Hello there.
Yesterday, i started to feel nausea, i vomitted multiple times, i had diarrhea, i am weak, i am cold and my heart rate is near 90-100. I also have pain in my stomach. So, i did take since some days, 2,4g NAC, 400mg 5HTP, 10grams glycine, 10grams inositol... i feel really weird... i have a lot of pains in the body, totally tired like in an infection, palpitations (90 bpm heart rate)... could it be a serotoninergic syndrome? I stopped everything... my stomach is irritated, i think it comes from here... but my intestine also are upset (diarrhea, from time to time)... i feel hot, i feel cold... i feel like i have brainfog... since glycine highen levels of serotonine, that 5htp is serotonine, etc, did i took too much of it? I would like to balance the excess if so... i also drank some wine yesterday, 1 glass (i felt not so good afterwards).
Possible Side Effects
Glycine :
Glycine supplements are generally considered safe if taken as directed. With that said, there has been little research into the long-term safety of glycine supplements.
Most people who take glycine will not experience any side effects. Those who do may have mild gastrointestinal symptoms such as an upset stomach, nausea, loose stools, or vomiting.
You may experience stomach irritation as a side effect of L-glycine 1. Stomach-related side effects include nausea and vomiting, which may lead to a temporary decrease in your appetite.
If stomach irritation persists or becomes severe, seek care from your medical provider.
NAC :
Stomach Irritation
The most common side effects associated with orally-administered NAC supplements are stomach-related. You may feel nauseated, vomit or develop diarrhea or constipation, RxList warns. These side effects may contribute to loss of appetite, stomach cramps or bloating. Avoid taking this supplement on an empty stomach to limit or prevent stomach irritation. If stomach discomfort persists, seek additional care from your physician.
Fatigue
You may feel unusually fatigued while receiving treatment with NAC supplements, Memorial Sloan-Kettering Cancer Center (MSKCC) reports. Increased fatigue may negatively affect your ability to remain alert and attentive during your daily activities. If fatigue becomes bothersome, consult your doctor.
livestrong, verywell
Generally, i was taking them with a lot of water, etc. But, yesterday at night, i was in a rush and i took 4grams of glycine, 2 NAC (1,2g) and 4grams inositol, with, IMO, not enough water... could it be the cause? Or is it the excess of serotonine? Also, i did test to puff a cigarillo, to see the taste, as i offered them to my woman... i did take the supplements at 9pm and i did puff at 1am... the symptomes (nausea, the need to vomit and a general weakness state, came maybe near 1:30am... or so... i also drank more sparkling water than before, with lemon juice... i also was upset yesterday and angry, because of an ocd, and everything i get angry, i feel really really bad and i have the feeling my body is filling with a stress and that a mess is being done... also, i did eat near 00:40am, because i was feeling bad... maybe this is the association of all these facts that caused the state i am in now, since...
I remember that Dr Braverman had a list a symptoms
Signs and Symptoms of Too Much Serotonin
according to
livestrong
Mild Symptoms
Someone with too much serotonin may experience a variety of mild symptoms, including diarrhea, nausea, vomiting, headache and shivering. The affected individual may become agitated, restless, uncoordinated or confused. He may develop goose bumps and a rapid heart rate. The muscles may twitch and the pupils may dilate. He may sweat heavily and develop rapid changes in blood pressure.
Severe Symptoms
If the levels of serotonin become extremely high, even more pronounced and dangerous symptoms may occur. This can include a high fever and irregular heartbeat. In some cases, the person may fall unconscious or have a seizure. Serotonin syndrome can be fatal if left untreated once serious symptoms develop.
The mild ones ressemble mines... but, i can not make a direct deduction... Taking GABA promoting supplements (inositol) would ease the problem? How to balance such symptoms?
I also can't stand still... it is said that benzodiazepines are used to treat the agitation...
Prevention and treatment
It consists of stopping the medication, sedation and cooling the patient4. 4 Sometimes cyproheptadine, a serotonin receptor antagonist, is needed in moderate to severe cases. 3 An important combination treatment is agitation control through benzodiazepine sedation.
wikipedia
I have benzos, i took 12,5mg of seresta... but i don't know what to do more... i take infusion, etc etc, for the diarrhea, etc.
Well, thank you, and sorry to 'impose' that...
Peace.