by Peter Wisniewski
As I was driving around making sales calls today, I was amazed to hear radio talk show host, Ira Flatow, of of National Public Radio’s Science Friday speaking with Dr. Mauricio Rosas-Ballina, MD about some fascinating research about “how the immune system and brain communicate to control disease.”
His team at “The Feinstein Institute for Medical Research have identified a new anatomical path through which the brain and the spleen communicate. The spleen, once thought to be an unnecessary bit of tissue, is now regarded as an organ where important information from the nervous reaches the immune system,” according to the North Shore-Long Island Jewish Health System’s website. (1) The spleen in conventional medical science is now thought to be a reservoir for red blood cells and aids in cleaning of redundant ones.
What really is interesting is how this connection was made. The vagus nerve is the only nerve that starts in the brainstem, it supplies motor parasympathetic fibers to all organs except the adrenal glands from the neck down to the transverse colon. (2) As Dr. Rosas-Ballina followed the vagus nerve to the spleen, he found that it connected to the splenic nerve. (3) “Rosas-Ballina, MD, working with colleagues in the laboratory of Kevin J. Tracey, MD, figured out that macrophages in the spleen were making tumor necrosis factor, a powerful inflammation-producing molecule.” (1) His teams results indicate that the vagus nerve “communicates with the splenic nerve to suppress tumor necrosis factor production by macrophages in the spleen.” (1)
What this research illustrates is the inherit connection between the spleen and immune system function. What comes next for his team is developing drugs that will modulate immune response.
While this may seem like ground breaking science, Dr. Royal Lee created Spleen PMG in 1955, Dessicated Spleen in 1981, and Immuplex in 1984 which contains both the Spleen PMG and Dessicated Spleen. (4) It would seem that the health of the immune system is directly related to the health of the spleen. Luckily, three products have already been developed with no known side effects to support the spleen and immune system function.
The vascular tone of the spleen muscle wall
“The enlargement of spleen, stomach and heart because of “B” deficiency is explainable on the grounds of muscular dystrophy, known to be a specific consequence of “B” deficiency. It is that muscular weakness of the stomach walls that causes the lack of appetite in the “B” – deficiency child. The spleen has recently been demonstrated to be (before senile atrophy) a muscular organ acting as a reservoir for blood, so that a loss of muscle tone in that organ can act to cause its enlargement as well as a loss of vascular and tissue tone that is dependent upon such an “elastic” reservoir, not to speak of the loss of vascular tone due to the direct action of the deficiency on the muscular layer of the vessel walls.” (7)
Ionized calcium and nerve function
Let’s now look at nerve function support of ionized calcium in the spleen. Dr. Royal Lee said, “A study of hormones brings out similar facts. There are hormonic principles in the sex glands, spleen and suprarenal cortex, that depress the serum calcium; parathyroid hormone raises serum calcium, as also does adrenalin.” (5)
He later goes on to say, “The exception to Biost, as a source of calcium, is where alkaline calcium to form calcium bicarbonate, the ionized blood calcium, is desired. This is in the cases of acute infection (and symptoms as described above) where the calcium is to aid Vitamin C in controlling the infective agent, in the stimulation of phagocytosis. Lime water or the proprietary Kalak water are other forms of alkaline Calcium.” (9)
According to Dr. Henry Harrower M.D. “(Studies cited to show influence of spleen action simulating activity of parathyroid hormone). Removal of the spleen from dogs was followed by hypocalcemia. When a desiccated spleen extract was fed to these splenectomized dogs, the low calcium index was promptly raised to normal, although identical treatment to parathyroidectomized dogs had no such effect on the calcium figure.” (6)
JAMA said, “From the studies here discussed it appears that the spleen is likewise concerned in calcium metabolism. Furthermore, it appears that the results might even be interpreted to mean that, in the absence of the parathyroid glands, the spleen can take over their function in preventing tetany. These intricate relationships between organ systems illustrate the ends to which the organism as a whole will go in order to preserve the vital equilibrium; furthermore they indicate, in some measure, the inherent difficulties in outlining effective therapy.” (8)
In conclusion, Dr. Mauricio Rosas-Ballina, MD has shown definitive evidence that the nervous system is directly related to the spleen via the vagus nerve. We have great tools to support muscle tone of the spleen such as “B” complex. We also have tools like the Protomorphogens to control natural tissue antibodies. We have dessicated spleen to increase serum calcium. We have Calcium Lactate which converts to calcium bicarbonate in one chemical step which the body uses for nerve function of the spleen. These tools can support the spleen which in turn may support immune system function.
1) 7/21/08 Scientists Figure Out How the Immune System and Brain Communicate to Control Disease http://www.northshorelij.com/template.cfm?xyzpdqabc=0&id=204&action=detail&ref=1071
2) 7/26/08 Vagus Nerve http://en.wikipedia.org/wiki/Vagus_nerve
3) 7/25/08 Identification of Pathway that Brain and Immune System Speak http://feinsteininstitute.typepad.com/feinsteinweblog/2008/07/identification.html#comments
4) 2007 Standard Process Catalog
5) 10/15/34 Vitamin News Vol. 2 No. 9 Page 37 Dr. Royal Lee D.D.S. More on the metabolism of Calcium
6) Practical Endocrinology, Henry R. Harrower, M.D., pages 181 to 183
7) 3/15/1935 Vitamin News Vol. 3 No. 3 Page 47 Dr. Royal Lee D.D.S. Vitamin B Notes to Date
8) Quoting from the journal of the American Medical Association (Sept. 27, 1930, xcv, P. 937):
9) Therapeutic Food Manual pg 56 Dr. Royal Lee D.D.S.
Listen to the radio interview here