I'm planning to use some oral DMSO to help treat my psoriasis. Years ago I considered the possibility but stopped myself after reading this:
Almost all of the psoriatic patients exhibited marked improvement at the end of the first week, but after the period of from ten days to two weeks, we no longer treated psoriatics with DMSO, as the results were disastrous. One patient required hospitalization of an exfoliative erythroderma, and most of the others exhibited a sudden generalized psoriasis of the guttate type. Posttreatment biopsies of psoriatic lesions showed marked accentuation of the histologic features of psoriasis.
However, lately I've been wondering why this would happen and why other cases reported positive results. I'm thinking it may have something to do with
the Koebner phenomenon. Simply put, some people with certain skin deseases may see their disease extend to new areas, or worsen, whenever their skin gets damaged for any reason (I can indeed testify to this). And as we know, DMSO can in fact cause more or less strong irritation if insufficiently diluted. So that could easily explain why some people had disastrous results with an excessive concentration and why some cases report very good results, including when dmso was used in conjunction with topical corticosteroids which would suppress the koebner phenomenon, right?
So, since DMSO seems effective in reducing intestinal permeability among other things, I think I'll start with 1 tsp in half a glass of distilled water (so, sufficiently diluted to avoid any possible irritation) once a week, separate from any other substance by at least 45-60 minutes, and see how it goes. Should that prove insufficient I'll think about trying a highly diluted application on the skin. I'll report the results (although I'm also doing a number of other things at the same time, from the diet to Lugol to a number of other supplements, including some to kill any potential candida overgrowth along with biofilm destroyers, so it'll be hard to say what exactly is working, if anything).
Of course if anyone has any advice, like, for example, other substances to take along with dmso that would most assuredly be safe in my condition (I was considering taking a little lugol along with it, for example, but I'm erring on the side of caution for now), I'm always open to it.