XPan
The Living Force
(part 1)
Corona Investigative Committee, Berlin
Dr. Sabine C. Stebel | Sitzung 165: Wettlauf mit der Zeit / "Race against time"
July 2023
- - - - - - - - - -
2 h 13 min
Note: Odysee seem to be very slow - or something is amiss with older videos from the Corona Investigative Committee - so i am not sure if the video can be watched at this stage.
An alternative (different video) can be watched with her at Apolut (also in German language) - and that one does play without hiccups. In essence she explains the same, how the CEO (Uğur Şahin) of German Biontech made all the errors you could make, which high school student are taught to avoid...
She obliterates Uğur Şahin's "self heroic" book in every detail... and ignored the basic ground-rules in protein design at all levels.
1h 20 min
Dr Sabine C. Stebel is educated in Direct Protein Evolution & Protein Engineering
Already back in year 2008, Sabine Strebel published a document about Directed Protein Evolution - a model which in essence is already enough to create for example spike proteins (the how to do's). She used this already with her high school students with success at a time, before the students even started to work in labs.
How do you "optimize" a protein ? There are several options how to do this.
The direct approach is called "Directed Evolution"; when you use a gene, then you experiment and select and repeat until you get the results you wish for.
The "Rational Design" is based on assumptions, and then though mutations you experiment and analyze the outcome of these. Both designs can be combined. It is very crucial that when using the "Rational design" (implementation of computer generated snippets) into a protein, you must after over-expression of such protein variants further characterize those - in order to understand the nature of them. If you don't - you do not know what you got ! (Biontech kind of gave a rats a**)''
The nature of these designs is unreliable and you can't truly predict the outcome either. As an example: because of so called "silent mutations", these can spoil the desired outcome of a protein - even if you didn't change the genetic code sequence (!); in other words - you get something you didn't thought of, expected or even got aware of...
It is for example totally unknown if the spike proteins are stable in various environments, temperatures etc. For example, the temperature in a woman's feet can actually go down to just 7°C - and you have to ask yourself - is the/a protein thermostable ? Does it melt ? Does it flock out ? Some proteins maybe thrive between 50 to 70°C, others may flock out at +4°C. All these aspects are crucial to know - but are totally unknown "Denaturation points" (German: "Denaturirungspunkte") revolving the C19 spike proteins. Also questions of how fast or slow a protein's activity is - are total unknowns.
You do not want a protein to denaturing at a temperature of 30°C, given that your body temperature is 37°C. Or to flock out at 7°C, when the feet of a lady can reach such low temperatures.
When a protein is denaturing in a biological body - it get's very nasty ! Both chain nor heat denaturation points of the C-19 spike proteins are totally unknown !
You may already start to get a sense, that as soon you scrape on the glossy surface of Uğur Şahin's heroic "Covid-19 vaccines" (and future modRNA based products), it starts to crumble in so many ways, it is almost ridiculous - as there are huge amounts of vital question, unanswered and unknown. Yet, high school students are taught to determine these things and what to avoid when dealing with Protein Evolution and Protein Engineering...
What does "flocking out" mean ? Well, those proteins can then for example create amyloid clumps and other types of clumps... And surely we have heard about those more than plenty... Such things, should been characterized and identified way before you inject them into living people !
Dr Sabine C. Stebel wrote already 15 years ago:
In other words:
We are way behind in terms of true knowledge, that when exchanging amino acids to know the true outcome of such manipulations. We don't. It would be better to let nature do its thing, and then select among the results of proteins (Directed evolution method, i understand this as) instead of sitting at the computer and create artificial genetic codes ("Rational Design" Method) ... with (in reality) unknown results in real life.
Corona Investigative Committee, Berlin
Dr. Sabine C. Stebel | Sitzung 165: Wettlauf mit der Zeit / "Race against time"
July 2023
- - - - - - - - - -
Dr. Sabine C. Stebel | Sitzung 165: Wettlauf mit der Zeit
Im Gespräch mit Dr. Sabine C. Stebel (Biologin)
odysee.com
Note: Odysee seem to be very slow - or something is amiss with older videos from the Corona Investigative Committee - so i am not sure if the video can be watched at this stage.
