Roundworms that inhabit animals and most importantly humans as parasites can be extremely detrimental to the health of their hosts. Often, host immunity is altered by proteins secreted by the parasite, allowing the parasite to thrive inside of the host (Harcus et al. 39). According to the Raven and Johnson Biology textbook, there are around fifty species of nematodes that are normal human parasites (Raven et al. 746).
Hookworms- These roundworms are found in warm regions and burrow through skin they come in contact with. Their hook shaped anterior ends allow them to latch onto the intestinal wall of their hosts and feed on blood. They routinely suck more blood from the intestinal wall than they need and this can lead to anemia in the host (Raven et al. 746).
Pinworms (Enterobius)- These nematodes are a less serious parasite that inhabit the intestinal tract of humans in the same way that hookworms do. The often cause irritation and disturbances in sleep (Kucik 4). Despite being very widespread and affecting as much as 30% of children and 16% of adults, pinworms can be easily controlled by drugs (Raven et al. 746).
Ascaris (Intestinal Roundworm)- These nematodes are found exclusively in humans and are present mostly in unsanitary areas without modern plumbing. Around one in six people worldwide are infected by Ascaris (Raven et al. 746). A study conducted in Cameroon focused on school children and found that 65.5 % were infected with Ascaris parasitic roundworms. Ascaris eggs are spread through feces, and, when ingested, hatch and bore through the intestinal wall. They move to the heart, the lungs, and finally out the breathing passages where they are swallowed, thus perpetuating the cycle. Females lay hundreds of thousands of eggs each day and can reach nearly 30 centimeters in length (Raven et al. 746).
Trichinella- This nematode is responsible for the most serious roundworm-caused disease, which is known as trichinosis. They live in pigs’ intestines and produce young that make their way to muscle tissue and form tough cysts. Interestingly, nurse cells that aid in parasite growth in the cyst contain two different types of cytoplasm ("Microbiology..." 74). When uncooked pork is ingested by humans, the roundworms cause trichinosis, which can sometimes be fatal. This parasite is also found in bears. In the United States it is suspected that almost two and a half percent of the population has are infected with trichinosis (Raven et al. 746).
Filaria- This type of roundworm causes serious problems in the tropics where it can lead to filiarisis, a condition that affects some 250 million people across the globe. In extreme cases, filiarisis can lead to elephantiasis, which is a grotesque swelling of the legs and other extremities due to worms blocking the lymphatic system. In areas that are abundantly populated with these nematodes, settlement is all but impossible (Raven et al. 746). In developing countries like Sri Lanka where filariasis is most common, morbidity control clinics play a key role in disseminating information about treatment and prevention (Chandrasena et al. 6).
According to T.L Heitman and his colleagues, studies conducted on mice have shown that several factors affect the transmission and abundance of parasitic nematodes. Specifically, caloric intake and energy play a huge role in a host's ability to combat parasites and utilize immunity. Hosts that are deficient in protein and other essentials for good health are much more susceptible to parasitic nematodes, because they are less able to fight their transmission (Heitman et al. 1767).
As a result of all the study of nematode parasites, considerable progress has been made in preventing infections and curing them when they occur. For example, universal insecticides known as Bacillus thuringiensis (Bt) crystal proteins have recently been found to affect many free-living nematodes as well as a species of parasites in rats. This kind of crystal protein is expected to prove effective in controlling most parasitic nematodes in vertebrates (Wei et al. 2760).
