Indeed, something that would effect generalized depopulation is probably considered as a way to reset the chessboard. Of course, it would most likely end up wrecking the chessboard (and most of the players) but at this stage, they're probably willing to risk it. In fact, having a global economic collapse as a result of a deadly pandemic is probably seen by those types as a 'samson option'. And out of the ashes, the USA, having protected itself to some extent, would rise first and lead us all into a brave new world, much like the old one, but just worse.