(part 1)

Corona Investigative Committee, Berlin

Dr. Sabine C. Stebel
| Sitzung 165: Wettlauf mit der Zeit / "Race against time"
July 2023

- - - - - - - - - -

🇩🇪 2 h 13 min

Note: Odysee seem to be very slow - or something is amiss with older videos from the Corona Investigative Committee - so i am not sure if the video can be watched at this stage.

An alternative (different video) can be watched with her at Apolut (also in German language) - and that one does play without hiccups. In essence she explains the same, how the CEO (Uğur Şahin) of German Biontech made all the errors you could make, which high school student are taught to avoid...

She obliterates Uğur Şahin's "self heroic" book in every detail... and ignored the basic ground-rules in protein design at all levels.

🇩🇪 1h 20 min

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🔹 Dr Sabine C. Stebel is educated in Direct Protein Evolution & Protein Engineering

🔹 Already back in year 2008, Sabine Strebel published a document about Directed Protein Evolution - a model which in essence is already enough to create for example spike proteins (the how to do's). She used this already with her high school students with success at a time, before the students even started to work in labs.


🔹 How do you "optimize" a protein ? There are several options how to do this.

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🔹The direct approach is called "Directed Evolution"; when you use a gene, then you experiment and select and repeat until you get the results you wish for.

🔹The "Rational Design" is based on assumptions, and then though mutations you experiment and analyze the outcome of these. Both designs can be combined. It is very crucial that when using the "Rational design" (implementation of computer generated snippets) into a protein, you must after over-expression of such protein variants further characterize those - in order to understand the nature of them. If you don't - you do not know what you got ! (Biontech kind of gave a rats a**)''

🔹The nature of these designs is unreliable and you can't truly predict the outcome either. As an example: because of so called "silent mutations", these can spoil the desired outcome of a protein - even if you didn't change the genetic code sequence (!); in other words - you get something you didn't thought of, expected or even got aware of...

🔹 It is for example totally unknown if the spike proteins are stable in various environments, temperatures etc. For example, the temperature in a woman's feet can actually go down to just 7°C - and you have to ask yourself - is the/a protein thermostable ? Does it melt ? Does it flock out ? Some proteins maybe thrive between 50 to 70°C, others may flock out at +4°C. All these aspects are crucial to know - but are totally unknown "Denaturation points" (German: "Denaturirungspunkte") revolving the C19 spike proteins. Also questions of how fast or slow a protein's activity is - are total unknowns.

You do not want a protein to denaturing at a temperature of 30°C, given that your body temperature is 37°C. Or to flock out at 7°C, when the feet of a lady can reach such low temperatures.

When a protein is denaturing in a biological body - it get's very nasty ! Both chain nor heat denaturation points of the C-19 spike proteins are totally unknown !

▪️You may already start to get a sense, that as soon you scrape on the glossy surface of Uğur Şahin's heroic "Covid-19 vaccines" (and future modRNA based products), it starts to crumble in so many ways, it is almost ridiculous - as there are huge amounts of vital question, unanswered and unknown. Yet, high school students are taught to determine these things and what to avoid when dealing with Protein Evolution and Protein Engineering...

🔹 What does "flocking out" mean ? Well, those proteins can then for example create amyloid clumps and other types of clumps... And surely we have heard about those more than plenty... Such things, should been characterized and identified way before you inject them into living people !

Dr Sabine C. Stebel wrote already 15 years ago:
Despite the advances made in understanding protein structure and function this knowledge is by far not sufficient to tailor amino acid exchanges. From this angle it is very appealing to use a random design approach such as combinatorial strategies to sequence space for beneficial mutations without prior knowledge of structure or function.

In other words:
We are way behind in terms of true knowledge, that when exchanging amino acids to know the true outcome of such manipulations. We don't. It would be better to let nature do its thing, and then select among the results of proteins (Directed evolution method, i understand this as) instead of sitting at the computer and create artificial genetic codes ("Rational Design" Method) ... with (in reality) unknown results in real life.
 
