N-back game, Fluid Intelligence, Working Memory

monotonic said:
[...]
I'm sorry for the bother. I think I had the impression that you are not open to the possibility of N-back being beneficial.

No bother at all. I'm open to all possibilities as far as I know. It's kinda hard to discuss something without 'coming from' somewhere though and giving an impression of closed-mindedness at times. If that's how my posts appear, I'll be happy to address that because I've often abandoned a position when I see evidence to do so.


As for my method, the modified form of mindfulness I use simply means I don't try to erase or edit anything from my field of 'view'. It involves a non-judgmental acceptance of whatever I perceive in an effort to keep my presence totally in the moment.

The benefit is that my attention doesn't get involuntarily sucked into negative feedback loops that get stimulated by environmental cues. Cues that may have an emotional significance to me that I am currently unaware of. That's all.

How is this different from your state of mind ordinarily?

Ordinarily, before exposure to the Work, I'd be more of a reaction machine, exercising little or no control over my responses to everything that effects me emotionally, especially if I must constantly be stressed out dealing with the zombification all around us. And where/when I couldn't keep busy or find some peace, my mind would be in overdrive, fueling my negative thought loops and looking for a way out without getting to the bottom of my reactions to try and understand on deeper and deeper levels. My job-hopping history speaks to that as well as the boredom problem.

I wasn't just 'ADD'. As a result of my early life experiences, I also had that narcissistic (me vs. all them) split. I thought my birth into the world was some kind of cruel joke and I resented it. Intensely.


Isn't it programs and identification which cause a person to be not mindful?

This may be just semantics, but maybe it depends on what we consider the 'first condition'. If we see that a young child starts out 'mindful', then programming and identifications may be the cause to be not mindful. If we start Mindfulness after having been ponerized, then I'd say the 'cause' of being not mindful is lack of self-discipline which the Mindfulness can help with. I reckon the proof is that programs and identifications can remain in the presence of the Mindful state.

If you can't be mindful while busy how can you be mindful while in any other state?

I would say you can't. If I gave that impression, it was unintentional, sorry.
 
Bud said:
If you really are 'ADHD', then you are probably undermining the automatic associative activity that does relationship discovery, pattern matching and pattern recognition in your flexible, normal state of mind.
Actually, this is precisely the ability this task improves (fluid intelligence).

Indeed, according to a 2009 article in Science magazine, '14 hours of training over 5 weeks' has led to an increase in cortical dopamine receptors. Now, hike up the stress levels, squirt out more dopamine for those receptors and before you know it, you might be 'stuck' in that state for quite awhile, if not forever.
I don't understand what you are implying here, or whether you are asserting anything based on evidence. ADHD has been found to be associated with lower levels of dopamine receptors.

In my experience, this is not how fluid intelligence is actually enhanced - quite the reverse, actually. The lower the stress, the easier learning is - that is, with an understanding-based (not rote-based) memory.
This game is designed to increase working memory, or the ability to hold several pieces of relevant information in the mind to aid in the solving of complex problems. A good example of a working memory-intensive task is writing a novel, where one has to remember the interplay of character personalities and relationships to develop a convincing and interesting plot. Fluid intelligence (Gf) is the ability to solve novel problems (i.e problems that do not draw on prior knowledge for their solution), and working memory is thought to be a major component of this type of intelligence. Training in dual n-back has shown increases in measures of Gf, reading comprehension, etc., with no negative effects that I am aware of, so if you are interested in increasing these types of abilities I would encourage you to try the game. Here is a really good FAQ related to working memory and dual N-back.
 
Kesdjan said:
Bud said:
If you really are 'ADHD', then you are probably undermining the automatic associative activity that does relationship discovery, pattern matching and pattern recognition in your flexible, normal state of mind.
Actually, this is precisely the ability this task improves (fluid intelligence).

Sez who? Raymond Cattell? Seems to me Cattell blurs the line between the inductive and deductive faculties. He conceptualizes fluid intelligence and crystallized intelligence as being mutually exclusive, assigning previous learning to the crystallized 'side' while lumping inductive and deductive reasoning together as 'fluid intelligence'. To me, deductive thinking has to include the knowledge in the crystallized part, requiring his two separate parts to overlap, at least.

Have you ever tried to work out an algebra problem in your head while noticing the relationship between 3 cars in a parking lot that explains why one of them is backing around a corner towards your front fender? What I get from Cattell is that "yes, you should be able to since its all the same".

Gf only makes sense to me if you use the phrase 'fluid reasoning'. Which to me is an active process not synonymous with 'fluid intelligence' which seems to imply a more static state despite the word 'fluid'.

Then there's those tests. Anyone with ADHD knows the difficulties associated with standardized tests. The most commonly used measures of fluid intelligence is the non-verbal multiple choice. Why non-verbal? For me and others I know, 'talking it out' seems to help keep the inductive thought process blended with the inductive awareness when one knows what one is talking about. For someone with ADHD, constraining the test by requiring the subject to 'Go Inside' the mind, in the midst of all the 'noise' makes it extremely difficult and requires a hyperfocus state that usually only lasts until interest is over, the stimulant helpers get cleaned up, or the brain chemistry were to balance itself in that state. This comes from my experience, the experience of family members with ADHD and these folks:

Messick, S. (1989). Meaning and values in test validation: The science and ethics of assessment. Educational Researcher, 18, 5–11. Messick, S. (1995). Validity of psychological assessment. American Psychologist, 50, 741–749.

...and others. And that is why I was asking about interest level. Why would I want to train my hyper-focus state?


Kesdjan said:
Indeed, according to a 2009 article in Science magazine, '14 hours of training over 5 weeks' has led to an increase in cortical dopamine receptors. Now, hike up the stress levels, squirt out more dopamine for those receptors and before you know it, you might be 'stuck' in that state for quite awhile, if not forever.
I don't understand what you are implying here, or whether you are asserting anything based on evidence.

If I was implying anything it would have been based on the knowledge that a person with a sustained focus on, and repetitive activity with, anything - from cocaine to N-Back to W.O.W is just as prone to a state they will come to feel as an addiction at some point in time. I'm assuming you've read The Wave chapter on addiction? There is a strong relationship between stress and addiction and this chapter is just as applicable.

Laura's first EE audio program mentions the high prevalence of stress in society. The size of the study group at Yale indicates the relationship:

_http://www.medicineatyale.org/v3i5_sept_oct_2007/stress_addiction.html

...and some people explicitly recognize that stress is addictive, as described in the 1983 New York Times article on Stress Addiction:

_http://query.nytimes.com/gst/fullpage.html?res=9C02E0D81339F935A15754C0A965948260&sec=health&spon=&pagewanted=1

And probably any addict will admit that an episode of increased stress can trigger relapse in their recovering process. It’s not hard to see how this might be so, because addictive drugs work by releasing dopamine, and so does stress!

But this implication, such as it is, is based only on a read of the first posts on the thread. A fact I indicated in my first response. And at the time, I was still curious about monotonic's ADHD status and I figured it was going to somehow make a difference to my attitude towards the game.


Kesdjan said:
ADHD has been found to be associated with lower levels of dopamine receptors.

Kesdjan, I'm just curious. Did you not read my post that mentions Barkley and the ADHD-dopamine connection?


In my experience, this is not how fluid intelligence is actually enhanced - quite the reverse, actually. The lower the stress, the easier learning is - that is, with an understanding-based (not rote-based) memory.
This game is designed to increase working memory, or the ability to hold several pieces of relevant information in the mind to aid in the solving of complex problems. A good example of a working memory-intensive task is writing a novel, where one has to remember the interplay of character personalities and relationships to develop a convincing and interesting plot. Fluid intelligence (Gf) is the ability to solve novel problems (i.e problems that do not draw on prior knowledge for their solution), and working memory is thought to be a major component of this type of intelligence. Training in dual n-back has shown increases in measures of Gf, reading comprehension, etc., with no negative effects that I am aware of, so if you are interested in increasing these types of abilities I would encourage you to try the game. Here is a really good FAQ related to working memory and dual N-back.

I may have a different understanding of working memory and that's fine, I suppose. My working memory is flexible and the only problem I've ever had using it or filling it the way you mention, has nothing to do with natural limitations or the ability to hold it in the face of routine distractions and interferences. It has to do with stress of certain types. Mainly negativity. Internal (from negative thought loops which Mindfulness helps with) and external. Harassment or coercive demands can blow it, just like it can the inductive faculty, albeit temporarily. How temporary depends on how long it continues.

