Insomnia

Mgse said:
Thanks for the tips to everyone. Yesterday night was like the other nights (sweating, awake most of the time, 1-2h of dreaming), took 1 melatonin (2.5mg) and 3x110 mg of magnesium citrate (not sure how much magnesium). I did another round of blood tests (hepatitis, bacteria, testosterone levels etc), urine test (culture) yesterday (results in 5 days) and thursday I'll do an ecography for the liver, at least to narrow down the possible causes. My right leg numbness is better, but my sleep hasn't improved much. I'm not sure if I'm still in the detox process, a bit constipated again (I drink 2l of water), anxious and worried about not sleeping. I followed your tips about diet, but there is some kind of imbalance (hormonal, chemical) or organ dysfunction, where the melatonin is not produced properly to induce the sleep (maybe too much cortisol, saliva test is needed). While trying to sleep I see a pattern, after melatonin has its effect, I start dreaming and then 1/2-1 h later I wake up suddenly with heart palpitations and sweating (my body temp increases rapidly) lasting 2-3min, maybe my body temp lowers to much while dreaming, or it's a sleep apnea (I snore, my wife told me). Then I cannot go to sleep again until 4-5 am where I start dreaming again (1/2h), probably my body is too tired. Benadryl might help, is there anybody else that tried it. I did EE breathing yesterday, but stopped at Ba-ha because my hands started to shake. I'm trying to find a reasonable explanation for an aid to help my body rest for a couple of hours because we know when our bodies get rested.

I'd consider upping your does of magnesium, especially right before bed. I'd wage that 330mg of magnesium isn't an effective dose considering the amount of physical stress you've been experiencing.

Definitely be vigilant about screens too late into the evening as someone else here as suggested, it can really cause a mess. Taking the melatonin and not respecting other aspects of the pre-sleep routine likely will produce undesired results.



Have you read the Magnesium Miracle? I myself haven't (yet), however, from my understanding on the material I have read, it is imperative for optimal health and can be a trigger for many things if you become deficient. Which just about all of us are. There may be much more going on that is beyond my understanding.

From Magnesium Miracle
The Recommended Daily Allowance (RDA) for magnesium is between 350 and 400 milligrams per day, which is just enough to ward off outright deficiency. But for optimal health and for the twenty-two conditions that are triggered by magnesium deficiency, perhaps twice as much magnesium is needed. One of the highest sources of magnesium is kelp, but one tsp. only has about 30 milligrams. One tablespoon of almonds has 33 milligrams. Because we probably don’t get nearly enough magnesium from out diet we have to investigate magnesium supplements.



Magnesium Deficiency Triggers or Causes The Following Conditions:

1.) Anxiety and Panic attacks- Magnesium (Mg) normally keeps adrenal stress hormones under control.
2.) Asthma- Both histamine production and bronchial spasms increase with Mg deficiency.
3.) Blood clots- Mg has an important role to play in preventing blood clots and keeping the blood thin-much like aspirin but without the side effects.
4.) Bowel disease- Mg deficiency slows down the bowel causing constipation, which could lead to toxicity and malabsorption of nutrients, as well as colitis.
5.) Cystitis- Bladder spasms are worsened by Mg deficiency.
6.) Depression-Serotonin, which elevates moods, is dependent on Mg. A Mg-deficient brain is also more susceptible to allergens, foreign substances that can cause symptoms similar to mental illness.
7.) Detoxification- Mg is crucial for the removal of toxic substances and heavy metals such as aluminum and lead.
8.) Diabetes- Mg enhances insulin secretion, facilitating sugar metabolism. Without Mg insulin is not able to transfer glucose into cells. Glucose and insulin build up in the blood causing various types of tissue damage.
9.) Fatigue- Mg-deficient patients commonly experience fatigue because dozens of enzyme systems are under-functioning. An early symptom of Mg deficiency is frequently fatigue.
10.) Heart disease- Mg deficiency is common in people with heart disease. Mg is administered in hospitals for acute myocardial infarction and cardiac arrhythmia. Like any other muscle, the heart muscle requires Mg. Mg is also used to treat angina, or chest pain.
11.) Hypertension- With insufficient Mg, spasm of blood vessels and high cholesterol occur, both of which lead to blood pressure problems.
12.) Hypoglycemia- Mg keeps insulin under control; without Mg episodes of low blood sugar can result.
13.) Insomnia- Sleep-regulating melatonin production is disturbed without sufficient Mg.
14.) Kidney Disease- Mg deficiency contributes to atherosclerotic kidney failure. Mg deficiency creates abnormal lipid levels and worsening blood sugar control in kidney transplant patients.
15.)Liver Disease leading to liver failure- Mg deficiency commonly occurs during liver transplantation.
16.) Migraine- Serotonin balance is Mg-dependent. Deficiency of serotonin can result in migraine headaches and depression.
17.) Musculoskeletal conditions- Fibrositis, fibromyalgia, muscle spasms, eye twitches, cramps and chronic neck and back pain may be caused by Mg deficiency and can be relieved with Mg supplements.
18.) Nerve problems- Mg alleviates peripheral nerve disturbances throughout the whole body, such as migraines, muscle contractions, gastrointestinal spasms, and calf, foot and toe cramps. It is also used in treating central nervous symptoms of vertigo and confusion.
19.) Obstetrics and Gynecology- Mg prevents Premenstrual Syndrome; prevents dysmenorrhea (cramping pain during menses); is important in the treatment of infertility; and alleviates premature contractions, preeclampsia, and eclampsia in pregnancy. Intravenous Mg is given in obstetrical wards for pregnancy-induced hypertension and to lessen the risk of cerebral palsy and Sudden Infant Death Syndrome (SIDS). Mg should be a required supplement for pregnant mothers.
20.) Osteoporosis- Use of calcium with Vitamin D to enhance calcium absorption without a balancing amount of Mg causes further Mg deficiency, which triggers a cascade of events leading to bone loss.
21.) Raynaud’s Syndrome- Mg helps relax the spastic blood vessels that cause pain and numbness of the fingers.
22.) Tooth decay- Mg deficiency causes an unhealthy balance of phosphorus and calcium in saliva, which damages teeth. Material excerpted from Dean, Carolyn. The Miracle of Magnesium (2003 Ballantine Books: New York, NY), 2003. pp. 5-7.

I bolded some stuff that stood out to me in relation to your symptoms.

Keep us updated. Hope you start feelin' better.
 
It really sounds to me that your nervous system received a shock, possibly due to an allergic reaction to the drug, and it has induced some kind of permanent imbalance and even neuropathy (numb leg). Personally i don't think it's mere anxiety. I went through many anxiety states, chronic and acute, but none of them matched what you describe. It's true that anxiety is able produce psycho-somatic symptoms of almost any kind but they're a result of being over-conscious of one's body and they wouldn't wake you up in the middle of the night (after you manage to fall asleep).

Still think you should try out supplementing NAC. I'd also consider ALCAR (acetyl-l-carnitine) and ALA (alpha-lipoic acid). They won't harm for sure, and can help. There are many articles, papers and posts describing successful usage of these supplements in treatment of neuropathies and toxic effects from drugs. You may want to look them up.
 
I actually wanted to chime in about magnesium. I know it helps lots of people to relax and sleep. And it does for me too, up to a point at least. I was taking magnesium bisglycinate. Then I started waking up half a dozen times at night. I know from before that for me, some supplements taken in too big doses tend to do the opposite of what they are supposed to do. So I did a search online and found many testimonies of people having stopped taking magnesium as it kept them awake. Magnesium's ability to relax seems to be dose-dependent and some people might need to keep under a certain level. So I quit and after 3 to 4 days, I started sleeping soundly again. I need to add that I used to be an insomniac and I might be especially sensitive in that respect.