FDA says getting Covid shot on same day as certain flu vaccines may raise risk of strokes in elderly people - while children aged 2-5 slightly more likely to suffer seizures after a coronavirus vaccine

And, yet these flu and Covid shots are still being promoted like crazy with no disclaimer of the bad effects/results! Even the friggin' pharmaceuticals massively advertised on TV have minute warnings of side effects, including death! These companies and the compliant government officials and all others responsible need to be sued out of existence and jailed for murder/attempted murder!
 
(part 2)

Corona Investigative Committee, Berlin

Dr. Sabine C. Stebel
| Sitzung 165: Wettlauf mit der Zeit / "Race against time"
July 2023

th-3324658894.jpeg

Directed Evolution model for Proteins
(instead of computer generated genetic code inserts, aka "Rational design")


The Directed Evolution Method has advantages as follow:

1) you do not need to know the structure of the protein
2) You do not need to know nor understand the way how the protein functions
3) you do not need know about how proteins fold
4) You do not need to break your head around the effect a mutation has, or what doesn't work - because the selection of all the aforementioned, falls away in the screening. (as nature only works what nature creates. What doesn't work - doesn't work).

It was claimed that Pfizer/BioNTech used "directed evolution" - but Dr Sabine C. Stebel consider this to be false.

🔹 It is possible by adding Manganese Mg2+ to replace the natural cofactor Mg2+ into the PCR test, which increases error prone results, due to larger amounts of mutations / false readings /reassembling of primer snippets affecting each other (mixed with the DNA from the nose scrapes, because they never cleaned and separated our own natural RNA from Virus RNA).

Of course adding Manganese Mg2+ to PCR can be done deliberately - in order to achieve as many positive results as possible... It would also be a relative cheap method to just add Mg2+ in order to gain more positive PCR results, says Dr Wolfgang Wodarg.

Manganese should NOT be in a PCR test !! And since the PCR test isn't a medical standard, i guess anything goes. And it did... we know this already. In the package leaflet of the Roche PCR test - there was manganese listed, says Dr Sabine C. Stebel.


Basic Rules of Protein Engineering

These are the rules that should be known before you even touch a protein of any kind.

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🔹 But then there is the issue with the so called GenScript Codon Usage Frequencies.

(the database for the codon usage frequencies)

🔹 A codon (there are 64 in existence), if i understood it correctly (?) are the start and ends of a genetic sequence. It is very important that dependent which codon one uses in the creation of those (from yeast, e-coli and other types) - because they have different frequencies, that must or should match the biological organism - otherwise there will be serious stresses.

🔹 the RNA is translated in the ribosomes of the cell. It is here that the protein is built up (transcribed) step by step. Already at this stage (before it is ready to fly), protein folding is happening. The regulation of this process is super crucial. There is a rhythm in how and when a protein is create, that is discarded; combined with various speed, then followed by breaks, and then it continues again... THIS ENTIRE HOW AND WHEN AND HOW FAST TRANSLATION PROCESS IS SUPER CRUCIAL !


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And here comes the kicker...

🔹 If you in any way manipulate the codons (beginnings and endings of RNA code), you are in for some severe problems. Because you get DIFFERENT PRODUCTS coming out (protein), due to the alteration of the codons - which BioNTech did. And they did heavy alterations, which affected the speed (they wanted as many spike proteins as possible, while also as stable as possible codons, and used a code, which in itself is highly mutagenic by design !

So, in the belief of that they created many homogeneous spike proteins coming out of the cell's ribosome apparatus... that is a total illusion. You get in reality, all kinds of protein creations of unknown origin, effects and toxicity. Not necessarily the spike protein you thought you get, but all kinds of (protein) variations - and wrong folded proteins; think amyloids and prions to name a few examples.

And that stuff is created in the bodies of people... And it is found everywhere in the body, including heart and brain.

What could possibly go wrong.

Kind of like... everything !!


🔹 BioNTech CEO Uğur Şahin prides himself, as does Pfizer, in that their Covid-19 "vaccines" can create large amounts of spike proteins after it exits the ribosome apparatus in the human cells. Yet, it is the rapid speed, which ensures that proteins are misfolded... with dire consequences. High school students learn this. Why didn't Uğur Şahin do it ? But yeah, playing the hero in his book.

