Boston University CREATES a new Covid strain that has an 80% kill rate — echoing dangerous experiments feared to have started pandemic
Boston University CREATES new Covid strain that has an 80% kill rate
News Source is questionable so take it with a grain of salt.
The article is as follows ...
'US researchers have developed a new lethal Covid strain in a laboratory – echoing the type of experiments many fear started the pandemic.
The mutant variant — which is a hybrid of Omicron and the original Wuhan virus — killed 80 percent of mice infected with it at Boston University.
When a similar group of rodents were exposed to the standard Omicron strain, however, they all survived and only experienced 'mild' symptoms.
The scientists also infected human cells with the hybrid variant and found it was five times more infectious than Omicron.
This suggests the man-made virus might be the most contagious form yet.
It will no doubt surprise many Americans that such experiments continue to go on in the US despite concerns similar studies may have led to the global Covid outbreak.
Covid first began spreading from a wet market in Wuhan, China, about eight miles from a similar high-security virology laboratory that manipulated bat coronaviruses.
Chinese scientists were found to have wiped crucial databases and stifled independent investigations into the facility's links to the pandemic.
In the new research, which has not been peer-reviewed, a team of researchers from Boston and Florida extracted Omicron's spike protein — the unique structure that binds to and invades human cells.
It has always been present in the virus but has become more evolved over time. Omicron has dozens of mutations on its spike protein that made it so infectious.
Researchers attached Omicron's spike to the original wildtype strain that first emerged in Wuhan at the start of the pandemic.
Writing in the paper, they said: ‘In...mice, while Omicron causes mild, non-fatal infection, the Omicron S-carrying virus inflicts severe disease with a mortality rate of 80 percent.’
The researchers said it signaled that while the spike protein is responsible for infectivity, changes to other parts of its structure determine its deadliness.
The scientists also looked at the different strains' effect on human lung cells that were grown in the lab.
Covid latches onto human cells with its spike protein, and instructs healthy cells to produce copies of itself.
Scientists measured how many copies each variant caused the health cells to produce.
They found the hybrid strain produced five times more viral particles than the original Omicron.
The scientists admit the hybrid virus is unlikely to be as deadly in humans as it was in mice.
This is because the specific breed of lab mice used are very susceptible to severe Covid disease. Mice and humans also have very different immune responses to the virus.
The lab, at Boston University's National Emerging Infectious Diseases Laboratories, is one of 13 biosafety level 4 labs in the US.
These are labs that are authorized to handle the most dangerous pathogens. There are also facilities in Texas, Atlanta and Manhattan, Kansas.
Experiments at these labs often involve tinkering with animal viruses to advance treatments and vaccines that could be used in a future outbreak.
Work on the live virus that causes Covid must be carried out at a BSL-3 or BSL-4 lab.
In BSL-3 labs, researchers do all experiments in a ‘biosafety cabinet’ — an enclosed, ventilated workspace for handling materials contaminated with pathogens.
The labs also have self-closing doors, sealed windows, floors and walls, and filtered ventilation systems.
In a BSL-4 lab, full-body, air-supplied pressure suits are worn and workers must change their clothing before entering and shower before leaving.
The lab is situated in a separate section of the building and has its own dedicated air supply.
The 'lab leak' origin theory for Covid was initially dismissed as conspiracy at the start of the pandemic in favour of a natural emergence.
But the hypothesis gained momentum following a series of revelations and cover-ups.
Crucial information about the earliest infected patients was wiped from the Wuhan lab's database in late 2019 and one of its staff vanished after coming down with a mysterious flu-like illness.'
More fear tactics, Haiku ...
On Byram Bridle's substack, he offers further news on this newly engineered Corona virus
(to recall, Byram Bridle sparked intense debate when he got a hold of the Pfizer study from Japan that showed the nanoparticles were not staying at the injection site, but found in the ovaries, heart, etc)
Lab in Boston Made What Could Be A Super-Killer SARS-COV-2
Extreme Danger: This is Gain-of-Function Research on Steroids
Dr. Byram W. Bridle
Oct 18
I was in shock when a couple of my colleagues directed me to a pre-print article that was posted online on Friday October 14, 2022. Pre-prints are scientific papers that have not yet undergone peer review and they have not been published in a journal. In this case, these nuances are moot. What is far more important is the product that has been described, along with the disclosure of the recipe to make it.
You can find the pre-print article at this
link.
Here is the full citation:
Title: “Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron”
Authors: Da-Yuan Chen, Devin Kenney, Chue Vin Chin, Alexander H. Tavares, Nazimuddin Khan, Hasahn L. Conway, GuanQun Liu, Manish C. Choudhary, Hans P. Gertje, Aoife K. O’Connell, Darrell N. Kotton, Alexandra Herrmann, Armin Ensser, John H. Connor, Markus Bosmann, Jonathan Z. Li, Michaela U. Gack, Susan C. Baker, Robert N. Kirchdoerfer, Yachana Kataria, Nicholas A. Crossland, Florian Douam, Mohsan Saeed
bioRxiv 2022.10.13.512134
doi:
https://doi.org/10.1101/2022.10.13.512134
The Purported Intent of the Research
The bulk of the research, and the most dangerous aspects, were conducted at Boston University in Massachusetts, USA. In a nutshell, the authors made a ‘chimeric’ version of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), which is the causative agent of the coronavirus disease that was first identified in 2019 (COVID-19). A chimera is a combination of two different biological entities. For example, my academic institution’s mascot is a gryphon, which is a combination of a lion and an eagle…
In the case of the paper in question, they made a SARS-CoV-2 that was part Omicron variant (the spike protein) and part ‘ancestral’ variant (meaning it was a variant from earlier in the declared pandemic). Apparently, they were trying to figure out what role the spike protein has played in the ability of the Omicron variant to escape the far-from-sterilizing COVID-19 jab-induced immune responses, as well as its role in pathogenicity (how the virus causes disease).
Here it is in the authors’ words:
“We generated chimeric recombinant SARS-CoV-2 encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate and compared this virus with the naturally circulating Omicron variant.”
I don’t care what the hypothesis of the study was. The results are nightmarish.
To the Point: A Super-Deadly SARS-CoV-2 was Engineered
When the chimeric SARS-CoV-2 was tested in mice that express the same high-affinity viral entry receptor that people do, the authors dropped this bombshell…
“…while Omicron causes mild, non-fatal infection, the Omicron S-carrying virus inflicts severe disease with a mortality rate of 80%.”
Yes, you read that correctly. The 23 scientists that conducted this research took a SARS-CoV-2 that is no more dangerous than the annual flu for people under 40 years of age and turned it into a virus that can kill 80% of its hosts!!!!!
To put this into perspective, nightmarish movies have been made about the horrors of outbreaks of Ebola virus, which has an average case fatality rate of 50% (as per the World Health Organization; WHO). Infamous signs of hemorrhagic fever in some people include bleeding from the eyes and other orfices.
The WHO has also reported an average case fatality rate of 50% for the deadly Marburg virus.
So, 23 scientists in the USA now have a virus in their hands that could be much more deadly than the Ebola and Marburg viruses.
Take some time to think about this.
This is appalling.
This is a classic example of gain-of-function research.
It was gain-of-function research that resulted in SARS-CoV-2 in the first place. People like U.S. senator and physician Rand Paul have essentially proved this fact. Notably, while squirming under Senator Paul’s questioning, Anthony Fauci repeatedly denied ever funding gain-of-function research, let alone with respect to SARS-CoV-2. With this in mind, note one of the key sources of funding for this current research that has generated a super-deadly SARS-CoV-2; as disclosed by the authors…
“National Institutes of Health, NIAID grants R01 AI159945 (to SB and MS) and R37 AI087846 (to MUG)”
NIAID is the National Institute of Allergy and Infectious Diseases, of which Anthony Fauci is the director! I am keen to see if Fauci will still declare under oath that his agency has never funded gain-of-function research related to SARS-CoV-2.
Why The ‘Monster’ SARS-CoV-2 Is Much More Dangerous
In most people, the Omicron variant of SARS-CoV-2 typically causes only mild COVID-19, if any disease at all. This is in large part due to it being limited to infecting only the upper airways. In contrast, earlier versions of SARS-CoV-2 could infect the lower airways in some people where it could cause severe pneumonia in high-risk individuals; a demographic that has been well-defined for most of the declared pandemic.
Some scientists have been forewarning for quite some time that if a variant of SARS-CoV-2 were to emerge that had the infectivity and immunoevasive properties of Omicron, but could get deep into the lungs like earlier variants, the results could be deadly. With this in mind, here is what the authors of the pre-print article had to say about their virus…
“…unlike naturally occurring Omicron, [the chimeric SARS-CoV-2] efficiently replicates in cell lines and primary-like distal lung cells.”
…translation: the chimeric SARS-CoV-2 has the potential to cause infections deep in the lungs, where severe pneumonia would be the expected outcome. Indeed, in the mice that were killed, the virus seemed to preferentially infect the lower airways.
