Hi everyone,
As I was going through the news tonight, I caught this short article in spanish that I wanted to share with you all, specially given the recent vaccination madness with AstraZeneca in Europe and the mRNA vaccines they're all trying to push forward.
Perhaps I am simply over sensitive to anything that mentions mRNA due to the vaccines, but think about it, Gluten, something we consume via our digestive system, which means it goes through several filters and we're fairly acquainted with, has the ability to alter our mRNA resulting in the development of inflammatory response and disease. Can you imagine what these vaccines, being injected directly into our cells, could do to humanity? specially if it's an already weekend human body?
Here's a link to the article on the Gut journal mentioned, just in case anyone is curious, I haven't checked it out myself: Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells | Gut
As I was going through the news tonight, I caught this short article in spanish that I wanted to share with you all, specially given the recent vaccination madness with AstraZeneca in Europe and the mRNA vaccines they're all trying to push forward.
Celiac disease is a complex autoimmune disorder that affects genetically susceptible individuals. Gluten in the diet triggers an immune response, for which the only treatment available so far is to follow a strict gluten-free diet for life. Following such a diet is not at all easy for patients, as it severely limits their quality of life. The difficulties in following such a strict diet can increase the risk of developing complications such as gastrointestinal cancers, so other treatments are needed to combat this disease. Although it has been proven that certain genes are related to genetic susceptibility to celiac disease, their role in the pathogenesis of the disease remains unknown, making it difficult to develop treatments.
A group from the Department of Genetics, Physical Anthropology and Animal Physiology of the University of the Basque Country (UPV/EHU) has been investigating the development of intestinal inflammation in celiac disease and in cases of gluten intolerance. As explained by Ainara Castellanos-Rubio, an Ikerbasque researcher, important results have been obtained in the study: "On the one hand, we have described for the first time that gluten modifies RNA molecules. These RNA modifications may be related to the development of diseases. Specifically, we have observed that gluten consumption by cells, mice and humans can modify the mRNA (messenger RNA) of the gene called XPO1, resulting in increased production of XPO1 proteins and increased inflammation in the intestine. On the other hand, a genetic variant included in the XPO1 gene has an impact on this RNA modification and increases the risk of developing intestinal inflammation in people with variable risk."
The study is entitled "Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells". It has been published in the journal Gut, one of the most important international journals in gastroenterology and hepatology, which publishes high-level clinical research. This research proposes new alternatives for treating celiac disease and other inflammatory bowel diseases: "Our research has described new therapeutic targets (such as XPO1 and proteins involved in RNA modification), and has opened the possibility of developing new therapeutic approaches to treat celiac disease. We are currently evaluating different molecules targeting these proteins and some are already being used to treat other intestinal diseases," explained Castellanos-Rubio.
On the other hand, and in terms of more basic science, the description of the modification that gluten can cause in RNA "opens new doors for research, since we have seen that external agents (such as gluten in the diet, in this case) can modify our RNA, giving rise to an inflammatory response," she says. In this sense, with a view to a more distant future, the researcher concludes that: "By adapting our diet or using dietary agents we may be able to modify RNA in one way or another, so as to slow down or prevent the development of certain diseases". (Source: UPV/EHU)
Translated with www.DeepL.com/Translator (free version)
Perhaps I am simply over sensitive to anything that mentions mRNA due to the vaccines, but think about it, Gluten, something we consume via our digestive system, which means it goes through several filters and we're fairly acquainted with, has the ability to alter our mRNA resulting in the development of inflammatory response and disease. Can you imagine what these vaccines, being injected directly into our cells, could do to humanity? specially if it's an already weekend human body?
Here's a link to the article on the Gut journal mentioned, just in case anyone is curious, I haven't checked it out myself: Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells | Gut