In November, a new coronavirus variant took the world by storm. Omicron has since caused an unprecedented wave of infections, striking about 90 million people in just 10 weeks. That’s more COVID-19 cases than were recorded in all of 2020.
Omicron also left scientists scratching their heads. It’s riddled with mutations, which might normally doom a virus. Early experiments showed that omicron wasn’t nearly as good as the previous coronavirus variant champ, delta, at melding with a cell’s membrane — crucial for infecting that cell — or at replicating in lung cells. Yet here it was, sweeping delta virtually off the map in just weeks in some places (SN: 2/10/22). Omicron even managed to infect people who already had immunity to the virus from vaccines or previous cases of COVID-19. How, researchers wondered, was omicron doing it?
“It’s a very interesting variant,” says virologist Shan-Lu Liu, who codirects the Viruses and Emerging Pathogens Program at The Ohio State University in Columbus. “I call it weird.”
Researchers in Botswana and South Africa were the first to unveil omicron’s genetic makeup. Their analysis revealed more than 60 mutations, including 42 changes alone in omicron’s spike protein — the knobby structure on the surface of the virus that initiates a cell break-in and can help evade antibody defenses. Some of those mutations have popped up in previous variants, including alpha and delta. But omicron has never-before-seen tweaks and unique combinations of mutations.
Scientists have been scrambling to discover how those changes affect omicron’s ability to infect people and cause disease. Researchers around the world are infecting cells in lab dishes with omicron mimics, putting the virus under the microscope, testing the viral variant in lab animals and examining medical and other records all to discover what makes the variant tick. Here’s what scientists have found so far.
1. Omicron keeps it together.
The secret of omicron’s increased transmissibility has proven elusive. The spike protein is certainly one key to its success, allowing omicron to infect nearly 10 times as many cells as earlier versions of the virus, researchers in China reported December 17 in Signal Transduction and Targeted Therapy.
It is “distinct from all other variants, from a structural point of view,” says structural biologist Priyamvada Acharya. She and her colleagues at the Duke Human Vaccine Institute in Durham, N.C., used cryo-electron microscopy and other techniques to examine omicron’s spike protein.
In past studies, researchers, including Acharya, have pinpointed how certain mutations have given previous variants a leg up. For instance, some mutations in the delta variant’s spike protein helped that version of the coronavirus more easily grab a human protein called ACE2 or more readily fuse with human cells (SN: 12/16/21). Omicron shares some of those mutations but has many others that drastically change how the variant behaves. “It’s not just one thing,” Acharya says. “It’s multiple properties of the spike that confer an advantage to omicron.”
Like other versions of the coronavirus, each of omicron’s knobby spikes consists of three identical pieces that snap together in a single unit. Each of those pieces has a jointed, fingerlike portion called the receptor binding domain that reaches out, much like the prongs of a claw machine, to grasp ACE2 and anchor the virus to the cell it will infect.
Many antibodies that prevent the virus from entering cells target those fingers. But omicron keeps its knuckles bent, hiding the bits that antibodies will attack, Acharya and colleagues reported in a preprint, which has not been peer reviewed yet, posted January 26 at bioRxiv.org.
Acquiring more mutations
The omicron variant of the coronavirus is more transmissible and can evade the immune system better than earlier versions of the virus, thanks in large part to mutations in spike protein. Shown here in red are locations of the mutations in the spike proteins of the delta (left) and omicron (right) variants.
S. KUMAR ET AL/JOURNAL OF MEDICAL VIROLOGY 2021
In other words, there is a significant amount of Westerners so successfully dumbed down, they no longer wish to have fights over critical thinking differences as ideologies used to — but don’t know how to and worse don’t want to critically think at all. They just want to belong.
Thus, they no longer want to govern themselves. They want to be controlled. They were made to be ruled. At this point you’re no longer intellectually persuading as we have in the past, but trying to deconstruct cult-like group think.
This is also explains their obvious contradictory positions -- as in recently nationalism and giving private citizens guns in Ukraine good but bad here -- because they're literally sheep doing/thinking/saying whatever their earthly shepherds tell them to do/say/think.
Without critically thinking, they see truth and conviction via allegiance to their overlords/hive -- not some epistemological integrity/consistency they strive for on their own.
This is also why those caught up in the Spirit of the Age instantly latch on to symbols, trademarks, etc. to indicate/prove they belong. And their positions are little more than catch-phrases. They aren't thinking, so you can't intellectually debate. They are programmed.
