Vinícius
Jedi
the receptor goes back to normal though a bit slowly, and natural OXYTOCIN is not likely to desensitize it, but the other options you quoted, things that induce a tonic release(including mdma/clonidine?) are highly likely and i'd stay awayYes, that could happen in some cases, such as after using the Pitocin to induce the labor in pregnant women.
In such cases, the repair of oxytocin receptors would probably be the proper solution.