I think there are genetic susceptibilities to psychopathy that can be worsened within particular environments. What I think has been demonstrated from several studies is that genes play a part, maybe a big part even if we don't know exactly what those genes are. Like anything else, say schizophrenia for example, those who suffer from symptoms show certain genetic similarities regardless of social background, although there may also environmental influences.
Looking at the genetic and developmental history of the individual as well as family members should give us some clues. I would say in the case of psychopathy there are ample clues regarding a genetic component.
Authors: Viding, Essi; Blair, R. James R.; Moffitt, Terrie E.; Plomin, Robert. Evidence for substantial genetic risk for psychopathy in 7-year-olds
journal of Child Psychology and Psychiatry (formerly Journal of Child Psychology and Psychiatry and Allied Disciplines); June 2005, Vol. 46 Issue: Number 6 p592-597, 6p
ISSN:
00219630; 14697610
Author Affiliations:
1Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
2Mood and Anxiety Disorders Program NIMH, Bethesda, MD, USA
Abstract:
Individuals with early warning signs of life-long psychopathy, callous-unemotional traits (CU) and high levels of antisocial behaviour (AB) can be identified in childhood. We report here the first twin study of high levels of psychopathic tendencies in young children.At the end of the first school year, teachers provided ratings of CU and AB for 3687 twin pairs from the Twins Early Development Study (TEDS). For the analyses of extreme CU, we selected same-sex twin pairs where at least one twin scored 1.3 or more standard deviations above the mean on the CU scale (612 probands, 459 twin pairs). For the analysis of extreme AB, we selected same-sex twin pairs where at least one twin scored 1.3 or more standard deviations above the mean on AB scale (444 probands, 364 twin pairs). Furthermore, the extreme AB sample was divided into those who were also extreme on CU (children with psychopathic tendencies; 234 probands, 187 twin pairs) and those who did not score in the extreme for CU (children without psychopathic tendencies; 210 probands, 177 twin pairs).DeFries–Fulker extremes analysis indicated that exhibiting high levels of CU is under strong genetic influence. Furthermore, separating children with AB into those with high and low levels of CU showed striking results: AB in children with high levels of CU is under extremely strong genetic influence and no influence of shared environment, whereas AB in children with low levels of CU shows moderate genetic and shared environmental influence.The remarkably high heritability for CU, and for AB children with CU, suggests that molecular genetic research on antisocial behaviour should focus on the CU core of psychopathy. Our findings also raise questions for public policy on interventions for antisocial behaviour.
Title: Biological and genetic factors in childhood psychopathy: A twin study.
Author: Ward, Michelle Caroline, U Southern California, US
Source:
Dissertation Abstracts International: Section B: The Sciences and Engineering, Vol 65(12-B), 2005. pp. 6679.
Publisher:
US: ProQuest Information & Learning.
ISSN:
0419-4217 (Print)
Order Number:
AAI3155495
Language:
English
Keywords:
biological factor; genetic factors; childhood psychopathy; twins; heart rate; skin conductance; caregiver reports; child self reports
Abstract:
Biological and genetic factors in childhood psychopathy were examined in a sample of 948 male and female twins (age 9-10). Childhood psychopathy was indexed by caregiver reports and child self-reports of the Childhood Psychopathy Scale (CPS). Psychometric analyses of the CPS factors indicated moderate psychometric properties for this measure, thus this study provided some support for the concept of childhood psychopathy. Contrary to findings from the adult literature, psychopathy group differences did not emerge for heart rate and skin conductance responses during the countdown paradigm in this study. Genetic analyses revealed substantial genetic and unique environmental influence for scores on the CPS. The genetic influences were largely non-additive (dominant) in nature. (PsycINFO Database Record (c) 2007 APA, all rights reserved)
A common genetic factor explains the association between psychopathic personality and antisocial behavior.
Title:
A Genetic Factor Explains Most of the Variation in the Psychopathic Personality.Find More Like This
Author(s):
Larsson, Henrik, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, henrik.larsson@meb.ki.se
Andershed, Henrik, Department of Behavioral, Social, and Legal Sciences, Orebro University, Sweden
Lichtenstein, Paul, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Address:
Larsson, Henrik, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, P.O. Box 281, SE-171 77, Stockholm, Sweden, henrik.larsson@meb.ki.se
Source:
Journal of Abnormal Psychology, Vol 115(2), May 2006. pp. 221-230.
Publisher:
US: American Psychological Assn
ISSN:
0021-843X (Print)
Digital Object Identifier:
10.1037/0021-843X.115.2.221
Language:
English
Keywords:
psychopathy; genetic factors; environment; twins; adolescence; psychopathic personality traits; sex differences
Abstract:
The psychopathic personality can be conceptualized as three interrelated dimensions, (a) an interpersonal style of glibness, grandiosity, and manipulation; (b) an affective disposition of callousness, lack of empathy, and unemotionality; and (c) a behavioral/lifestyle dimension of impulsivity, need for stimulation, and irresponsibility, underpinning a higher order construct, psychopathic personality. The authors used a self-report questionnaire (The Youth Psychopathic Traits Inventory) to study the importance of genetic and environmental influences on psychopathic personality traits in a sample of 1,090 monozygotic and dizygotic twin pairs, aged 16-17 years. Results showed a strong genetic influence behind the higher order "psychopathic personality" factor, underpinned by the three psychopathic personality dimensions. Over and above the effects to the higher order factor, significant unique genetic influences were also found in the callous/unemotional and in the impulsive/irresponsible dimension, but not in the grandiose/manipulative dimension. The authors propose that this latent psychopathic personality factor is a meaningful target for future etiological research. (PsycINFO Database Record (c) 2006 APA, all rights reserved)(from the journal abstract)
Title: A common genetic factor explains the association between psychopathic personality and antisocial behavior.
Find More Like This
Authors:
HENRIK LARSSON1
CATHERINE TUVBLAD2
FRUHLING V. RIJSDIJK3
HENRIK ANDERSHED4
MARTIN GRANN5
PAUL LICHTENSTEIN2
Source:
Psychological Medicine; Jan2007, Vol. 37 Issue 1, p15-26, 12p
Document Type:
Article
Subject Terms:
*DISEASES -- Causes & theories of causation
*GENOTYPE-environment interaction
*PSYCHOLOGY, Pathological
*DELINQUENT behavior
PSYCHOPATHY
Abstract:
Background. Both psychopathic personality traits and antisocial behavior are influenced by genetic as well as environmental factors. However, little is known about how genetic and environmental factors contribute to the associations between the psychopathic personality traits and antisocial behavior.Method. Data were drawn from a longitudinal population-based twin sample including all 1480 twin pairs born in Sweden between May 1985 and December 1986. The twins responded to mailed self-report questionnaires at two occasions: 1999 (twins 13–14 years old), and 2002 (twins 16–17 years old).Results. A common genetic factor loaded substantially on both psychopathic personality traits and antisocial behavior, whereas a common shared environmental factor loaded exclusively on antisocial behavior.Conclusions. The genetic overlap between psychopathic personality traits and antisocial behavior may reflect a genetic vulnerability to externalizing psychopathology. The finding of shared environmental influences only in antisocial behavior suggests an etiological distinction between psychopathic personality dimensions and antisocial behavior. Knowledge about temperamental correlates to antisocial behavior is important for identification of susceptibility genes, as well as for possible prevention through identification of at-risk children early in life. [ABSTRACT FROM AUTHOR]
************************************************************************
I am aware of the difficulties in separating genetic and environmental influences on a given phenotype, as well as separating multiple genes that may be involved in a particular phenotype. We can't really say there is one gene that identifies psychopathy and worse there are components of this disorder that shared with other disorders. However, as with most things that are deemed genetic, there are usually multiple genes and environment interactions involved which will be reflected in the degree that the person displays a trait and this is where a lot of confusion somes in. Furthermore, if the gene (s) that regulate a particular neurobiological or psychological function that affect behavior, say for example, shunting inhibition the pre-frontal cortex, or pre-pulse inhibition in amygdala; these activities can also be disrupted due to damage to the neural circuits involved at some point in an individual’s life resulting in similar behavior as a ‘core’ psychopath. This is what I guess you would term environmental effects. Any number of things can disrupt the electro-chemical balance that regulates our hypothetical shunting or pre-pulse inhibition via neurotransmitters .
So we see that in the various cases of neurobiological disruption leading to certain behaviors that can be due to genes and can also be to an environmental event during a developmental stage that affects how the genes regulating those activities function in adulthood. It still does not rule out genes.
So I would say that the underlying cause of psychopathy is disruption of the neurobiological systems involved in the function of emotion regulation, fear conditioning etc, executive control, risk taking behaviors etc., resulting in the core features two of which includes being callous and unemotional. Figuring out the actual cause of the disruption is the job of people like myself- neuroscientists, psychologist and developmental biologists. But it doesn’t mean others cannot understand or make use of our work, which I think is what is being done here as long as there is some understanding
As I said, I don’t entirely rule out that environment is involved but it seems to me that genes (the actual code there of or how they function and interact with the environment) have a lot to do with it. An individual can have the gene (s) of interest but never display the core traits as some environmental conditions may not be suited to the expression or function of the gene’s protein product. But we would still say that the person has a genetic risk for psychopathy whether they ever display the traits or not. We do this with other diseases to so why should psychopathy be an exception? I think there is a lot of politics (or maybe because psychopaths are in charge) involved with not wanting to go there with things involving personality and behavior.
Having a genetic component doesn’t always mean completely unable to remedy a problem, it just means we have to work harder at how we approach dealing with it. Consider also that an individual could have malfunctioning gene(s) but also other functioning genes that can regulate the same circuitry in normal manner. The brain is very redundant. Probably in those cases you won’t get the same degree of core features of a disorder. Thus the degree of expression of a given phenotype, like say psychopathy. will be based on many things; What multiple genes are involved in certain behaviors, how many are really “defective”, how many copies of a given defective gene (two or one) the person may carry, how many repeats within a particular area of the gene sequence and whether the version of a gene is long or short form etc AND the environment ( developmental etc). They are all good questions to ask and results from multiple studies have to come together to get a better picture. But how do you explain so called psychopaths that had "ideal' environmental upbringing and no *known* direct injury or pre and peri-natal exposure to damaging chemicals etc, but share a particular genotype and functioning brain circuitry with others who display similar traits? Again, you can’t always rule out everything but you can get to the most likely or dominant effects, and in such a case it would seem the genes are dominant.
Brain differences that are predictive for anti-social behavior are seen in very young children BTW and I am aware that genes are not the only mode of inheritance in biology, even if some neo-darwinists tend to promote it as the only one. I don’ think anyone is promoting that genes are the ONLY source of psychopathic behaviors but it is a strong causal component.
So in my view, multiple gene-gene interactions, as well as gene-environment interactions and plain ole environment (accidents, chemicals childhood diseases etc) can determine whether not someone displays characteristics of psychopathy, and to what degree it is displayed. In the core traits it looks like a developmental issue with a strong genetic component that I would even say genetic ‘cause’ of the traits that we observe (the science police aren’t around are they? LOL).
This website discuss current research with links to more research :http://personalitydisorders.suite101.com/articles.cfm
***********************************************************************
In 2004 a nice review was written on the issue including the need to address core psychopathy and anti-social disorder as well as genetic indications. Note there have since been some follow up studies addressing the issues raised in the paper. Loney et al (2007) found a strong correlation between maternal affective (the mothers are callous and unemotional) and these same core psychopathic behaviors in children. The mothers of course behaved in a hostile and dysfunctional manner and the authors suggest that this dysfunctional social environment the child is exposed to during development play a bigger role than assumed in other studies. I am guess this may be part of the ‘environment’ crowd’s evidence against gene. They authors went on to suggest that inherited characteristics could also be due to shared genetics that influence affect as well as shared hostile social environment. In my view, it is simpler to say they couldn’t rule out that genes which regulate the mothers behavior (low affect resulting in callousness etc) was also passed on to the child. As always correlation doesn’t mean causation. Also in the field, we are reluctant to say A cause B due philosophical issues regarding determinisms in science that has been written about extensively elsewhere, and also the way it has been used by bigots. Rather, we say A is involved in B but come on, we all know what is implied and it is disingenuous use this to rule out a phenomena that indications suggest is involved
I will put it in scientifically correct terms. Evidence from several studies ( Viding et al 2005., Ward, 2005, Larsson et al 2006, 2007) suggest there is a genetic component to core features of psychopathy. Twin studies show increased risk of core features of psychopathy among monozygotic twins compared to more distantly related family members. Although we do not know exactly what those genes are, they may be the same genes that are involved in the features of other psychiatric disorders showing certain of cognitive and affective symptoms. It seems this mode of inheritance is a key component of increased risk for displaying core features of psychopathy……blah blah blah
Annotation: Understanding the development
of psychopathy
Essi Viding
Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
Background: Psychopaths are not only antisocial, but also have a callous and unemotional personality
profile. This article selectively reviews evidence that psychopathic personality traits are an important
factor in understanding and predicting the development of persistent antisocial conduct. Cognitive
neuroscience research and more tentative genetic work on psychopathy will be discussed, especially as
they relate to possible developmental trajectories to psychopathy. Results: A personality-based
approach has been successful in clarifying the conceptual boundaries of psychopathy and delineating a
group of antisocial individuals with a distinct profile of offending and clear neurocognitive markers
indicating problems in processing distress in others and punishment directed to oneself. These markers
are also present in children with psychopathic tendencies, suggesting that psychopathy may be a
developmental disorder. The neurocognitive profile relates to the callous and unemotional personality
traits at the core of psychopathy and may index particular vulnerability to persistent antisocial conduct.
Preliminary twin studies suggest that personality traits at the core of psychopathy are much
more highly heritable than other personality traits. There are as yet no molecular genetic
studies of psychopathy. Conclusions: It is argued that an interdisciplinary approach that integrates
cognitive neuroscience and genetics will enhance understanding of the development of
psychopathy. Keywords: Psychopathy, psychopathic tendencies, antisocial behaviour, cognitive
neuroscience, behaviour genetics, Violence Inhibition Mechanism (VIM).
*
1Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK; 2Mood and Anxiety Disorders Program NIMH, Bethesda, MD, USA
Essi Viding, Social Genetic and Developmental Psychiatry Centre, Box Number P080, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK;
Email: spjgemc@iop.kcl.ac.uk
Abstract
This website discusses current research with links to more research which may have more up to date info. :http://personalitydisorders.suite101.com/articles.cfm
**************************************************************************************
Evidence for substantial genetic risk for psychopathy in 7-year-olds
* Essi Viding11Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK,
* R. James R. Blair22Mood and Anxiety Disorders Program NIMH, Bethesda, MD, USA,
* Terrie E. Moffitt11Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK, and
* Robert Plomin11Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
*******************************************************************************************
Another study:
Background: Individuals with early warning signs of life-long psychopathy, callous-unemotional traits (CU) and high levels of antisocial behaviour (AB) can be identified in childhood. We report here the first twin study of high levels of psychopathic tendencies in young children.
Methods: At the end of the first school year, teachers provided ratings of CU and AB for 3687 twin pairs from the Twins Early Development Study (TEDS). For the analyses of extreme CU, we selected same-sex twin pairs where at least one twin scored 1.3 or more standard deviations above the mean on the CU scale (612 probands, 459 twin pairs). For the analysis of extreme AB, we selected same-sex twin pairs where at least one twin scored 1.3 or more standard deviations above the mean on AB scale (444 probands, 364 twin pairs). Furthermore, the extreme AB sample was divided into those who were also extreme on CU (children with psychopathic tendencies; 234 probands, 187 twin pairs) and those who did not score in the extreme for CU (children without psychopathic tendencies; 210 probands, 177 twin pairs).
Results: DeFries–Fulker extremes analysis indicated that exhibiting high levels of CU is under strong genetic influence. Furthermore, separating children with AB into those with high and low levels of CU showed striking results: AB in children with high levels of CU is under extremely strong genetic influence and no influence of shared environment, whereas AB in children with low levels of CU shows moderate genetic and shared environmental influence.