🔹 BioNTech's "optimized" codons, creating a far more rapid production of "spike proteins", not just creates misfolded prion like proteins (and unknown proteins), but also impaired protein synthetics. Remember that a cell regardless which, still needs to create many other proteins in order to function and to contribute to organ as a whole and ultimately to the body. But the rapid translation of the modRNA in the cell, impairs impair/damages to the ribosome apparatus.

🔹 BioNTech heavily manipulated the codons for speed, and each tiny little (modified) change to the codon - creates different protein variants ! BioNTech does not know what kind of proteins that actually come out of the ribosomes. Idiotic as they are, they even wrote that into their papers. (Phase 1 and 2 trails where conducted with "codon variant 8" [which was used to get approval to be used in humans] - and then they switched to "codon variant 9" in phase 3 [rollout of vaccines] of the BNT162b2 vaccine.

However - both codon variants, result into totally different proteins... 🧐
 
(part 3)

Corona Investigative Committee, Berlin

Dr. Sabine C. Stebel
| Sitzung 165: Wettlauf mit der Zeit / "Race against time"
July 2023

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🔹 Wolfgang Wodarg asks Dr Sabine C. Stibel, if the EMA (European Medical Agency) understood that BioNTech used different codon variants between the trail and the final products, being totally different protein creations ? Well, Uğur Şahin wrote in his book, that the Codon 9 variant which was used in the rollout to people around the world, showed better creation of antibodies. In mice.

What it didn't say was the quality of the antigens, only that more where produced in the codon 9 variant of the C-19 Pfizer "vaccine" and that the reactions in people with the latter version was a lot stronger.

Dr Sabine C. Stibel says to this that

1) i could be because the codon 9 variant produced more antigenes.
2) but it could also be, the protein that was created, was a different one

🔹 She also says, that in reality i could be a matter of three different types of (main) proteins, because the original virus protein - is not the one that got produced in human cells after the injections.

🔹 Pfizer/BioNTech does not know the true expression of the antigen proteins created in humans. They only know the modRNA code they put into the vials - but not the final outcome of those.

Because one single "silent mutation" is enough, resulting into a different protein structure / potency after having gone though the ribosome apparatus !

🔹 Both Pfizer and Moderna screwed around with the codons. A natural spike protein has a GC content distribution of 36%. But Pfizer upped it to 53% and Moderna 61%. It is a telling story of that the manipulation of the codons leading to a more rapid translation of the modRNA code - but get all kinds of protein variants of unknown structure as a result.

_-2023-10-27-at-00.40.52.jpg


Facit:
by manipulating the CODONS ALONE - results into heavily altered proteins - beyond the control of what you would expect !


GENERAL RULES:

🔹 1) There is much evidence that the partial unfolding of proteins via intermediates and intermediate states plays an important role in the regulation of biological functions. Malfunctions in these (miss)folding steps lead to disturbances in the organism and even to diseases.

🔹 2) Mutations in proteins tend to destabilise both the intermediate steps and the original state of proteins. Regions with stability can lead to the misfolding of proteins via the accumulation of partially unfolded intermediates and thus to aggregation and disease.

🔹 3) Proteins are dynamic molecules that have to move compared to their native state in order to be able to function.
Intermediate states are the result of large-scale movements and can therefore shed light on the mechanisms underlying biological function-mechanisms underlying biological function.

🔹 4) Many diseases are caused by the loss of function of proteins, which is caused by mutations that disrupt a binding or active site of a protein or by active site of a protein, or through increased expression levels (production rates) that lead to increased activity of a protein.

Alternatively, however, mutations can cause disease by destabilization of the native structure or stabilization of non-native conformations, which leads to an accumulation of partially folded
intermediates, leading to aggregation of the affected proteins.

🔹 5) Larger proteins (such as the spike protein), whose folding is less cooperative (more prone to disruption and more demanding), are more at risk of aggregating or misfolding.

These 5 principles, in a nutshell, say one thing:

Mutations in a protein have an extremely high probability of irreparably destroying the equilibrium between different protein conformations, which has been optimised over millions of years of evolution, whether during folding or during its biological activity, and thus leading to disease.
 
(part 4)

Corona Investigative Committee, Berlin

Dr. Sabine C. Stebel
| Sitzung 165: Wettlauf mit der Zeit / "Race against time"
July 2023

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🔹 Pfizer / BioNTech do not know the real structure of the final spike protein(s) !

