Ketogenic Diet - Powerful Dietary Strategy for Certain Conditions

Re: Ketogenic Diet - Path To Transformation?

Oxajil said:
Gawan said:
A smaller update. It seems after over a year (should be August 2012 when I started) since starting the ketogenic diet that now my body is functioning normally, that means I can work the whole day and don't need a nap anymore, my legs feel energized and no cramps anymore. I did also some food experiments with Tomatoes and sweet pepper over the holidays and creme fraiche as I stated earlier and some mascarpone (but I don't like the taste). But these things seem to have a price too and may cause inflammation, since I need for the entire day much more insulin and getting spots in my face, but it is also an indicator what I shouldn't eat that often. So overall keeping myself to butter and meat seems to do the trick for me. Also my doctor was surprised when he noticed that the diabetic consequential damages getting better (they are tiny). He mentioned that it is very seldom, actually it should stay the same or getting worse, beside that I have a HBA1c like a healthy human being :D.

I'm also doing some EDTA rounds from time to time, every 3 month and some resistance training. Overall it may really depend how someone is doing on a KG-diet and may take really some time until the body gets fully adjusted, so patience is needed at least this was true in my case.

That's great news Gawan! :thup:

It really is great news! It's actually truly amazing that you've been able to make these kinds of improvements in a condition the medical establishment claims is hopeless. :)
 
Re: Ketogenic Diet - Path To Transformation?

That is great news Gawan! Congrats :clap:
 
Re: Ketogenic Diet - Path To Transformation?

Yeah, great to hear, Gawan. It also seems to me that if you could see the great benefits of KD, it really shows that when the "bugs are finally worked out," anyone can stick to it. The obstacles you had to overcome, are less severe in most people regarding insulin and blood sugar swings. So, it just shows that combining all the approaches to get into deep ketosis is doable for just about anybody. Thanks for sharing your update.
 
Re: Ketogenic Diet - Path To Transformation?

It is great news that things are evening out for you, Gawan. This is just superb!

As for the tomatoes and sweet peppers; they are nightshades and those are inflammatory for most people so there is no surprise there that they would cause you problems.

Keep up the great work with your diet. Onwards and upwards! :)
 
Re: Ketogenic Diet - Path To Transformation?

l apprenti de forgeron said:
Congratulations on the results of your effort and patience, Gawan! Keep up the great work you are doing. :cool2:
Make that another congratulations, Gawan. :rockon:


Edit: corrected spelling error!
 
Re: Ketogenic Diet - Path To Transformation?

Prodigal Son said:
l apprenti de forgeron said:
Congratulations on the results of your effort and patience, Gawan! Keep up the great work you are doing. :cool2:
Make that another congratulations, Gawan. :rockon:

DItto!

Great news, Gawan!

I can relate to the inflammation issues.

So far I'm almost a year on the KD and the results have been great, but as you said, I guess it takes a time until the body fully recovers from my previous years of detrimental diet.

I have noticed that I'm very sensitive to carbs now that I ate a few more carbs in during the holydays. I feel very different (mind fog, especially) and I start having craving right away

I can't tolerate butter, so I would say that lard and meat are just fine for me for now... I sometimes eat some veggies as well, some of them seem to be OK for me. Oh! and I have to add the cocoa (in small amounts since it has many carbs), that's fine too! :D
 
Re: Ketogenic Diet - Path To Transformation?

Way to go, Gawan! Even if I don't suffer from diabetes, it took me almost 1,5 years to fully adapt to the ketogenic diet. Persistence and consistency seems to be the key.

Congrats. :)
 
Re: Ketogenic Diet - Path To Transformation?

Read this interesting abstract online today - thought some of you might be interested!

The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer.

Poff AM, Ari C, Seyfried TN, D'Agostino DP.

INTRODUCTION:
Abnormal cancer metabolism creates a glycolytic-dependency which can be exploited by lowering glucose availability to the tumor. The ketogenic diet (KD) is a low carbohydrate, high fat diet which decreases blood glucose and elevates blood ketones and has been shown to slow cancer progression in animals and humans. Abnormal tumor vasculature creates hypoxic pockets which promote cancer progression and further increase the glycolytic-dependency of cancers. Hyperbaric oxygen therapy (HBO₂T) saturates tumors with oxygen, reversing the cancer promoting effects of tumor hypoxia. Since these non-toxic therapies exploit overlapping metabolic deficiencies of cancer, we tested their combined effects on cancer progression in a natural model of metastatic disease.

