Astaxanthin cures cancer, chronic inflammation and many other things?

[Z...]

This guy is biochemist who claims he cured terminal severe cancer in 30 days.
His explanation is pretty compelling:

I do have many questions. He is saying there are some animals that never get cancer - like elephants, sharks and mole rats. I heard about mole rats and sharks, not elephants anf need to verify this. He does not explain how these widely different species get access ti astaxanthin.

I tried taking astaxanthin while back and it gave me bad diarrhoea so I backed off.
His form is glycinated and is better delivered which should solve this.
He recommends taking High Sensitivity CRP test to establish right dose.

And here are all the publications about astaxanthin role in cancer

Cancer

https://pubmed.ncbi.nlm.nih.gov/10798217/Antitumor activity of astaxanthin and its mode of action - PubMed (nih.gov) https://pubmed.ncbi.nlm.nih.gov/10470126/A comparison of the anticancer activities of dietary beta-carotene, canthaxanthin and astaxanthin in mice in vivo - PubMed (nih.gov)...

valasta.net

And here is another interview

 

[Z...]

Obviously these days everyone who claims they have solution for a problem is trying to sell you something so that is always a reason to be suspicious.
Maybe I am too jaded but this guy seems to have ties with PTB and military so that is a slight red flag.

 

[Z...]

I found this regarding elephants:

Elephants rarely get cancer, with cancer mortality rates estimated at less than 5%, compared to up to 25% in humans.
This remarkable resistance is primarily attributed to evolutionary genetic adaptations, specifically the possession of 20 copies of the TP53 gene (a tumor suppressor), whereas humans have only one.

Key Reasons for Elephant Cancer Resistance:

• TP53 "Guardian of the Genome": Elephants have 20 copies of this gene, allowing them to produce more p53 protein, which detects DNA damage and repairs it or kills the cell.
• "Zombie" Gene (LIF6): When activated by p53, a unique gene called LIF6 creates proteins that destroy damaged cells before they can become cancerous.
• Cell Self-Destruction: Elephant cells are highly sensitive to DNA damage and prefer to self-destruct (apoptosis) rather than risk repairing the mutation and turning cancerous.

Key Reasons for Elephant Cancer Resistance:

• TP53 "Guardian of the Genome": Elephants have 20 copies of this gene, allowing them to produce more p53 protein, which detects DNA damage and repairs it or kills the cell.
• "Zombie" Gene (LIF6): When activated by p53, a unique gene called LIF6 creates proteins that destroy damaged cells before they can become cancerous.
• Cell Self-Destruction: Elephant cells are highly sensitive to DNA damage and prefer to self-destruct (apoptosis) rather than risk repairing the mutation and turning cancerous.

Regarding Astaxanthin:
While some limited, specialized research (e.g., in podcasts) has suggested that certain antioxidants like astaxanthin might be found in animals with low cancer rates, the primary, widely accepted scientific consensus, published in journals like JAMA and Cell Reports, links the elephant's cancer resistance specifically to their unique genetics and TP53 gene copies.

In summary, elephants are not immune to cancer, but their evolution has provided them with a highly robust, multi-layered genetic defense system that makes them uniquely resistant, rather than relying on a specific dietary supplement like astaxanthin.

Sharks and Cancer

The misconception that sharks are immune to cancer was popularized by the 1992 book Sharks Don't Get Cancer. However, this is scientifically untrue: both benign and malignant tumors have been documented in more than 40 species of sharks and their relatives.

The myth has led to a dangerous alternative medicine trend where people consume shark cartilage supplements, based on the flawed logic that if sharks don't get cancer, consuming part of a shark will protect humans.

Mole rats

Naked mole rats possess extreme, near-total cancer resistance, living up to 30+ years without developing the disease due to unique biological mechanisms
. They produce high-molecular-weight hyaluronan (HMW-HA), a "super sugar" that prevents cell overcrowding and tumor formation. They also exhibit, at minimum, a two-tier mechanism to halt premature cell growth, effectively stopping tumor progression at early stages.


Key reasons for this resistance include:

• High-Molecular-Weight Hyaluronan (HMW-HA): University of Rochester found that this substance, found in their tissues, is five times larger than in other mammals, acting as a "cage" that prevents cancer cells from proliferating.
• Cellular "Contact Inhibition": Science | AAAS explains that their cells are highly sensitive to contact, stopping division when they become too crowded (early contact inhibition).
• Efficient DNA Repair: PubMed Central (PMC) indicates that their bodies have superior DNA repair mechanisms, which reduces the accumulation of mutations over their long lives.

So we can at least debunk his claim that these animals are "cancer resistant" due to astaxanthin .