🔹 Large flexible proteins, such as a spike protein, are highly susceptible in creating mutations.

🔹 Not a single roentgen crystal structure image of spike proteins exist - neither Pfizer nor BioNTech, not even Ralph Baric and his infamous Bat Gain of function studies made any of such images. They used Cryo-EM** instead. Alone the fact that no roentgen crystal structure images exist - is a red flag !

** Cryo-EM structures - are usually blurry electron microscopic images of spike proteins, which are then are re-created into blurry 3-D models, often with added assumptions into the spike protein structure, in the data models so that they fit the exceptions :rolleyes: and bias.

🔹 Large, dynamic protein structures, such as spike protein such as a S1 subunit do not fully crystalize - so you wouldn't be able to make roentgen crystal structure images of them - which is a telling story - and a red flag reminder - that you shouldn't manipulate codons in the first place (due that those resulting large protein structures are so prone to mutations)

Well and the infamous furin cleavage site, which lead into that part of the spike protein broke away, and turned free floating in the blood, wandering into any place of the body creating damages and hyper inflammations. etc.


🔹 The Proline-lock

Prolines have a rather bad reputation in Protein Engineering, due to that they create a lot of undesired and unpredictable outcomes. What did BioNTech do ? They used not just one, but two prolines.

"A striking recurring feature of intermolecular assembly leading to both domain swapping and aggregation is proline residues. It appears that proline isomerization is the switch that triggers conversion between monomeric and oligomeric forms"

from a paper written in 2013 (!) "The how's and why's of proline folding intermediates"


In other words:
The presence of Prolines makes sure that amyloids are created !!

Dr. Sabine C. Stebel says, that "an experienced protein engineer would avoid using prolines, like devil would avoid Holy Water".
Those are telling words drawing an interesting picture, does it not ? BioNTech used two prolines in their artificial genetic code.

Protein aggregation and amyloid formation:

... In neurodegenerative diseases, the quantities of aggregates involved can sometimes be so small as to be almost undetectable, whereas in some systemic diseases literally kilograms of protein can be found in one or more organs. The characteristics of the soluble forms of the 20 or so proteins involved in the well-defined amyloidosis are very varied - they can range from intact globular proteins to largely unstructured peptide molecules - buy the aggregated forms have many characteristics in common

Reminds me of; it would explain why we found tumors-masses as large as several kilograms after only two-three of weeks in some cases of injected/boostered people.

The dangers and errors as well risk in protein engineering was out in the open in scientific world - even more than 10+ years ago. What did BioNTech do ?

Every error that was already known how and when to avoid - BioNTech did the opposite.

🧐



Different batches

🔹 Dr. Sabine C. Stebel says that the toxic PEG-nano lipids alone are sufficient to create / cause severe side effects and deaths, explaining the variations in batches.

🔹 The worse the nano lipids where done in the practical production, the better was the survival rate of the people who received the shots. :scared: bad created PEG-nano lipids couldn't transfect cells, that's why.



Stability of protein solutions / life on the edge (of solubility)

🔹 there is a very very narrow threshold present in a solution, between soluble and aggregation of proteins. If you have to many proteins in a solution - it will flock out (which of course is devastating for a person receiving a shot - creating too much protein because of the modRNA codes forces the cells into producing too high amounts).

Or in other words, if there is more protein available than what an biological organism needs, the protein is flocked out (leading to clustering, clots, illness, death). This is a very intricate, very narrow band of balance in which these things work perfectly.


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🔹 BioNTech has forced the production of proteins to high levels, without even considering the aforementioned correlation !
Things CAN go well, but only if the protein by nature is easily dissolved. Which of course, isn't always the case with proteins. If it doesn't dissolved, it is extremely dangerous for a living organism / human body. The inserted two Prolines however, destabilizes and changes the intricate balance in the protein solubility even further. The problems are multifactorial !

🔹
These things should have been tested BEFORE. Yet, the data above, is already 16 years old (!). Why haven't they been reading it ?

But hey - it has all been about operation Warp Speed, right ? :umm:



However, just wait for more bad news....


N-1-methyl-Pseudouridine !