We may have been on our way to naturally selecting such a variant of SARS-CoV-2 through the completely inappropriate global use of COVID-19 inoculations that apply a non-lethal selective pressure. Twenty-three American scientists have inadvertently provided the proof-of-principle that emergence of a potentially deadly SARS-CoV-2 is possible. The problem is, this virus is no longer theoretical. Nor is it a potential future concern. It exists now; in laboratories in Boston.
It Gets Worse: Providing a Recipe for a Super-Pathogen
A good scientific paper should be written in such a way that other scientists in the respective field(s) of expertise could repeat the experiments to determine whether or not the results can be replicated. I am a viral immunologist and I reviewed the materials and methods section. I am confident that my research team could use this information to make the same chimeric virus. My team would never do this. However, I cannot speak to the morality of potential bioterrorists who could just as easily replicate the work should they have access to basic laboratory facilities.
In essence, the 23 authors of this paper have provided a recipe for a potent bioterrorism agent. It is in the public domain and can no longer be eliminated from cyberspace.
Remarkably, It Gets Even Worse
The naturally occurring SARS-CoV-2 is what is known as a ‘containment level-3 (CL-3) pathogen’ (Americans would call it a ‘biological safety level-3 pathogen’). This means that research with this virus must be conducted in a CL-3 facility. Such facilities have sufficient biosecurity to keep a CL-3 pathogen contained. A major potential problem with gain-of-function research is that it can amplify the danger and/or infectivity of a pathogen. This is exactly what happened in the current case.
In short, the research project started with a non-lethal SARS-CoV-2. What emerged is a virus with the potential to be a super-killer. This means that the 23 authors of the article ended up with a CL-4 pathogen housed in a CL-3 facility.
The latter type of facility is not designed to contain a CL-4 pathogen!
This is an excerpt from the materials and methods section of the paper…
“All procedures were performed in a biosafety level 3 (BSL3) facility at the National Emerging Infectious Diseases Laboratories of the Boston University”
Here is how the United States Centers for Disease Control describe pathogens that must only be handled within CL-4 facilities…
“The microbes in a BSL-4 lab are dangerous and exotic, posing a high risk of aerosol-transmitted infections. Infections caused by these microbes are frequently fatal and without treatment or vaccines. Two examples of microbes worked with in a BSL-4 laboratory include Ebola and Marburg viruses.”
- Can SARS-CoV-2 be transmitted via aerosols? Yes
-Is the chimeric SARS-CoV-2 frequently fatal? Yes, 80% of the time
-Do effective treatments exist? The most effective ones have been outlawed
-Do effective vaccines exist? No. Laughable vaccine-wannabes exist, though.
-Is chimeric SARS-CoV-2 as dangerous as Ebola/Marburg viruses? Likely more so
So, should the chimeric SARS-CoV-2 have only been handled in a CL-4 facility. Yes, but, “All procedures were performed in a biosafety level 3 facility”.
If this virus were to get released into the public, it could result in a global catastrophe. Although this virus was not evaluated in humans, pre-clinical studies are used to try to predict what would happen in people. There is the theoretical potential for the virus to be less or equally deadly in people as compared to mice. However, for all we know, the virus could be even more deadly in people than it was in mice!
Action Must Be Taken Immediately: Reckless Science Must Be Stopped
1. Gain-of-function research with pathogens should be outlawed around the globe. Highly infectious viruses have no respect for borders.
2. Chimeric SARS-CoV-2, a CL-4 pathogen, was handled under CL-3 conditions. All stocks of this virus should be destroyed as soon as possible. All people who worked with this virus and their contacts should be tested via sequencing to determine if there is any evidence of this virus having been released.
3. Agencies like Fauci’s NIAID should be investigated and questioned as to why they are actively funding gain-of-function research with SARS-CoV-2, which was itself the result of gain-of-function research. The fear-mongered over-reaction to the original version of their virus massively disrupted the global population. Continuing to manipulate this virus should be investigated as potential criminal behaviour.
4. The twenty three scientists who engineered the far more dangerous SARS-CoV-2, as well as Boston University, should be investigated and their research sanctioned. They have demonstrated grossly reckless scientific behaviour.
5. Unfortunately, not much can be done about the fact that a recipe for a super-deadly SARS-CoV-2 is now in the hands of any interested bioterrorists who have read or will read the pre-print article.
Gain-of-function research does not represent the only option to study pathogenicity and infectivity of a pathogen. Even if questions arise that cannot be definitively answered in the absence of gain-of-function research, those would be questions that should be left unanswered. The risk exceeds any benefit. Science should not be practiced completely unfettered.
