Just stumbled upon a curious paper. Although it is a preprint and "hasn't been certified by peer review", there is some interesting info there. Apparently smoking (and older age) cause lower production or retantion of antibodies when vaccinating with Pfizer vaccine.
Objective We aimed to determine antibody (Ab) titres 3 months after the second dose of the BNT162b2 coronavirus disease-2019 (COVID-19) vaccine and to explore clinical variables predicting these titres in Japan. Methods We enrolled 378 healthcare workers (255 women, 123 men) whose blood samples...
www.medrxiv.org
They obviously see it as smoking and old age causing the vaccine not being as effective, and I certainly don't claim to understand the mechanism that well, but it's possible that it means that smoking may have a protective effect that causes better "antibody clearance". Here's why it may be useful:
Some time ago I saw the following quote in one of the papers in Russian. I'll attach it in case you are curious and know Russian. Anyways, here's what it says about the fact that antibodies for covid tend to disappear rather quickly:
It's also important to note that this paper was written in 2020, and Sputnik V was either only released or it was in the latest stages of production. So on one hand researchers could say now that since then they've reached a different conclusion, but on the other hand it could also provide us with an unbiased information.
The paper deals with various possible risks of vaccines that are based on adenoviruses.
Also based on the above, am I crazy to assume that smoking can be added to the pre and post vaccination protocol?
In Russian: