Low dose Lithium for better mental health

[Persej]

Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by defined factors. The low efficiency of reprogramming and genomic integration of oncogenes and viral vectors limited the potential application of iPSCs. Here we report that Lithium (Li), a drug used to treat mood disorders, greatly enhances iPSC generation from both mouse embryonic fibroblast and human umbilical vein endothelial cells.

Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells - PMC

Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by defined factors. The low efficiency of reprogramming and genomic integration of oncogenes and viral vectors limited the potential application of iPSCs. Here we report ...

pmc.ncbi.nlm.nih.gov

Pluripotent stem cells hold promise in the field of regenerative medicine. Because they can propagate indefinitely, as well as give rise to every other cell type in the body (such as neurons, heart, pancreatic, and liver cells), they represent a single source of cells that could be used to replace those lost to damage or disease.

Since iPSCs can be derived directly from adult tissues, they not only bypass the need for embryos, but can be made in a patient-matched manner, which means that each individual could have their own pluripotent stem cell line. These unlimited supplies of autologous cells could be used to generate transplants without the risk of immune rejection. While the iPSC technology has not yet advanced to a stage where therapeutic transplants have been deemed safe, iPSCs are readily being used in personalized drug discovery efforts and understanding the patient-specific basis of disease.

Induced pluripotent stem cell - Wikipedia

en.wikipedia.org

Another clue to what alchemists were doing with minerals?

 

[RAFL]

On June 18, Dr. Michael Nehls gave a presentation on lithium at the European Parliament. The presentation is in German, but the slides are bilingual in German and English. He demonstrates the essential nature of lithium, the diseases caused by lithium deficiency, and how Big Pharma and others have demonized lithium. This was a historic moment for lithium and especially for Dr. Nehls.

Translated YouTube description of the video:

On June 18, 2025, I had the privilege of giving a historic lecture at the EU Parliament in Strasbourg—a significant moment for me and a first political breakthrough on our shared journey: the recognition of lithium as an essential trace element and its approval for use in dietary supplements.

It is no coincidence that I was able to speak at the heart of European regulatory power, the place where decisions are made about whether we humans have free access to one of the most effective protective factors for our mental and physical immune systems. It is one of the first tangible results of our successful petition “Lithium: Recognition of Essentiality and Approval as a Dietary Supplement.”

This presentation is not only my most recent contribution to this topic, but also my most political. For this occasion, I have fundamentally revised, sharpened, and extensively expanded my slides—as usual, with scientific precision and a clear view of the social and health policy consequences of lithium deficiency.

I was able to demonstrate that lithium is an essential trace element – necessary for our physical health, but above all for our mental health. Without sufficient lithium, the center of our mental immune system, the hippocampus, does not function properly – and neither does our ability to think critically, to be resilient, to change perspectives, and to feel compassion.

A big thank you goes to @report24austria for the raw material. However, this is a 𝗮𝘂𝗳𝘄ä𝗻𝗱𝗶𝗴 ü𝗯𝗲𝗿𝗮𝗿𝗯𝗲𝗶𝘁𝗲𝘁𝗲 𝗻𝗲𝘂𝗲 𝗩𝗲𝗿𝘀𝗶𝗼𝗻, in the 𝗲𝗿𝘀𝘁𝗺𝗮𝗹𝘀 𝗮𝗹𝗹𝗲 𝗴𝗲𝘇𝗲𝗶𝗴𝘁𝗲𝗻 𝗙𝗼𝗹𝗶𝗲𝗻 𝘇𝘂𝗺 𝗯𝗲𝘀𝘀𝗲𝗿𝗲𝗻 𝗡𝗮𝗰𝗵𝘃𝗼𝗹𝗹𝘇𝘂𝗴 𝗲𝗶𝗻𝗴𝗲𝗯𝗹𝗲𝗻𝗱𝗲𝘁 were.
My special thanks go to Mag. Gerald Hauser and Christine Anderson for inviting me to give this presentation.

𝐖𝐚𝐬 𝐒𝐢𝐞 𝐧𝐮𝐧 𝐭𝐮𝐧 𝐤ö𝐧𝐧𝐞𝐧:
This presentation is now publicly available and can be used as a reference. Please make use of it!

Approach your local representatives, doctors, and multipliers. Show them that this topic is scientifically proven, relevant to health, and politically controversial.
And please: help spread this information. Forward the link, post it in your networks, discuss the content. Every single step helps ensure that this knowledge can no longer be ignored.

I would like to thank everyone who made this step possible by supporting the petition. It is a start. But now the decisive phase begins.

 

[Tristan]

Vichy Catalan Water​

Vichy Catalan is a Spanish brand of carbonated mineral water that contains trace amounts of lithium. Specifically, it has 1.3 mg/L of lithium. This mineral water is known for its unique composition, which includes high levels of bicarbonates (2,081 mg/L) and sodium (1,097 mg/L), contributing to its distinctive taste and potential health benefits. The presence of lithium in Vichy Catalan has been noted in various sources, with some studies suggesting that lithium can have neuroprotective properties and may contribute to mental health benefits. Additionally, Vichy Catalan is marketed as having various health benefits, including helping to lower cholesterol, promoting digestion, and providing rehydration after physical activity. The water is sourced from the thermal springs in Caldes de Malavella, Girona, and has a long history dating back to its establishment in 1881.

Studies have shown that lithium can inhibit the enzyme GSK-3, which is responsible for neuronal death, thereby offering protection against brain aging. Some studies also report other benefits of consuming this water due to its composition.

The lithium content in Vichy Catalan is approximately 1.3 mg/L, and consuming one liter of this water provides 1300 micrograms of lithium, which is considered to cover the basic needs of the body and potentially offer protection against neuronal degeneration. Additionally, the water has been associated with cardiovascular benefits, including the reduction of LDL ("bad") cholesterol levels.

The CSIC (Consejo Superior de Investigaciones Científicas) has conducted studies on the effects of Vichy Catalan, indicating that it may help lower LDL cholesterol and improve cardiovascular risk biomarkers in healthy adults. However, it is important to note that the lithium doses used for mental health treatment are considerably higher than those obtained from daily exposure to lithium in tap water or from Vichy Catalan.

://finewaters.com/bottled-waters-of-the-world/spain/vichy-catalan

Lithium-Rich Mineral Water is a Highly Bioavailable Lithium Source for Human Consumption - PubMed

Lithium-rich mineral and medicinal waters may be an important and highly bioavailable lithium source for human consumption.

pubmed.ncbi.nlm.nih.gov

Conclusion: Lithium-rich mineral and medicinal waters may be an important and highly bioavailable lithium source for human consumption.

Lithium concentration in tap water, bottled mineral water, and Danube River water in Hungary - Scientific Reports

Due to increased manufacture and recycling of lithium batteries across the world, we may anticipate a rise in lithium pollution in the aquatic environment and drinking water reservoirs. In order to investigate the current status regarding the lithium content in Hungarian tap waters, samples were...

www.nature.com

Conclusion​

If we accept Schrauzer’s assertion that the dietary allowance for Li is 1 mg/day and the finding that drinking water contains Li on average at concentration of 5 µg/L, then based on the measured Li concentration in Hungary, it can be deduced that when we consume daily 2 L of drinking water, we only take one-hundreds of the daily requirements. If we also consider the mineral water consumption in Hungary, the daily intake of Li from tap water and mineral water amounts to only ~ 26 µg/capita, which is less than 3% of dietary allowance. Although the highest increment in Li concentration caused by Li-battery production and recycling of spent batteries can be expected in drinking water produced from bank filtrated Danube water, this does not result in substantial change in the daily intake of the affected population. It means the dietary allowance of Li should be covered from different plant-based foods (cereals, tomatoes, potatoes, cabbage) which contain Li in a less bioavailable chemical form<a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" title="Seidel, U. et al. Lithium-rich mineral water is a highly bioavailable lithium source for human consumption. Mol. Nutr. Food Res. 63, 1900039. https://doi.org/10.1002/mnfr.201900039 (2019)." href="Lithium concentration in tap water, bottled mineral water, and Danube River water in Hungary - Scientific Reports">39</a>. It should be noted that measured Li concentrations related to the Danube water serve as background values for evaluation of the expected Li contamination of the aquatic environment.

Here is a comparative publication on Portuguese water brands regarding this topic.

Lithium in Portuguese Bottled Natural Mineral Waters—Potential for Health Benefits? - PMC

There is increasing epidemiologic and experimental evidence that lithium (Li) exhibits significant health benefits, even at concentrations lower than the therapeutic oral doses prescribed as treatment for mental disorders. The aim of this study is ...

pmc.ncbi.nlm.nih.gov

Conclusions​

Depending on the chemical composition, natural mineral waters may significantly contribute to the recommended daily intake of minerals and provide us with a natural source of healthy hydration.
The health effects of Li in drinking water, both tap waters and bottled waters is not fully understood yet but there are indications that natural moderately high Li contents may be beneficial to the mental health situation of the population. In the present study the Li content from a set of bottled natural mineral waters from Portugal was evaluated. Based in the Li content two sets of natural mineral waters could be recognized. A set with low Li concentrations (up to 11 μg/L) that will not have any different effects on the dietary Li supply as compared to the contribution of tap water to the dietary contribution of Li and a second set with higher Li concentrations (173 to 2210 μg/L). The natural mineral water with higher Li contents (>1500 μg/L) is highly mineralized, mostly Na-HCO3 type waters and naturally carbonated (CO2-rich waters with > 250 mg/L free CO2). These Li-rich natural mineral waters can be a source of bioavailable Li and its consumption cannot be ignored in studies evaluating the intake of natural doses of Li via drinking water or diet. It thus is important to take into consideration for studies towards Li health effects or benefits for the population or at an individual level. Among the studied bottled natural mineral waters, the consumption of 0.25 L/day of Vidago natural mineral water can contribute significantly to reach the proposed provisional Li daily intake.
It should be noted that the dose of Li ingested through bottled natural mineral water is significantly less than the recommended doses for therapeutic purposes and for that reason these waters can be also regarded as a natural nutritional supplement.
Lithium’s interaction in human biochemistry is complex and should be a subject for continuous research to demonstrate the possible clinical effects of natural low-dose Li intake on mental health of the public.

 

[JEEP]

Contributing to this thread due to recent information discovered about lithium orotate. I actually began taking low dose lithium after reading this article on Sott:

Lithium: The untold story of the magic mineral

As far as cosmologists can tell, there were only three elements present when the universe was first formed some 13.8 billion years ago: hydrogen, helium, and lithium. As one of the three original elements, lithium is found throughout our...

www.sott.net

Interestingly enough, because I couldn't at first remember where this article was, I discovered new info that indicates a better form of lithium, lithium orotate. That Sott article mostly advocated low dose lithium and only mentioned lithium orotate once. Here's where I got the newer information with a youtube vid about Dr. Mark Millar, The Lithium Doctor:

92: Dr. Mark Millar, D.C. – The Lithium Doctor - Living Wealthy Radio

Post traumatic stress disorder and depression are just a couple of the psychological diseases in our country with incidence rates that are increasing. We hear warnings about the dangerous side effects of the drugs used to treat these illnesses, but we don't hear of any changes being made by...

livingwealthyradio.com

I viewed the youtube vid and learned of Dr. Millar's very interesting back story. The fact that our soil is very depleted of lithium corresponds with the rise of suicide and depression in this country. The addition of orotate makes the lithium bioavailable in a way regular psychiatric prescribed lithium carbonate isn't and the difference takes something very toxic to harmless and beneficial. Even small children can safely take this natural supplement with parents ecstatic at the results. It truly sounds like the answer to the huge mental health crisis plaguing modern society. It's pointed out that alcohol and marijuana are often used to self-medicate for the lack of lithium in the body with the resulting detrimental effects upon the individual, family, and social interactions. Anxiety and migraines are among the conditions this supplement can successfully treat in addition to PTSD, bi-polar, depression, suicide ideation, alzheimers, and alcoholism while increasing cognitive enhancement and mood regulation. All this with really no downside as long as dose levels are appropriate. Plus, it's inexpensive. A win-win all around.

Dr. Millar has authored the book, The Natural Mental Health Breakthrough: Achieve Mental and Physical Well-Being with Lithium Orotate. In it, the following is noted:

Published studies have shown that Lithium Orotate can benefit over 150 diseases, conditions, or symptoms. Here is just a short list.

1. ADD & ADHD
2. Alcoholism & drug addictions
3. Alzheimer’s
4. Anorexia Nervosa
5. Bulimia Nervosa
6. Antisocial behavior
7. Anxiety disorders (all types)
8. Autism
9. Asperger's
10. Bipolar disorder
11. Borderline Personality disorder
12. Bruxism
13. Concussion/Closed head injuries
14. Depression (all types)
15. Drug addiction & withdrawal
16. Epilepsy
17. Fibromyalgia
18. Headaches (all types)
19. Hyperthyroidism
20. Insomnia
21. Irritability
22. Lyme disease
23. Nightmares
24. Obsessive Compulsive disorder
25. Panic disorder
26. Parkinson’s disease
27. Pathological gambling
28. Post-Traumatic Stress disorder
29. Restless Leg syndrome
30. Schizoaffective disorder
31. Schizophrenia
32. Sleep disorders
33. Social Anxiety/Phobia
34. Stroke recovery
35. Tourette’s syndrome
36. Ulcers
37. Violent behavior

Here is additional info on the subject:

Lithium Orotate Benefits for Your Brain and Beyond

Source: Lithium Orotate Benefits for Your Brain and Beyond by Dr. Edward Group In the early 1900s, people flocked to Lithia Springs in Georgia, a hot spring known for its lithium-enriched water. Ha…

dreddymd.com

In his Substack newsletter, Nehls further explained that microdosing lithium can reduce the risk of entering a life-threatening cycle. Said cycle is the long-term dysfunction of the hippocampus, a complex brain structure embedded deep into the temporal lobe that plays a major role in learning and memory, leads to reduced psychological resilience, which triggers an excessive and chronic stress response, which in turn over activates the brain's immune system and leads to an increased and particularly persistent release of pro-inflammatory messengers.

Lithium: The little-known element that can protect people from brainwashing by global elites, says researcher, author and medical doctor – NaturalNews.com

For experts such as Dr. Michael Nehls, a world-renowned author, medical doctor and post-doctoral molecular geneticist, the globalist anti-human agenda is being rolled out via a warfare inside human brains – hijacking cognitively to influence and disrupt both the mental and physical immune...

www.naturalnews.com

Thanks to orotic acid, Dr. Gray and others claim, we can get all the lithium our brains need by taking lithium orotate in very small doses.​

Despite these claims, however, very little research has been done on lithium orotate.

Perhaps the most known study was done all the way back in 1986, when researchers tested the long-term effects of lithium orotate on recovering alcoholics. The results were that not one of the 42 patients studied had a relapse for six months following the treatment, and ten of the patients had no relapse for over three and up to ten years.

Some of the patients did develop minor side effects, but these disappeared when the dosage of lithium orotate (which started out much higher than Dr. Gray currently recommends, at 150 mg. per day) was reduced. The researchers concluded that lithium orotate is effective for the treatment of alcoholism.

Dr. Gray's hypothesis is that research has not been done because pharmaceutical companies wouldn't make much money from it. Lithium orotate is not a prescription drug, but a natural supplement that anyone can buy cheaply over the counter.

Pharmaceutical companies are making a pretty penny getting doctors to prescribe toxic doses of lithium carbonate to desperate mentally ill patients, so why tell them there's actually a cheaper, safer alternative?
Lithium orotate: Can this naturally occurring alkali metal cure your mental woes? - NaturalNews.com

Lithium orotate in the treatment of alcoholism and related conditions.
NCBI - WWW Error Blocked Diagnostic

Lithium occurs naturally in some waters with positive effects on the local population. Contrast that with our government fluoridated water practically nationwide along with our lithium depleted soils. A boon for the pharmaceutical industry to the max.

 

[YoYa]

Lithium gave me my life back. For about 30 months, I felt like I was switched off. I could barely manage my household, lacked motivation, and felt frozen inside.

Since lithium is only available by prescription in Switzerland, Austria, and Germany, I initially consumed it through my drinking water. One 0.75-liter bottle of Hirschquelle contains 1.31 mg of lithium.

I now take 5 mg of lithium orotate.

My experience with lithium has been consistently positive. My problems haven't disappeared, but I'm tackling them.

Lithium hat mir buchstäblich das Leben zurückgegeben. Gut 30 Monate lang war ich wie ausgeschaltet - ich konnte kaum meinen Haushalt bewältigen, hatte keinerlei Motivation und fühlte mich innerlich wie eingefroren.
Da Lithium in der Schweiz, Österreich und Deutschland rezeptpflichtig ist, habe ich es zunächst über das Trinkwasser zu mir genommen. Eine Flasche Hirschquelle (0,75L) enthält 1,31mg Lithium.
Inzwischen nehme ich Lithium-Orotat in der Dosierung von 5mg.
Meine Erfahrung mit Lithium ist durchweg positiv.
Nicht dass meine Probleme verschwunden wären, aber ich gehe sie an.

 

[ScioAgapeOmnis]

Contributing to this thread due to recent information discovered about lithium orotate. I actually began taking low dose lithium after reading this article on Sott:

Lithium: The untold story of the magic mineral

As far as cosmologists can tell, there were only three elements present when the universe was first formed some 13.8 billion years ago: hydrogen, helium, and lithium. As one of the three original elements, lithium is found throughout our...

www.sott.net

Interestingly enough, because I couldn't at first remember where this article was, I discovered new info that indicates a better form of lithium, lithium orotate. That Sott article mostly advocated low dose lithium and only mentioned lithium orotate once. Here's where I got the newer information with a youtube vid about Dr. Mark Millar, The Lithium Doctor:

92: Dr. Mark Millar, D.C. – The Lithium Doctor - Living Wealthy Radio

Post traumatic stress disorder and depression are just a couple of the psychological diseases in our country with incidence rates that are increasing. We hear warnings about the dangerous side effects of the drugs used to treat these illnesses, but we don't hear of any changes being made by...

livingwealthyradio.com

I viewed the youtube vid and learned of Dr. Millar's very interesting back story. The fact that our soil is very depleted of lithium corresponds with the rise of suicide and depression in this country. The addition of orotate makes the lithium bioavailable in a way regular psychiatric prescribed lithium carbonate isn't and the difference takes something very toxic to harmless and beneficial. Even small children can safely take this natural supplement with parents ecstatic at the results. It truly sounds like the answer to the huge mental health crisis plaguing modern society. It's pointed out that alcohol and marijuana are often used to self-medicate for the lack of lithium in the body with the resulting detrimental effects upon the individual, family, and social interactions. Anxiety and migraines are among the conditions this supplement can successfully treat in addition to PTSD, bi-polar, depression, suicide ideation, alzheimers, and alcoholism while increasing cognitive enhancement and mood regulation. All this with really no downside as long as dose levels are appropriate. Plus, it's inexpensive. A win-win all around.

Dr. Millar has authored the book, The Natural Mental Health Breakthrough: Achieve Mental and Physical Well-Being with Lithium Orotate. In it, the following is noted:

Published studies have shown that Lithium Orotate can benefit over 150 diseases, conditions, or symptoms. Here is just a short list.

