DMSO - Dimethylsulphoxide
- Thread starter Laura
- Start date
I'm thinking maybe 1 teaspoon DMSO and 1 teaspoon sodium ascorbate may still be too concentrated DMSO for topical use, because where I put it the skin turns a bit pink. I'm thinking of trying 0.5 teaspoon DMSO, 0.5 teaspoon Quinton isotonic, and 1 teaspoon sodium ascorbate.
Here's a very good review from Brayton (Cornell University), written in 1986:
www.ncbi.nlm.nih.gov
It's very complete and gives a good idea of what to expect in terms of side effects. DMSO's properties are reviewed and it's important to remember any potential toxic elements you might have been exposed shortly before (or after) using DMSO. There are reported cases of death because mercury was applied shortly before a topical DMSO in a horse.
DMSO has a sedative effect and it's also a good anticholinesterase chemical. That is, acetylcholine circulates better in the body after DMSO use:
www.britannica.com
DMSO's properties are reversible, including its ability to alter protein folding and/or configuration:
The chapter is too long to quote entirely, but it is highly recommended reading.
On a separate note, DMSO is compatible with stent materials except for those experimental stents that get purposely reabsorbed in the short-term. There is preliminary research to suggest that DMSO might prolong the life of the stents:
www.ncbi.nlm.nih.gov
Dimethyl sulfoxide (DMSO): a review - PubMed
Dimethyl sulfoxide (DMSO) is a very simple compound that has stimulated much controversy in the scientific and popular literature. Fig. 1 It is an aprotic solvent. Therapeutic and toxic agents that are not soluble in water are often soluble in DMSO. DMSO has a very strong affinity for water; on...
www.ncbi.nlm.nih.gov
It's very complete and gives a good idea of what to expect in terms of side effects. DMSO's properties are reviewed and it's important to remember any potential toxic elements you might have been exposed shortly before (or after) using DMSO. There are reported cases of death because mercury was applied shortly before a topical DMSO in a horse.
DMSO has a sedative effect and it's also a good anticholinesterase chemical. That is, acetylcholine circulates better in the body after DMSO use:
Anticholinesterase | Inhibitors, Alzheimer’s, Parkinson’s | Britannica
Anticholinesterase, any of several drugs that prevent destruction of the neurotransmitter acetylcholine by the enzyme acetylcholinesterase within the nervous system. Acetylcholine acts to transmit nerve impulses within the parasympathetic nervous system—i.e., that part of the autonomic nervous
www.britannica.com
DMSO's properties are reversible, including its ability to alter protein folding and/or configuration:
The chapter is too long to quote entirely, but it is highly recommended reading.
On a separate note, DMSO is compatible with stent materials except for those experimental stents that get purposely reabsorbed in the short-term. There is preliminary research to suggest that DMSO might prolong the life of the stents:
Dimethyl sulfoxide inhibits tissue factor expression, thrombus formation, and vascular smooth muscle cell activation: a potential treatment strategy for drug-eluting stents - PubMed
DMSO suppresses TF expression and activity, as well as thrombus formation; in addition, it inhibits VSMC proliferation and migration. Given its routine use in modern clinical practice, we propose DMSO as a novel strategy for coating drug-eluting stents and treating acute coronary syndromes.
www.ncbi.nlm.nih.gov
agirl
Jedi
I just have found dr.Morton Walker book in pdf.
Hope it is the right book
Hope it is the right book
It looks the same to me @agirl . I have an Apple e-book version and the chapters seem the same. The pdf is scanned but readable.
Thanks.
Yes, it could burn a little, but it should be temporary.
The book DMSO by Morton Walker is free in audiobook format on hoopla if your library participates.
I had this mixture sitting in a glass jar for a few days. My sodium ascorbate powder looks a white color, and over the days the mixture turned orange. I poured the whole thing on my leg to see what would happen. That night, my wife said she would get faint whiffs of the DMSO, and anything more would not be good.
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The DMSO loses its potency as it sits on open air. You have to close or seal it up.
I was going to try DMSO/Quinton injections in my backside to help with pain. I found some 20cc sterile syringes and 25g 1" sterile needles. I was planning on starting low with .5 or 1cc of DMSO and 10 ccs of quinton water and see how that works and increase the dose if needed. From what I've read 1" is enough to get it into the muscle. Do you know if 25g is too small of a barrel for the DMSO/Quinton injection?
25cc is too much for intramuscular use, there's risk of a sterile abscess. You could do 25cc subcutaneously though.
Subcutaneously, you can put up to 1000ml in practices like percutaneous hydrotomy and depending on the anatomical area covered (i.e. 1L subcutaneously for the entire vertebral column area through 24 subcutaneous needles). But intramuscular, I would not go beyond 12cc.
There is space for 12cc in all 10cc syringes. So 0.5cc up to 1 cc of DMSO and the rest physiological solution: total of 12cc of liquid.
Quinton is not a solution that is ideal for parenteral (intramuscular or subcutaneous) use because it has marine endotoxins. There are reported cases of sepsis. Even though these cases might have been immunocompromised patients, the warning is still valid.
If you are not sure about the differences between subcutaneous and intramuscular injections, I would get help from a health care provider.
Subcutaneously, you can put up to 1000ml in practices like percutaneous hydrotomy and depending on the anatomical area covered (i.e. 1L subcutaneously for the entire vertebral column area through 24 subcutaneous needles). But intramuscular, I would not go beyond 12cc.
There is space for 12cc in all 10cc syringes. So 0.5cc up to 1 cc of DMSO and the rest physiological solution: total of 12cc of liquid.
Quinton is not a solution that is ideal for parenteral (intramuscular or subcutaneous) use because it has marine endotoxins. There are reported cases of sepsis. Even though these cases might have been immunocompromised patients, the warning is still valid.
If you are not sure about the differences between subcutaneous and intramuscular injections, I would get help from a health care provider.
Thanks. I had a plastic lid over the glass jar, and the whole thing was in a sealed zip lock bag. Is that ok?
I guess I should stop using Quinton with DMSO, because I don't want DMSO to take the marine toxin through my skin. I'll use DMSO, distilled water, and sodium ascorbate.