After awhile of this, some of us experience aversion therapy and might go a whole week without being creatively productive at all and not even realize why. Because for some, the faculty they use to notice the differences is temporarily missing! Ask any creative software engineer or computer programmer or poet or creative artist about this, since this faculty is their livelihood.



---------------------------
Edit: additions for clarity
 
Bud, it seems like you may be responding somewhat reflexively in your posts on this subject. Your opposition seems to be based around several primary arguments, which I will try to address below, with quotes.
NOTE: it seems I went off in another direction than my original intent. At the bottom of the post is a summary. If it seems appropriate, I will continue with the original intent of this post at a later time in the discussion.

Bud said:
From what I do see, you are training yourself to stay in hyper-focused mode for longer and longer periods of time.
[...]
In my experience, this is not how fluid intelligence is actually enhanced - quite the reverse, actually. The lower the stress, the easier learning is - that is, with an understanding-based (not rote-based) memory.
As an intensive concentration/awareness exercise, it is possible N-back may produce some stress during the activity, as will any intensive task. However, you seem to be implying that N-back will produce a stressed state outside of the exercise, and I don't see why this would be true. Physical exercise produces a bodily stress response, yet this does not mean a person will be more stressed in their life because they exercise!

Bud said:
Indeed, according to a 2009 article in Science magazine, '14 hours of training over 5 weeks' has led to an increase in cortical dopamine receptors. Now, hike up the stress levels, squirt out more dopamine for those receptors and before you know it, you might be 'stuck' in that state for quite awhile, if not forever. Smiley
You really seem to be taking a stance that more dopamine receptors is a "bad" thing. How well do you understand the workings of dopamine and its receptors on the body and mind? Firstly I must say that as a neurotransmitter, certainly dopamine is important, and having proper levels and a proper number of receptors must thus be important for the organism's well-being. Neurotransmitters are one way the body communicates with itself, and in general it seems rational that to increase the body's ability to communicate internally would improve organism functioning. I have done some quick research and found the following:

_http://www.wisegeek.com/what-are-dopamine-receptors.htm
"Dopamine receptors are one class or type of receptors that are found in the central nervous system as well as other key points near nerve endings in various organs. The receptors are instrumental in the proper function of the neurotransmitter dopamine, which has a significant effect on the function of the nervous system in regard to memory, general mood, and cognition. When the supply of dopamine to the receptors is inhibited in some manner, an individual may be begin to experience difficulty concentrating, become easily irritated, and possibly become severely depressed
[...]
This means that someone who is currently dealing with unusual periods of irritation or depression may find that taking a dopamine agonist will alleviate those symptoms and restore a more balanced frame of mind.
[...]
Using replacement therapy to help feed the dopamine receptors can quickly reverse the situation and help the individual cope until the origins of the stress are addressed and resolved.
"

Now, firstly I must qualify some of what I said above. Your reply to Kesdjan directed me to see what you were referring to about dopamine receptors:
Bud said:
It's my current understanding that the symptoms/results collected from numbers 1-3 are usually compared to the published findings of Dr. Russell Barkley, whose work with people in the 1990's led to his 1998 'revelation' of the polymorphic DRD4 receptor gene that produces a 'defective' receptor that cannot bind with the corresponding dopamine molecule. Also noted was the R7 DAT alle which causes the uptake pumps, or 'clean up' mechanism to pick up and recycle the molecules before many of them have a chance to bind with receptors.
So if the trouble is with faulty receptors, maybe increasing the number of receptors could be a problem, and the above text might not apply in this special case. If the number of receptors is increasing despite their "faultiness", might this imply that they are doing something, possibly beneficial or harmful? We can consider the possibility that in these people the dopamine receptors work somewhat differently, without necessarily being harmful (although we cannot assume this, either). If these receptors are not binding dopamine at all, and the body has mechanisms for ridding itself of excess, then it seems to me that increased receptors would not be a problem; although I'm sure the matter is more complex than this. I didn't manage to turn up any info on the nature of this, although I did find this page that links to info about DRD4 and other genes related to ADD/ADHD; _http://adhd-treatment-options.blogspot.com/2008/08/adhd-treatment-options_31.html .

In any case, it might help if you would provide more evidence that a higher dopamine receptor count might have a degenerative effect on total reasoning ability. Note that some of the above writing before I reread the part about receptors wasn't taking the full information into account, which I recognize. I leave it there as information, for what it's worth. In any case, for the purpose of drawing together information that is relevant, I'll post some further quotes from information I discovered.

_http://borntoexplore.org/neurochem.htm
"Reduced dopamine/norepinephrine caused by boring surroundings and lack of exercise may manifest as ADD, impulsivity, lack of concentration, restlessness, and depression or loss of pleasure. Dopamine is the "feel good" chemical which illegal drugs mimic (such as cocaine, heroin, marijuana) as well as cigarettes, coffee and alcohol. Ritalin and other ADD drugs are thought to increase dopamine activity."

I read elsewhere that these substances actually produce a dopamine spike, as well as imitate it.

_http://adhd-treatment-options.blogspot.com/2008/09/adhd-gene4-dopamine-beta-hydroxylase.html
"What makes this DBH such an interesting gene associated with ADHD is the fact that several diseases or disorders that are often comorbid (existing alongside of or with) ADHD also have ties to this gene. Among them are smoking (both in tendency to smoke and the number of cigarettes smoked per day) and suceptibility to migraine headaches. Additionally, there is a suggested genetic linkage between a particular form (allele) of this DBH gene and a built-in resistance to Parkinson's disease. Of somewhat interest is the fact individuals with ADHD are statistically more susceptible to contracting Parkinson's later in life than the rest of the general population."

_https://secure.wikimedia.org/wikipedia/en/wiki/Parkinson%27s_disease
"Parkinson's disease (also known as Parkinson's, Parkinson disease, or PD) is a degenerative disorder of the central nervous system that impairs motor skills, cognitive processes, and other functions.
[...]
Symptoms result from insufficient formation and action of dopamine produced in the dopaminergic neurons of the midbrain (specifically the substantia nigra).
[...]
The primary symptoms of Parkinson's disease result from greatly reduced activity of dopamine-secreting cells due to cell death in the pars compacta region of the substantia nigra.
"

The connection with Parkinson's is interesting. Low Dopamine has some serious effects, which makes me skeptical that dopamine receptors are entirely rejecting dopamine in people with that genetic trait, considering that they tend to be reasonably healthy on average.

_http://www.eurekalert.org/pub_releases/2009-04/uowo-cob042009.php
"Lauzon, a Doctoral graduate student in the Laviolette laboratory, discovered that specific receptors for the neurotransmitter dopamine can control how the brain processes emotionally significant information as well as memories for those experiences. Using a rodent model of emotional learning and memory formation, the researchers found by increasing the activity of a specific dopamine receptor in a region of the brain called the prefrontal cortex, it was able to transform a normally insignificant emotional experience into a very strong emotional memory. In contrast, when a different subtype of the dopamine system was activated, it was able to block the ability to recall an emotionally charged experience."

Okay, from this I gather that there are multiple types of dopamine receptor which have different influences on memory, related to emotionally charged events. If there are multiple types, then a genetic malformation or uniqueness probably doesn't inhibit all of them. In this case, increased levels of receptors may be desirable because at least the healthy receptors may be increased as part of the overall increase. On a different line, if the altered dopamine receptors are not non-functional but less-functional, having increased numbers may allow an ADD/ADHD person to approach normal levels of dopamine response, possibly reducing depression and other symptoms. Only a thought.

_http://www.mcmanweb.com/dopamine.html
"Yes, serotonin is the neurotransmitter we tend to think of when it comes to depression, but, as the authors point out, a large number of animal studies, plus gene research and neuroimaging on humans and other findings "support the hypothesis that major depression is associated with a state of reduced dopamine transmission."
[...]
[...]"anhedonia, the absolute or relative inability to experience pleasure, is one of two symptoms required for the diagnosis of major depression." Anhedonia is universally regarded as a "core" symptom of depression. It is well-established that dopamine plays a central role in the brain’s reward system, which includes inducing feelings of pleasure and positive mood states.
"

_http://ajp.psychiatryonline.org/cgi/content/full/158/12/2015
"A consistent finding in drug-addicted subjects is a lower level of dopamine D2 receptors. In cocaine abusers, low levels of D2 receptors are associated with a lower level of metabolism in the orbitofrontal cortex. Because the orbitofrontal cortex is associated with compulsive behaviors, its disruption may contribute to compulsive drug intake in addicted subjects."

