Apologies for the length of the post. Some info is a repost from another thread that is hopefully informative and helpful, especially for those with autoimmune, hypothyroidism symptoms, those having reactions at low(er) doses, and if you are feeling yucky/toxic, e.g. something just not feeling "right. " Second half of the post is my experimenting with MSM, and some wonderful results with regard to hypo symptoms and feeling toxic.
Gist of it all is the gut/liver/adrenals/gallbladder not functioning properly can all lead to low thyroid activity which can then cause many other issues. Adding iodine, with the proper cofactors may help activate the thyroid, or it may be necessary to first do some “pump priming” either with cofactors along with a few additional supplements and/or along with some thyroid activating organic materials (forms of kelp preferably from Atlantic).
Low thyroid is very common, especially in the US.
high estrogen ---> low thyroid
adrenal (high cortisol) issues ----> low thyroid/fatigue/low immune function
liver issues ------> low thyroid/impaired T4 to T3 conversion
Leaky gut ------> low thyroid, low stomach acid
Low stomach acid ----> impaired absorption mineral/vitamin/protein------>low thyroid
This may account for why some people are having much easier time with iodine, as they've had good cleaning through diet, supplements, etc., which already had thyroid functioning better, whether they knew it or not. All of that would make the detox much smoother when iodine starts kicking halides/metals out.
If those organs are already impaired by bad diet, toxin buildup, detox pathways blocked, etc., then adding iodine detox can overwhelm them all, causing many symptoms (some of which can be due to candida overgrowth.)
Many of pieces of a puzzle to put together.
These first two videos do a good job of showing the whole picture/relationship.
How to Have a Healthy Thyroid
__https://www.youtube.com/watch?v=BTNhlkOW9qc
How to Heal Thyroid and Adrenal Fatigue
__https://www.youtube.com/watch?v=F1rxW9IzYrA
The next three go into detail on each "link/interaction." He does have products for sale which are briefly mentioned, but they are not "sales pitch" videos.
The Thyroid Gland and the Estrogen Connection
__https://www.youtube.com/watch?v=GgfWsp0hqYc&list=PLVLP-bhbxACZ322PIWZ-FBvXzjqUBtG4I&index=2
What's Really Behind a Sluggish Thyroid Problem
__https://www.youtube.com/watch?v=pm49uFWTYBI&index=7&list=PLVLP-bhbxACZ322PIWZ-FBvXzjqUBtG4I
Most Thyroid Issues Are Secondary to Other Problems
__https://www.youtube.com/watch?v=IdDMMs96N9A
Another site below, has much of the information contained in this thread, with some additional, and it may come in handy as quick reference for those who don’t have the books.
The main iodine page is here, with the menu on the right providing navigation to other sections and subsections. They quote Browenstein, Flechas, etc.
__http://healyourselfathome.com/HOW/NEWSTARTS/1_NUTRITION/MINERALS/IODINE/HOW_TO_SUPPLEMENT/sources_of_iodine_iodide.aspx
Direct link to Thyroid Disorders section.
__http://healyourselfathome.com/HEALTH_PROBLEMS/THYROID_DISORDERS/THYROID_DISORDERS_MAIN.aspx
I continued to have hypothyroidism symptoms, namely gnawing/burning/lump throat sensation, sometimes just the thyroid area, while other the entire throat, cold hands/feet, fatigue (adrenal fatigue), and dry skin, while only taking a thyroid activator with very little iodine (less than 500 mcg). I tried several times to add iodine, anywhere from 1 mg liquid, up to 6 mg capsule, and each time it would significantly worsen the hypo symptoms. They could be somewhat relieved by adding more selenium (up to 800 mcg spread during the day) and zinc (gluconate form up 50 mg day). All the while, I continued with blessed salt water and chlorella. Nevertheless in addition to those symptoms I still “felt” slightly toxic and even had some symptoms of same (tongue swollen/indentations from teeth and lymph nodes in neck swollen at times).
Continued searching hypothyroidism and kept running into MSM, methylsulfonylmethane, which has been covered in the forum in general, and just a few here in the thread have indicated they were taking it.
Article on MSM
“MSM, which is a metabolite of DMSO, and approved for use in humans, primarily impacts your health by reducing inflammation. It’s widely used as a supplement for arthritic conditions. Like DMSO, MSM also appears to improve cell wall permeability, so it can be used to help deliver other active ingredients. Perhaps most important, MSM helps protect against oxidative damage.”
“As I mentioned earlier, sulfur plays an important role in the production of glutathione—one of the most important antioxidants that your body produces. Glutathione also serves important functions for detoxification. Without sulfur, glutathione cannot work. So, while not an antioxidant by itself, part of MSM’s action is to improve your body’s ability to make its own antioxidants.”
__http://articles.mercola.com/sites/articles/archive/2013/03/03/msm-benefits.aspx
“Organically bonded sulfur is a component of all proteins, such as the amino acids cysteine and methionine. Disulfide bonds are largely responsible for the strength and shape of proteins. Since sulfur bonds are required for proteins to maintain their shape, and these bonds determine the biological activity of the proteins, we can see why sulfur is critical for health and life itself. There is no doubt that sulfur helps us battle cancer so it’s a good time to become more familiar with this basic element.
