Mobile phone emission modulates inter-hemispheric functional coupling of EEG alpha rhythms in elderly compared to young subjects. med./biol.
By: Vecchio F, Babiloni C, Ferreri F, Buffo P, Cibelli G, Curcio G, van Dijkman S, Melgari JM, Giambattistelli F, Rossini PM
Published in: Clin Neurophysiol 2010; 121 (2): 163 - 171 ( PubMed Entry , Journal web site )
Aim of study (according to author)
In a previous study (Vecchio et al. 2007) it has been reported that GSM electromagnetic fields of a mobile phone modulate inter-hemispheric synchronization (an important physiological feature of information transfer into the brain) of temporal and frontal resting EEG rhythms in normal young subjects.
In the present study, the authors tested the hypothesis that this effect can vary with physiological aging as a sign of changes in the functional organization of cortical neural synchronization.
Background/further details:
Eyes-closed resting EEG data were recorded in 16 healthy elderly subjects (60.75 ± 2.87 years) and 5 young subjects (30 ± 1.26 years) in the same two conditions of the previous study (GSM device was turned on (45 min) in one condition and was turned off (45 min) in the other condition). The aging effects were investigated comparing the inter-hemispheric EEG coherence in the elderly subjects vs. a young group formed by 15 young subjects (including 10 young subjects of the previous study).
Individual EEG rhythms of interest were delta waves (about 2-4 Hz), theta waves (about 4-6 Hz), alpha wave 1 (about 6-8 Hz), alpha wave 2 (about 8-10 Hz) and alpha wave 3 (about 10-12 Hz).
Endpoint
effects on the neurological system: neural activity/EEG
Exposure
General category: mobile communication system, mobile phone, digital mobile phone, GSM
Field characteristics Parameters
902.4 MHz
pulsed (PW)
exposure duration: continuous for 45 min power: 2 W peak value
power: 0.25 W average over time
SAR: 0.5 W/kg max value (brain)
Exposed system:
human
partial body exposure: head (left side)
Methods
Endpoint/Measurement parameters/Methodology
effects on the neurological system: neural activity/EEG (estimation of functional connectivity; inter-hemispheric coherence analysis)
investigation on living organism
investigated organ system: brain/CNS
time of investigation: before and after exposure
Main outcome of study (according to author)
Compared with the young subjects, the elderly subjects showed a statistically significant increment of the inter-hemispheric coherence of frontal and temporal alpha wave rhythms (about 8-12 Hz) during the GSM condition. In conclusion, these data suggest that GSM electromagnetic fields of a mobile phone affect inter-hemispheric synchronization of the dominant (alpha wave) EEG rhythms as a function of the physiological aging. This study provides further evidence that physiological aging is related to changes in the functional organization of cortical neural synchronization.