Conclusions: The remarkably high heritability for CU, and for AB children with CU, suggests that molecular genetic research on antisocial behaviour should focus on the CU core of psychopathy. Our findings also raise questions for public policy on interventions for antisocial behaviour.
This article is cited by:
* Essi Viding, Alice P. Jones, Paul J. Frick, Terrie E. Moffitt and Robert Plomin. Heritability of antisocial behaviour at 9: do callous-unemotional traits matter?. Developmental Science doi: 10.1111/j.1467-7687.2007.00648.x
Abstract Abstract and References Full Text Article Full Article PDF
* Barbara De Clercq, Filip De Fruyt. (2007) Childhood antecedents of personality disorder. Current Opinion in Psychiatry 20:1, 57???61
CrossRef
* Daniel A. Waschbusch, Trudi M. Walsh, Brendan F. Andrade, Sara King, Normand J. Carrey. (2007) Social Problem Solving, Conduct Problems, and Callous-Unemotional Traits in Children. Child Psychiatry and Human Development 37:4, 293
CrossRef
* Bryan R. Loney, Angela Huntenburg, Carla Counts-Allan, Kelly M. Schmeelk. (2007) A preliminary examination of the intergenerational continuity of maternal psychopathic features. Aggressive Behavior 33:1, 14
CrossRef
* Bonamy R Oliver, Robert Plomin. (2007) Twins' Early Development Study (TEDS): A Multivariate, Longitudinal Genetic Investigation of Language, Cognition and Behavior Problems from Childhood Through Adolescence. Twin Research and Human Genetics 10:1, 96
CrossRef
* Véronique Dupéré, Éric Lacourse, J. Douglas Willms, Frank Vitaro, Richard E. Tremblay. (2007) Affiliation to Youth Gangs During Adolescence: The Interaction Between Childhood Psychopathic Tendencies and Neighborhood Disadvantage. Journal of Abnormal Child Psychology 35:6, 1035
CrossRef
* Michael A. Schonberg, Daniel S. Shaw. (2007) Do the Predictors of Child Conduct Problems Vary by High- and Low-Levels of Socioeconomic and Neighborhood Risk?. Clinical Child and Family Psychology Review 10:2, 101
CrossRef
* Daniel A. Waschbusch, Michael T. Willoughby. (2007) Attention-deficit/hyperactivity disorder and callous-unemotional traits as moderators of conduct problems when examining impairment and aggression in elementary school children. Aggressive Behavior ,
CrossRef
* Mark R. Dadds, Jennifer A. Fraser. (2006) Fire interest, fire setting and psychopathology in Australian children: a normative study. Australian and New Zealand Journal of Psychiatry 40:6-7, 581–586
Abstract Abstract and References Full Text Article Full Article PDF
* R.J.R. Blair, K.S. Peschardt, S. Budhani, D.G.V. Mitchell, D.S. Pine. (2006) The development of psychopathy. Journal of Child Psychology and Psychiatry 47:3-4, 262–276
Abstract Abstract and References Full Text Article Full Article PDF
* Joel T. Nigg. (2006) Temperament and developmental psychopathology. Journal of Child Psychology and Psychiatry 47:3-4, 395–422
Abstract Abstract and References Full Text Article Full Article PDF
* Paul J. Frick, Carrie Dickens. (2006) Current perspectives on conduct disorder. Current Psychiatry Reports 8:1, 59
CrossRef
* Craig S. Neumann, David S. Kosson, Adelle E. Forth, Robert D. Hare. (2006) Factor Structure of the Hare Psychopathy Checklist: Youth Version (PCL: YV) in Incarcerated Adolescents.. Psychological Assessment 18:2, 142
CrossRef
* J HILL. (2005) Conduct disorders. Psychiatry 4:7, 57
CrossRef
* Paul J. Frick, Carrie Dickens. (1996) Current perspectives on conduct disorder. Current Psychiatry Reports 8:1, 59
CrossRef
********************************************************************************************