MOSCOW, March 2. /TASS/. Russia’s COVID-19 case tally rose by 97,455 over the past day to 16,592,824, the anti-coronavirus crisis center reported on Wednesday.
In relative terms, the growth rate reached 0.59%.
As many as 11,754 people were hospitalized with COVID-19 in Russia over the past day, down 7.8% from a day earlier. The number of hospitalized patients declined in 53 regions, while in 32 other regions the figure increased. A day earlier, 12,753 people were rushed to hospitals.
Moscow’s COVID-19 cases surged by 3,024 over the past day versus 2,066 a day earlier, reaching 2,701,834, according to the anti-coronavirus crisis center. St. Petersburg’s COVID-19 cases increased by 4,514 over the past day versus 3,421 a day earlier, reaching 1,445,730.
Patients' deaths
Russia’s COVID-19 death toll surged by 784 over the past day to 353,230.
A day earlier 786 COVID-19 deaths were registered.
The average mortality rate dropped to 2.13%, according to the crisis center.
Patients' recoveries
Russia’s COVID-19 recoveries rose by 183,530 over the past day, reaching 13,931,995.
The share of patients discharged from hospitals has risen to 83.9% of the total number of those infected.
A day earlier some 172,813 patients recovered.
The number of patients undergoing outpatient treatment rose to 2,307,599.
Steve Kirsch: Germ Line Mutation Allegations Easy to TestThis is an open letter to Steve Kirsch that is a result of discussions between me and Andreas Oehler and some of our substack contributors.
Steve, in light of the recent discussions of mRNA vaccines reverse transcribing into DNA, our readers pointed us at an unsigned and anonymous 4chan post from the year of 2020 (!) making several allegations. It is shown below:
The short of this (and you need to read the above image) is that this post alleged that mRNA vaccine, from Moderna specifically but also allegedly Pfizer, is designed for, and has secret ingredients, to modify the “germ line”, that is, female eggs and sperm, such that children born to vaccinated parents have certain genetic damage (see below).
Ordinarily, such anonymous and unsourced allegations would not deserve any attention, except
Several hard-to-make-up allegations from the post have been already verified by Andreas Oehler and me.
- This was actually well written using proper trade jargon
- This was written in 2020 BEFORE anything became known about dangers of mRNA vaccines and the terms used were not on the radar
- Many allegations of this post actually check out. Specifically, LINE-1 reverse transcriptase interacts with vaccines, and DNA reverse transcription does convert mRNA into DNA in human cells, and Pfizer’s whistleblower specifically mentioned mysterious “manual steps” (per Andreas post above).
- This stuff is very hard to make up without knowing
- This somewhat explains otherwise-irrational and maniacal drive to vaccinate as many young people as possible regardless of their convalescent status or need/benefits
about the 2nd stepI hope that the whole thing below is just trolling made by someone, but as events are unfolding, I wouldn't be surprised if it's true:
Steve Kirsch: Germ Line Mutation Allegations Easy to Test
about the 2nd step
CYP19A
mutation of CYP19A from CYP19A1 cytochrome P450 family 19 subfamily A member 1 [Homo sapiens (human)] - Gene - NCBI
Official Symbol CYP19A1provided by HGNC
Official Full Name cytochrome P450 family 19 subfamily A member 1provided by HGNC
Primary source HGNC:HGNC:2594
See related Ensembl:ENSG00000137869 MIM:107910; AllianceGenome:HGNC:2594
Gene type protein coding
RefSeq status REVIEWED
Organism Homo sapiens
Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]
Expression Restricted expression toward placenta (RPKM 83.2) See more
and from Wikipedia
Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens. It is CYP19A1, a member of the cytochrome P450 superfamily (EC 1.14.14.1), which are monooxygenases that catalyze many reactions involved in steroidogenesis. In particular, aromatase is responsible for the aromatization of androgens into estrogens. The enzyme aromatase can be found in many tissues including gonads (granulosa cells), brain, adipose tissue, placenta, blood vessels, skin, and bone, as well as in tissue of endometriosis, uterine fibroids, breast cancer, and endometrial cancer.[citation needed] It is an important factor in sexual development.
CDKN1B
and from Wikipedia for CDKN1B
Cyclin-dependent kinase inhibitor 1B (p27Kip1) is an enzyme inhibitor that in humans is encoded by the CDKN1B gene.[5] It encodes a protein which belongs to the Cip/Kip family of cyclin dependent kinase (Cdk) inhibitor proteins. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. It is often referred to as a cell cycle inhibitor protein because its major function is to stop or slow down the cell division cycle.