🔹
"Pseudouridine is an unnatural nucleoside, and doesn't exist in nature". Wrong.

_-2023-10-27-at-02.08.17.jpg

🔹
The N-1-methyl-Pseudouridine is a naturally occurring modification found in 18S rRNA and tRNA in many organisms.

🔹Now though the Covid-19 injections we have brought a lot of N-1-methyl-Pseudouridine into the human cells. And let's assume that the modRNA is being broken down in the cells - then there is an awful lot of N-1-methyl-Pseudouridine left behind in the cells - which have an affinity to recycle stuff.

But where does the N-1-methyl-Pseudouridine go ? It will get installed into the Ribosomes (e.g. the apparatus in the cells, which translates and then creates proteins)

We do however not know exactly in what amounts the excessive N-1-methyl-Pseudouridine is installed, and where exactly that happens in the ribosome apparatus. But here comes another kicker:

... demonstrated that N-1-methyl-Pseudouridine increased ribosome pausing and thus change the dynamics of modified mRNA translation by increasing the recruitment or loading of ribosomes

In other words, the presence of that extra N-1-methyl-Pseudouridine left behind in cells due to the injections, increase as well changes the translation dynamics in how the cell is producing proteins !! And that's really bad news - because again - the natural pace of translation and production of proteins is highly disturbed, which leads to unknown variants of protein structures - and god knows what those then do...

The C:s said - tinkering with DNA (genetics) is at best iffy.

So true. I think that is what Dr. Sabine C. Stebel is tries to explain in her video at the Corona Investigative Committee No 165 - how many wrongs have been committed in the creation of the Covid-19 injections, showing a pretty clear picture that yes... tinkering with genetic is at best, iffy.

And at the worst it is... I would say deadly, and toxic by design. Trying to play God.


I think i leave it here

I have reached 1 hour 22 min in the video which spans 2h 13 min - otherwise it just becomes too tedious... It is already mind boggling this far. but when i first listened to it back in July 2023, i was absolutely fascinated by the sheer amount of info (and answers) the intelligent lady was giving to the people in this interview... I decided i must one day translate this (albeit first trying to wrap my head around what she was describing into english... uh).

Well, here it is - and hope i didn't make too many errors...


We know already...

In the end here at the forum, we know since a long time, that everything is wrong with the Covid-19 injections, and that the modRNA platform is by design toxic no matter what you put in there, or which single part of this dark creation you highlight... each one is bad by itself for the human body. Together it's lethal.

Dr. Sabine C. Stebel showed that those who created these toxic injections are amateurs because most of the errors were fully avoidable based on already known science being published between 2007 and 2017 - unless of course, this is all done by design combined with a deeply dark twisted sense of "having fun" to experiment on human beings, not unlike Nazi times.
 
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Correction: I wrote Mg+2 (magnesium), but meant Mn2+ (manganese)

🔹 It is possible by adding Manganese Mg2+ Mn2+ to replace the natural cofactor Mg2+ into the PCR test, which increases error prone results, due to larger amounts of mutations / false readings /reassembling of primer snippets affecting each other (mixed with the DNA from the nose scrapes, because they never cleaned and separated our own natural RNA from Virus RNA).
 
L'empire du mensonge que je dénonçais depuis le début dévoilé à l'UE. Les fameux vérificateurs des faits qui font la grève de twitter aujourd'hui, disaient que j'étais complotiste....
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The empire of lies that I denounced from the start revealed to the EU. The famous fact checkers who are on Twitter strike today said I was a conspiracy theorist....
 
Safe and effective, what do these words actually mean? Ester McVey, British MP,


in ireland


 
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Thank you for your work @XPan. I thought that nothing would shock me in case of these toxic shots, but it's mind-blowing reading what you wrote... And the general public believes that these "vaxxes" got the Nobel Prize. It reminds me of what Ed Riordan, a remote viewer, described in one of the recent sessions targeting "life extension technology", very symbolic:
(...) They don't have a real sense of reality anymore. (...) What is and what is not true doesn't matter anymore. Only the agenda. A fake narrative to bring in what they want, be it fake money or fake people. "Fake people" is interesting.

It's the time of the hanged man. Everything is upside down here.
 