METHODS:
We used the firefly luciferase-tagged VM-M3 mouse model of metastatic cancer to compare tumor progression and survival in mice fed standard or KD ad libitum with or without HBO₂T (2.5 ATM absolute, 90 min, 3x/week). Tumor growth was monitored by in vivo bioluminescent imaging.

RESULTS:
KD alone significantly decreased blood glucose, slowed tumor growth, and increased mean survival time by 56.7% in mice with systemic metastatic cancer. While HBO₂T alone did not influence cancer progression, combining the KD with HBO₂T elicited a significant decrease in blood glucose, tumor growth rate, and 77.9% increase in mean survival time compared to controls.

CONCLUSIONS:
KD and HBO₂T produce significant anti-cancer effects when combined in a natural model of systemic metastatic cancer. Our evidence suggests that these therapies should be further investigated as potential non-toxic treatments or adjuvant therapies to standard care for patients with systemic metastatic disease.

Or in other words - the combination of ketogenic diet with hyperbaric oxygen therapy nearly doubled survival in widespread, advanced cancer.

Source and full-text (free PDF) here
 
Re: Ketogenic Diet - Path To Transformation?

Gawan said:
A smaller update. It seems after over a year (should be August 2012 when I started) since starting the ketogenic diet that now my body is functioning normally, that means I can work the whole day and don't need a nap anymore, my legs feel energized and no cramps anymore. I did also some food experiments with Tomatoes and sweet pepper over the holidays and creme fraiche as I stated earlier and some mascarpone (but I don't like the taste). But these things seem to have a price too and may cause inflammation, since I need for the entire day much more insulin and getting spots in my face, but it is also an indicator what I shouldn't eat that often. So overall keeping myself to butter and meat seems to do the trick for me. Also my doctor was surprised when he noticed that the diabetic consequential damages getting better (they are tiny). He mentioned that it is very seldom, actually it should stay the same or getting worse, beside that I have a HBA1c like a healthy human being :D.

I'm also doing some EDTA rounds from time to time, every 3 month and some resistance training. Overall it may really depend how someone is doing on a KG-diet and may take really some time until the body gets fully adjusted, so patience is needed at least this was true in my case.

Congratulations Gawan!
It is very good news and it is laudable your perseverance and how you overcome the difficulties. :hug2:

Mod's note: Edited to fix the quotation.
 
Re: Ketogenic Diet - Path To Transformation?

I found a good article outlining many important steps to gaining muscle that involve good diet.

_http://www.foodlogic.eu/article/2/10-reasons-why-you-are-not-gaining-muscle/

If you belong to this category and you want to know what’s wrong, here are top 10 mistakes you’re very probably doing.

1. You are not training hard enough or properly enough
This is the first thing I tell people who complain they can’t gain muscle. Their usual response is: “Definitely not! I’m doing my best!” And here’s usually the problem. People tend to do their best without bothering to find out what they should be really doing.

The biggest problems I notice people do in the gym:
-men tend to skip training important body parts, such as legs and back
-men prefer lifting heavy weights instead of focusing on proper form
-women don’t lift at all
-If you want to be efficient in the gym, do the following (applies to both men and women):

Look around your gym and find the most ripped guy there is. He should look like he weights around 70 or 75 kg tops.
Kindly ask him to teach you the proper form of every exercise, offering money in return.
Do those exercises with half the weight you were doing them before you were taught how to do them properly. Work out at least 5 days a week, 50 minutes a day.
That’s it!

2. You are not getting enough leucine
Leucine is one of the most important, key elements in building muscle. It’s an amino-acid which activates the mTOR protein, specifically mTORc1, which in turn activates the ribosomal protein S6 kinase beta-1, an enzyme responsible for muscle protein synthesis. Leucine is the only potent activator of mTOR. Other amino-acids which may also activate mTOR are isoleucine and valine, however, their potency is extremely weak.

Furthermore, approximately 5% of ingested leucine is metabolized into beta-hydroxy beta-methylbutyric acid (HMB), which effectively prevents the breakdown of muscle protein and thus protects the muscle. This metabolic pathway is the only source of HMB in the body.

Last but not least, leucine also promotes glucose uptake into muscle cells.

It should be noted that the mTOR pathway is anti-regulated by diabetes and obesity, which means that people with these conditions build muscle a lot slower and a higher intake of leucine is required to help activate the mTOR properly. Various other natural compounds, such as caffeine or curcumin, have been reported to inhibit mTOR after being applied to isolated cells. It’s therefore probable that these compounds should be avoided when building muscle; however, dietary research has yet to be done.