1. ADD & ADHD
2. Alcoholism & drug addictions
3. Alzheimer’s
4. Anorexia Nervosa
5. Bulimia Nervosa
6. Antisocial behavior
7. Anxiety disorders (all types)
8. Autism
9. Asperger's
10. Bipolar disorder
11. Borderline Personality disorder
12. Bruxism
13. Concussion/Closed head injuries
14. Depression (all types)
15. Drug addiction & withdrawal
16. Epilepsy
17. Fibromyalgia
18. Headaches (all types)
19. Hyperthyroidism
20. Insomnia
21. Irritability
22. Lyme disease
23. Nightmares
24. Obsessive Compulsive disorder
25. Panic disorder
26. Parkinson’s disease
27. Pathological gambling
28. Post-Traumatic Stress disorder
29. Restless Leg syndrome
30. Schizoaffective disorder
31. Schizophrenia
32. Sleep disorders
33. Social Anxiety/Phobia
34. Stroke recovery
35. Tourette’s syndrome
36. Ulcers
37. Violent behavior

Here is additional info on the subject:

Lithium Orotate Benefits for Your Brain and Beyond

Source: Lithium Orotate Benefits for Your Brain and Beyond by Dr. Edward Group In the early 1900s, people flocked to Lithia Springs in Georgia, a hot spring known for its lithium-enriched water. Ha…

dreddymd.com

Lithium orotate in the treatment of alcoholism and related conditions.
NCBI - WWW Error Blocked Diagnostic

Lithium occurs naturally in some waters with positive effects on the local population. Contrast that with our government fluoridated water practically nationwide along with our lithium depleted soils. A boon for the pharmaceutical industry to the max.

And just for ease of reading, I had an AI categorize them:

1. Mood & Affective Disorders
Conditions primarily involving mood dysregulation, emotional instability, or depressive states.

• Bipolar disorder
• Depression (all types)
• Anxiety disorders (all types)
• Panic disorder
• Obsessive Compulsive disorder
• Post-Traumatic Stress disorder
• Schizoaffective disorder
• Schizophrenia
• Social Anxiety/Phobia
• Irritability

2. Neurodevelopmental & Neurobehavioral Disorders
Conditions involving early brain development, behavioral regulation, or neurodivergence.

• ADD & ADHD
• Autism
• Asperger's
• Antisocial behavior
• Tourette’s syndrome
• Violent behavior
• Pathological gambling

3. Neurodegenerative & Neurological Conditions
Progressive brain disorders or brain injuries affecting structure and function.

• Alzheimer’s
• Parkinson’s disease
• Stroke recovery
• Concussion / Closed head injuries
• Epilepsy

4. Chronic Pain & Systemic Conditions
Conditions involving physical pain, inflammation, or systemic dysfunction.

• Fibromyalgia
• Headaches (all types)
• Restless Leg syndrome
• Ulcers
• Hyperthyroidism
• Lyme disease

5. Substance Use & Behavioral Addictions
Addictions involving compulsive behavior and reward pathway dysregulation.

• Alcoholism & drug addictions
• Drug addiction & withdrawal
• Pathological gambling

6. Sleep & Circadian Disorders
Conditions primarily affecting sleep architecture or regulation.

• Insomnia
• Nightmares
• Sleep disorders

7. Eating Disorders
Disorders characterized by abnormal eating behaviors and body image distortion.

• Anorexia Nervosa
• Bulimia Nervosa

8. Psychiatric Symptoms & Behavioral Manifestations
Symptoms that cut across multiple disorders but are not standalone diagnoses.

• Bruxism

 

[RedFox]

Just adding to this, something I saw yesterday:

New hope for Alzheimer’s: lithium supplement reverses memory loss in mice

Studies in rodents and humans suggest that low levels of the metal contribute to cognitive decline.

www.nature.com

Replenishing the brain’s natural stores of lithium can protect against and even reverse Alzheimer’s disease, suggests a paper published today in Nature.

Here’s the paper referenced (they used lithium orotate)

Lithium deficiency and the onset of Alzheimer’s disease - Nature

Lithium has an essential role in the brain and is deficient early in Alzheimer’s disease, which can be recapitulated in mice and treated with a novel lithium salt that restores the physiological level.

www.nature.com