If the above info on the makeup of the vaccines is true, then it does not look good for future generations.
The paper presents the effect of COVID-19 mRNA (Pfizer/BioNT) vaccine on in vitro glial cells of the brain studied by means of Raman spectroscopy and imaging. The results obtained for human brain normal and tumor glial cells of astrocytes, astrocytoma, glioblastoma incubated with the Covid-19 mRNA vaccine Pfizer/BioNT vaccine show alterations in the reduction-oxidation pathways associated with Cytochrome c. We found that the Pfizer/BioNT vaccine down regulate the concentration of cytochrome c in mitochondria upon incubation with normal and tumorous glial cells. Concentration of oxidized form of cytochrome c in brain cells has been shown to decrease upon incubation the mRNA vaccine. Lower concentration of oxidized cytochrome c results in lower effectiveness of oxidative phosphorylation (respiration), reduced apoptosis and lessened ATP production. Alteration of Amide I concentration, which may reflect the decrease of mRNA adenine nucleotide translocator. Moreover, mRNA vaccine leads to alterations in biochemical composition of lipids that suggest the increasing role of signaling. mRNA vaccine produce statistically significant changes in cell nucleus due to histone alterations. The results obtained for mitochondria, lipid droplets, cytoplasm may suggest that COVID-19 mRNA (Pfizer/BioNT) vaccine reprograms immune responses. The observed alterations in biochemical profiles upon incubation with COVID-19 mRNA in the specific organelles of the glial cells are similar to those we observe for brain cancer vs grade of aggressiveness.
Professor Halina Abramczyk (Chemical Sciences, FWCI: 1.96; h-index: 23; publications in Top 10 Citation percentile: 33.3%). She conducts research on diagnostic methods to detect early cancerous changes by Raman microscopy, Raman molecular imaging and femtosecond laser spectroscopy.
She is the founder and director of the Laboratory of Laser Molecular Spectroscopy at TUL. She was professor and head of the Marie Curie Chair in Berlin at the Max Born Institute in 2007-2009. She organized the European Virtual University on Lasers.
She was a visiting professor at the Consejo Superior de Investigaciones Cientificas, Madrid, Spain (1989), Martin Luther University of Halle-Wittenberg, Germany (1992), the University of Arizona, Tucson, USA (2002-2003), Max Born Institute, Berlin, Germany (2007-2009), the University of Nairobi, Kenya (2009-2010).
She is a member of the Editorial Board of the Journal of Molecular Liquids and a board member of the European Molecular Liquids Group.
She has delivered numerous keynote and invited lectures in Poland and abroad.
She received a Fulbright Award and has been President of the Polish Fulbright Alumni Association since 2013.
She has published extensively in the field of molecular spectroscopy, laser spectroscopy and biomedical diagnostics. She is the author of the book “Introduction to Laser Spectroscopy” (Elsevier, 2005) and its Polish edition (PWN, 2000).
Remember how Fulcanelli and the other master alchemists absolutely loved to play games with words? Especially how their favorite was wordplay via phonetics?I’ve said it before but I say it again: based on what I’ve listened to and seen featuring in his show I don’t consider Stew Peters to be one last bit reliable. He tries to present ‘bombshells’ and ‘secrets’ on every show with little or no evidence to support them. I don’t know if he’s controlled opposition or just a fortune seeker. In any case, I’d recommend that you take everything that goes on in that show with a huge grain of salt.
Yes it says it! Read :The article doesnt say anything about the vaccination status of the parents. If the mother would be vaccinated that could explain it.
The image below is of a blood sample from a vaccine-free, or unvaccinated, three-year-old child. It shows pieces or “shards” of graphene that “are the result of shedding.” In other words the graphene has been transmitted from “vaccinated” parents to their unvaccinated child.
No, graphene doesn't self-replicate. It can serve as matrix for assembling other molecules, it can be divided in numerous bits of graphene, but it doesn't replicate in blood. It's not a living molecule. It is even slowly degraded in the body for being excreted from the body, thus the need to re-jab people again and again. Spike Protein can be produced in lots of copies, and all along life, because there is the mRNA integrated inside the cells, thus being able to order its production via aminoacids.Nanotech can be self-replicating but AFAIK needs graphene oxyd, as example, as base for this. Rumour is that large parts of the food chain is poisend with GO.