Intravenous nutrient therapy: the "Myers' cocktail". - PubMed - NCBI [Click on "Full text links" for more info. Very interesting cases available!]
Here're more excerpts of this article written by Dr. Alan R. Gaby in 2002.
"The modified “Myers’ cocktail,” which consists of magnesium, calcium, B vitamins, and vitamin C, has been found to be effective against acute
asthma attacks, migraines, fatigue (including chronic fatigue syndrome), fibromyalgia, acute muscle spasm, upper respiratory tract infections, chronic sinusitis, seasonal allergic rhinitis, cardiovascular disease, and other disorders."
"Over an 11-year period, approximately 15,000
injections were administered in an outpatient setting
to an estimated 800-1,000 different patients.
Conditions that frequently responded included
asthma attacks, acute migraines, fatigue (including
chronic fatigue syndrome), fibromyalgia, acute
muscle spasm, upper respiratory tract infections,
chronic sinusitis, and seasonal allergic rhinitis. A
small number of patients with congestive heart
failure, angina, chronic urticaria, hyperthyroidism,
dysmenorrhea, or other conditions were also
treated with the Myers’ and most showed marked
improvement. Many relatively healthy patients
chose to receive periodic injections because
it enhanced
their overall well being for periods of a
week to several months."
"
The Modified Myers’ Cocktail
Dexpanthenol is the commercially available
injectable form of pantothenic acid (vitamin
B5). One milliliter of B complex 100 contains 100
mg each of thiamine and niacinamide, and 2 mg
each of riboflavin, dexpanthenol, and pyridoxine.
All ingredients are drawn into one syringe,
and 8-20 mL of sterile water (occasionally more)
is added to reduce the hypertonicity of the solution.
After gently mixing by turning the syringe a
few times, the solution is administered slowly,
usually over a period of 5-15 minutes (depending
on the doses of minerals used and on individual
tolerance), through a 25G butterfly needle. Occasionally,
smaller or larger doses than those listed
in Table 1 have been used. Low doses are often
given to elderly or frail patients, and to those with
hypotension. Doses for children are lower than
those listed, and are reduced roughly in proportion
to body weight. The most commonly used
regimen has been 4 mL magnesium, 2 mL calcium,
1 mL each of B12, B6, B5, and B complex,
6 mL vitamin C, and 8 mL sterile water."
"
Asthma
Case #1: A five-year-old boy presented
with a two-year history of asthma. During the previous
12 months he had suffered 20 asthma attacks
severe enough to require a visit to the hospital
emergency department. His symptoms appeared
to be exacerbated by several foods, and
skin tests had been positive for 23 of 26 inhalants
tested. His initial treatment consisted of identification
and avoidance of allergenic foods, as well
as daily oral supplementation with pyridoxine (50
mg), vitamin C (1,000 mg), calcium (200 mg),
magnesium (100 mg), and pantothenic acid (100
mg), in two divided doses with meals. On this regimen,
he experienced marked improvement, and
had no asthma attacks requiring medical care until
nearly 11 months after his initial visit.
At that time the child, now six years old,
presented for an emergency visit with mild but
persistent wheezing and difficulty breathing. He
was given a slow IV infusion containing 6 mL
vitamin C, 1.4 mL magnesium, and 0.5 mL each
of calcium, B12, B6, B5, and B complex. The
symptoms resolved within two minutes and did
not recur.
Over the ensuing eight years and three
months, he received a total of 63 IV treatments
for acute exacerbations of asthma. In most instances,
a single injection resulted in marked improvement
or complete relief within two minutes,
and the acute symptoms did not recur."
"Migraine
Case #2: A 44-year-old female suffered
from frequent migraines, which appeared to be
triggered in many instances by exposure to
environmental chemicals or, occasionally, to
ingestion of foods to which she was allergic.
