Hi Nienna,
Nienna said:
Also, I seem to have histamine intolerance and a common theme in this is a deficiency in diamine oxidase (DAO) and mine (if this is the case) must be quite low as I react to pretty much everything. So because of this, I am assuming that my gut hasn't healed yet.
This was mentioned briefly by one of the Depression Session guests, and I have this in my notes:
JILL CARNAHAN said:
Histamine intolerance: people with MTHFR or DAO mutations can have trouble breaking down histamine; yeast and bacteria can lead to same; mast-cell destabilization: mold is a mast-cell destabilizer.
So there's two potential causes (methylation polymorphisms and infection) that aren't mutually exclusive. I did a search on 'DAO polymorphism', and this site comes up first:
http://www.deficitdao.org/
On their
DAO Deficiency tab, they have a nice summary that includes 'adverse effects derived from DAO deficiency' which you might want to compare your symptoms to. If you're looking at a DAO polymorphism, the best way to treat it would be identifying the correct methylation supplementation protocol which would allow you to bypass this particular block in your cycle and get it running smoothly again.
Yasmina Ykelenstam also has
a page on this, although you can tell she ran it through a translation program after lifting the text directly from the parent site (http://www.histaminintoleranz.ch/diagnose.html).
I've also attached a paper which may have some helpful information -- this is probably also relevant to the
Urticaria thread, since I keep seeing that come up in connection with DAO.
Hope some of this is helpful!