3. You are not getting enough Vitamin D3
Vitamin D3, also known as cholecalciferol, is a secosteroid, structurally similar to testosterone. In its metabolic pathway, it creates a hormone called calcitriol.

Studies show that calcitriol generally improves health, increases lifespan, leads to stronger teeth and bones, increases immunity, prevents and treats cancer, and also helps build muscle. It has also been shown to improve muscle strength, speed and endurance in athletes.

4. You are getting your protein from inappropriate foods
I’ve seen many people get their daily protein from ridiculously inappropriate foods, such as dairy. If 50% of your daily protein comes from cheese, yogurt or milk, you are not going to be building a lot of muscle. If you can’t fill your day with two chunks of meat and 4 eggs, don’t expect serious results.

5. Your diet does not allow your body to produce enough growth hormone
The human growth hormone, called somatotropin, stimulates cell reproduction and regeneration in humans – this includes building muscle. It’s produced naturally by the body, however, its production is reduced when you’re constantly eating and, on the other hand, enhanced by fasting. This is partially caused by insulin, whose high levels cause the body to stop producing sematotropin.

Why not both?
Your body wants to produce the most of somatotropin during your workouts, but when your insulin is elevated (because you were eating before going to the gym), the body is unable to produce it in significant amounts.

By fasting before and during your workouts, you cause your insulin levels to be low, making it possible for your body to produce high amounts of somatotropin, which when combined with high insulin levels after working out results in rapid cell regeneration.

6. Your insulin sensitivity is low (because of your diet)
Many gym-goers like to talk about how much food and how often they eat, yet they are not building any muscle. What they fail to realize is that their constant eating is exactly the problem.

To understand this problem, it’s very important to understand the role of insulin.

Insulin is a hormone produced by the human body which, apart of its many roles and purposes, increases glucose and amino acid uptake into muscle cells. Basically, whenever a compound wants to enter a cell, insulin must be present to allow this process. There are two factors defined here:

How much insulin your body produces and releases into the bloodstream. You want to have as much insulin as possible whenever you need to feed your muscle with amino acids.
How sensitive your cells are to insulin. You want your cells to be highly sensitive to insulin, so that any available insulin acts properly on the amino acid uptake.
The ideal way – what you should be doing
During longer periods of fasting (at least 12 hours), your insulin levels drop. This causes your cells to become more sensitive to insulin that remains present in the bloodstream and your body does not need to produce any insulin, so it becomes ready to produce it whenever necessary.

After this 12 – 16-hour period of fasting and after working out, when you have your first meal, you eat a lot of protein, which makes your body release a lot of insulin, to which your cells are highly sensitive and thus are forced to uptake the ingested amino acids into muscle cells.

What you are doing wrong
When you eat very often (for more than 12 hours a day), your body is forced to always produce insulin. Your insulin levels are always elevated and your cells become less and less sensitive to insulin; and when you need them to work properly after working out, they can’t do it. The amino acid uptake into your muscle cells is not as effective as it should be.

7. You aren’t getting enough sodium
Sodium is an electrolyte important for an enzyme called sodium-potassium adenosine triphosphatase (Na+/K+-ATPase), which is responsible for cellular health. Na+/K+-ATPase pumps three sodium ions out of the body cells for every two potassium ions to pump in. This export of sodium from the cell provides the driving force for several secondary active transporters membrane transport proteins, which import glucose, amino acids, and other nutrients into the cell by use of the sodium gradient.

Sodium also increases blood volume, which results in even better oxygen and nutrient delivery into cells.

Today’s recommended daily intakes of sodium are insufficient for physically active people, especially for people on a low-carb diet. To be sure that you are getting enough sodium, make sure your intake is at least 90% of what Foodlogic recommends to you.

8. You are eating too many carbohydrates (hoping they will build your muscle)
It’s believed by the uneducated and superstitious that carbohydrates build muscle. They don’t. Carbohydrates are non-essential nutrients which are not used by the body to build muscle.

One may argue that carbohydrates raise insulin, which is a good thing for a bodybuilder post-workout, and this is true, however, the disadvantages that come with carbohydrates always outweigh the advantages.

Carbohydrates also decrease insulin sensitivity (see #6).