Testimony on Paleohacks said:
If magnesium did have a causal negative impact it could be due to your individual neurotransmitter regulation. Magnesium is NMDA antagonist and GABA agonist, and both neurotransmitters are important for the modulation of sleep. Just as some people respond quite differently to caffeine, I imagine one could respond differently to magnesium.

Testimony on Paleohacks said:
From what I read, excess magnesium will lower the level of calcium and may lead to a calcium deficiency with some symptoms similar to calcium excess. Deficiency of calcium leads to insomnia, anxiety, palpitations, weak immune system, fatigue, low blood pressure, difficulty swallowing. You can try taking calcium and see if it solves your magnesium insomnia. For me it made me calm at first then it exacerbated the symptoms. The magnesium-calcium balance is very delicate and can offset the balance of electrolytes. Magnesium affects potassium levels too.

Just mentioning it in case it could help.
 
Mrs. Tigersoap said:
I actually wanted to chime in about magnesium. I know it helps lots of people to relax and sleep. And it does for me too, up to a point at least. I was taking magnesium bisglycinate. Then I started waking up half a dozen times at night.

Actually, I experienced a similar effect when recently started taking magnesium citrate again before going to sleep. It had such an energizing effect, I was waking up at 5:30 after falling asleep at 23:30. Other people on the net also give similar testimonies.

And if I remember correctly, best to use magnesium malate before sleep, and magnesium citrate or other in the morning.
 
Thanks for all the info. So far, I'm still struggling with the insomnia, lost 12 pounds, now it's been a month, I don't know what else to do. Second round of blood tests looking for hepatitis, HIV and others were negative, the urine test for bacteria negative. I did a liver ecography, the technician said it looks good, waiting for the final results tomorrow. The results for the testosterone test will arrive tomorrow as well. The only way to get a little bit of sleep (2h at most) is to take a melatonin, I'm thinking that antibiotic might caused something in the brain that is not functioning properly anymore. I'm really out of options, agitated, desperate for a solution. I definitely need to sleep, otherwise my health is not getting better. That's way I've contacted Laura to ask the C's what is the root cause of all this and how to get out of it, I know there are other people with more severe issues, but I'm struggling, losing my job, marriage and friends. I can't continue using melatonin, I even developed a tolerance, sweating a lot after waking up. The doctors prescribed me with Zopiclone (sleeping pill), which I refused and I don't want to go that path if possible. I haven't tried Benadryl yet, I don't want to mess my brain with more stuff. I've taken PassionFlower to help with anxiety and calmness and it does help. Laura is it possible to ask the C's about my sleep problem ? I really need your help Laura.

Thank you.
 
lostinself said:
Still think you should try out supplementing NAC. I'd also consider ALCAR (acetyl-l-carnitine) and ALA (alpha-lipoic acid). They won't harm for sure, and can help. There are many articles, papers and posts describing successful usage of these supplements in treatment of neuropathies and toxic effects from drugs. You may want to look them up.

Yup. Good advice.
 
L-carnitine might have the opposite effect or other side effects:
_http://forums.phoenixrising.me/index.php?threads/problems-with-acetyl-l-carnitine.15642/_

I'm gonna try ALA. Thank you.

Laura said:
lostinself said:
Still think you should try out supplementing NAC. I'd also consider ALCAR (acetyl-l-carnitine) and ALA (alpha-lipoic acid). They won't harm for sure, and can help. There are many articles, papers and posts describing successful usage of these supplements in treatment of neuropathies and toxic effects from drugs. You may want to look them up.

Yup. Good advice.
 
Psychological research over three decades demonstrates the power of Stimulus Control Therapy.

Can’t get a good night’s sleep? You’re not alone. In surveys of what would improve people’s lives, a good night’s sleep frequently comes near the top of the list.