Allergy desensitization therapy had provided little
benefit. Over a six-year period, the patient was
given IV therapy on approximately 70 occasions
for migraines. Nearly all of these injections
resulted in considerable improvement or complete
relief within several minutes, although a few
treatments were ineffective. Through trial and
error, it was determined her most effective regimen
was 16 mL vitamin C, 5 mL magnesium, 4 mL
calcium, 2 mL B6, and 1 mL each of B12, B5, and
B complex. The 4-mL dose of calcium was found
to provide better relief than lower calcium doses.
Over the years, a half dozen other patients
have presented one or more times with an acute
migraine. In almost every instance, the Myers’
produced a gratifying response within a few minutes."
"
Fatigue
Many patients with unexplained fatigue
have responded to the Myers’, with results lasting
only a few days or as long as several months. Patients
who benefited often returned at their own
discretion for another treatment when the effect
had worn off. One patient with fatigue associated
with chronic hepatitis B experienced marked and
progressive improvement in energy levels with
weekly or twice-monthly injections.
Approximately 10 patients with chronic
fatigue syndrome (CFS) received a minimum of
four treatments (usually once weekly for four
weeks), with more than half showing clear improvement.
One patient experienced dramatic benefit
after the first injection, whereas in other cases
three or four injections were given before improvement
was evident. A few patients became progressively
healthier with continued injections and were
eventually able to stop treatment. Several others
did not overcome their illness, but periodic injections
helped them function better."
"Fibromyalgia
Case #3: A 48-year-old woman presented
with a six-year history of fairly constant myalgias
and arthralgias, with pain in the neck, back, and
hip, and tightness in the left arm. Six months previously
she was found to have an elevated sedimentation
rate (50 mm/hr). She was diagnosed by
a rheumatologist as possibly having polymyalgia
rheumatica, although the diagnosis of fibromyalgia
was also considered. Her history was also significant
for migraines about eight times per year and
chronic nasal congestion. Physical examination
revealed extremely stiff muscles, with decreased
range of motion in many areas of her body.
The patient was given a therapeutic trial
consisting of 6 mL vitamin C, 4 mL magnesium,
2.5 mL calcium, and 1 mL each of B12, B6, B5,
and B complex. At the end of the injection, she
got off the table and, with a look of amazement,
announced her muscle aches and joint pains were
gone for the first time in six years. This treatment
was repeated after a week (at which time her symptoms
had not returned), followed by every other
week for several months, then once monthly for
three years. Her initial regimen also included the
identification and avoidance of allergenic foods
and treatment with low-dose desiccated thyroid
(eventually stabilized at 60 mg per day). She discovered
that eating refined sugar caused myalgias
and arthralgias, and that thyroid hormone improved
her energy level, mood, and overall well
being. During the three years of monthly maintenance
injections she reported symptoms would
begin to recur if she went much longer than a
month between treatments. However, they were
never as severe as they were before she began receiving
IV therapy.
The author has given the Myers’ to approximately
30 patients with fibromyalgia; half
have experienced significant improvement, in a
few cases after the first injection, but more often
after three or four treatments."
"
Depression
Case #4: A 46-year-old man presented
with a history of depression and anxiety since
childhood. He had been in psychoanalysis for the
past eight years. A therapeutic trial with IV nutrients
was considered because the patient reported
that consumption of alcohol (known to deplete
magnesium) aggravated his symptoms, and because
he was taking a magnesium-depleting thiazide
diuretic for hypertension. He was initially
given 1 mL each of magnesium, B12, B6, B5, and
B complex, which resulted in a 70-80 percent reduction
in his symptoms for one week. A second
injection produced a similar response that lasted
two weeks. Through trial and error it was determined
the most effective treatment was 5 mL
magnesium, 3 mL B complex, and 1 mL each of
B12, B6, and B5.
The addition of calcium to the
injection appeared to block some of the benefit.
Both oral and IM administration of the same nutrients
were tried but found to be ineffective.
