Essential Oils and dmso: dilution?

  • Thread starter Thread starter ermete55
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lainey said:
I can across another study done on essential oils and DMSO. Antimicrobial Action of Essential Oils: The Effect of Dimethylsulphoxide on the Activity on Cinnamon Oil.
http://www.jonnsaromatherapy.com/pdf/Hili_Antimicrobial_Action_of_Essential_Oils_1997.pdf
Fifty-one essential oils extracted from plants of known origin were tested for their antimicrobial activity against three bacteria, Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli and four yeasts, Torulopsis utilis, Schizosaccharomyces pombe, Candida albicans and Sacccharomyces cerevisiae using the drop diffusion method. All showed antimicrobial activity against at least one of the micro-organisms. Following this preliminary screening, 13 essential oils showing anti-microbial activity against at least five of the micro-organisms were tested in the range 50ug ml-1 to 500ug ml-1 using broth micro dilution techniques with dimethylsulphoxide (DMSO) as a dispersing solvent. The concentration of most of the oils required for total inhibition of growth was >500ug ml-1. Further studies on the antimicrobial action of cinnamon oil in the range 10-150ug ml-1 showed that 50-fold higher activity was found when no dispersing solvent was used.
This study has shown much greater activity (50-fold more) can be attained with cinnamon oil against S. cerevisiae in the absence of solubilizer. This may be due to the partitioning of the oil between the aqueous phase and DMSO, distancing the oil from the cells. When no DMSO was used, the oil may be solubilized in the lipid membrane of the organism where it can have a greater effect on the cell metabolism.
Thank you. Is dangerous or not to use essential oils with dmso? no one knows the answer, that's the problem. Even the scientists do not know the answer.
 
ermete55 said:
Thank you. Is dangerous or not to use essential oils with dmso? no one knows the answer, that's the problem. Even the scientists do not know the answer.

If you have a really good essential oil, I would only use it alone without anything else.

If possible try to use an organic one.
 
Yes, but the essential oil alone don't go enough deep to loose hemosiderin
 
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