Another problem with having too many carbohydrates in your diet is that they make you full while not providing any important muscle-building nutrients. Your stomach is full of food you don’t need. You feel full and you think you’ve provided your body with good food to build muscle and you don’t eat other really important foods.

Furthermore, the amino-acid profile of carbohydrates is not suitable for building muscle and it does not trigger muscle protein synthesis, so after eating a meal full of carbohydrates, you raise your insulin and blood glucose, but without protein synthesis activated, the insulin pumps glucose into your fat cells, which only makes you fat.

9. You are forgetting to eat all the other essential nutrients
So far I’ve talked only about the most important elements for building muscle. It’s important to know, however, that the whole essential nutrient profile is required for the proper body function, which ultimately leads to gaining muscle; and no, I won’t tell you to eat vegetables; vegetables are over-rated. They’re usually healthy if prepared correctly, but they hardly give you serious amounts of important nutrients. Use Foodlogic to know exactly what nutrients you need and what foods you’re best off eating to get them.

10. You are not getting enough sleep
Never underestimate the power of sleep. When sleeping, you regenerate very quickly and efficiently. Some regeneration processes are triggered only during the sleep. Get at least 7 – 8 good hours of sleep every night if you are physically active.

Too long? Didn’t read?
If you found this article too long to read and you scrolled down to the end to find a magical technique to build muscle, or you’ve read the article and still don’t know what to do, here’s the summary of what you should be doing:

-Train often. Focus on proper form.
-Supplement leucine. If you want to know how much, use Foodlogic.
-Supplement Vitamin D3. If you want to know how much, use Foodlogic.
-Don’t eat too much dairy. Eat more meat and eggs.
-Eat a low-carb diet combined with intermittent fasting.
-Add salt to your foods.
-Eat healthy food full of essential nutrients. Foodlogic will help you with that!
-Sleep a lot.
 
Re: Ketogenic Diet - Path To Transformation?

Hi whitecoast,

Thanks for posting this article - quite interesting.

While he mentions a few very important points, I don't agree with some things he says, because it seems to me, that he still is mired in the carbohydrate controversy. He is talking about a low-carbohydrate diet - how low, I don't know, but he certainly doesn't advocate a ketogenic diet. A KD (plus or minus intermittent fasting) is an entirely different kettle of fish - you will grow muscle bulk under a KD without exercise. This might be counterintuitive, but most of us who have been on a KD for a significant amount of duration will tell you that. It's either Nora G. or Mark S. who gives the example of polar ice-bears, who have their biggest muscle bulk after they wake up from hibernation - and it goes down steadily as the season progresses.

That doesn't mean we shouldn't do any exercise - but for different reasons, and probably in a different way too. Well, it depends what you want. I for one am not interested in a ribbed abdomen and pumped-up muscles. I want to trigger the wild mitochondrial DNA to get rid of hybrids as well as I can to reverse mitochondrial dysfunction. I want my body to function optimally and want to be able to have the speed, endurance and muscle strength to escape out of a tight corner. This doesn't require bulky muscles, quite the opposite is true. Look at a picture of a bushman - the are very lean, sinewy and do have well-defined muscles, but they resemble in no way any of those pumped up guys one frequently finds in gyms. So far as I have researched, the best exercise is a mixture of eccentric resistance training (ERT) and high-intensity interval training (HIIT). I do HIIT about once every 7 - 10 days and ERT around every other day. If my muscles still feel tired, I'll give it another day of rest. Resting is pretty much as important as training. More than 3 of these sessions per week probably are counterproductive. More exercise than that also has another downside, especially in conjunction with a significant glucose metabolism - the production of free radicals (or reactive oxygen species, ROS), which are associated with aging.

The other thing is the mTOR thing. I must admit that I haven't studied the mTOR pathway in an detail yet - something that has been on my list of things to do for a considerable time, but that I haven't tackled yet. Maybe time to do now. Anyway, as far as my limited knowledge in this area goes, what I have understood so far is that for optimal results one should endeavour to avoid stimulating the mTOR pathway as much as possible - similar to insulin on the glucose side. He advocates stimulation of insulin for muscle bulk after exercise by ingesting carbs, and he advocates the same thing on the protein side. I for one try to keep my insulin levels down as much as I can at any time possible. And presumably this is the case too with the mTOR pathway - but I stand to be corrected, as I haven't dug into this well enough.

So in summary, while I think he mentions a few valid points, his outlook is a totally different one than my (or our) outlook, so I couldn't endorse his recommendations as they stand here.
 

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