Weekly injections provided almost complete relief
from symptoms and allowed him to discontinue
psychotherapy. The patient noted that
rapidly
administered injections provided longer-lasting
relief than did slower injections. The infusion
rate was therefore carefully and progressively increased,
without causing any adverse side effects
or changes in blood pressure or heart rate. The
patient reported that when the treatment was given
over a one-minute period, the effect would last
approximately two weeks, whereas a slower injection
(such as five minutes) would last only a
week. Approximately four years after initial treatment,
he was able to reduce the frequency of injections
to once monthly or less.
Many other patients with depression and/
or anxiety have shown a positive response to the
Myers’. However, this treatment should not be
considered first-line therapy for major depression.
It seems to be helpful only for certain subsets of
depressed individuals, such as those who also suffer
from fibromyalgia, migraines, excessive stress,
or alcohol-induced exacerbations. Shealy et al
have observed an antidepressant effect of IV magnesium
in some patients with chronic pain.39"
"Cardiovascular Disease
Case #5: A 79-year-old man was seen at
home in end-stage heart failure, after having suffered
four myocardial infarctions. During the previous
12 months, spent mostly in the hospital, he
had become progressively worse;
his ejection fraction
had fallen to 19 percent and his body weight
had declined from 171 pounds to a severely
cachectic 113 pounds. He was confined to bed and
required supplemental oxygen much of the time.
He also had severe peripheral occlusive arterial
disease, which had resulted in the development of
gangrene of six toes. A peripheral angiogram revealed
complete occlusion of both femoralpopliteal
arteries, with no detectable blood flow
to the distal extremities.
Two independent vascular
surgeons had recommended bilateral above the-
knee amputations to prevent development of
septicemia. However, the cardiologist advised the
patient that his heart would not last more than
another month, so the patient declined the amputations.
He was treated with weekly IM injections
of magnesium sulfate (1 g) for eight weeks, and
prescribed oral supplementation with vitamins C
and E, B complex, folic acid, and zinc. T
he magnesium
injections appeared to reduce the pain in
his gangrenous toes considerably, with the benefit
lasting about five days each time. Six weeks
after the first injection, his ejection fraction had
increased from 19 percent to 36 percent and he no
longer required supplemental oxygen. After eight
weeks, the IM injections were replaced by weekly
IV injections, consisting of 5 mL magnesium, 1
mL each of B12, B6, B5, and B complex, and a
low-dose (0.2 mL) trace mineral preparation
(MTE-5 containing: zinc, copper, chromium, selenium,
and manganese).
After a total of 18
months, his weight had increased from 113 to 147
pounds, which was remarkable as cardiac cachexia
is generally considered to be irreversible. In addition,
the gangrenous areas on his toes had sloughed
and been replaced almost entirely by healthy tissue.
Intravenous therapy was continued and eventually
reduced to every other week. The patient
lived for eight years and died at age 87 from multiple
organ failure.
Of the handful of other patients with angina
or heart failure who received IV or IM injections
of magnesium (with or without B vitamins),
all showed significant improvement. The results
with angina are consistent with those reported by
others using parenteral magnesium therapy."
"Upper Respiratory Tract Infections
Case #6: A 40-year-old male presented
with a cold and a one-day history of fatigue, nasal
congestion, and rhinorrhea. He was given an IV
infusion of 16 mL vitamin C, 3 mL magnesium,
1.5 mL calcium, and 1 mL each of B12, B6, B5,
and B complex. By the end of the 10-minute treatment
he was symptom free. The cold symptoms
did return the next day but were only 10 percent
as severe as before the injection.
One-quarter to one-third of patients who
received the Myers’ for an acute respiratory infection
experienced marked improvement, either
immediately or by the next morning. Approximately
half of patients given this treatment reported
that it shortened the duration of their illness.
Patients who benefited tended to have a similar
response if treated for a subsequent infection,
whereas non-responders tended to remain non-responders.
