If it were me, I'd at least take some anti-histamine (Benadryl or Claritin, both available OTC). Benadryl tends to make most people sleepy though. That should reduce most of the swelling within 48 hours. Also topical hydrocortisone for the itch (also OTC).
I've never heard of Lyme Disease being transmitted by spider bites, never the less, a round of antibiotics is not a bad idea if you can get some.
I've never heard of Lyme Disease being transmitted by spider bites, never the less, a round of antibiotics is not a bad idea if you can get some.