High Dose Intravenous Vitamin C (and other vitamin infusions)

About a week ago I had the opportunity to get 50 grams of IV vit C through my doctor's office after showing them the test results for glucose-6-phosphate dehydrogenase. In addition, I have had 2 15 gram doses at 'hydrate' clinics, and one 15 gram done at home over the last year and a half or so. The one physical improvement I can point to with some certainty has been seasonal allergies - as I usually sneeze and sniffle quite a lot come spring and fall. But this year, with only the occasional reaction, things have been pretty ok with no need to take allergy medication.

A little off topic perhaps but I noticed that I didn't feel so wonderful in the few days following this recent treatment. I guess I had some expectations of feeling super-duper afterwards! But then I realized that my smoking shortly before I settle in for reading and going to sleep was not a good habit - as the nicotine tends to make me less likely to sleep a full 7-7:30 hours. And instead, I end up sleeping only 6 hours or so., if that. What a difference a good night's sleep makes, I tell ya!

In any case, this served as a reminder to myself to just continue keeping an eye on the whole picture; we've come to think of the body, and its relative health, as a storehouse or 'bank' that can be added to - or subtracted from - in any number of ways more or less. Doing good things here, and not-so-good things there that can detract from all the work we put into feeling well.
 
I wanted to resurrect this this thread for visibility to may be interest those who haven’t read it.

Last week I started increasing my oral vit c does, titrating to see my tolerance level. I’m taking sodium ascorbate because I used to react really badly with bloating and cramps to ascorbic acid.

I’m up to tolerating 30g a day orally without any real discomfort. Each day it increases which I’m finding interesting, I didn’t expect that to happen. I’m aware this thread is about IV vitamin C which I am looking into and keen to experiment on myself with but I haven’t had the G6PD test done as yet so I’ll experiment orally first.
The things I’ve noticed as a result of this so far short experiment is glowing skin with less fine lines, and significantly less pain around my left hip that has been troubling me for several years. I am somewhat more thirsty but not peeing anymore than usual, just feel a little dehydrated so taking more fluids.

The reason I’m doing the experiment on myself is to see what kind of health improvements I can make before I recommend it to anyone else. I had been researching IV vitamin C in case of emergency (with my youngest two children in mind) and am confident that I can catheter them and give them IV C if they fell too ill to take liquids, intramuscular injections are also another option. But like I said, we all need the blood test first.

p.s.
I wonder whose idea it was to design a body that can’t produce ascorbate on its and has to rely on external sources. Sounds a bit like a cunning plan by the designers to keep us all sick and reliant on medicines to me!!

Also re attaching Dr. Gaby’s article about miraculous vitamin C for those who haven’t read it. It almost sounds too good to be true.
Vitamin C's Historical and Miraculous Record | The Health Matrix
 
Oh and currently in Australia there is a shortage of saline solution bags, so some elective surgeries and clinics offering IV therapies have been put on hold. The government closed down making the solution bags here and now sources them abroad. We were able to go to approved cafes for a latte and get an IV drip of C and other goodies before this happened. Sounds like another nefarious plan to stop people from taking their health into their own hands.
 
A SOTT reader sent us this article. I'm adding it here for the record. It's promising for pancreatic cancer, it would seem. Maybe not a cure in the long run, but useful nonetheless?


Abstract​

Background​

Patients with metastatic pancreatic ductal adenocarcinoma (PDAC) have poor 5-year survival. Pharmacological ascorbate (P-AscH-, high dose, intravenous, vitamin C) has shown promise as an adjunct to chemotherapy. We hypothesized adding P-AscH- to gemcitabine and nab-paclitaxel would increase survival in patients with metastatic PDAC.

Methods​

Patients diagnosed with stage IV pancreatic cancer randomized 1:1 to gemcitabine and nab-paclitaxel only (SOC, control) or to SOC with concomitant P-AscH−, 75 g three times weekly (ASC, investigational). The primary outcome was overall survival with secondary objectives of determining progression-free survival and adverse event incidence. Quality of life and patient reported outcomes for common oncologic symptoms were captured as an exploratory objective. Thirty-six participants were randomized; of this 34 received their assigned study treatment. All analyses were based on data frozen on December 11, 2023.

Results​

Intravenous P-AscH- increased serum ascorbate levels from micromolar to millimolar levels. P-AscH- added to the gemcitabine + nab-paclitaxel (ASC) increased overall survival to 16 months compared to 8.3 months with gemcitabine + nab-paclitaxel (SOC) (HR = 0.46; 90 % CI 0.23, 0.92; p = 0.030). Median progression free survival was 6.2 (ASC) vs. 3.9 months (SOC) (HR = 0.43; 90 % CI 0.20, 0.92; p = 0.029). Adding P-AscH- did not negatively impact quality of life or increase the frequency or severity of adverse events.

Conclusions​

P-AscH− infusions of 75 g three times weekly in patients with metastatic pancreatic cancer prolongs overall and progression free survival without detriment to quality of life or added toxicity (ClinicalTrials.gov
number NCT02905578).
Click to expand...
 
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