Fentanyl

Keit said:
Well, apparently Prince died from an overdose of Fentanyl:

The Latest: Autopsy: Prince Died of Fentanyl Overdose


A Minnesota medical examiner says Prince died of an accidental fentanyl overdose.

The report from the Midwest Medical Examiner's Office was issued Thursday, more than a month after the music superstar was found dead at age 57 at his Paisley Park mansion.

The single-page report said Prince "self-administered fentanyl," referring to a synthetic opioid many times more potent than heroin.

The report was signed by Quinn Strobl, the office's chief medical examiner.

"(...) But it has been reported that he had hip surgery in the mid-2000s and may have still be in pain."

http://www.nytimes.com/2016/06/03/health/what-is-fentanyl.html?_r=0

In the mid-2000s? Was his pain so great that nothing since the surgery mitigated it? I'm wondering if every drug he took failed and then someone came up and offered him this all-powerful and effective Fentanyl...
 
latulipenoire said:
Keit said:
Well, apparently Prince died from an overdose of Fentanyl:

The Latest: Autopsy: Prince Died of Fentanyl Overdose


A Minnesota medical examiner says Prince died of an accidental fentanyl overdose.

The report from the Midwest Medical Examiner's Office was issued Thursday, more than a month after the music superstar was found dead at age 57 at his Paisley Park mansion.

The single-page report said Prince "self-administered fentanyl," referring to a synthetic opioid many times more potent than heroin.

The report was signed by Quinn Strobl, the office's chief medical examiner.

"(...) But it has been reported that he had hip surgery in the mid-2000s and may have still be in pain."

http://www.nytimes.com/2016/06/03/health/what-is-fentanyl.html?_r=0

In the mid-2000s? Was his pain so great that nothing since the surgery mitigated it? I'm wondering if every drug he took failed and then someone came up and offered him this all-powerful and effective Fentanyl...

As for the bolded part, latulipenoire, some people live with such pain for a very long time, and drugs types and strengths can increase incrementally as their pain increases (often with age), so you may likely be correct about this, if it was the cause, that his drugs kept failing him and he escalated to Fentanyl.

Very sad if true, which it may well be.
 
voyageur said:
latulipenoire said:
Keit said:
Well, apparently Prince died from an overdose of Fentanyl:

The Latest: Autopsy: Prince Died of Fentanyl Overdose


A Minnesota medical examiner says Prince died of an accidental fentanyl overdose.

The report from the Midwest Medical Examiner's Office was issued Thursday, more than a month after the music superstar was found dead at age 57 at his Paisley Park mansion.

The single-page report said Prince "self-administered fentanyl," referring to a synthetic opioid many times more potent than heroin.

The report was signed by Quinn Strobl, the office's chief medical examiner.

"(...) But it has been reported that he had hip surgery in the mid-2000s and may have still be in pain."

http://www.nytimes.com/2016/06/03/health/what-is-fentanyl.html?_r=0

In the mid-2000s? Was his pain so great that nothing since the surgery mitigated it? I'm wondering if every drug he took failed and then someone came up and offered him this all-powerful and effective Fentanyl...

As for the bolded part, latulipenoire, some people live with such pain for a very long time, and drugs types and strengths can increase incrementally as their pain increases (often with age), so you may likely be correct about this, if it was the cause, that his drugs kept failing him and he escalated to Fentanyl.

Very sad if true, which it may well be.

Very sad indeed, voyageur. Somehow this terrifying scenario came to me while reading about his death, his despair and pain, even though I'm not acquainted with his life and work. I explained to myself that he seemed not the type to indulge in drugs if not in (perceived or not) extreme necessity.
 
Here is part of the Fentanyl problem?

6 Execs from Pharma Co. who Lobbied for Illegal Pot, Arrested for Bribing Docs to Push Deadly Fentanyl
http://thefreethoughtproject.com/6-execs-insys-lobbied-weed-illegal-fentynal/

December 10, 2016 - Insys Therapeutics, the company who makes insane profits from a drug behind one of the worst overdose epidemics in the nation’s history, fentanyl, is in hot water — again.

According to Reuters, six former Insys Therapeutics Inc executives and managers were arrested on Thursday on charges that they engaged in a nationwide scheme to bribe doctors to prescribe a drug containing the opioid fentanyl, U.S. prosecutors said.