An alternative (different video) can be watched with her at Apolut (also in German language) - and that one does play without hiccups. In essence she explains the same, how the CEO (Uğur Şahin) of German Biontech made all the errors you could make, which high school student are taught to avoid...
She obliterates Uğur Şahin's "self heroic" book in every detail... and ignored the basic ground-rules in protein design at all levels.
Interview mit Dr. Sabine Stebel – “Können 100 Ärzte lügen?” - apolut.net
Wer die Naturgesetze nicht versteht oder respektiert, wird am Ende verlieren. Eine politische, juristische oder religiöse Umdefinierung ändert nicht
apolut.net
Dr Sabine C. Stebel is educated in Direct Protein Evolution & Protein Engineering
Already back in year 2008, Sabine Strebel published a document about Directed Protein Evolution - a model which in essence is already enough to create for example spike proteins (the how to do's). She used this already with her high school students with success at a time, before the students even started to work in labs.
How do you "optimize" a protein ? There are several options how to do this.
The direct approach is called "Directed Evolution"; when you use a gene, then you experiment and select and repeat until you get the results you wish for.
The "Rational Design" is based on assumptions, and then though mutations you experiment and analyze the outcome of these. Both designs can be combined. It is very crucial that when using the "Rational design" (implementation of computer generated snippets) into a protein, you must after over-expression of such protein variants further characterize those - in order to understand the nature of them. If you don't - you do not know what you got ! (Biontech kind of gave a rats a**)''
The nature of these designs is unreliable and you can't truly predict the outcome either. As an example: because of so called "silent mutations", these can spoil the desired outcome of a protein - even if you didn't change the genetic code sequence (!); in other words - you get something you didn't thought of, expected or even got aware of...
It is for example totally unknown if the spike proteins are stable in various environments, temperatures etc. For example, the temperature in a woman's feet can actually go down to just 7°C - and you have to ask yourself - is the/a protein thermostable ? Does it melt ? Does it flock out ? Some proteins maybe thrive between 50 to 70°C, others may flock out at +4°C. All these aspects are crucial to know - but are totally unknown "Denaturation points" (German: "Denaturirungspunkte") revolving the C19 spike proteins. Also questions of how fast or slow a protein's activity is - are total unknowns.
You do not want a protein to denaturing at a temperature of 30°C, given that your body temperature is 37°C. Or to flock out at 7°C, when the feet of a lady can reach such low temperatures.
When a protein is denaturing in a biological body - it get's very nasty ! Both chain nor heat denaturation points of the C-19 spike proteins are totally unknown !
You may already start to get a sense, that as soon you scrape on the glossy surface of Uğur Şahin's heroic "Covid-19 vaccines" (and future modRNA based products), it starts to crumble in so many ways, it is almost ridiculous - as there are huge amounts of vital question, unanswered and unknown. Yet, high school students are taught to determine these things and what to avoid when dealing with Protein Evolution and Protein Engineering...
What does "flocking out" mean ? Well, those proteins can then for example create amyloid clumps and other types of clumps... And surely we have heard about those more than plenty... Such things, should been characterized and identified way before you inject them into living people !
Dr Sabine C. Stebel wrote already 15 years ago:
Despite the advances made in understanding protein structure and function this knowledge is by far not sufficient to tailor amino acid exchanges. From this angle it is very appealing to use a random design approach such as combinatorial strategies to sequence space for beneficial mutations without prior knowledge of structure or function.
In other words:
We are way behind in terms of true knowledge, that when exchanging amino acids to know the true outcome of such manipulations. We don't. It would be better to let nature do its thing, and then select among the results of proteins (Directed evolution method, i understand this as) instead of sitting at the computer and create artificial genetic codes ("Rational Design" Method) ... with (in reality) unknown results in real life.