Is sodium ascorbate preferable to ascorbic acid just in the context of it burning less for intramuscular injections? Does the lack of pH change in NaA vs AA have any benefits, or make buffering less important?
I seem to remember in another thread somewhere that mixing pharmaceutical grade ascorbate with diluent at a high enough concentration will sterilize the solution because of how powerful an oxidant it is. Have any of you prepared mixtures for infusion on you own and had success?
There are answers to your questions in these sites posted previously in this thread:
If you are not familiarized with vitamin C’s miraculous record, now it is a good time to discover this treasure! First brought to my attention as a recommendation to a friend of mine who was critically ill, I was astounded to find out about the numerous testimonials around the world and its...
health-matrix.net
Yes, is very long, but very instructive and a must read for health care providers and if you are even remotely interesting in experimenting with this. I had an IV vitamin C injection with the ready-made stock solution that practitioners make themselves and found that all that I have written in the historical record is very important and to keep in mind. Depending on the context and state of health, this is something that you definitely need and want a health care provider to be around. Depending on the speed and concentration, you can certainly faint or even die if you have a glucose-6-phostate dehydrogenase deficiency.
Sodium ascorbate needs a small concentration of EDTA to neutralize the copper and iron which in turn neutralizes the ascorbate. No other additives are recommended.
Ideal dilutions for intramuscular injection are 500mg of C in 1cc of solution. Injection has to go deep in the muscle as there is subcutaneous induration and even sterile abscesses if the needle doesn't reach the muscle. Sodium ascorbate hurts less than ascorbic acid. As much as 2 grams can be injected in one site, but if the vials are of 1gram per 5cc, know that injecting 10cc in one single site might be too much, carrying a greater risk of complications if the water was not in the muscle to begin with.
Thrombophlebitis would always be an issue when using >500mg of vitamin C per cc and there is a possibility of fainting if solution goes too rapidly. Spacing the infusions or using a different vein are ways to allow the veins to recover.
For higher concentrations, calcium gluconate can be used to reduce tetany, but it can induce severe bradycardia in some populations. In fact, calcium gluconate is only used in the hospital setting.
There is more useful information in the historical record, a compilation of what they discovered in the past while applying vitamin C to patients throughout several decades. Fortunately, nobody needs to re-invent the wheel, but learn from practitioners in the past who in turn learned the hard way.