Along with the executives, Michael Baich, the former CEO, was also charged in an indictment filed in federal court in Boston this week.

They have all been brought up on charges of racketeering for their scheme.

“Patient safety is paramount, and prescriptions for these highly addictive drugs, especially fentanyl, which is among the most potent and addictive opioids, should be prescribed without the influence of corporate money,” Carmen M. Ortiz, the United States attorney in Massachusetts, said in a statement. “I hope that today’s charges send a clear message that we will continue to attack the opioid epidemic from all angles, whether it is corporate greed or street-level dealing.”

What makes this information so damning and hypocritical is that in September, the Free Thought Project helped to expose Insys Therapeutics for paying hundreds of thousands of dollars to keep marijuana, a plant that has never killed anyone, illegal.

That’s right, in a glaring display of hypocrisy, the maker of the drug Subsys, a sublingual fentanyl spray, claims that marijuana is dangerous because it could hurt children. At least that was their public reasoning for shoving $500,000 towards a campaign opposing marijuana legalization in the US.

These people not only advocated that pot is dangerous, but they were bribing doctors to prescribe a drug responsible for one of the most deadly epidemics in the history of the United States — for entirely unnecessary reasons.

About 129 people died each day nationwide in 2014 from a drug overdose and more than half of those were opioid, heroin, or fentanyl related, according to the DEA.

Insys has every reason in the world to despise legal weed as multiple studies now show that it is a great alternative for pain relief versus the highly addictive and deadly opioids.

According to a study that looked at 17 states with medical cannabis laws in place, researchers “found that the use of prescription drugs for which marijuana could serve as a clinical alternative fell significantly, once a medical marijuana law was implemented.”

Prescriptions fell dramatically for opioid painkillers, with 1,826 fewer doses being prescribed per year by the typical physician in a medical cannabis state. Amazingly, the trend also applied to prescriptions for depression, seizure, nausea and anxiety.

Insys has other reasons to fear this beneficial plant as well — because they are making a synthetic version of it.

According to a September report by the Intercept, Insys is currently developing a product called the Dronabinol Oral Solution, a drug that uses a synthetic version of tetrahydrocannabinol (THC) to alleviate chemotherapy-caused nausea and vomiting. In an early filing related to the dronabinol drug, assessing market concerns and competition, Insys filed a disclosure statement with the Securities and Exchange Commission stating plainly that legal marijuana is a direct threat to their product line:

Legalization of marijuana or non-synthetic cannabinoids in the United States could significantly limit the commercial success of any dronabinol product candidate. … If marijuana or non-synthetic cannabinoids were legalized in the United States, the market for dronabinol product sales would likely be significantly reduced and our ability to generate revenue and our business prospects would be materially adversely affected.

It is apparent that the people at Insys are willing to go to extreme and unscrupulous lengths to maintain their market share — up to and including buying off doctors and politicians, as well as pushing a highly dangerous drug on people who may not need it.

According to the indictment of the executives, as reported by the NY Times, the six former employees, including the former chief executive, Michael L. Babich, and regional sales directors, offered bribes and kickbacks to pain doctors in various states in exchange for getting them to prescribe more of the company’s product, Subsys, a spray form of fentanyl. Subsys is supposed to be used only by cancer patients who are already on round-the-clock pain drugs.

The irony about the government’s choice to indict these Insys executives is that they are a small time company who has very little market share. If we compare Insys Therapeutics to the makers of OxyContin, for example, we can see a glaring difference as to how the two companies are treated by the government.

While Insys sits in court awaiting a much-deserved criminal indictment, the makers of OxyContin, the Sackler family, is rubbing elbows with the elite.

As the DEA cracks down on fentanyl, the FDA announced last year that they approved the use of OxyContin, a similarly deadly drug, for use in children.

So, while the news of Insys getting busted for pushing their deadly drug on people who don’t need it is certainly worthy, the elite who make billions a year from peddling their deadly addictive drugs through pill mills across the US while fighting to keep cannabis illegal, remain quietly protected by the establishment and their immoral war on drugs.
 
