizer in a paired design, and 120 subjects with facial tanning who were assigned to two of three treatments: vehicle, sunscreen and 2% niacinamide + sunscreen. Changes in facial hyperpigmentation and skin colour were objectively quantified by computer analysis and visual grading of high-resolution digital images of the face.
RESULTS:

Niacinamide had no effect on the catalytic activity of mushroom tyrosinase or on melanogenesis in cultured melanocytes. However, niacinamide gave 35-68% inhibition of melanosome transfer in the coculture model and reduced cutaneous pigmentation in the PREP model. In the clinical studies, niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use.

CONCLUSIONS:

The data suggest niacinamide is an effective skin lightening compound that works by inhibiting melanosome transfer from melanocytes to keratinocytes.

https://www.oskiaskincare.com/skin-nutrition/patented-actives/niacinamide/

 

[lainey]

I can across another study done on essential oils and DMSO. Antimicrobial Action of Essential Oils: The Effect of Dimethylsulphoxide on the Activity on Cinnamon Oil.
http://www.jonnsaromatherapy.com/pdf/Hili_Antimicrobial_Action_of_Essential_Oils_1997.pdf

Fifty-one essential oils extracted from plants of known origin were tested for their antimicrobial activity against three bacteria, Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli and four yeasts, Torulopsis utilis, Schizosaccharomyces pombe, Candida albicans and Sacccharomyces cerevisiae using the drop diffusion method. All showed antimicrobial activity against at least one of the micro-organisms. Following this preliminary screening, 13 essential oils showing anti-microbial activity against at least five of the micro-organisms were tested in the range 50ug ml-1 to 500ug ml-1 using broth micro dilution techniques with dimethylsulphoxide (DMSO) as a dispersing solvent. The concentration of most of the oils required for total inhibition of growth was >500ug ml-1. Further studies on the antimicrobial action of cinnamon oil in the range 10-150ug ml-1 showed that 50-fold higher activity was found when no dispersing solvent was used.

This study has shown much greater activity (50-fold more) can be attained with cinnamon oil against S. cerevisiae in the absence of solubilizer. This may be due to the partitioning of the oil between the aqueous phase and DMSO, distancing the oil from the cells. When no DMSO was used, the oil may be solubilized in the lipid membrane of the organism where it can have a greater effect on the cell metabolism.

 

[ermete55]

No, there are patch from old bruise. I'm looking for a way to chelation, dmso is the only way to reach the depth of this stain

What I've been using on bruises is a bit of pure comfrey salve with a few drops of dmso mixed in.

even for hemosiderin stain?

One thing I notice that is used for "bleaching" the skin is niacinamide. Perhaps some capsules of that could be opened and sprinkled in the mix? While the studies I've read talk about it in relation to melanin, it is possible that it would work on other causes. Also doesn't hurt to take niacinamide regularly as suggested in the Iodine Protocol.

https://en.wikipedia.org/wiki/Skin_whitening

Also:

– Niacinamide is the active form of Vitamin B3. A safe, nonirritating cosmeceutical ingredient which research shows can offer a number of benefits in improving the appearance of aged and photodamaged skin and improve skin moisturization.

While its precise mechanism of action is not clear, clinical studies have shown topical niacinamide to be effective in improving skin texture and the appearance of hyperpigmented spots, with improvement in red blotchiness and the reduction of the severity of fine lines.

– It has been shown to stimulate collagen synthesis and production of ceramide, a lipid compound that contributes to the functional and structural integrity of the skin barrier. Theoretically, by improving barrier integrity, niacinamide may help the skin become more resistant to external irritants.

– Topical use of niacinamide has been shown in clinical studies to effectively reduce the rate of sebum excretion and its casual serum levels. http://thesizzlingmommy.com/2015/01/i-just-discovered-that-niacinamide-can-double-as-an-anti-ageing-and-lightening-ingredient.html

http://www.ncbi.nlm.nih.gov/pubmed/12100180

The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.
Hakozaki T1, Minwalla L, Zhuang J, Chhoa M, Matsubara A, Miyamoto K, Greatens A, Hillebrand GG, Bissett DL, Boissy RE.
Author information
Abstract
BACKGROUND:

Cutaneous hyperpigmentation occurs in multiple conditions. In addition, many Asian women desire a lighter skin colour. Thus, there is a need for the development of skin lightening agents. Niacinamide is a possible candidate.
OBJECTIVES:

To investigate the effects of niacinamide on melanogenesis in vitro and on facial hyperpigmentation and skin colour in vivo in Japanese women.
METHODS:

Melanin production was measured in a purified mushroom tyrosinase assay, cultured melanocytes, a keratinocyte/melanocyte coculture model, and a pigmented reconstructed epidermis (PREP) model. The clinical trials included 18 subjects with hyperpigmentation who used 5% niacinamide moisturizer and vehicle moisturizer in a paired design, and 120 subjects with facial tanning who were assigned to two of three treatments: vehicle, sunscreen and 2% niacinamide + sunscreen. Changes in facial hyperpigmentation and skin colour were objectively quantified by computer analysis and visual grading of high-resolution digital images of the face.
RESULTS:

Niacinamide had no effect on the catalytic activity of mushroom tyrosinase or on melanogenesis in cultured melanocytes. However, niacinamide gave 35-68% inhibition of melanosome transfer in the coculture model and reduced cutaneous pigmentation in the PREP model. In the clinical studies, niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use.

CONCLUSIONS:

The data suggest niacinamide is an effective skin lightening compound that works by inhibiting melanosome transfer from melanocytes to keratinocytes.

https://www.oskiaskincare.com/skin-nutrition/patented-actives/niacinamide/

Thnak you Laura. Intersting information about niacinamide.I might try it with dmso Maybe iodine topical with dmso? Iodine is an oxidant so maybe chelate the iron stains...