About the purpose of not expressing negative emotions:
This makes sense since noradrenaline stimulate living beings to take action:
So what happens if you have a lot of noradrenaline in your brain? Well, it seems that noradrenaline can activate dopamine receptors:
You also have an induction of endogenous MAO inhibitor during the stress:
The rats not allowed to express their aggression had more severe gastric mucosal lesions and a more noticeable and persistent increases in extracelluar NA content in the amygdala determined by intracerebral microdialysis than the rats allowed to express aggression by biting a wooden stick in front of them during stress exposure.
The NA contents in the perfusate were greatly increased in both groups by restraint stress as shown in Fig. 17, but the increases in the non-biting rats were much greater than those in the biting rats. Moreover, although the increases in NA levels in the biting rats rapidly recovered to the baseline values after release from stress, those in the non-biting rats still remained high even after release from stress and a significant difference was still observed 90 min and more after release from stress.
The results suggest that it is important to have an opportunity to express aggression in order to reduce the stress responses.
Emotional Stress and Characteristics of Brain Noradrenaline Release in the Rat
Access full-text academic articles: J-STAGE is an online platform for Japanese academic journals.www.jstage.jst.go.jp
This makes sense since noradrenaline stimulate living beings to take action:
The researchers also found that the neurons that generate this noradrenaline signal appear to send most of their output to the motor cortex, which offers more evidence that this signal stimulates the animals to take action.
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How the brain responds to surprising events
MIT researchers find that one key role of the neuromodulator noradrenaline, produced by the locus coeruleus, is to help the brain learn from surprising outcomes.news.mit.edu
So what happens if you have a lot of noradrenaline in your brain? Well, it seems that noradrenaline can activate dopamine receptors:
Dopamine receptors in the brain are important targets for the therapeutic treatment of psychiatric disorders. Dopamine receptors are generally thought to be activated by dopamine. In the present study, however, we reveal that noradrenaline can also robustly activate dopamine D1 receptors in the mouse hippocampus. Noradrenaline-activated D1 receptor signaling was highly sensitive to the neuronal activity and experience of mice. Chronic stress and voluntary exercise synergistically augmented noradrenaline–D1 receptor signaling. This augmented noradrenaline–D1 receptor signaling promoted the induction of hippocampal neuronal plasticity by an antidepressant drug acting on the noradrenergic system. Our results suggest that noradrenaline–D1 receptor signaling increases the efficacy of antidepressant treatment and therefore can be a unique therapeutic target for augmenting antidepressant medication.
Even though a pure noradrenergic action might not be sufficient to obtain a full antidepressant effect, a pronoradrenergic action represents an important element for increasing the efficacy of mixed action antidepressants.
You also have an induction of endogenous MAO inhibitor during the stress: