AUTOIMMUNE DISEASES CAUSED BY AN INFECTION?

[gottathink]

How I see it is that it’s all information, and illness is a manifestation of information. We can challenge it various ways and sometimes the best way is through a physical act, medication or supplement because that introduces into the problem the best medium to deliver the new encoded information. At other times it requires an information through a different optimal medium, such as our beliefs or an energy blockage that would be cleared by a reiki session for example.

 

[gottathink]

Hello,

My contributions may be ignored for now but in the future will be recognized. I understand that the general conception of what causes health and what causes disease are perceived by most to be highly complex and difficult to understand. I would say that this is true but not for the reasons most think.

I recently published a book called "How to Cure any Illness: What your doctor doesn't understand about health".

Everything in the physical is a product of the "mental" or you could say, consciousness. If you truly have one of these "auto-immune disorders", you have beliefs that are instructing your body to turn on itself.

I discovered this having been extremely ill, near death, for many years, with no doctors having any clue what was wrong with me. It led me down a 7 year path of discovering much esotreric information and secrets about health and disease as I eventually discovered how to cure myself.

I'm not saying the things about diet and inflammation that you're focusing on are bad, more so that it's just misplaced. You have inflammation because of your beliefs. You can do things that will ease the inflammation like adjust the diet, but the underlying problem remains.

A massive part (though not the whole part of this) of what I came to understand is that when we suppress our emotions, this creates an energetic blockage in the body which eventually leads to some sort of manifestation of illness. Personal authenticy plays a key role in this:-being true to oneself is a vital aspect of being healthy. What you should find is that the big issues in your personal life, your biggest problems, whatever they may be, these are the things about yourself that you need to heal. Once you decide to be honest with yourself and confront these issues that you've been avoiding, the illness will disappear. (This is not the only cause of illness, we're also in a loosh farm with all sorts of weird multi-dimensional aliens implanting AI into us and disrupting our bodies, and we are poisoned from every direction which I'm sure most all here reading this do know. The body can clear the poisons, it is your own beliefs and emotions that are the primary cause of most illnesses.)

Sorry if that's not extremely specific. I wrote a whole book about it and I can only summarize so much in a quick post but I can answer anybody who might have questions.

These ideas are well explored on this forum; stress, energy blockages, beliefs and emotions contribute to disease. So your contributions will not be ignored. There is general agreement that to heal ourselves and be well requires a lot of deep individualised personal work.

 

[Gaby]

Here's the piperacillin research for those in regions where there are stealth infections transmitted by tick bites. As usual, Serena from this thread has a good quote for it.

An intro:

An Overlooked Antibiotic Shakes Up the Lyme Disease Debate

In a pair of new studies, one unexpected drug eliminated Lyme bacteria at doses 100x lower than standard antibiotics — without wrecking the gut microbiome.

www.vigilantfox.com

In a pair of studies published recently in Science Translational Medicine, scientists showed that piperacillin—a Food and Drug Administration-approved antibiotic—cleared Lyme infections in mice at doses up to 100 times lower than those of doxycycline, the current first-line treatment.

Unlike doxycycline, piperacillin targets the Lyme disease bacteria specifically, sparing the gut microbiome from the disruption that typically accompanies doxycycline use.

“What was remarkable to us was how well piperacillin worked at really low doses,” Brandon L. Jutras, a professor in the microbiology-immunology department at Northwestern University Feinberg School of Medicine and lead researcher, told The Epoch Times. “We don’t need to provide it at a concentration that could kill other microbes.”

Piperacillin works by interfering with the unique way Borrelia burgdorferi, the bacterium responsible for Lyme disease, builds its cell walls—a process essential for bacterial survival.

Because of this targeted mechanism, researchers believe piperacillin will spare the gut microbiome, which is often disrupted by broader-spectrum antibiotics like doxycycline. However, whether this more targeted approach could help prevent PTLD wasn’t addressed in the study.

Jutras’s team screened nearly 500 FDA-approved drugs, tracking how each compound affected the bacterium’s ability to build its distinctive cell wall.

“We could literally watch what happened to the cell wall when we added antibiotics,” Jutras said. “Piperacillin disrupted that process in a way that was incredibly specific to Borrelia.”

Link to the original study: The antibiotic that takes the bite out of Lyme

The relevant graph from the study. In short, anything from 0.2 mg per kilo per day, maximum 1 mg per kilo per day, and it doesn't affect the microbiome.

Figure 5.. Low doses of piperacillin treat murine Lyme disease without impacting the microbiome.
(A) C3H mice were needle inoculated with 104 B. burgdorferi cells. Twenty-one days later, animals were treated with effective doses (see table 2) of either piperacillin, piperacillin-tazobactam, doxycycline, ceftriaxone, or diluent control for seven days. At different stages during or post treatment, fecal samples were collected, genomic DNA purified, and 16S deep sequencing was performed to determine the phylogenic abundance and complexity driven by each treatment. Dosages are shown in milligrams of drug per kilogram of animal weight per day (m/k/d). Samples were collected pre- and post-treatment (p.t.). (B) Shannon index values of results attained in A.

 

[Persej]

Woman With 3 Autoimmune Diseases Enters Remission After Immune 'Reset'

A patient with three different autoimmune diseases has entered complete remission after undergoing an experimental treatment that effectively reset her immune system.

The 47-year-old woman in Germany previously required daily blood transfusions to manage her conditions, two of which affected her blood cells.

She was given Chimeric Antigen Receptor (CAR-) T cell therapy, which involves extracting a sample of immune cells, 'supercharging' them against a specific target, and returning them to the body.

Within weeks of treatment, the patient's symptoms improved, and she no longer requires blood transfusions, even almost a year after the therapy.

"The treatment was extremely efficient in getting rid of all three autoimmune conditions at once," says Fabian Müller, hematologist at the University Hospital of Erlangen in Germany.

"After being sick for more than a decade, the patient is now in treatment-free remission and able to return to an almost normal life. This therapy significantly improved her quality of life."

The patient's primary condition was autoimmune hemolytic anemia (AIHA), a rare disease that occurs when the immune system begins to attack the red blood cells.

She was later also diagnosed with two related autoimmune diseases. The first was antiphospholipid antibody syndrome (APLAS), in which immune cells mistakenly attack tissues, leading to blood clots. The second was immune thrombocytopenia (ITP), where immune cells attack platelets, the small cell fragments that prevent excessive bleeding.

This trio of conditions meant the patient needed blood transfusions every day, and had to regularly take blood-thinning medication to prevent clots. Over the years she had undergone nine different types of treatments to try to improve her health and quality of life, but none had worked for very long.

In the new study, the patient received CAR-T cell therapy, which is increasingly showing promise in treating a variety of cancers. Rather than using chemicals or radiation to kill off cancerous cells, this treatment uses the body's own immune system, teaching it to hunt down a specific target more effectively.

The team behind the work had also previously tuned CAR-T cell therapy to fight other autoimmune diseases, including more than five lupus patients who all went into remission.

In this case, the patient's problems all seemed to stem from B cells, which produce antibodies as part of an adaptive immune response. Her B cells, however, had gone haywire and were instructing the rest of her immune system to attack healthy red blood cells, platelets, and other tissues.

So, the researchers isolated her T cells and engineered them to attack a protein called CD19, which is found on the surface of B cells. They were then infused back into the patient's bloodstream, where they could get to work killing off her rogue B cells.

And sure enough, her health began to improve almost immediately after just a single infusion of CAR-T cells. Seven days after the treatment, she no longer needed blood transfusions.

"After discharge at day 10, the patient experienced a rapid and remarkable increase in physical strength and has been able to carry out normal everyday activity," the researchers write in a paper describing the trial.

By day 25, biomarkers indicated that she had entered complete remission. Her hemoglobin levels returned to normal after being greatly depleted – this protein is found on red blood cells, so its increase indicated that those cells were no longer being destroyed.

Her platelet counts stabilized, and antibodies that trigger blood clots also fell and eventually became undetectable.

"After more than 10 years of illness, the patient's blood counts normalized within just a few weeks. The speed and depth of the response was remarkable," says Müller.

After 322 days, the patient's B cells began to return, but, importantly, almost all of them were 'naive,' meaning they didn't retain immune memory and therefore weren't attacking healthy cells.

Around that same time, the patient was able to stop taking the drugs to prevent blood clots, without any signs of new clots forming. No other negative side effects of the treatment were noted.

Some of her biomarkers remain slightly elevated compared with those of healthy patients, but these could be lingering effects of her many prior treatments, the team says.

While a single case study can't confirm that the therapy will work for every patient, the results are very promising. The scientists note that further controlled clinical trials are needed.

"We believe that using CAR-T therapy earlier for patients with severe autoimmune disease could help prevent complications from years of ineffective treatments," Müller says. "If we can intervene sooner, we may be able to stop the disease process, avoid organ damage, and give patients their lives back."

Woman With 3 Autoimmune Diseases Enters Remission After Immune 'Reset'

A patient with three different autoimmune diseases has entered complete remission after undergoing an experimental treatment that effectively reset her immune system.

www.sciencealert.com

It sounds remarkable, but unfortunately it's very expensive.

CAR T-cell therapy is highly expensive, with the cellular product alone costing $300,000–$475,000 in the U.S.. Total treatment costs, including hospitalization and monitoring, frequently exceed $500,000–$1 million per patient.