Fluoridated drugs syndrome goes deeper.

[Charles]

Study Indicates Antidepressants Double Risk Of Bone Fracture

As I am not allowed more than 1500 characters in the body of comments I would like to use the opportunity of this forum to further elaborate.

Deej had the following comment:

What popped out at me was that more than one of the listed antidepressants had at least one flouride atom attached to the structure. Doing a little research, it looks like all but one of the listed drugs has flouride in it - only the structure of Paxil doesn't appear to contain flouride.
If I recall correctly, it's well-documented that flouride has a very strong affinity for bone tissue and has the effect of making bone (and tooth) structure more brittle and prone to breaking.
I'd like to see a comparative study of the rates of bone fracture in meds with flouride and those without.

It is also the first thing that popped up in my mind Deej.

I knew about fluoride having a very high bonding affinity for hydroxy-apatite – which is about the exact same thing that makes up the crystal structures within bone.

I also knew already how most anti-depressants were having fluorine as part of their molecular structure.

Also, half of the statins to lower cholesterol, by the way, are having the same disease, in that the fluorine atom becomes an integral part of the molecule that is the basis within these medicines. In relation to the statins, it was hard for me to belief that the "gainers" had put the cut-off-line (I first wrote lie :D ) THAT low that 25% of the population I am part of, is urged by doctors to take statins because their cholesterol is decided to be too high. Many of them are taking it.

So the jump was easily made with bones becoming brittle.

And then, on a second thought, I realized that the way I started to see the phenomenon of fluoridated and/or chlorinated hydrocarbons came from an entirely different angle. This is what particularly aroused me in this article.

And thinking further along this line I came to realize that the amount of ionic (or inorganically ‘bound’) fluoride being taken is already at huge levels today. At least in Europe (but I am not entirely sure) you can read the mg/l of it being present in lots of ‘mineral waters’. It is a lot.

I can not imagine that people who are on prozac (fluoxetine) for instance would get that high amount of fluoride within their system, as they would get already in an inorganic kind of form.

So what is my angle to it?

Neither chlorinated nor fluoridated hydrocarbons are being used in nature. So what is it doing in our medications? (over there in the US you call these ‘medications’ ‘drugs’, and what we call "drugs" , you call "dope" :) )

Why are they there ??? Chlorine? Fluorine?

I am pretty convinced by now that those chlorine and fluorine atoms became part and parcel of the thing that ‘does’ it, to change the local electro negativity for instance. This "does it" because it creates local binding possibilities within these molecules so that they can all of a sudden bind extremely well with lots of other organic molecules, and more particularly proteins.
Also the reverse happens. You can also create local areas within these molecules that have a very high localized hydrophobicity (it doesn’t like water). And then, all of a sudden you end up with molecules that can drive that hydrophobic branch deep within the hydrophobic pockets of certain proteins, with the result of very firm binding.

And POOF, you have a ‘provable effect’, which can always be turned into some ‘therapeutic effect’. Dollars!!! Or Euros!!! And ahhh, we have been investing so much already.

And so, in their blindness, willful or not, they 'forget' that with such molecules you will evidently have increased binding, but that such happens in a very indiscriminate way. Ergo, there will be an entire list of secondary effects because it binds to so many more proteins for instance.

And that is why after giving it a second thought, I came to realize that the effect of "bones becoming brittle" could very well be indirectly, because those ‘medications’/drugs interfere with another process by binding to known (or unknown) proteins.

It is also possible of course that those medications are metabolized in a way that does give them high affinity for bone.

Evidently, as you say, Deej
studies are needed.

In the mean time, I have warned myself about those things.

 

[Petey of Lone Tree]

I recall reading somewhere in the "Cassies/SoTT" literature that a moderate amount of vinegar will help neutralize the effects of fluoride in water. Part of my daily regiment now includes a shot of vinegar in 8 oz. of water. 'Twas kinda ghastly-tasting to start with, but I've almost gotten used to it.

Any readers remember the exact quote I'm referring to?

 

[Guest]

Session 970705:

A: Fluoride is toxic, and deposits in fatty tissues, and lymph system. Aside from the obvious possible negative consequences, it can make one more susceptible to electromagnetic wave frequencies that are designed to make one open to mind alteration!
Q: (L) Okay. You have my undivided attention. How does he get the fluoride out of his system?
A: Recommend daily ingestion of Goldenseal root, as well as vinegar and garlic in moderation, along with up to an hour per every two days of light aerobic exercise.


The most important thing is the exercise, which will naturally reduce fat (aka, the fatty tissue buildup of fluoride.) and cleanse the lymph system. I take the Goldenseal and get excellent results. Vinegar and garlic are normal parts of my diet and they are quite yummy (best way to imbibe vinegar is through salad dressing mixed with herbs and oil.).