This is especially interesting, as this could indicate that increased numbers of dopamine receptors may decrease one's risk of addictive behaviors.

_http://www.carrotofhope.org/ptsd_catecholamines.html
"Dopamine, like the other two catecholamines, also increases heart rate and blood pressure. However it's effects on mood are the most pronounced. Dopamine affects cognition, motivation, competition, sexual arousal, awareness, alertness, sleep, motor activity, attention, and learning. While elevated levels can be useful, once dopamine becomes imbalanced by being overstimulated with post traumtic stress syndrome, the hyperaroused individual can be unsafe. Elevated levels of dopamine explain why PTSD often leads to acts of violence against one's self or others."

Note that PTSD does not solely consist of elevated dopamine, but also chronic, elevated levels of other neurotranmitters (more info on the website, of course).

_https://secure.wikimedia.org/wikipedia/en/wiki/Dopamine#Dopaminergic_mind_hypothesis
"High levels of dopamine are proposed to underlie increased psychological disorders in industrialized societies. According to this hypothesis, a "dopaminergic society" is an extremely goal-oriented, fast-paced, and even manic society, "given that dopamine is known to increase activity levels, speed up our internal clocks and create a preference for novel over unchanging environments." In the same way that high-dopamine individuals lack empathy and exhibit a more masculine behavioral style, dopaminergic societies are "typified by more conquest, competition, and aggression than nurturance and communality.""

Note that this is a generalization that does not take into account psychopathy and ponerogenesis in society. It is interesting to note this mention of a "dopaminergic society" when we just learned that high dopamine is associated with Post Traumatic Stress Disorder, and knowing what we do about the effects of psychopaths on ordinary people.

If I'm driving points into the ground, please point me out; I'm frightened by the wall of text I just created. I think I should move on...

IN SUMMATION

So, to sum up, it seems that dopamine is very important for healthy functioning, although it's unclear how precisely this may be different for those with genetically-originating ADD/ADHD, particularly related to the DRD4 difference. In normal people dopamine fights depression, supports memory and emotional functions, and seems to have something to do with reward-punishment conditioning ("compulsive behavior"), yet at the same time abnormally low dopamine seems to associated with addictive behavior, indicating that dopamine has a role in allowing or supporting impulse-control. ADHD people are more susceptible to addiction statistically, and most often have lower dopamine levels than average. On the other hand, Post Traumatic Stress Disorder is associated with chronically high levels of dopamine and other neurotransmitters such as adrenaline. The high levels probably relate to dopamine's traumatic-memory-suppressive functions, and it may be involved in the fight-or-flight hypervigilance associated with PTSD. However, as far as N-back goes, I doubt that as a mental exercise it is going to lead to PTSD or PTSD-like symptoms any more than algebra problems or writing book reports will. That is, it is human abuse that would have to create a setting in which for trauma to occur, as the tasks themselves are neutral. I think we might want to look into what the effect of increased dopamine receptors actually is in practice. We should probably also keep in mind that the number of receptors is not a sliding-scale with a simple effect; these receptors are wired to neurons in specific configurations, so even if the mechanism is not apparent, the extra receptors may potentially be serving a beneficial purpose that heightens awareness through a particular mechanism related to the practice of the task (or not).

I've never had such an intense period of research before, this is something new to me! I hope I was able to bring together some valuable information for the discussion, even if I lost my original track and got carried away. I learned a lot!

I'm no expert on brain chemistry, and all of the above is just what I found via internet searches today. I tried to show a fairly balanced perspective, using the information available to me guided by my impressions about the subject. I noticed, Bud, that you admitted several times that you weren't entirely sure your ideas were correct, which I seemed to have forgotten (or worse, failed to recognize in the first place) before I started writing this post. In any case, this is what I have to present for now.

Thank you,
~HowToBe
 
Wonderful, HowToBe. I wish I could present such a well-done piece like that, but more often, my mind runs so far ahead of my fingers that even my English gets crappy sometimes, not to mention that I often take for granted that certain implications in my text might be clear to the reader.

I felt that Kesdjan is sharp enough to dissect the subject as well, so when he stepped in, I vibrated with a bit of excitement towards the prospect of learning something new and I may have come across a bit intense. As far as I can tell though, I really am open to wherever the discussion goes!

[quote author=HowToBe]
As an intensive concentration/awareness exercise, it is possible N-back may produce some stress during the activity, as will any intensive task.[/quote]

Yep, but the actual area that concerned me was the part about playing to exhaustion. That's more than 'some' stress. In fact it's enough to start growing new dopamine receptors according to the article I quoted and I'm not yet persuaded that it's such a good thing.


[quote author=HowToBe]
However, you seem to be implying that N-back will produce a stressed state outside of the exercise, and I don't see why this would be true. Physical exercise produces a bodily stress response, yet this does not mean a person will be more stressed in their life because they exercise![/quote]

Actually, what I was saying/suggesting was more like: playing n-back to exhaustion on a regular schedule can or will produce a stress state that might become addictive.

Regarding physical exercise, I can say from experience that I'm less stressed in daily life from doing exercise, but a person can get addicted to running! Or at least start showing a strong preference to regular running. In fact, that 'second wind' is when the sustained stress reaches the necessary level to initiate a neurochemical flooding. And when you stop running, for awhile you feel really crappy, just like any withdrawal, only not debilitating. At least, not for me.


[quote author=HowToBe]
You really seem to be taking a stance that more dopamine receptors is a "bad" thing.[/quote]

Well, do we really know that it's not? Look very closely at the material that you, yourself, provided and notice the difference between fact and interpretation and note the assumptions underlying the interpretations. Barkley did brilliant research, but he's not ADD. So, considering that he considered himself as a representative of 'normal', naturally the interpretations he assigned to his results became biased in favor of drugging.

To help you see it clearer: What if Barkley were ADD and considered himself normal? Would he have taken his results, shouted Eureka! and yelled: "I finally found the reason why almost all people are addicts and zombies!"?

How many times do the Sufi's and the C's have to point out the relationship between one's assumptions and how we see things before we start to 'get it'? Not that I represent the 'got it' so much as an ability to see some of the assumptions, at least. :)


[quote author=HowToBe]
How well do you understand the workings of dopamine and its receptors on the body and mind?[/quote]

You mean about the ones that concern me? I would say I know quite well from the effects. Other than that, the knowledge from my own experience, the experience of many, many others with the 'condition' as compared and contrasted with those who are 'normal', and my ability to draw inferences and make deductions from observations and the experience of others.


[quote author=HowToBe]
Firstly I must say that as a neurotransmitter, certainly dopamine is important, and having proper levels and a proper number of receptors must thus be important for the organism's well-being. Neurotransmitters are one way the body communicates with itself, and in general it seems rational that to increase the body's ability to communicate internally would improve organism functioning.[/quote]

Agreed. As far as I know, everything else about the neurotransmitter system - even for ADD folks, is normal and uncontested.

Here is where I (and maybe we as a group, or as society) can get lost:


[quote author=HowToBe]
I have done some quick research and found the following:

_http://www.wisegeek.com/what-are-dopamine-receptors.htm
"Dopamine receptors are one class or type of receptors that are found in the central nervous system as well as other key points near nerve endings in various organs. The receptors are instrumental in the proper function of the neurotransmitter dopamine, which has a significant effect on the function of the nervous system in regard to memory, general mood, and cognition. When the supply of dopamine to the receptors is inhibited in some manner, an individual may be begin to experience difficulty concentrating, become easily irritated, and possibly become severely depressed
[/quote]

Yep, and placing this data in a societal context, what I see is that this applies to 'normal' people most often when they aren't getting the 'hits' they've become accustomed to. There's a fairly well passed around story about how a certain teacher was able to remain completely under control and normal as long as all the children followed all the appropriate social rituals. But let an ADD child approach her desk and she begins to feel irritated and "just doesn't like the child". When asked about this child during an ADD assessment, she tried to explain her feelings but couldn't. The best she could manage was a comment about how she just doesn't like the way he sits in his seat.