Sulfur is required for the proper structure and biological activity of enzymes. If you don’t have sufficient amounts of sulfur in your body, the enzymes cannot function properly. This can cascade into a number of health problems since, without biologically-active enzymes, your metabolic
processes cannot function properly.
“Mercury is the most potent enzyme inhibitor that exists; it is in a class of its own and well deserves its title as the most toxic non-radioactive element. Since mercury and lead attach themselves at these highly vulnerable junctures of proteins, they can readily provoke biochemical shifts and then morphological changes in the body. Transsulfuration pathways in the body are fundamental for life. When mercury blocks thiol groups, cellular proteins lose their reactive properties and lose their ability to carry out their routine function.
“If you not getting the hint, I will say it outright! Sulfur is crucial for detoxification and chelation of heavy metals and radioactive particles, which behave like heavy metals chemically.”
__http://drsircus.com/medicine/cancer/cancer-sulfur-garlic-glutathione
With all that, I decided some MSM was was in order.
Let me back up just one minute for reasons that will become apparent. Roughly 3-4 weeks after beginning iodine in November, at ~2-3 mg day, I began having very cloudy urine, much more perspiration and horrible body odor, as many others have reported, and seems attributable to bromine/fluorine excretion. This lasted 2 or 3 weeks and ceased by the end of December. I figured great, that’s all done. Not so fast…
Fast forward to two weeks ago and first dose of MSM. Within an hour I had a horrible pounding/throbbing headache. I’ve never had many issues with headaches so I thought maybe I was just being a wimp. Searching MSM+headache you’ll find folks who regularly suffer migraines complaining how wicked it is. Within 3-4 hours of the dose I began peeing the same cloudy, stinky urine as back in December, and did so for the next two days! Headache continued the next day along with some insomnia (another common report with MSM), and there were some aches/pains/tingling in my “fibro” spots, tooth and jaw aches, and some anxiety/jitteriness.
On the third day I woke up, and my hypo symptoms were gone, all of them!!! Throat no issues, skin is now supple, and body temperature back to normal, enough energy in afternoon to do some spring cleaning, as opposed to nearly passing out after lunch!
As the headache was still fairly intense on second day, I waited until third to take another dose. Headache returned, so I began investigating that. Turns out molybdenum can help with it, and I just happened to have some as was taking it earlier to help with candida die off products, along with pantethine.
“Sulfur of any sort is metabolized in the body into a harmless compound called sulfate by the enzyme sulfite oxidase. But sulfite oxidase depends on the trace element molybdenum to do its job. Without enough molybdenum, sulfite oxidase doesn’t transform sulfite into sulfate efficiently, excess sulfite builds up, and any or all of the above-noted symptoms can occur.
Although there’s presently no recommended daily intake for molybdenum, it’s a general consensus that if there were one it would be in the neighborhood of 200-300 micrograms daily. However, it’s been my experience from many cases that molybdenum absorbs poorly when taken orally. Usually at least 1,000 micrograms twice daily are needed to relieve symptoms.”
__http://nutritionandhealing.com/2012/10/22/save-your-head-with-this-addition-to-your-arthritis-treatment/
“MSM has proven useful for many people in treating a huge array of conditions, including arthritis, allergies, fatigue, asthma, back pain, sinusitis, carpal tunnel syndrome, autoimmune diseases, and thinning hair - just to name a few. But even though MSM isn't new on the health scene, there is one thing that you need to know when taking any supplement, like MSM, that contains significant amounts of sulfur for several months or longer.
You must be sure to take a small amount of molybdenum along with it. Molybdenum (pronounced mo-leb'-nee-um) is a trace element that your body needs in order to metabolize the sulfur, transport oxygen, and detoxify. Since this element is used up as it helps metabolize sulfur (and there's much too little in our food supply to make up for it), your body is sure to need extra.”
__http://altmedangel.com/msm.htm
500 mcg of molybdenum relieved the headache within an hour, and induced a lot of painless gurgling activity in the gut. I’m now taking 250 mcg in the am, 500 mcg with the MSM + 1000 mg Vit C, and then another 250 mcg at night.
MSM is ideally taken with 1000 mgs of Vitamin C., and taken i the morning as it can keep you up if taken in afternoon. Sort of throws a wrench into schedule for those taking Vit C in the afternoon. I have iodine/cofactors with breakfast, then MSM, Vit C, and extra molybdenum around 10-11 a.m. You can also pulse does it, which is what I’m doing now, 1000 mg for three days, then two days off.
Headaches are gone, urine slightly cloudy the days MSM taken, still some light perspiration/funky smell. That’s the worst of it. Also, a good idea to increase water intake (yes, yes everyone is already doing that but you may need to
double it with MSM for headache relief and to help flush everything out!). I can also now add iodine several milligrams with no hypo symptoms so will slowly work my way back up. Definitely opened a pathway which was not functioning!
One last note. If you have a one or two events with runny nose and sneezing, especially at first taking iodine, that is pretty normal it seems. If you are having recurrent sinus/cold/flu type flare ups and/or tummy issues (gnawing/rumbling/hunger pangs only temporarily relieved with eating), especially as you increase iodine, and spanning months, I would seriously look into candida flare up in conjunction with the detox pathway, and treat for same, whether that is strict diet adherence (which I wasn’t doing) and/or adding antifungals.