Poor sleep results in worse cognitive performance, including degraded memory, attention, performance and alertness. And in the long term insomnia is also associated with anxiety and depression. And people’s sleep gets worse as they get older. After 65 years old, between 12% and 40% of people have insomnia.

All sorts of methods have been tried to combat poor sleep, from drugs through psychological remedies to more outlandish treatments.

The problem with drugs is that they have side-effects and are often addictive. The problem with the more outlandish treatments is that although they tend not to have side-effects, we don’t know if they have any effect at all. Psychological remedies, though, combine the best of both worlds: studies show they work without side-effects.
Stimulus Control Therapy

Professor Richard R. Bootzin has been researching sleep disorders for many years at the University of Arizona Sleep Research Lab. Writing in the Annual Review of Clinical Psychology, he describes the different psychological approaches that have been used to treat insomnia (Bootzin & Epstein, 2011).

Of these the most successful single intervention is called Stimulus Control Therapy (Morin et al., 2006). You’ll be happy to hear it consists of six very straightforward steps. If you follow these it should improve your sleep. After the list I’ll explain the thinking behind them. First, here are their six steps:

Lie down to go to sleep only when you are sleepy.
Do not use your bed for anything except sleep; that is, do not read, watch television, eat, or worry in bed. Sexual activity is the only exception to this rule. On such occasions, the instructions are to be followed afterwards, when you intend to go to sleep.
If you find yourself unable to fall asleep, get up and go into another room. Stay up as long as you wish and then return to the bedroom to sleep. Although we do not want you to watch the clock, we want you to get out of bed if you do not fall asleep immediately. Remember the goal is to associate your bed with falling asleep quickly! If you are in bed more than about 10 minutes without falling asleep and have not gotten up, you are not following this instruction.
If you still cannot fall asleep, repeat step 3. Do this as often as is necessary throughout the night.
Set your alarm and get up at the same time every morning irrespective of how much sleep you got during the night. This will help your body acquire a consistent sleep rhythm.
Do not nap during the day.

Why it works

This method is based on the idea that we are like Pavlov’s drooling dog. We attach certain stimuli in the environment to certain thoughts and behaviours. Famously Pavlov’s dogs would start drooling when a bell rang, because they associated hearing the bell with getting food. Eventually the dogs would drool at the sound of the bell even when they didn’t get any food. Replace the bell with a bed and food with sleep and conceptually you’re there.

If we learn to do all kinds of things in bed that aren’t sleep, then when we do want to use it for sleep, it’s harder because of those other associations.

This is just as true of thoughts as it is of actions. It’s important to avoid watching TV in bed, but it’s also important to avoid lying in bed worrying about not being able to get to sleep. Because then you learn to associate bed with worry. Worse, you suffer anticipatory anxiety: anxiety about the anxiety you’ll feel when you are trying to get to sleep.

So, this therapy works by strengthening the association between bed and sleep and weakening the association between bed and everything else (apart from sex!).

Other treatments supported by the research are progressive muscle relaxation, which is exactly what it sounds like, and paradoxical intention. This latter technique involves stopping people trying so hard to get to sleep. The paradox being that when people stop trying so hard, they find it easier to fall asleep.

All this assumes you don’t live next door to a late night drummer and you’re not downing a double espresso before hitting the sack, but those sorts of things are pretty obvious. Everything else being equal, though, Stimulus Control Therapy seems the easiest for most people to implement.

_http://www.spring.org.uk/2011/05/6-easy-steps-to-falling-asleep-fast.php
 
I find this is also helpful for sleeping:

https://www.youtube.com/watch?v=NCtF9_DuzMU

It's also enlightening to watch her entire videos on posture:

https://www.youtube.com/watch?v=mtQ1VqGGU74
 
Another thing that might be worth looking into is Pantothenic acid (vitamin B5): http://cassiopaea.org/forum/index.php/topic,38646.0.html
 
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