 

[Alana]

(best way to imbibe vinegar is through salad dressing mixed with herbs and oil.)

And that's where crushed garlic goes too :)

 

[Keit]

Salad dressing:

1 spoon of Balsamic vinegar
1 teaspoon of Dijon mustard
1 spoon of soy sauce
3 crushed garlic
3 spoons of Olive oil
Sult as much as you like (remember that soy is already salty)

Goes best with lettuce+sherry tomato or just tomato+baby salad greens+walnut and feta cheese ;)

 

[Charles]

I think that Golden-seal is an important part in the formula for getting rid of INORGANIC fluoride.
Vinegar, with moderation! , was another part of it. Moderate exercise too.

The advice was given in a session for Ark as he got too much inorganic fluoride from bottled water
(Was it in Dijon ?) and that the water actually had an exceptionally good taste.

First and foremost, one should evidently try not to let it enter ones body.

Also, this was to get rid of inorganic fluoride, and is irrelevant to my post.

So what was the core message again?

I will try to formulate the core message in a different way, but I first need some spare time ...

 

[Charles]

The pharmaceutical industry is essentially a spin-off from the petrochemical industry, one that can be traced right back to those charlatans selling snake-oils that supposedly could grow ones hairs back. And hear who is usually accusing the alternative healers of being quacks?

The nature of carbon chemistry is such that it allows making very complex molecules. One can end up with molecules that happen to have a very high binding affinity with certain proteins, so that these proteins no longer do what they are supposed to do such as binding of metabolic molecules (inhibition of enzymatic activity), or hormones and neurotransmitters and such, or are no longer able to bind other proteins. There’s a plethora of possibilities but ideally, in case you want to end up with a pharmaceutical product, one would have 1) a useful therapeutic effect and 2) a very high specificity in that the molecule does not bind other proteins, as this would result in side effects, and 3) slow biodegradation.

If you contemplate a hormone such as oestradiol for instance it becomes evident why there are such highly specific and also high binding affinities between the complex oestradiol molecule on the one hand and certain receptor proteins on the other hand, as those latter happen to have evolved precisely to this end. It is very much the key and lock principle.

Ideally you would have an occasional nitrogen or oxygen atom, or amino groups, or carboxyl groups and such as these functional groups can offer additional binding mechanisms by means of ionic bonds, or hydrogen bridges and so forth.

The pharmaceutical industry however goes beyond the use of functional groups that are encountered AND used in nature. We see that lots of pharmaceutical products are molecules wherein chlorine and fluorine atoms become an integral part of the molecule.

If you take hydrocarbons and you add chlorine gas you end up with chlorinated hydrocarbons and hydrochloric acid. If you then add HF (hydrogen fluoride) you replace the chlorine substituents with fluorine.

See for instance: http://en.wikipedia.org/wiki/Hydrochloric_acid under the heading organic synthesis.

Again, you don’t encounter this in nature. That already is cause for prudence, I think. But there is more.

Fluorine's relatively large electronegativity and small atomic radius gives it interesting bonding characteristics, particularly in conjunction with carbon. The covalent radius of fluorine is very small (about 60 picometers) and is also highly variable. It decreases for instance if it has formed a covalent bond that tends to become ionic (both fluorine and the bonding partner each adopt a local charge). It also decreases if the coordination number decreases: a fluorine atom in CF3 will appear bigger as one in CF.

If we now look at the structure of prozac which is supposed to inhibit the uptake of released serotonine by specific proteins, so that it can be transported back into the cells,

we see how the tri fluoro carbon group is shining at the bottom of this drawing. Much like Teflon, is it not.

We also see that the molecule is not really very complex.

So from where does it derive its binding affinity ??

Almost each and every protein has hydrophobic patches and parts along its polypeptide chain. As the polypeptide chain folds in its most probable thermodynamic configuration to form the 3D protein, these hydrophobic patches turn away from the watery medium, and thus end up on the inner side of the protein.

The CF3 group placed as in Prozac can be considered as a hydrophobic (lipophilic) tentacle that will want to insert within a hydrophobic pocket somewhere at the inside of a protein. Such anchorage will result in a high binding affinity between the molecule and the protein. It’s just that such will not necessarily result in a high specificity. Many more proteins will be prone to be bound by such molecule.

In the next propaganda piece you can learn more.
"Why fluorine is an invaluable tool in medicinal chemistry." www(dot)teknoscienze(dot)com/images/documenti/supplements/ins.%20articoli.pdf
While reading, remember also to read for yourself about the (possible) consequences.