This is not as uncommon as you might think. Fact is, ADD children cannot become unwittingly addicted to social rituals and conditioning and so they often forget how to "do it right". Stress-addicted people don't understand that. They seem to just experience the discomfort of withdrawal when everyone's not micro-synchronized.

For a child with ADD, "difficulty concentrating, become easily irritated, and possibly become severely depressed" may not be related as much to their dopamine levels as it is to the consequences of being in a 'normal' environment with it's 'normal' demands. Have you seen how energetic, productive, creative and intelligent some of them are at home where they can express themselves in their natural state? Go to youtube, type in ADHD and just check some of them out.


[quote author=HowToBe]
This means that someone who is currently dealing with unusual periods of irritation or depression may find that taking a dopamine agonist will alleviate those symptoms and restore a more balanced frame of mind.[/quote]

Of course. The key item of contention is how different people explain what the balance should be. A cocaine addict's brain is balanced with abnormal quantities of super chemicals so this statement would apply to the addict as well.


[quote author=HowToBe]
So if the trouble is with faulty receptors, maybe increasing the number of receptors could be a problem, and the above text might not apply in this special case. If the number of receptors is increasing despite their "faultiness", might this imply that they are doing something, possibly beneficial or harmful?[/quote]

That's what I'm thinking. This might, indeed, imply that they are doing something possibly beneficial or harmful. How can we come to know? Desiring to err on the side of caution, I would first like to find out the potential for harm.


[quote author=HowToBe]
In any case, it might help if you would provide more evidence that a higher dopamine receptor count might have a degenerative effect on total reasoning ability.[/quote]

You're tempting me right? :) Seriously though, do you think there might be any correlation between the current levels of dopamine molecules sexing up their corresponding receptors in the general population now, as well as recent past, and the general 'ability of these same people to reason'? Do we know if all those dopamine receptors would have sprouted up along with all our other growth from about age 5 or so, if we hadn't all been subjected to all the pathology and demands for mechanistic behavior? We don't know that do we? I'd like to, though.

Interestingly, in a chapter left out of the final printed version of the book: Thom's Complete Guide to ADHD, Thom Hartman writes:

Earlier in this book, I offered a complete and detailed psychological and neurological explanation for the driving mechanism behind ADHD. (All other theories I know of only address one or the other, and are thus incomplete.) In quick summary, I showed why and how those who think ADHD is a “top down” problem, such as a failure of cognition, inhibition, or even poor parenting, are totally and utterly wrong. Certainly there are differences among people in our ability to think and learn, our ability to inhibit behaviors ranging from eating to sex, and in the way we were raised. These variations play a small role in how ADHD is expressed, but are not at the core of ADHD behavior, as any person with ADHD can tell you.

The core mechanism, the driving force behind ADHD, is that need that Maslow overlooked when he assembled his hierarchy of human needs: the need to know one is alive. As mentioned, because of genetically determined differences in the set-point of the thalamus, which controls how “in touch” we each are with the sensory world, some of us are born knowing we are alive and never questioning it because lights are bright, sounds are loud, and touch is vivid. Others of us, however, feel the constant need to reach out for stimulus that will verify our aliveness, proving to us that we are really here and now and fully alive.

I can vouch for the intensity of the stimulus.


[quote author=HowToBe]
_http://borntoexplore.org/neurochem.htm
"Reduced dopamine/norepinephrine caused by boring surroundings and lack of exercise may manifest as ADD, impulsivity, lack of concentration, restlessness, and depression or loss of pleasure.[/quote]

Yep, but notice how facts can be used to avoid stating the implication of a need for more dopamine. This statement also sounds like a person in a beneficial (and hopefully temporary) withdrawal process.

[quote author=HowToBe]
Dopamine is the "feel good" chemical which illegal drugs mimic (such as cocaine, heroin, marijuana) as well as cigarettes, coffee and alcohol. Ritalin and other ADD drugs are thought to increase dopamine activity."[/quote]

Yep. It's in The Wave also. That chapter on Addiction cannot be beat, y'hear me? :D

[quote author=HowToBe]
_http://adhd-treatment-options.blogspot.com/2008/09/adhd-gene4-dopamine-beta-hydroxylase.html
"Of somewhat interest is the fact individuals with ADHD are statistically more susceptible to contracting Parkinson's later in life than the rest of the general population."[/quote]

I'd like to review those statistics. At the moment, I'm thinking that after a lifetime of stress and chemical abuse, anyone might be "more susceptible to contracting Parkinson's". Perhaps those ADHD subjects happened to be among those most heavily medicated (out of the total number in the study) for the longest period of time? They would have burned out faster, I reckon.


[quote author=HowToBe]
_https://secure.wikimedia.org/wikipedia/en/wiki/Parkinson%27s_disease
"Parkinson's disease (also known as Parkinson's, Parkinson disease, or PD) is a degenerative disorder of the central nervous system that impairs motor skills, cognitive processes, and other functions.
[...]
Symptoms result from insufficient formation and action of dopamine produced in the dopaminergic neurons of the midbrain (specifically the substantia nigra).
[...]
[/quote]

What is known to be the cause of Parkinson's? We don't know that do we? But we can say:

The primary symptoms of Parkinson's disease result from greatly reduced activity of dopamine-secreting cells due to cell death in the pars compacta region of the substantia nigra."

Why did the cells die? Brain overheating? Excess production over the course of a lifetime? Do any of the dopamine-secreting cells have a biologically-set lifetime? If so, should be taking more cautious thought about anything and everything that causes dopamine production to increase?


[quote author=HowToBe]
_http://ajp.psychiatryonline.org/cgi/content/full/158/12/2015
"A consistent finding in drug-addicted subjects is a lower level of dopamine D2 receptors. In cocaine abusers, low levels of D2 receptors are associated with a lower level of metabolism in the orbitofrontal cortex. Because the orbitofrontal cortex is associated with compulsive behaviors, its disruption may contribute to compulsive drug intake in addicted subjects."

This is especially interesting, as this could indicate that increased numbers of dopamine receptors may decrease one's risk of addictive behaviors.[/quote]

Surely. Under the influence of a particular level of the stuff, why would I want to do anything, let alone anything 'risky'? :)


[quote author=HowToBe]
If I'm driving points into the ground, please point me out; I'm frightened by the wall of text I just created. I think I should move on...[/quote]

That's funny. You've got a sense of humor! :)


I noticed, Bud, that you admitted several times that you weren't entirely sure your ideas were correct, which I seemed to have forgotten (or worse, failed to recognize in the first place) before I started writing this post.

Hey, I appreciate your contribution to the subject and your understanding.

I can't always tell when, from my POV, me being pensive or doubtful about something gets interpreted as 'active opposition' or whatnot. I guess my occasional intensity just mirrors my interest in the subject!
 
There is plenty here for me to think about, but there are a few things I could say.

Bud, I think the only way to know whether the game is as "exhausting" as you think, is to play it yourself and decide. Personally I have never experienced "hyper" focus or anything like that. If I have it was less focus and more a self-stress thing which produced the opposite effect, to narrow my mind and overwhelm the circuits doing the work. I don't consider this to be focus, so I avoid it. In fact, I have never known my brain to suddenly go into some different mode in order to do something, or if it has, any benefits I later realized were primarily imagined. So it seems to me that "hyperfocus" or something like that would be someone's way of forcing a change in brain chemistry because they are not satisfied with their current progress and wishfully think because of the sensation of an imbalanced brain that their abilities are increasing. Rather, I have found that the greatest increase in focus or ability comes from dissolving one's misconceptions and assumptions of that moment so they can proceed with an open mind, unimpeded by programs or stereotypes that have outlived their purpose. Beyond this, the brain is trained to the ways of thinking it is used most for.

But this must be far simplified as to that way the brain actually works, and it is likely there are caveats here and there; we would know if we had a clear view of the data. But as Bud points out, much is simply interpretation, and interpretation depends highly on the individual.
 
I understand what you're saying, monotonic, and I appreciate the leeway with regard to my expressions on your thread.

Factually, it's not n-game or any other game that I care about. It's mostly just people. 'Games' and 'subjects' are useful ways to address people, though, due to their own concerns and because of our common goals in the Work. In and of themselves, games are neither good nor bad, of course.
 
