A deficiency of vitamin B12 can lead to inadequate amounts of acetylcholine, an important neurotransmitter involved in learning and memory...
B12 deficiency is not as common as folic acid deficiency, it is more common than people— including most doctors—suspect. Even low normal levels can contribute to depression, particularly in the elderly. ...
Methylation requires S-adenosyl-methionine (SAMe). SAMe is synthesized from the amino acid methionine and dependent on folic acid, choline, and vitamin B12. Methylation detoxifes estrogen, testosterone, thyroid hormones, acetaminophen, and coumarin. ...
Vitamin B12 (cobalamin) is the only B vitamin stored by the body. A vitamin B12 deficiency occurs only in malnutrition, malabsorption, or other impediments to proper digestion. Vitamin B12 is important in the growth of children. It is responsible for the replication of genetic material and so is essential for the
development and maintenance of all the cells. Vitamin B12 helps form the myelin sheath that insulates nerve processes and allows rapid communication from one cell to another A deficiency of B12 can cause a reduction in mental acuity, evidenced by poor memory. Alzheimer’s and senile dementia, two diseases associated with memory loss, confusion, and nerve damage, might both be attributed to a deficiency of B12 It is only found in animal products (especially liver), so vegetarians should supplement it. Antigout medications, anticoagulant drugs, and potassium supplements may interfere with B12 absorption, and taking antacids will block its absorption. Calcium is necessary for normal absorption of B12 High doses of folic acid can mask the symptoms of B12-deficiency anemia. Because vitamin B12 deficiency is routinely seen in the elderly, I believe everyone over the age of 60 should be supplementing with vitamin B12. Vitamin B12 is not toxic.