Another win:

New York Supreme Court reinstates all employees fired for being unvaccinated, orders backpay

A New York state Supreme Court ordered all New York City employees who were fired for not being vaccinated to be reinstated with back pay.

The court found Monday that "being vaccinated does not prevent an individual from contracting or transmitting COVID-19." New York City Mayor Eric Adams claimed earlier this year that his administration would not rehire employees who had been fired over their vaccination status.

NYC fired roughly 1,700 employees for being unvaccinated earlier this year after the city adopted a vaccine mandate under former Mayor Bill de Blasio.
 
Quand les peuples vont comprendre, que se passera-t-il selon vous ?
+3200 % de surmortalité en Nouvelle-Zélande depuis les injections des poisons-vaccins...
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When people understand, what do you think will happen?+3200% excess mortality in New Zealand since poison-vaccine injections...
 
👍

Exclusive: He Blames COVID Protocols for His Mothers Death. Now This Filmmaker Is Using His Camera to Tell Other Victims Stories.

Clover Carroll is CEO of New Story Media, a company he co-founded to produce content for major television networks. But after his mother’s death — which Carroll blamed on COVID-19 hospital protocols — Carroll found a new calling: telling the stories of other protocol victims.

Carroll has produced the first of what he hopes will be a series of documentaries, titled “Do No Harm: The Clifton Dawley Story,” featuring the story of Clifton Dawley, whose son believes his father also died because of COVID-19 hospital protocols.
 
From zerohedge:

COVID-19 mRNA Vaccines Reduce A Major Beneficial Bacteria, Gut Biodiversity: Research

Works by gastroenterologist Dr. Sabine Hazan, the CEO of ProgenaBiome, a microbiome genomic research laboratory, found that after COVID-19 vaccination, people's Bifidobacteria levels can fall by as much as 90 percent. Some of her unpublished data found that Bifidobacteria levels are negligible in vaccinated people. Bifidobacteria are among the first microbes to colonize a baby's gastrointestinal tract as he or she passes through the mother's birth canal. They are believed to exert positive health effects on their host. Bifidobacteria interact with the immune system, and their presence is linked with improved immunity against pathogens and cancer.
 
Another one bites the dust -

PERRY-VACCINATED-1024x576.jpg


As The Gateway Pundit reported on Friday, actor Mathew Perry, best known for his role as Chandler Bing on the hit sitcom Friends, passed away at the age of 54.

TMZ reported law enforcement officers found the actor dead inside of his jacuzzi after responding to a call for cardiac arrest.

Perry, who was public about his struggles with alcohol and drug addiction, was reportedly found at his own home in a hot tub after law enforcement responded to a call for cardiac arrest around 4 pm local time.

No drugs were found at the scene.

Matthew Perry had reportedly played 2 hours of pickleball on Saturday morning and sent his assistant to run some errands. When the assistant returned to Perry’s home, he found him unresponsive and dialed 911, TMZ reported.

A prior post of Perry selling Friends-themed “Could I BE anymore vaccinated?” shirts resurfaced shortly after the news of his death became public.


:-(
 
From globalresearch [my bold]:

Graphene COVID Kill Shots: Let the Evidence Speak for Itself

I compiled all the evidence we have into this article that prove Graphene Oxide, Graphene Hydroxide and other Graphene variants are in fact being injected into people by governments and Big Pharma.

This evidence was discovered and proven numerous times already by independent research teams, scientists, Biotech whistleblowers and the few ethical Journalists remaining.

There’s a concerted effort by the pharmaceutical cartel funded “fact checkers,” Big Tech platforms and mainstream media, to hide the evidence and slander the people bringing this to light.


Once you go over the evidence provided here, you must take action for the safety of you and your families.

Serve all war criminals participating in this COVID death jab program with a Notice of Liability for the murders they are committing.

This is definitive action that any person can take, worldwide.

The notices are already drafted by legal teams so why not use them and let our enemies be on the defensive. The criminals will be reminded of the Nuremberg trials, and informed that they will be brought to justice. They need to cease and desist from acting knowingly and willfully in mandating “vaccine” death jabs and enforcing them. The evidence to the danger is clear and deaths have been proven. Anyone administering or mandating these “vaccine” kill shots are doing so without Informed Consent.

:thup:
 
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