[quote author=monotonic]
My impression is that this game could be very helpful for the Work, if someone could understand it in that context and find out how to use it towards that end.
[/quote]
The N-back game seems to impart training in focus and concentration - the type of focus that is narrow in scope and filters out distractions. It is also designed to improve what is called working memory since one has to remember multiple things at the same time.
Regarding "working memory" in the context of the Work, I do not think games like N-back are helpful. In the context of the Work, memory is based on understanding like what Bud mentioned. Mouravieff writes
[quote author=Gnosis Book 1 pg 29]
Memory is a direct function of the being of an individual. The higher the level of being, the better the memory and the greater its capacity to contain.
[/quote]
Playing games do not aid in understanding directly. It can be said that it may help train brain pathways which lets one retain information. But is a game like N-back really helpful for increasing what is true cognitive flexibility (as per Steven Mithen's "Prehistory Of the Mind") - that which helps in combining diverse information from diverse areas of human experience to further understanding? Reading and thinking with a relaxed focus (which does not demand that some concrete results emerge immediately from what is being done) is what I have found helpful in relation to cognitive flexibility. It seems less mechanical and more direct - but that could be a personal preference.

Coming back to the topic of attention, having narrow focus task-based attention is the usual norm in today's society and this usually generates stress. Even if Nback is "just a game", the model is that of a test where one's performance is being measured in success/failure terms and any such situation automatically results in a stress response for most people. But the level of stress will probably go down with practice and as one gets good at it. Then, whether this activity becomes addictive (as many games are) is something that may be worth observing.
I do not know anything about the possible therapeutic effects of such games on ADD sufferers. However, I would like to point out an alternative approach to attention as outlined by Dr Lester Fehmi which is posted on this thread Brain Waves and Attention . The approach is different from the neurochemical based approach to understanding attention and intelligence.

fwiw
 
Bud said:
Wonderful, HowToBe. I wish I could present such a well-done piece like that, but more often, my mind runs so far ahead of my fingers that even my English gets crappy sometimes, not to mention that I often take for granted that certain implications in my text might be clear to the reader.
Sometimes I get lucky. I also have the habit of rereading every sentence after writing it. When I complete a paragraph (a complex idea), I reread the paragraph. Finally, once I have finished a post, I skim-read the whole post. I'm checking for writing errors, false logic, and trying to improve structure and clarity. This may be because my first experience with posting things on the internet was on a role-playing forum, but I think I may have tended toward this type of thoroughness before then.

You made some good points as well. It does appear that dopamine itself is potentially addictive, and I understand the cautionary approach in light of that. The perspective of dopamine withdrawal seems very revealing as well. Finally, you are right, I need to continue reading The Wave.

Overall, my interpretation so far is thus:
N-back, as a game that trains the mechanical aspects of the mind, is primarily related to the lower intellectual center. It is useful to the Work to the extent that it brings the lower intellectual center into balance with the other lower centers. This will vary depending on the individual. For some it may be helpful, for others it may be harmful, and even this depends on the circumstance. From a practical perspective, I think that N-back could be useful to the extent that it can help people to carry out the narrow-focus tasks required by society (schoolwork, for instance) more efficiently when they are required, thus allowing more time, space, and energy for personal work, or Work for those capable. As far as n-back or other repetitive tasks becoming addictive beyond a certain point, that will depend on the individual, and perhaps it is up to the individual to be self-aware in this matter. A tendency toward addiction will generally manifest eventually with or without N-back, I think.

However, since I've serendipitously happened across another piece of information on the Eiriu Eolas website, I'm going to follow the trail it leads me on.

http://eiriu-eolas.org/2011/01/21/meditation-boosts-part-of-brain-where-add-addictions-reside/ said:
Compared to a control group that underwent only relaxation training, brain scans of the students who meditated for a total of at least 11 hours during the month had slightly increased connections in the white matter that connects the anterior cingulate cortex to the rest of the brain; by some measures, these connections were also more robust. The ACC processes decisions, conflicts, and rewards, and deficits in that area have been linked to ADD, depression, dementia, addictions, and schizophrenia.

While the study was small in scale, the authors hope that the training might eventually be used for therapy or intervention for these conditions, as well as a general way of making people less impatient, greedy, and anxious.
(bold in original)

So, I'd like to know how this connects to N-back, if at all. So, first, let's see what N-back does to this 'anterior cingulate cortex'. This was all I could find:

_http://www.scribd.com/doc/36860150/Working-Memory-Capacity-and-Its-Relation-to-General-Intelligence said:
[...]significant correlations were observed between RAPM, n-back, and activity in DLPFC and ACC.

RAPM in this case stands for "Raven's Advanced Progressive Matrices", with a description here: https://secure.wikimedia.org/wikipedia/en/wiki/Raven%27s_Progressive_Matrices .
So, we have correlations in activity, but not necessarily growth, although activity generally precedes growth as far as I'm aware. Also, there is this DLPFC or "Dorsolateral Prefrontal Cortex", which I'll check out in a moment. Concerning the ACC:

http://www.sott.net/articles/show/178072-Brain-Differences-Found-Between-Believers-In-God-And-Non-believers said:
Compared to non-believers, the religious participants showed significantly less activity in the anterior cingulate cortex (ACC), a portion of the brain that helps modify behavior by signaling when attention and control are needed, usually as a result of some anxiety-producing event like making a mistake. The stronger their religious zeal and the more they believed in God, the less their ACC fired in response to their own errors, and the fewer errors they made.

"You could think of this part of the brain like a cortical alarm bell that rings when an individual has just made a mistake or experiences uncertainty," says lead author Inzlicht, who teaches and conducts research at the University of Toronto Scarborough. "We found that religious people or even people who simply believe in the existence of God show significantly less brain activity in relation to their own errors. They're much less anxious and feel less stressed when they have made an error."

This suggests that increased ACC activity may be connected to or cause stress. However, Based on the article about meditation, the ACC is important in relation to stress and overall mental health, so increased connections in the ACC may be beneficial, as this may indicate that the brain is getting better at detecting errors and contradictions. I seem to recall a SOTT article linking abnormally low ACC activity to psychopathy, but I'm not finding it. So, back to this "Dorsolateral Prefrontal Cortex":

_https://secure.wikimedia.org/wikipedia/en/wiki/Dorsolateral_prefrontal_cortex said:
"DL-PFC serves as the highest cortical area responsible for motor planning, organization, and regulation. It plays an important role in the integration of sensory and mnemonic information and the regulation of intellectual function and action. It is also involved in working memory. However, DL-PFC is not exclusively responsible for the executive functions. All complex mental activity requires the additional cortical and subcortical circuits with which the DL-PFC is connected.

Damage to the DL-PFC can result in the dysexecutive syndrome, which leads to problems with affect, social judgement, executive memory, abstract thinking and intentionality.
So that's interesting, although it doesn't seem to tell me anything. So let's look into these "executive functions" we keep hearing about:

The executive system is thought to be heavily involved in handling novel situations outside the domain of some of our 'automatic' psychological processes that could be explained by the reproduction of learned schemas or set behaviors. Psychologists Don Norman and Tim Shallice have outlined five types of situations in which routine activation of behavior would not be sufficient for optimal performance:[2]

1. Those that involve planning or decision making
2. Those that involve error correction or troubleshooting
3. Situations where responses are not well-rehearsed or contain novel sequences of actions
4. Dangerous or technically difficult situations
5. Situations that require the overcoming of a strong habitual response or resisting temptation.

The executive functions are often invoked when it is necessary to override responses that might otherwise be automatically elicited by stimuli in the external environment. For example, on being presented with a potentially rewarding stimulus, such as a tasty piece of chocolate cake, a person might have the automatic response to take a bite. However, where such behavior conflicts with internal plans (such as having decided not to eat chocolate cake while on a diet), the executive functions might be engaged to inhibit that response.

Although suppression of these "prepotent responses" is ordinarily considered adaptive, problems for the development of the individual and the culture arise when feelings of right and wrong are overridden by cultural expectations or when creative impulses are overridden by executive inhibitions.[3]

The neural mechanisms by which the executive functions are implemented is a topic of ongoing debate in the field of cognitive neuroscience. Traditionally, there has been a strong focus on the frontal lobes, but more recent brain research indicates that executive functions are far more distributed across the cortex.
(bold mine)
Executive functions sound like something a person might want to have! In the context of the Work, this sounds like the first directly relevant piece of information turned up by this research. I'll hazard a tentative guess that self-remembering may train executive functions, or present the opportunity to do so by resisting temptation and habit. However, perhaps there is danger of going overboard to the point of self-suppression, as Bud suggested earlier. Lastly, how does the Dorsolateral Prefrontal Cortex relate to meditation? Here's a study:

_http://www.ncbi.nlm.nih.gov/pubmed/18955268 said:
For the overall group (n = 13), and using an overall brain analysis, there were no statistically significant regional activations of interest using conservative thresholds. A region of interest analysis of the entire group time courses of DLPFC and ACC were statistically more active throughout meditation in comparison to the control task. Moreover, dividing the cohort into short (n = 8) and long-term (n = 5) practitioners (>10 years) revealed that the time courses of long-term practitioners had significantly more consistent and sustained activation in the DLPFC and the ACC during meditation versus control in comparison to short-term practitioners.
(my bold)

Even better, this study deals with mindfulness meditation specifically:

_http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569815/ said:
The present study revealed that meditators show increased gray matter concentration in regions that are relevant for meditation. Gray matter concentration was significantly greater for meditators in the right hippocampus and the right anterior insula and showed a trend towards significance in the left inferior temporal gyrus.
[...]
Data did not confirm the expected differences at the DLPFC, ACC and left postcentral gyrus. Also, no effect of meditation training has been found on the cortical thickness in these regions (Lazar et al., 2005). Possibly, the activation of these regions during meditation training does not lead to alterations in cortical structure. It is conceivable that some brain regions are more amenable to structural modifications than others.

Very interesting. For the moment, I'm not going to look into any more brain regions, but it is interesting that the DLPFC and ACC showed no growth in this study, as compared to studies on other meditation forms.

Anyway, that is all for now. It doesn't appear that my interpretation of the data at the beginning of this post is altered by the new info.

~HowToBe
 
Warning: this post is way too long and shouldn't be read by anyone, under any circumstances. Unless the subject interests you. :)

HowToBe said:
http://eiriu-eolas.org/2011/01/21/meditation-boosts-part-of-brain-where-add-addictions-reside/ said:
Compared to a control group that underwent only relaxation training, brain scans of the students who meditated for a total of at least 11 hours during the month had slightly increased connections in the white matter that connects the anterior cingulate cortex to the rest of the brain; by some measures, these connections were also more robust. The ACC processes decisions, conflicts, and rewards, and deficits in that area have been linked to ADD, depression, dementia, addictions, and schizophrenia.

While the study was small in scale, the authors hope that the training might eventually be used for therapy or intervention for these conditions...

Well, meditation does help. Specifically, existing psychology publications and ADHD practitioners seem to give Mindfulness and TM good reviews. Personally, I find EE breathing methods relaxing and helpful for dealing with situations intended for calm, waiting type behaviors, whether waiting at redlights, in Doctor's office waiting rooms or whatever.

As far as I can tell though, the evidence for NEED of this kind of training is literally circumstantial, since that is simply how society is arranged and how so many circumstances are set up.


HowToBe said:
Executive functions sound like something a person might want to have! In the context of the Work, this sounds like the first directly relevant piece of information turned up by this research.

OK, so let's have a closer look shall we?

*************************************************************
*************************************************************

Executive Functions of the Frontal Lobes: A New Perspective on an Old Story

On September 13, 1848, an apparently responsible, capable, and virile 25-year-old foreman of a railroad construction crew, named Phineas Gage, accidentally dropped a 131/4-pound iron tamping rod on a dynamite charge. The resulting explosion drove the rod through the left side of his face and out the top of the frontal portion of his cranium.
...
Seventy-four days after the accident, Phineas was able to return to his home 30 miles away. But there were discernible differences in Phineas’s behavior, not related to his health, general intelligence, or memory.

Physician J. M. Harlow (1868) was Phineas’s attending physician. Harlow wrote about the changes in behavior that happened after the patient's accident. Clearly, Harlow was associating Phineas’s most important change to the loss of his once shrewd business acumen and his former ability in “executing all of his plans of operation.”

Harlow’s description may have been the first in the written psychological literature for the frontal lobe metaphor: that the frontal lobes serve as a kind of executive that makes decisions, forms goals, devises strategies for attaining these goals, plans, organizes, and changes and devises new strategies when initial plans fail.

Subsequently, this executive functions model has been developed by a scientific discipline known as neuropsychology. This field provides explanations for brain and behavior relationships based on studies of brain-damaged patients, clinical populations with suspected brain dysfunction, and healthy people.

Tests and measurements on the latter group (healthy people) help to define what normal or average functioning is so that behavior that deviates from standard functioning can be better defined. Neuropsychology is also broadly concerned with how the brain and its parts function and in identifying the symptoms of dysfunction.

One of the most prominent neuropsychologists of modern times was Russian Alexander Luria (1966), who wrote extensively about these executive functions of the frontal lobes.

Luria noted that patients with frontal lobe damage frequently had their speech, motor abilities, and sensations intact, yet their complex psychological activities were tremendously impaired. He observed that they were often unable to carry out complex, purposive, and goal-directed actions. Furthermore, he found that they could not accurately evaluate the success or failure of their behaviors, especially in terms of using the information to change their future behavior. Luria found that these patients were unconcerned with their failures, and were hesitant, indecisive, and indifferent to the loss of their critical awareness of their own behaviors.

Lezak (1982), a contemporary American neuropsychologist, wrote that the executive functions of the frontal lobes were:

...the heart of all socially useful, personally enhancing, constructive, and creative abilities. Impairment or loss of these functions compromises a person’s capacity to maintain an independent, constructively self-serving, and socially productive life no matter how well he can see and hear, walk and talk, and perform tests. (p. 281)

Welsh and Pennington (1988) defined executive functions in a neuropsychological perspective as the ability to maintain an appropriate problem-solving set for the attainment of a future goal. Pennington and Ozonoff (1996) view the domain of executive functions as distinct from cognitive domains such as sensation, perception, language, working memory, and long-term memory. Also, they see it as overlapping with such domains as attention, reasoning, and problem-solving “but not perfectly.” (p. 54). They also add interference control, inhibition, and integration across space and time as other aspects of executive function.

Their central view of executive function is a: context-specific action selection, especially in the face of strongly competing, but context-inappropriate, responses. Another central idea is maximal constraint satisfaction in action selection, which requires the integration of constraints from a variety of other domains, such as perception, memory, affect, and motivation. Hence, much complex behavior requires executive function, especially much human social behavior. (p. 54)

The rise of Homo sapiens: the evolution of modern thinking, By Frederick Lawrence Coolidge, Thomas Wynn, pg. 4 "Introduction", 2009, Wiley-Blackwell.
_http://books.google.com/books?id=Kds57ItEf38C&pg=PA4&lpg=PA4&dq=%22Welsh+and+Pennington+%281988%29+defined+executive+functions+in+a+neuropsychological+perspective%22&source=bl&ots=-9xRxsXbYd&sig=oqMUufpEyb3lHm2pglfBR5WOcYo&hl=en&ei=899ZTc-WGc3HtwfFr9TGCw&sa=X&oi=book_result&ct=result&resnum=1&ved=0CBMQ6AEwAA#v=onepage&q=%22Welsh%20and%20Pennington%20%281988%29%20defined%20executive%20functions%20in%20a%20neuropsychological%20perspective%22&f=false

A 6 page pdf of the Introduction:
_http://media.wiley.com/product_data/excerpt/32/14051525/1405152532.pdf


************************************************************************************

So, Executive functions are said to be basically the management system of the brain.

Thomas E. Brown, PhD, clinical psychologist and leading researcher on executive functions, identifies six clusters of cognitive functions that constitute a way of conceptualizing executive functions.

Cluster 1) Activation: Organizing, Prioritizing and Getting Started on Tasks
A student with deficits in this area of executive functioning has difficulty getting school materials organized, distinguishing between relevant and nonrelevant information, anticipating and planning for future events, estimating the time needed to complete tasks, and struggles to simply get started on a task.