Was paying attention to a couple of things related of late. The first is that a new (old) drug that is said to be 100 x more potent than fentanyl, is making its presents known. This drug has some extra retooled molecules and is called Carfentanil (veterinarians will understand this).

http://www.cbc.ca/news/canada/ottawa/carfentanil-ottawa-paramedics-drug-1.3885569

A drug called carfentanil, an animal tranquillizer that's 100 times stronger than fentanyl, is so dangerous Ottawa paramedics are being warned to wear masks on the job.

Carfentanil has now been detected in drugs sold on the streets in Ontario.

Green pills seized last month in the Waterloo, Ont., region contained the potentially lethal opioid, Health Canada confirmed. Yesterday, Toronto police also warned they found carfentanil in heroin sold on city streets.

"From Toronto it's going to make its way here in a week or two or three," expects Ottawa Paramedic Service spokesperson J.P. Trottier.

"This is a huge concern for us."

The drug is commonly used at zoos to sedate large animals. In humans it's so potent it has been linked to the deaths of 15 people in Alberta and one overdose in Vancouver.

Ottawa paramedics have been watching the crisis unfold out west over the past year in an effort to prepare first responders. Staff are being briefed on how to treat patients and stay safe themselves by wearing masks whenever possible.

"Even a few grains can be dangerous to someone's health," said Trottier.

Carfentanil can come in powder form. It's so potent that just breathing in the same room as the drug can cause an overdose, Trottier warned, adding paramedics often don't know if there are drugs involved when they arrive at a scene.

"It's just powder," he said. "Basically you walk by, you brush up against where the powder has been and it becomes airborne just like dust."

"There have been cases in the U.S. where the carfentanil has affected a few police officers. Paramedics, when they arrived at scene, had to treat the officers for an overdose. They inhaled the airborne carfentanil."

'We really need to flood the market with naloxone'

Organizers behind an Ottawa program that provides social and medical services for drug users are also "very concerned" carfentanil could be headed east.

For the past two months, staff with the OASIS program at the Sandy Hill Community Health Centre have been handing out as many naloxone kits as possible to drug users at risk. Naloxone is a drug that can temporarily reverse the effects of an opioid overdose.

We really need to flood the market with naloxone at this point and have as much available out there as possible," said program director Rob Boyd. "This drug is a much more lethal drug than even the powdered fentanyl we've been concerned about all along."

Carfentanil's high concentration means even medical kits that contain two doses of naloxone may not be able to save lives, Boyd said.

"That's not going to be enough. We're hearing some reports from B.C. emergency departments where there have been some cases where people have been administered eight or nine doses."

Recreational drug users also at risk

People who take drugs recreationally at weddings or bars may also be at risk of a carfentanil overdose, according to Ottawa Public Health.

In partnership with Ottawa hospitals, paramedics, and pharmacist associations, the agency launched a campaign last month to warn anyone using counterfeit opioids that they may be cut with other drugs.

"We know [carfentanil] is being cut into other drugs and it's really hard to detect {I read about a Winnipeg lab that is working on blood detection for carfentanil that needs to be in the parts per trillion measure they said}. So it's really important to get the message out to people," said Kira Mandryk, supervisor for the Ottawa Public Health harm reduction team.

More than 200 pharmacies in Ottawa dispense free naloxone over the counter.

Health officials are also encouraging people to call 911 if they overdose, not to just use the treatment kit, Mandryk said.

The other thing (and I don't have a link as it was a radio show), was a discussion from street producers of these drugs who discussed the next wave of drugs that may make these fentanyl type drugs look lame, if that is possible. I don't recall what class of drug these were, yet they were highly synthetic and toxic - and becoming more available.

I'll reserve any tin-foil hat thinking, yet these drugs that seem to be manufactured and distributed so easily, and are getting stronger by the day and are taking out families.
 
Here they are hiking property taxes to pay for the extra costs fighting the fentanyl crisis.

http://bc.ctvnews.ca/vancouver-approves-property-tax-hike-to-fight-fentanyl-crisis-1.3201787

From the very beginning I had suspicions about this crisis. How it appeared all of a sudden, with vague origins, ( mostly conveniently China), and no real questioning of the how's and why's of it appearing like it did. It would not seem beneficial to the pushers to sell something that would kill off its customers. And how did all the pushers get this idea all at the same time?
 
