There seems to be a lot of competing interests in the race to come up with a vaccine. It's interesting that Trump is involved since he started out as an
anti-vaxxer. Could be he's getting pressured or backed into a corner over the vaccine issue, but I wonder if he is trying to get a harmless vaccine out or if that's what the C's are referring to when they mention that the plans will backfire?
Amended: 2015 patent application entry to add that Pirbright Institute names WHO and Bill and Melinda Gates Foundation as stakeholders.
Added:
- MARCH 2016
Gates Foundation bets big on Moderna’s mRNA technology
"The announcement of the Gates Foundation grant comes just weeks after Moderna revealed two new partnerships focused on leveraging its mRNA platform.
Merck will license a vaccine program from Moderna to be used against an undisclosed viral target, and AstraZeneca entered a collaboration with Moderna to discover, co- develop and co-commercialize mRNA therapeutic candidates for the treatment of a range of cancers. Both agreements build on ongoing collaborations with the two pharmaceutical companies.
- MARCH 27, 2020
Italian scientists investigate possible earlier emergence of coronavirus
Adriano Decarli, an epidemiologist and medical statistics professor at the University of Milan, said there had been a “significant” increase in the number of people hospitalized for pneumonia and flu in the areas of Milan and Lodi between October and December last year.
He told Reuters he could not give exact figures but “hundreds” more people than usual had been taken to hospital in the last three months of 2019 in those areas - two of Lombardy’s worst hit cities - with pneumonia and flu-like symptoms, and some of those had died.
- MARCH 30, 2020
The U.S. Just Signed A $450 Million Coronavirus Vaccine Contract With Johnson & Johnson
The Trump administration is spending nearly half a billion dollars on one company in the race to find a coronavirus vaccine.
That’s according to a $456 million order with Johnson & Johnson’s Pharmaceuticals arm Janssen, which specified a “new vaccine asset for 2019 Novel Coronavirus (COVID-19),” Forbes found. It’s the largest reported amount spent on a vaccine project to date, even though the pharma giant hasn’t yet started any clinical trials as other firms have.
The deal was signed with the Health and Human Services Office of the Assistant Secretary for Preparedness and Response (ASPR) on March 27, 2020. It followed another order, made as part of the same contract with Janssen, for $150 million on March 20, 2020, for a “new antiviral” for COVID-19.
A spokesperson from Johnson & Johnson didn’t provide any more details on the specific order, but confirmed the $456 million award related to a collaboration with ASPR’s Biomedical Advanced Research and Development Authority (BARDA), as
announced in February. That work was built on previous contracts for developing countermeasures for other influenzas. The value of the coronavirus-specific work hadn’t previously been revealed and is the largest known contract for a coronavirus vaccine to date.
Corona Virus timeline
CHINA Nov, 2002: After its experience with the SARS outbreak in Guangdong Province in 2002, China implemented a rapid response protocol for infectious diseases. The protocol empowered the Health Ministry to assemble professional and managerial help from across the country, established an emergency response coordinating team, prepared funding and authorization for supplies, equipment and emergency health care facilities, anticipating that existing hospitals would be overwhelmed.
USA April, 2004: Patent Application
USA Nov, 2006: Patent SARS coronavirus. Abstract: An outbreak of a virulent respiratory virus, now known as Severe Acute Respiratory Syndrome (SARS), was identified in Hong Kong, China and a growing number of countries around the world in 2003. The invention relates to nucleic acids and proteins from the SARS coronavirus. These nucleic acids and proteins can be used in the preparation and manufacture of vaccine formulations, diagnostic reagents, kits, etc. The invention also provides methods for treating SARS by administering small molecule antiviral compounds, as well as methods of identifying potent small molecules for the treatment of SARS.
USA Sep 2008: Though the first cases of H1N1 swine flu were reported in California and Texas in late March, 2009, subsequent genetic analysis suggests that it began six months before it was first detected, in
September, 2008, at the start of the ‘flu season. The CDC admits, below, that earlier Covid-19 cases went undetected, too
USA & NETHERLANDS Dec 2011 Researchers studying a potentially more lethal, airborne version of bird flu have suspended their studies
because of concerns the mutant virus they have created could be used as a devastating form of bioterrorism or accidentally escape the lab.
TWO YEAR GAP
UK, Saudi Arabia, Jordan Feb/Mar 2013 New Mystery Virus kills 9th Victim, This virus is in the family of coronaviruses, a new virus, previously unknown to mankind, Symptoms of the disease consist of respiratory distress, fever, coughing and difficulty in breathing.
USA Jul, 2015: Patent application lodged for attenuated coronavirus by
The Pirbright Institute (UK), application granted November 2018. Pirbright Institute names WHO and the Bill and Melinda Gates Foundation as stakeholders.
USA March, 2016: Gates Foundation bets big on Moderna’s mRNA technology
"The announcement of the Gates Foundation grant comes just weeks after Moderna revealed two new partnerships focused on leveraging its mRNA platform.
Merck will license a vaccine program from Moderna to be used against an undisclosed viral target, and AstraZeneca entered a collaboration with Moderna to discover, co- develop and co-commercialize mRNA therapeutic candidates for the treatment of a range of cancers. Both agreements build on ongoing collaborations with the two pharmaceutical companies.
USA Jun, 2017: World Bank issues
Pandemic Bonds for emergency pandemic financing and pandemic insurance.
USA May, 2018: The President
Fires the entire US Pandemic Response Team and does not replace it.
USA Nov 2018: Patent application for attenuated coronavirus (see July 2015) granted.
USA Apr, 2019: An
outbreak of severe
vaping-associated lung illness is exclusively confined to the United States, despite the fact that the majority of vapers live outside the US.
USA Jul 3, 2019: The CDC
halts research at Fort Detrick, citing “national security reasons” for not releasing information about its decision.
USA Jul 14, 2019: Chinese researcher
escorted from infectious disease lab amid RCMP investigation. Public Health Agency of Canada describes it as a possible ‘policy breach,’ no risk to Canadian public. The first Chinese to discover or warn about the Covid-19 outbreak?
AUSTRALIA Aug, 2019: Australia Health Management Plan for Pandemic Influenza released.
USA Aug, 2019: First Vaping Death Reported by Health Officials “Amid the lack of
information, investigators scrambled to find shared links to the respiratory problems. Officials said earlier this week that many patients, most of whom were adolescents or young adults, had described difficulty breathing, chest pain, vomiting and fatigue,” the precise symptoms of Covid-19 infection.
USA Sep 2019: Recently (2020), a team of Chinese researchers claimed to demonstrate that Covid-19 was born in September, 2019. The British researchers who had discovered the earlier H1N1 date
are not convinced.
ITALY Oct - Dec, 2019: Adriano Decarli, an epidemiologist and medical statistics professor at the University of Milan, said there had been a “significant” increase in the number of people hospitalized for pneumonia and flu in the areas of Milan and Lodi between October and December (See entry March 27, 2020)
USA Oct 18, 2019: The Johns Hopkins Center for Health Security in partnership with the World Economic Forum and the Bill and Melinda Gates Foundation hosted
Event 201, a high-level pandemic exercise on October 18, 2019, in New York, NY. Event 201 simulated an "outbreak of a novel zoonotic coronavirus transmitted from bats to pigs to people that eventually becomes efficiently transmissible from person to person, leading to a severe pandemic that leaves 65 million dead.
CHINA Oct 27, 2019 At a peak of international tension and the ‘flu season in the northern hemisphere, on the eve of China’s biggest travel season, 300 American military servicemen visit Wuhan for the International Military Games.
USA Dec, 2019. A Chinese medical researcher is arrested in Boston trying to take biological samples back to China. Zheng Zaosong, of Beth Israel Deaconess Medical Center, confessed to taking material from a lab in Boston. FBI Special Agent Kara Spice found 21 wrapped vials containing a “brown liquid” that appeared to be “biological material” (samples of post-mortem lung tissue look like ‘brown liquid’). Zheng’s roommate, also a researcher, told FBI agents that two labmates of Zheng had succeeded in getting specimens to China. China, presumably, now went on high alert.
USA/CHINA Dec 2019: Chinese researchers in the USA informed China’s Health Ministry of a novel Coronavirus outbreak there, triggering a readiness alert nationwide. The WHO describes what happened next, “In the face of a previously unknown virus, China has rolled out perhaps the most ambitious, agile, and aggressive disease containment effort in history…China’s bold approach to contain the rapid spread of this new respiratory pathogen has changed the course of a rapidly escalating and deadly epidemic.”
CHINA Dec 26, 2019: Jixian Zhang detects four anomalous pneumonia infections in Wuhan and reports them to the provincial CDC the next day. The provincial authorities immediately inform the national CDC which prepares to implement the pandemic response protocols.
GERMANY Dec 25-Dec 31, 2019: Charité (clinic in Berlin)
starts developing test for the new Corona virus after first informal information reaches them. Later sends prototype to China, "unnamed colleagues" in China confirm that it works. WHO then publishes the test on its website as the first test. China develops own test, but demand is high elsewhere - even in Southeast Asia.
CHINA Dec 30, 2019: China’s national CDC notifies the WHO
CHINA Dec 31, 2019: WHO reports Zhang’s discovery to the world.
MALAYSIA Jan 5, 2020: Malaysia’s Assistant to the Prime Minister, Matthias Chang, speculates that the US is waging biological warfare on China.
USA Jan 6: Infectious disease expert Amesh A. Adalja, M.D., senior scholar at the Johns Hopkins Center for Health Security, agrees, “We are on track to have a season like the 2017-2018 season,” when 80,000 Americans died of flu complications. The Centers for Disease Control and Prevention (CDC) issued a travel notice for Wuhan, China due to the spreading coronavirus
CHINA January 7: China identifies the virus as 2019-nCov and confirms it five days later.
President Xi tells officials that the country is on a ‘war footing’
USA Jan 7: The CDC established a coronavirus incident management system to better share and respond to information about the virus
USA Jan 11: The CDC issued a Level I travel health notice for Wuhan, China
CHINA Jan 13: China makes the first 2019-nCov test kits available.
USA Jan 17: The CDC began implementing public health entry screening at the 3 U.S. airports that received the most travelers from Wuhan – San Francisco, New York JFK, and Los Angeles
USA Jan 19: A 35-year-old man presented to an urgent care clinic in Snohomish County, Washington, with a 4-day history of cough and subjective fever. He disclosed that he had returned to Washington State on January 15 after traveling to visit family in Wuhan, China. Apart from a history of hypertriglyceridemia, the patient was an otherwise healthy nonsmoker. On January 20, 2020, the CDC confirmed that the patient’s nasopharyngeal and oropharyngeal swabs tested positive for 2019-nCoV. By Jan. 30, the patient’s symptoms had resolved, according to a New England Journal of Medicine paper. Snohomish County officials allowed him to leave home isolation three weeks later.
USA Jan 20: Dr Fauci announces the National Institutes of Health is already working on the development of a vaccine for the coronavirus
USA Jan 21: The CDC activated its emergency operations center to provide ongoing support to the coronavirus response
USA Jan 23: The CDC sought a “special emergency authorization” from the FDA to allow states to use its newly developed coronavirus test
CHINA Jan 25: Construction begins on a 1,000 bed intensive care hospital in Wuhan.
CHINA Jan 26: China extends Spring Festival holiday to contain the outbreak.
USA Jan 27: The CDC issued a level III travel health notice urging Americans to avoid all nonessential travel to China due to the coronavirus
USA Jan 28: Harvard Chemistry Professor Arrested, Handcuffed, And Accused Of Lying About Ties To China. Charles Lieber, Chair of Harvard’s Department of Chemical Biology, led a Chinese research group focusing on the use of nanotechnology to identify viruses.
USA Jan 29: The White House announced the formation of the Coronavirus Task Force to help monitor and contain the spread of the virus and provide updates to the President
USA Jan 31: The Trump Administration:Declared the coronavirus a public health emergency; Announced Chinese travel restrictions; Suspended entry into the United States for foreign nationals who pose a risk of transmitting the coronavirus. The Department of Homeland Security took critical steps to funnel all flights from China into just 7 domestic U.S. airports
USA Feb 3: The CDC had a team ready to travel to China to obtain critical information on the novel coronavirus, but were in the U.S. awaiting permission to enter by the Chinese government
USA Feb 4: President Trump vowed in his State of the Union Address to “take all necessary steps” to protect Americans from the coronavirus
CHINA Feb 5: First patients moved into new 1,000 bed intensive care hospital.
USA Feb 6: The CDC began shipping CDC-Developed test kits for the 2019 Novel Coronavirus to U.S. and international labs
USA Feb 9: The White House Coronavirus Task Force briefed governors from across the nation at the National Governors’ Association Meeting in Washington
USA Feb 11: The Department of Health and Human Services (HHS) expanded a partnership with Janssen Research & Development to “expedite the development” of a coronavirus vaccine
USA Feb 12: The U.S. shipped test kits for the 2019 novel coronavirus to approximately 30 countries who lacked the necessary reagents and other materials; The CDC was prepared to travel to China but had yet to receive permission from the Chinese government
USA Feb 14: The CDC began working with five labs to conduct “community-based influenza surveillance” to study and detect the spread of coronavirus
USA Feb 18: HHS announced it would engage with Sanofi Pasteur in an effort to quickly develop a coronavirus vaccine and to develop treatment for coronavirus infections
CHINA Feb 23. Chinese scientists
found genomic evidence that the seafood market in
Wuhan was not the source of the novel coronavirus. Their genetic data suggests the virus was introduced from elsewhere and had already circulated widely among humans in Wuhan before December 2019, probably beginning in mid- to late November.
USA Feb 24: The Trump Administration sent a letter to Congress requesting at least $2.5 billion to help combat the spread of the coronavirus
USA Feb 26: President Trump discussed coronavirus containment efforts with Indian PM Modi and updated the press on his Administration’s containment efforts in the U.S. during his state visit to India
CHINA Feb 27: On
Taiwan TV a prominent virologist explained flow charts suggesting that the coronavirus originated in the US.
USA Feb 29: The Food and Drug Administration (FDA) allowed certified labs to develop and begin testing coronavirus testing kits while reviewing pending applications. The Trump Administration:Announced a level 4 travel advisory to areas of Italy and South Korea; Barred all travel to Iran; Barred the entry of foreign citizens who visited Iran in the last 14 days
USA Mar 3: The
Director General of the WHO announced: "While many people globally have built up immunity to seasonal flu strains, COVID-19 is a new virus to which no one has immunity. That means more people are susceptible to infection, and some will suffer severe disease. Globally, about 3.4% of reported COVID-19 cases have died. By comparison, seasonal flu generally kills far fewer than 1% of those infected." This was patently false. The coronavirus mortality rate reported by the media as stated by Dr. Ghebreyesus is completely inaccurate as all subsequent numbers show. The CDC lifted federal restrictions on coronavirus testing to allow any American to be tested for coronavirus, “subject to doctor’s orders.” The White House announced President Trump donated his fourth quarter salary to fight the coronavirus!
CHINA Mar 4: February rail freight loadings rise 4.5% YOY.
USA Mar 4: The Trump Administration announced the purchase of $500 million N95 respirators over the next 18 months to respond to the outbreak of the novel coronavirus. Secretary Azar announced that HHS was transferring $35 million to the CDC to help state and local communities that have been impacted most by the coronavirus
CHINA Mar 5: Shipments to foreign JIT customers upgraded: government subsidizes upgrades from sea to rail delivery and from rail to air delivery.
USA Mar 6: Question: How did the virus come to the United States?
Answer: “
The first known patients in the U.S. contracted the virus while traveling in other countries or after exposure to someone who had been to China or one of the other affected areas. But now, a few cases here cannot be traced to these risk factors. This is concerning because it suggests the illness may be spreading across communities for which the source of infection is unknown, which we call community spread/transmission. Dr. Emily Landon, spokesperson, U Chicago School of Medicine. President Trump signed an $8.3 billion bill to fight the coronavirus outbreak. The bill provides $7.76 billion to federal, state, & local agencies to combat the coronavirus and authorizes an additional $500 million in waivers for Medicare telehealth restrictions
USA Mar 9: HHS staffers often weren’t informed about coronavirus developments because they didn’t have adequate clearance. He said he was told that the matters were classified “
because it had to do with China.”
USA Mar 9: President Trump called on Congress to pass a payroll tax cut over coronavirus
USA Mar 10: President Trump and VP Pence met with top health insurance companies and secured a commitment to waive co-pays for coronavirus testing
USA Mar 11: White House
classifies coronavirus deliberations. The meetings at HHS were held in a secure area called a “Sensitive Compartmentalized Information Facility,” or SCIF, usually reserved for intelligence and military operations. HHS has SCIFs because theoretically it would play a major role in biowarfare or chemical attacks.
USA Mar 11: President Trump: Announced travel restrictions on foreigners who had visited Europe in the last 14 days; Directed the Small Business Administration to issue low-interest loans to affected small businesses and called on congress to increase this fund by $50bil
CHINA Mar 10: Government organizes and subsidizes bus, rail and air transport for two hundred million migrant workers to return to urban jobs.
USA Mar 12,: CDC director
Robert Redfield admits to a House Oversight Committee that some Americans who were diagnosed as dying from influenza tested positive for Covid-19 posthumously.
CHINA Mar 13: Chinese FM’s Lijian Zhao
demands US authorities reveal what they’re hiding about the origins of Covid-19. “When did patient zero begin in the US? How many people are infected? What are the names of the hospitals? It might be the US army who brought the epidemic to Wuhan. Be transparent! Make your data public! The US owes us an explanation!”
CHINA Mar 16: Ninety percent of businesses expected to resume full operations. All Apple stores open.
USA Mar 18: HHS temporarily suspended a regulation that prevents doctors from practicing across state lines
CHINA Mar 19:
No new corona virus cases.
USA Mar 19: President Trump Announced: Very encouraging progress shown by anti-malaria drug Hydroxychloroquine for fighting coronavirus; Carnival Cruise Lines will make ships available for use as hospitals in impacted areas to use for non-coronavirus patients; Vice President Pence announced tens of thousands of ventilators have been identified that can be converted to treat patients; The State Department issued a global level 4 health advisory, telling Americans to avoid all international travel due to coronavirus; President Trump directed FEMA to take the lead on the Federal Government’s coronavirus response & visited FEMA HQ with Vice President Pence for a video call with Governors
USA Mar 20: The U.S. and Mexico agreed to mutually restrict nonessential cross-border traffic; Secretary Mnuchin announced at the direction of President Trump that tax day will be moved from April 15 to July 15 for all taxpayers and businesses; President Trump: Spoke with Sen. Schumer about coronavirus response & stimulus measures; Held a call with over 12,000 small business owners to discuss relief efforts; Announced the CDC will invoke Title 42 to provide border patrol with tools to secure the borders. The Department of Education announced it will: Not enforce standardized testing requirements for the remainder of the school year; allow federal student loan borrowers to stop payments without penalty for 60 days. Secretary Azar announced: FEMA is coordinating and assisting coronavirus testing at labs across the country; The CDC is suspending all illegal entries to the country based on the public health threat, via Section 362 of the Public Health & Security Act; sent a letter to all 50 Governors announcing that the federal government is buying and making available 200,000 testing swabs
ITALY, March 27. Italian scientists investigate possible earlier emergence of coronavirus
Adriano Decarli, an epidemiologist and medical statistics professor at the University of Milan, said there had been a “significant” increase in the number of people hospitalized for pneumonia and flu in the areas of Milan and Lodi between October and December last year.
He told Reuters he could not give exact figures but “hundreds” more people than usual had been taken to hospital in the last three months of 2019 in those areas - two of Lombardy’s worst hit cities - with pneumonia and flu-like symptoms, and some of those had died. (see entry Oct-Dec 2019)
US, March 30: The U.S. Just Signed A $450 Million Coronavirus Vaccine Contract With Johnson & Johnson
The Trump administration is spending nearly half a billion dollars on one company in the race to find a coronavirus vaccine.
That’s according to a $456 million order with Johnson & Johnson’s Pharmaceuticals arm Janssen, which specified a “new vaccine asset for 2019 Novel Coronavirus (COVID-19),” Forbes found. It’s the largest reported amount spent on a vaccine project to date, even though the pharma giant hasn’t yet started any clinical trials as other firms have.
The deal was signed with the Health and Human Services Office of the Assistant Secretary for Preparedness and Response (ASPR) on March 27, 2020. It followed another order, made as part of the same contract with Janssen, for $150 million on March 20, 2020, for a “new antiviral” for COVID-19.
A spokesperson from Johnson & Johnson didn’t provide any more details on the specific order, but confirmed the $456 million award related to a collaboration with ASPR’s Biomedical Advanced Research and Development Authority (BARDA), as
announced in February. That work was built on previous contracts for developing countermeasures for other influenzas. The value of the coronavirus-specific work hadn’t previously been revealed and is the largest known contract for a coronavirus vaccine to date.
peterdobias.com
And if you have time, you can throw in royalty, and politicians...