Case #7: A 32-year-old female had a long
history of chronic sinusitis. Avoidance of allergenic
foods and oral supplementation with vitamin
C and other nutrients had provided only minimal
benefit. She was given an IV infusion of 20
mL vitamin C, 4 mL magnesium, 2 mL calcium,
and 1 mL each of B12, B6, B5, and B complex;
this protocol was repeated the next day. At the time
these injections were given she had been experiencing
persistent sinus problems for a year. Her
symptoms resolved rapidly after the injections and
she remained relatively symptom free for more
than six months. The same treatment given at a
later date was also helpful, although the benefit
was not as pronounced as the first time.
One other patient with chronic sinusitis
had a similar response to back-to-back injections,
while a few others showed no improvement."
"Seasonal Allergic Rhinitis
Case #8: A 38-year-old man had a long
history of seasonal allergic rhinitis, occurring each
spring and lasting about a month. Symptoms included
nasal congestion, itchy eyes, and fatigue.
During a symptomatic period, an IV infusion of
12 mL vitamin C, 3 mL magnesium, and 1 mL
each of B12, B6, B5, and B complex provided
rapid relief. This treatment was repeated as needed
during the hay fever season (once weekly or less)
and successfully controlled his symptoms. In subsequent
years he began the IVs shortly before, and
repeated them periodically during, the hay fever
season;
this approach prevented the development
of symptoms."
"Narcotic Withdrawal
Case #9: A 35-year-old man addicted to
morphine came to the office in the early stages of
withdrawal, with diaphoresis and extreme agitation.
He was given an IV infusion of 16 mL vitamin
C, 5 mL magnesium, 2.5 mL calcium, and 1
mL each of B12, B6, B5, and B complex. In his
agitated state he was unable to sit still on the exam
table, so we walked up and down the hall with a
butterfly needle in his arm.
Halfway through the
injection, he was able to sit still, and by the end of
the injection his withdrawal symptoms were alleviated.
The symptoms returned 36 hours later; he
therefore came for another treatment, which again
relieved the symptoms within minutes. He returned
the next day, still symptom free, for a third
injection, which carried him uneventfully through
the remainder of the withdrawal period."
"
Chronic Urticaria
Case #10: A 71-year-old woman had
chronic urticaria with hives present somewhere
on her body nearly every day for 10 years. An allergy-
elimination diet and oral supplementation
with vitamin C and other nutrients provided little
or no relief. She was given an IV infusion of 12
mL vitamin C, 3 mL magnesium, 1.5 mL calcium,
and 1 mL each of B12, B6, B5, and B complex.
The same treatment was repeated the following
day. After these injections the hives resolved rapidly
and did not recur for more than a year. When
the lesions did recur, the IV treatment was repeated
but was ineffective."
"
Hyperthyroidism
Two patients with hyperthyroidism were
treated with the Myers’ once or twice weekly for
several weeks. In one case, the treatment controlled
the symptoms of hyperthyroidism, although
there was no reduction in thyroid-hormone levels.
The injections were discontinued after medical
therapy had restored the hormone levels to
normal. In the other case, symptoms improved
markedly after the first injection and thyroid-function
tests, measured two weeks later, returned to
normal.
The potential value of IV nutrient therapy
for patients with hyperthyroidism is supported by
several studies. Serum and erythrocyte magnesium
levels have been found to be low in patients with
Graves’ disease.43 In addition,
daily IM injections
of magnesium chloride (20 mL of a 14-percent
solution) for 3-7 weeks reduced the size of the
thyroid gland and improved the clinical condition
of three patients with hyperthyroidism.44 Intravenous
vitamin B6 (50 mg per day) was reported to
relieve muscle weakness in three patients with
hyperthyroidism,45 and animal studies indicate
vitamin B12 can counteract some of the adverse
effects of experimentally induced hyperthyroidism."