I forgot to add that the first reason why fluorine ended up in pharmaceutical compounds was to protect them from biodegradation. Again this would exclude the possibility of fluorinated compounds becoming metabolized towards inorganic fluoride for instance, and thus also excludes this as a possible mechanism to explain why bones are becoming brittle.

Because of the difficulty of biological systems in dealing with metabolism of fluorinated molecules, fluorinated antibiotics and antidepressants are among the major fluorinated organics found in treated city sewage and wastewater.

http://news.bbc.co.uk/1/hi/health/3545684.stm

 

[Charles]

By shear luck (or maybe serendipity?), I found this …

http://www(dot)quantumconsciousness.org/overview.html

I work as an anesthesiologist, and routinely erase and restore the consciousness of my patients. The anesthetic gases I administer pass through the lungs, into the blood and brain where they localize in tiny pockets inside certain neuronal proteins. The critical proteins whose disrupted function causes anesthesia/loss of consciousness include tubulins as well as various membrane protein receptors. The tiny intraprotein pockets where anesthetics bind are "hydrophobic" regions, nonpolar areas where the dynamics of the proteins are controlled by quantum forces called van der Waals London forces. Unlike any other drugs, anesthetics act only by these same extremely weak quantum mechanical London forces, apparently preventing/impairing normally occurring London forces whose collective coherence is necessary for consciousness.

Notice his very similar wording: “The tiny intraprotein pockets where anesthetics bind are "hydrophobic" regions …

Notice that this is not about the prozac molecule, or cholesterol lowering drugs (statins). He talks about molecules that knock out consciousness (anesthetics). So let’s see how these molecules (anesthetics) look like.

From the same link www(dot)teknoscienze(dot)com/images/documenti/supplements/ins.%20articoli.pdf

(yours will no longer work, mine neither, but I printed it out)

some examples of inhaled anaesthetics:

Fluoroxene:
CF3 – CH2 – O – CH = CH2

Halothane
CF3 – CHBr - Cl

Isoflurane
CF3 – CHCl – O – CHF2

Desflurane
CF3 – CHF - O – CHF2

Sevoflurane

CF3
|
CF3 – CH – O – CH2 – F


Isn’t THAT amazing that the same CF3 group (trifluoro carbon) as present in the prozac molecule pops up in every of those molecules that knock out consciousness when inhaled?

 

[notanothermonday]

Just think this is only one of many different toxins we are exposed to in our environment. It is well known that it is difficult to fully understand how one drug is going to impact an individuals body chemistry and physiological processes. Then add to this the fact that most people who are using pharamceuticals are using more than one and now there are so many more possiblities for negative interactions between the drugs as well as the environmental stresses that are encountered daily and on top of that genetic variation and expression.
As a doctor (not your conventional MD) I have seen patients come in with heavy metal toxicity (mercury is a big one). They are a neurological mess. After cleaning up diet and taking products that are designed to help the body rid itself of heavy metals these people have recovered. I mention mercury because up until a few years ago this was, as I am sure many of you are already aware, used extensively in vaccinations.
I am well aware that Mercury is a neurotoxin which makes it, in my mind, a potential culprit for manipulation of people. Does anyone have any research or thoughts on this matter?


Thanks

 

[Simmi]

Anyone have any comments on using reverse osmosis to supply flourine free water?

I am very interested to find out if anyone has looked into this.

 

[Charles]

Simmi,

you can find a lot about fluoride overhere (mostly the inorganic form). You will find something in the Aspartame thread that relates to the use of reverse osmosis to get rid of inorganic fluoride. We do have a tendency to go off on a tangent at times :)
http://www.cassiopaea.org/forum/index.php?topic=3155&p=4



Notanothermonday,

you will find some information that relates to ORGANIC mercury administered as thymerosal (a "common" preservative in vaccines).

A possible link for autism has been discussed here.
http://www.cassiopaea.org/forum/index.php?topic=830

And how it degrades the immune system by inhibiting dendritic cells, and triggers auto-immune diseases by deregulating interleukin 6 secretion has been discussed over here.
http://www.cassiopaea.org/forum/index.php?topic=829

To find more, you could try the search BUTTON.

 

[notanothermonday]

thank you

 

[Simmi]

Thanks Charles.

 

[Ringo]

The advice was given in a session for Ark as he got too much inorganic fluoride from bottled water
(Was it in Dijon ?) and that the water actually had an exceptionally good taste.

I didn't think flouride was added to bottled water? I've not seen it listed on the label.

 

[mudrabbit]

Ringo wrote:
I didn't think flouride was added to bottled water? I've not seen it listed on the label.

It is added to bottled water, but not all bottled waters. What bugs me to no end is that they add flouride to distilled water and call it "nursery water".
peg