Fentanyl is becoming more and more of an issue in the "recreational" drug use realm as well. A social worker friend of mine was recently at a lunch and learn about fentanyl. It is being cut with drugs such as cocaine and even marijuana, as it is relatively cheap to buy from china and makes these other drugs even more addictive. There have been numerous "overdoses" of cocaine laced with fentanyl and causing death. Awareness is Key. Sadly those whom use drugs most likely know the hazards associated and still choose to "try" or continue using it. As with the high potency of this particular opioid, death can be around the corner the first time one tries it. I worry about the young teens and the peer pressure to try drugs!! :(
 
Hello H2O said:
Here they are hiking property taxes to pay for the extra costs fighting the fentanyl crisis.

http://bc.ctvnews.ca/vancouver-approves-property-tax-hike-to-fight-fentanyl-crisis-1.3201787

From the very beginning I had suspicions about this crisis. How it appeared all of a sudden, with vague origins, ( mostly conveniently China), and no real questioning of the how's and why's of it appearing like it did. It would not seem beneficial to the pushers to sell something that would kill off its customers. And how did all the pushers get this idea all at the same time?

I suppose one should not dismiss the historical facts of the inner city crisis's when heroin, cocaine and later crack and such was funneled in by the PTB - see an example here: https://www.sott.net/article/219914-CIA-Introduced-Crack-Cocaine-To-Americas-Inner-Cities-In-The-1980s

This may or may not be the case, yet it has been crossing my mind a little as it did seem to very suddenly explode upon the scene from out of nowhere (while the finger points to China, the media says).

Whatever the case, it's damn sick.
 
http://journal-neo.org/2017/01/05/solutions-or-scapegoating-straight-talk-about-china-fentanyl-2/


Solutions or Scapegoating? Straight Talk About China & Fentanyl
Column: Locations

The crisis of opiate addiction is very real in the United States. In 2015, more Americans died from drug overdoses than gun violence. According to the Washington Post: “Opioid deaths continued to surge in 2015, surpassing 30,000 for the first time in recent history… That marks an increase of nearly 5,000 deaths from 2014. Deaths involving powerful synthetic opiates, like fentanyl, rose by nearly 75 percent from 2014 to 2015.” (https://www.washingtonpost.com/news/wonk/wp/2016/12/08/heroin-deaths-surpass-gun-homicides-for-the-first-time-cdc-data-show/?utm_term=.ed97d04e8ab4)

Who is to blame the crisis? Almost all experts agree that roots of the crisis began in the 1990s when American pharmaceutical corporations began pushing pain-killer medications, and encouraging doctors to over prescribe them, hoping to drive up their profits. The US Center for Disease Control is now urging physicians across the USA to reduce the use of painkillers, as their chronic over-prescription in the last decades has been fueling the crisis. (https://www.cdc.gov/media/releases/2016/p0315-prescribing-opioids-guidelines.html)

The problem of overuse of painkillers was further exacerbated by the NATO invasion of Afghanistan in 2002, which resulted in a huge boom in poppy production across the country. The poppy fields of Afghanistan are now flooding the global market, driving the price of heroin lower than ever.

Predictably, certain voices in America’s for-profit media have chosen not to blame powerful money hungry drug companies pushing their products or US “regime change” operations overseas for the epidemic which is destroying so many American lives. Instead, they have found a convenient scapegoat, the People’s Republic of China.

The basis for blaming China for the heroin epidemic is the claim that Fentanyl, a synthetic opiate, is increasingly prevalent across the United States and used by opiate addicts. Because a lot of legal, medical Fentanyl is manufactured in Chinese factories, it is somehow deduced that the drug is being intentionally pushed onto the United States by a cabal of evil Chinese scientists, Chinese gangsters, or the Communist-led Chinese government itself, and that this sinister conspiracy originating on the other side of the planet is somehow the cause of the opiate crisis. This dark fairy tale, a great example of “fake news” or a conspiracy theory if ever, simply does not add up when basic facts about the heroin crisis and China are considered.

Fentanyl: Not A “Chinese Drug”

First of all, Fentanyl is not a “Chinese Drug” as certain voices have tried to label it. Fentanyl was invented by an Italian scientist named Paul Janssen. Janssen started his work at the University of Cologne in Germany, but it was while he was working in Belgium that he invented the synthetic opiate which was eventually introduced for medical use as a painkiller. Janssen’s Belgian drug company, that introduced Fentanyl to the world as a legal, pharmaceutical product was eventually bought out by Americans. Today, the drug inventors who brought Fentanyl into the world have been absorbed into the Wall Street “Fortune 500” medical giant known as“Johnson & Johnson.”

While a lot of legal, medical Fentanyl is manufactured in mainland China, like the United States, China has outlawed all non-medical use of the substance. Narcotics trafficking is punishable by death in China, and international bodies commonly criticize the People’s Republic for how harshly its anti-drug laws are enforced. US and Chinese drug enforcement officials routinely cooperate in efforts against drug cartels. Bill Brownfield, the US assistant secretary of state for international narcotics and law enforcement has stated: “I actually believe on matters of narcotics and drugs, the US and China cooperate extremely well.” (http://usa.chinadaily.com.cn/us/2016-03/09/content_23803950.htm)

Rarely is Fentanyl ever used by itself for recreational purposes. Pure Fentanyl is certainly used in hospital rooms and by those prescribed it for chronic pain, but when Fentanyl is used recreationally by addicts, it is almost always mixed with non-synthetic, poppy derived heroin. Dealers will cut heroin with Fentanyl as a method of saving money, and expanding their inventory.

In 2014, a total of 31,271 people in the United States died from opiate overdoses. Only 4,200 of those deaths, less than 14% actually involved Fentanyl, and in almost every single case, the Fentanyl was mixed in with other, non-synthetic poppy-based opiates. Recreational drug users who consume Fentanyl do so by accident, thinking they are consuming pure heroin. (http://www.vox.com/science-and-health/2016/12/20/14005776/deaths-pain-drug-opioids-fentanyl-chart)

While the DEA suspects that some of the chemical components necessary to create Fentanyl often originate in China, statics show that a lot of Fentanyl is being manufactured in the United States. Across the country, police have noticed a rise of domestic manufacturing of synthetic opiates. After all, synthetic opiates do not require poppy fields, smuggling units, or any of the other more risky aspects of the drug world. Anyone with the proper chemicals and a laboratory can create synthetic opiates. When making Fentanyl, no poppy fields or Chinese people are required in the process.

Domestic Fentanyl production facilities have been found across the United States. For example, near the post-industrial city of Syracuse New York, a lab for creating synthetic opiates was discovered inside what looked like a typical family home, just a few blocks away from a local YMCA. The police found over 6,000 doses in the house, along with $4000 in cash. (http://www.syracuse.com/crime/index.ssf/2016/03/sheriff_cheaper_drug_50x_stronger_than_heroin_hits_syracuses_suburbs.html)

China’s Revolution “Wiped Out” Drug Addiction

The xenophobic narrative about China, the primary culprit in the epidemic of addiction plaguing the United States, is just not consistent with reality. Yes, it is easier to blame “the yellow peril” or the “red dragon” on the other side of the world for crisis plaguing middle America, which was wrought by greed and militarism among our own population. However, reality tells a different than story.

Prior to 1949, China was one of the most heroin and opium addicted societies in the world. The British empire famously waged two “opium wars,” forcing the Emperors to allow the importation of narcotic substances. The first US military intervention on the Chinese mainland was done in 1900 when the US Marine Corps was sent to crush a group of Chinese nationalists called “the boxers” who were lynching drug dealers and saw drug addiction as a scourge imposed on their country by foreign imperialists.

The Chinese Communist Party effectively wiped out drug addiction on the mainland during the first years of the People’s Republic. The public was mobilized in a mass campaign to fight against substance abuse. According to “Opium: A History” by Martin Booth “When the Communists took over, Mao Zedong wiped out opium and addiction. China was clean for over forty years with only pharmaceutical opium being produced.” (https://books.google.com/books?id=HXGzAAAAQBAJ&pg=PA305&lpg=PA305&dq=Mao+Wiped+Out+Opium&source=bl&ots=HQapUVBkQ8&sig=vginBGnYnTIhJpyAZgLyS-D7YNw&hl=en&sa=X&ved=0ahUKEwjv9oqPrJjRAhUh4YMKHWYKC1k4ChDoAQgdMAE#v=onepage&q=Mao%20Wiped%20Out%20Opium&f=false)

The term “brainwashing” is derogatory in the United States, but it originally referred to the Communist Party’s process of rehabilitating criminals, anti-communists, drug addicts, prostitutes, and others after the 1949 revolution. A more accurate translation of the term is “thought reform” and after China’s revolution, the government effectively rehabilitated millions of people who they argued had been criminalized under the old society.

While there has been a slight revival of China’s drug problem in recent years, the problem facing China is exponentially smaller than what it faced in the period preceding the birth of “New China” in 1949. An article from the LA Times in 1990 described anti-drug efforts by the Chinese government reporting that: “Opium addiction, once widespread in China, was virtually wiped out after the 1949 Communist revolution.” The article goes on to quote Beijing Youth News which proclaimed: ““This devil, stamped out years ago, has reappeared in our country like a ghost… It has not yet generally spread, but it will bring disaster if we don’t stop it.”

Drugs & De-Industrialization

When Chinese Communists speak of their history, they refer to the scourge of drug addiction not as moral failing on the part of recreational users or even as random medical calamity befalling unfortunate individuals. In China’s narrative of history, drugs were something imposed on the country by foreign bankers and western monopolists. Drugs served the purpose of weakening China’s people, making them subservient, and preventing them from developing their own, independent economy. While opium and heroin addiction is no longer prevalent in China, steel manufacturing, high speed trains, advanced computer systems, and satellites are.

In the de-industrialized rust belt of the United States, many Americans voted for Donald Trump because they hoped he would fix the economy, and make the US once again a booming center of industrial production with a rising standard of living. It is these very de-industrialized midwestern states that have been hardest hit by the heroin crisis, as well as suicide, mental illness, and other “diseases of despair” associated with an overall decline in living standards.

Rather than blaming China for the drug problems, perhaps we should learn from the methods used by the Chinese people to wipe out drug addiction, and raise millions of people out of poverty. If history shows us anything, it is that solutions are a thousand times more valuable than scapegoats.
http://journal-neo.org/2017/01/05/solutions-or-scapegoating-straight-talk-about-china-fentanyl-2/
 
I've been helping a 95 yr. old woman who is on a Fentanyl patch continuely. Yesterday she was emmited to the hospital as she was very disoriented and unable to function in the simplist of acts. Tests where preformed for stroke etc. but nothing was discovered. I wonder if her problem could be associated with this drug. She has been on it for quite awhile so maybe a tolerance is possible and wouldn't contribute. She has been very worried about a few things lately and was getting sick so possibly a lowered immunity response could make her more susceptible to this drug. I don't know, thought I'd throw it out here if anyone has an idea on it :huh:
 
SummerLite said:
I've been helping a 95 yr. old woman who is on a Fentanyl patch continuely. Yesterday she was emmited to the hospital as she was very disoriented and unable to function in the simplist of acts. Tests where preformed for stroke etc. but nothing was discovered. I wonder if her problem could be associated with this drug. She has been on it for quite awhile so maybe a tolerance is possible and wouldn't contribute. She has been very worried about a few things lately and was getting sick so possibly a lowered immunity response could make her more susceptible to this drug. I don't know, thought I'd throw it out here if anyone has an idea on it :huh:

Summerlite, in the past I have read about a Fentanyl patch getting wet and releasing overdose amounts.
 
Thank you NMA, that's good to know. The patch she uses is plastic with gel inside and sticky around the edges to hold it in place so not easily made wet. She did come home from the hospital with a new fabric patch and I could see how this could become wet easily and perhaps cause a problem. After returning home for one day she is back in the hospital again due to suddenly hallucinating intensely. I've never seen anything like it. So now her medications are being reevaluated. Hopefully the problem will be discovered and remedied.
 
Hello Summerlite, the 95 year old may have been imbibing a substance which enhances the effect of the drugs she is taking, for instance pineapple. This is a known drug enhancer. Tasty, but can be dangerous in combination.
FWIW
 
Thats a good thing to know MusicMan. Her diet is usually the same and I've never seen her eat pineapple, a lot of Cheetoes though! I'll see what kind of list there is for foods like that. Thanks
 
Hello again Summerlite, just to correct my previous, apparently the offender is grapefruit, not pineapple, I'm always confusing the two, but best to be aware of the possibilites of an overdose when combining with foods, especially with drugs like fentanyl. The fruits contain enzymes which can effect absorption rates of the drugs, depending on the metabolism of the patient.
(Pineapple contains Bromelain, which is a type of anti-inflammatory)
 
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