I did the DMSA provocation test -- it's harder to get ahold of DMSA than last time I did this because of the increased regulation against it, but I was able to get some through a compounding pharmacy.shijing, that it is a real shame. Did you do the DMSA provocation test, or was that a one-time urine sample?
Yeah, me too -- I'm not physically addicted, but I am psychologically dependent on it, especially for stress relief (I also spend a lot of time in front of my computer, and smoke breaks are one thing I use to make sure I don't sit for too long at one time). I went for a month without smoking in January 2017 and didn't have any physical withdrawal symptoms, but I did miss it during that time and was tempted to fill the gap by snacking in a way that I didn't usually experience, so if I do quit it will take some willpower to not compensate with other unhealthy habits.I have recently been considering doing something similar about the tobacco. I suspect that, either due to the land it is grown on, or some processing method, tobacco is loaded with metals and probably glyphosate. Quitting is starting to look like a real possibility, and I never thought I would say that :(
Thanks -- I suppose there's no easy way to tell which is the case, which is frustrating. But even if it is the case that I was doing a good job of detoxifying the mercury and the levels in my report are deceptive, there's apparently something in my environment that's exposing me to mercury (or else I wouldn't be excreting it in the first place), so I guess the wisest thing to do is to proceed with the chelation.On the results of your test, since it was urine, the high mercury is not necessarily reflective that you have toxicity. Sometimes it might reflect that your body is doing a good job at detoxifying it. On the other hand, you could be right that there is an issue there. Either way, good luck with chelation!
Its not really an area that I have much knowledge in, but from what I understand a paleo/ketogenic diet tends to elevate creatinine slightly. A moderate increase is not necessarily bad (I don't think). Meat, especially of the red variety, is really high in creatine content, and creatine is converted into creatinine.There's one other thing I was wondering about -- when I do regular bloodwork, my creatinine levels are usually in the higher part of the normal range, but they're normal nonetheless. But I noticed in this test that my creatinine level is elevated (which wasn't the case in the previous heavy metal challenge tests I did). Is there anything that could be causing that elevated number besides actual kidney dysfunction?
Thanks for your feedback, Keyhole, especially what you mentioned about urine levels of creatinine not being as reliable as serum levels, since the latter are what show my creatinine to be within the normal range. Thanks also for trying to find info about DMSA and creatinine. The other factors you mentioned could certainly be a part of it as well -- meat consumption and exercise (I try to get regular exercise, but probably don't get as much as I should). I have a follow-up appointment with my doctor next week, and I'll also ask her about this then.Its not really an area that I have much knowledge in, but from what I understand a paleo/ketogenic diet tends to elevate creatinine slightly. A moderate increase is not necessarily bad (I don't think). Meat, especially of the red variety, is really high in creatine content, and creatine is converted into creatinine.
Apparently urine levels of creatinine are not as reliable as serum levels. You could keep an eye out for your next blood work to check the creatinine levels on that in case you are worried. I know that EDTA chelation can temporarily alter creatinine clearance, and there is also some research on nephrotoxicity at higher doses. But you took a small amount of DMSA, and I couldnt find any research on that.
Excessive or lack of exercise and other things can also alter creatinine clearance. But take this all FWIW, since I am not a doctor! You could ask your doc about it if you are concerned, or maybe one of the docs on this forum may be able to chime in.
Thanks for your feedback too, Gaby. It's a little frustrating that the detox amounts can vary from cycle to cycle, since we can't do repeated tests (it's cost-prohibitive) to monitor the ongoing amounts of metals that we're unloading as we go. Your point is well taken, though, and I'm glad that when you did the test you saw solid results from the detox and that your body wasn't stubborn about sequestering the metals. I agree that it's a good idea to move forward with the detox for now, and then I do want to recheck my levels, maybe toward the end of this year.What I would keep in mind is that mercury detox can be erratic. For instance, you can do 6 cycles of DMSA and get absolutely nothing released in the first few cycles. Then everything comes out on the 5th. In "Detoxification and Healing", I think the author used the analogy of dirty socks in the washing machine. That is, it's not like that at all. You might start by detoxing a lot, and then there is a stagnant period and then stuff comes out again. It is not predictable when and where mercury will come out in respect to the detox cycles.
When I had my DMSA urine challenge test, I was happy to see that at least a bunch of stuff was coming out with the DMSA. It could have been worse... Stuff could have stayed inside.
Might be worth re-checking down the road. In the time being, I think that detox efforts are well spent.
That looks like a good deal. Is there any particular reason to favor a DMSA provocation over a DMSA+EDTA provocation? I'm looking around and it looks like they can pick up different things, but due to the costs of testing I'm wondering if you start to get diminishing returns if you look into additional chelators.For those in the states, I found this lab in Illinois that does heavy metal testing for $129.95, postage paid and they include the DMSA you need to take as well. Urine Challenge Test for Heavy Metals Using DMSA
The results look similar to Joe's test results. They test for 20 different metals. Seems like a pretty decent deal.