Cluster 2) Focus: Focusing, Maintaining and Shifting Attention
A student who is easily distracted misses important information provided in class. He is distracted not only by things around him in the classroom but also by his own thoughts. He has difficulty shifting attention when necessary and can get stuck on a thought, perseverating only on that topic.

Cluster 3) Effort: Regulating Alertness, Sustaining Effort, Processing Speed
A student who has a hard time regulating alertness may become drowsy when he has to sit still and be quiet in order to listen to a lecture or read material that isn’t very interesting and stimulating. It is not that he is overtired, rather he simply can’t sustain his alertness unless he is actively engaged. In addition, the speed at which a student takes in and understands information can affect school performance. Some students with ADHD process information very slowly, while others may have trouble slowing down enough to process information accurately.

Cluster 4) Emotion: Managing Frustrations and Regulating Emotions
A student with impairments in this area of executive functioning may have a very low tolerance for frustration and be extremely sensitive to criticism. Difficult emotions can quickly become overwhelming and emotional reactions may be very intense.

Cluster 5) Memory: Using Working Memory and Accessing Recall
Working memory is a “temporary storage system” in the brain that holds several facts or thoughts in mind while solving a problem or performing a task. Working memory helps an individual hold information long enough to use it in the short term, focus on a task and remember what to do next. If a student has impairments in working memory, he may have trouble remembering and following teacher directions, memorizing and recalling math facts or spelling words, computing problems in his head or retrieving information from memory when he needs it.

Cluster 6) Action: Monitoring and Self-Regulating Action
Individuals with this impairment often seem to have deficits in the ability to regulate their behavior, which can significantly impede social relationships. If a student has difficulty inhibiting behavior he may react impulsively without thought to the context of the situation, or he may overfocus on the reactions of others by becoming too inhibited and withdrawn in interactions.
_http://add.about.com/od/adhdthebasics/a/Execu-Functions.htm

-------------------

Barkley's model:

Russell A. Barkley, Ph.D., is an internationally recognized authority on attention deficit hyperactivity disorder (ADHD) in children and adults. Dr. Barkley has specialized in ADHD for more than 30 years and is currently a Clinical Professor of Psychiatry at the Medical University of South Carolina.

In 1997 when Barkley first presented a variation on Strang and Rourke's 1983 Executive Functions model to explain ADHD, Barkely chose to incorporate into his model the existing body of literature of brain function, and to emphasize the similarity between symptoms of pseudopsychopathy (right frontal lobe damage) and ADHD. The right-frontal-lobe brain damaged individual has been shown to experience increases in motor activity, talkativeness, and a lack of tact and restraint,(19) symptoms commonly associated with ADHD. Animals with frontal lobe damage cannot adapt to new situations or environments, while humans with such lesions similarly experience extreme difficulties in situations requiring problem solving and unique solutions(19).

Because he assumes ADHD to be synonymous with this type of brain damage," Barkley(3) concluded, rather incorrectly, that persons with ADHD are also less capable of creative thought, and stated this hypothesis concerning ADHD and creativity explicitly in several of his writings.

In the September, 1998 edition of Scientific American magazine, Barkley spells out his version of the model:

Russell Barkley states that the Executive Functions can be grouped as a set of 4 mental activities:

1) working memory: Holding information in mind while working on a task, even after the original stimulus is gone. said to be crucial to timeliness and goal-directed behavior. Also provides the means for hindsight, forethought, preparation and the ability to imitate the novel behavior of others.

2) internalizing self-directed speech. Said to allow one to reflect to oneself, to follow rules and instructions, to use self-questioning as a form of problem solving and to construct "meta-rules", the basis for understanding rules about rules - all quickly without tipping one's hand to others. The idea is to make this self-talk private, preventing others from knowing one's thoughts.

3) Controlling emotions, motivation and state of arousal. Said to help individuals achieve goals by delaying or altering potentially distracting emotional reactions to a particular event and to generate private emotions and motivations. Those who rein in their immediate passions can behave in more socially accepted ways.

4) Reconstitution. Said to encompass two separate processes: breaking down observed behaviors and combining the parts into new actions not previously learned from experience. Said to give humans a great degree of fluency, flexibility and creativity and allows them to propel themselves toward a goal without having to learn all the steps by rote. Also said to permit children, as they mature, to direct their behavior across increasingly longer intervals by combining behaviors into ever longer chains to attain a goal.

Barkley states the essence of his ADHD model thusly:
"In the early years [In all children], the executive functions are performed externally: children might talk out loud to themselves while remembering a task or puzzling out a problem. As children mature, they internalize, or make private, such executive functions, which prevents others from knowing their thoughts. Children with ADHD, in contrast, seem to lack the restraint to inhibit the public performance of these executive functions."

...and he states it again:
All 4 Executive functions become internalized during typical neural development in childhood. As normal children grow and develop, they develop the capacity to behave covertly, to mask some of their behaviors or feelings from others. Either through faulty genetics or embryonic development, ADHD children have not attained these covert abilities and therefore display too much public behavior and speech.

Barkley then covers Ritalin and how it improves the Executive functions and mentions the justified results:
"...they tend to be liked better by other children and to experience less punishment for their actions, which improves their self-image."

------------------------
------------------------

Thom Hartmann states the he and his son is diagnosed ADHD. He's a prolific author on ADHD and the inventor of the Hunter vs. farmer theory of the condition.

Hartmann (with co-author Vaudree Lavallee) has this to say about Barkley's doings:

If brain damage research had been used to build the Hunter/Farmer hypothesis, "ADD: A Different Perception" may have explored the difficulties associated with being a right-frontal-lobe-damaged individual in a world taken over by people with left-frontal-lobe-damage. Described in non-disorder (difference) terms, left-frontal-lobe-damaged "Farmers" could be seen as objective (rather than indifferent), exerting emotional self-control (rather than showing little overt emotion), able to show enough self-regulation to remain silent (rather than showing little or no verbal output), and speaking only when spoken to (rather than failure to initiate conversations).

However, this silly analogy was never used in "ADD: A Different Perception," or any subsequent Thom Hartmann book or article for that matter, because Hunters are not right-frontal-lobe brain damaged persons, and Farmers are not left-frontal-lobe brain damaged persons: each are, instead, two end-points on a continuum of human variability.

To understand the role of brain pathology research in validating the Executive Functions model, we need to first determine what the Executive Functions model would look like without reference to brain damage. The Executive Functions model would still compare the more liberal and flamboyant ADHDers unfavorably to the more conservative and restrained "statistical norm." Americas "brick" factory-like schoolhouses would still be seen as the epitome of human civilization and accomplishment. And, like Phillip Rushton,(11) the Executive Functions model would still see a negative correlation between IQ and promiscuity.

In summary, we would still have an ethnocentric (almost Aryan) commentary of genetic endowment differences.

Without these highly questionable (and, in the opinion of these authors, outright flawed) ideological underpinnings, however, what remains of the Executive Functions model is simply a theory of individual variation. The Executive Functions model tends to focus on post base-line variation in human response to environmental stimulation while ignoring important differences in how such stimulation may initially be experienced by the individual. We agree that after controlling for base-line differences between Hunters and Farmers, there may be important executive function differences among Hunters and among Farmers. Additionally, these "executive function" differences may turn out to be one among the many variables which help determine whether ADHD will produce an entrepreneurial success or a chronic criminal.

As the Hunter/Farmer hypothesis predicts, there are base-line differences in the ways individual Hunters and Farmers each experience and cope with depression, boredom, frustration and joy. However, these base-line differences do not fully explain why one Hunter (or Farmer for that matter) may or may not experience depression at a dysfunctional level.

Instead, the Hunter/Farmer hypothesis suggests that it's the driving need or hunger for aliveness which animates most ADHD/ADD behaviors, and executive function is only a small (but significant) variable that determines how this need or hunger is satisfied (through socially adaptive means, such as a high-stimulation job in an emergency room, or socially maladaptive means like becoming a barroom brawler).

Seen in this light, Barkley's so called executive system may be nothing more than a fight or flight response mechanism, acting like a rubber band that exerts its influence at both ends of the ADHD continuum. Evidence which indicates that having a "happy temperament" as an infant is associated with improved prognosis for Hunters while some environmental factors, such as having experienced abuse, are associated with negative life chances(13) lends support to the prospect that the Executive Functions model is a theory of within-Hunter variation rather than of Hunter/Farmer differences.

To recapitulate, if one were to divide the population into groups based on individual differences in tolerance of (or desire for) novelty, the individuals in each group would still vary in both their tolerance of and their exposure to adversity or stress.

Theoretically, those in each group whose threshold for stress has been exceeded may exhibit many of the cognitive difficulties associated with the so-called executive functions.

From: ADHD - disorder or difference?, Thom Hartmann & Vaudree Lavallee

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Pro-ADD Studies?

In the newsletter: Every Day With ADHD, Kerry Cooney & Steve Oldham quote Thom Hartmann:

No studies I know of have looked for ADHD children who are functioning well in school, or ADHD adults who are functioning well in life (although we all know of examples of the latter, from actors to entrepreneurs to inventors to artists). Because publications of the psychology and psychiatry industries concern themselves only with pathology (there is no listing for "normal" in the Diagnostic and Statistical Manual of The American Psychiatric Association, for example), it should not surprise us that they find it. Nor should it surprise us that they wouldn‘t bother to look for or at those who are not "failing" in society, and thus not potential customers.

Several studies have provided us with hints that ADHD may be useful somehow, somewhere, sometime. One of the most interesting was a Washington University study in which ADHD persons were tested against "normal" controls for their ability to handle emergencies: what the study’s authors called "urgent tasks."

The abstract reads:

Attention-deficit hyperactivity disorder (ADHD) has been proposed to represent adaptive responding to highly urgent situations in primitive hunting. In the present study, 31 adults with self-reported ADHD were compared with 33 normal adults on a newly developed, 10-item measure of urgent task involvement. The internal consistency of the scale was suitable, and the group with ADHD scored significantly higher than the control group, as predicted.

While this was the first study to demonstrate that people with ADHD had some advantage in some circumstances over others, many previous studies offer tantalizing glimpses which the researchers chose not to pursue.

For example, one study found that while "normal" children’s ability to read or perform tasks requiring vigilance deteriorated when they were "distracted" by high levels of external stimulation, ADHD children’s scores actually improved.

Another study found that boys with ADHD calmed down when they were in highly stimulating environments, whereas "normal" children would crash-and-burn under such circumstances.

An article in The Journal of Creative Behavior by University of Georgia’s Bonnie Cramond asks the question in its abstract: "There are so many similarities in the behavioral descriptions of creativity and ADHD that one is left to wonder, could these be overlapping phenomena?" The article goes on to suggest that a thorough search of the literature in both fields would imply the answer is yes.

It concludes:

Perhaps individuals who have trouble with verbal learning but have a very imaginative, visual manner of thinking will be considered at the forefront of innovation in our society rather than as problem learners. Taken together, the results of these studies and others like them are indicative of a childhood syndrome characterized by hyperactivity and high intelligence, in which personality variables, modes of cognitive representation and creativity are intimately bound.

Also printed here: Thom Hartman, "Whose order is being disordered by ADHD?
Originally published in Tikkun Magazine _http://www.tikkun.org

This newsletter has a bunch of helpful tips and advice for raising an 'ADHD' child:
_http://everydaywithadhd.com.au/user-assets/ENews/Newsletter_005.pdf

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According to the fourth edition of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), a child has ADHD if, for a period of six months, he or she exhibits at least six symptoms from a list of 14. Among them: "often has difficulty organizing tasks and activities," "is often easily distracted by extraneous stimuli," "often fidgets with hands or feet or squirms in seat," and "often blurts out answers before questions have been completed." (In the full listing, please note the precise language used in the DSM-IV definition, such as "often," "excessively" and "extraneous").

Parents are frequently surprised to learn that the clinical observation of these symptoms, over the span of a 10-minute doctor's consultation, is the sole basis of an ADHD diagnosis. After all, aren't all kids "easily distracted" some of the time? Isn't a certain amount of hyperactivity a natural part of childhood?
_http://reason.com/archives/2000/05/01/dangerous-distraction

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Similarly, those who don’t care to look for ADHD among the ranks of the successful would overlook Harvard psychiatrists and professors of psychiatry, Drs. John Ratey and Edward Hallowell, authors of the best-selling book Driven to Distraction, in which they state explicitly that they each "have ADD."

It was never the strength of the science, however, that carried the day for the biomedical view of ADHD. All of a sudden there was a legitimate medical diagnosis that explained away uncooperative children, eased parental guilt, relieved teachers' anxiety, and lined the pockets of pharmaceutical companies and HMOs. Is it any wonder that this diagnosis caught on? As the opening sentence of an early book on the subject, Edward Hallowell and John Ratey's Driven to Distraction, prophetically (though unironically) observed, "Once you catch on to what this syndrome is all about, you'll see it everywhere."
_http://reason.com/archives/2000/05/01/dangerous-distraction

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Check out this Consensus Development Conference on ADD/ADHD 1998:

Even a panel of Doctors can’t seem to describe ADD/ADHD.

Note the part of the video where this panel of 'experts' are unable to define the symptoms or diagnosis of ADD or ADHD. I didn't watch the whole thing. I was kind of embarrassed for them, I guess.
http://www.youtube.com/watch?v=KcgYQfvjMD8

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Here's Hartmann's summary:

In summary, we find the work of those who attempt to position ADD/ADHD entirely as a pathology, "a failure of evolution," or a character trait of "no value whatsoever," to be more rooted in thinly-veiled pseudo-morality and eugenics than in science. Vast bodies of literature -- as well as common sense and the positive personal experiences of millions with ADHD -- are conveniently ignored, overlooked, or dismissed. In Barkley's words we find contempt and a reductionist, mechanistic world-view that allows only for pathology and non-pathology.

By obsessively focusing on negatives and refusing to acknowledge any evidence of value in ADHD, anywhere, anytime, under any circumstances, the increasingly small circle of "pure pathology" advocates are bringing only pain, power-based relationships (between parents told to "take charge" of their ADHD children, as well as between professionals and their clients), and the most massive labeling, segregation, and ostracizing seen in our public schools since the early days of "separate but equal" education among the races.

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So, it seems we have at least two gene clusters: one of which includes the DRD4 variation and the R7 DAT alle. The other without the variation. And seemingly correlated with two behavior clusters that researchers seemed to be mainly concerned with: The 'AD/HD' behavior cluster and the 'Normal' behavior cluster.

Of the gene in question: AD/HD researchers call it the AD/HD gene, naturally. Israeli scientists call it the "novelty seeking" gene. Others have called it the "alcoholism" gene. It's also been called the "Celtic" gene. Geez, you'd think these people would pool their research to find out they are all talking about the same thing.

Note: It seems from the better research out there, the ancient Celts were mentioned because they seem to have had the same or similar behavior clusters that are currently associated with the 'ADHD' gene cluster.

Of the Celtics, Laura writes:

Laura said:
However, studying what is available closely, one gets the impression of a dynamic, somewhat undisciplined people. The Celts were proud, imaginative, artistic, lovers of freedom and adventure, eloquence, poetry, and arts. You can always discern the Celtic influence by the great artistic talents of these peoples.

One of the Celtic languages was said to be Gaelic and we even use the Irish-Gaelic word: Eíriú Eolas for the Breathing/Meditation program!

I wonder what Barkley would say about the creativity of the Celts? Oh, wait. They were wiped out. Probably by the same venomous mindset Barkley displays with his direction that "they must be authoritatively controlled!"

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So, is N-Game addictive or potentially addictive? I think that when one begins playing the game for some useful, educational purpose, it would be OK. But the player would have to evaluate any benefits him or herself.

For someone with 'ADHD', it is likely that while playing, when a line is crossed where the player starts out with "want to" but continuing the game becomes "must", then the normal stress of concentration becomes an unhealthy kind of stress which may begin to build to this:

monotonic said:
N-back is not nearly so much an indulgence as other "brain games". It is exhausting. No one would play it unless they had some other reason. I find my automatic reaction has always been to try and avoid or put off playing it in any way possible, especially for as long as 25 minutes.

...eventually triggering a neurochemical flooding when the individual's stress tolerance is reached. For me and most other ADD folks I know, this unhealthy kind of mental stress can actually be painful and require neurochemical self-calming if the game or activity is to be continued. But that doesn't mean the stress is gone - just masked.


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Edit: additions for clarity and for spelling.
 
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